| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mitsuko Takenaga, Yuki Ohta, Yukie Tokura, Akemi Hamaguchi, Koichi Shudo, Hideyuki Okano, Rie Igarash. The effect of Am-80, a synthetic retinoid, on spinal cord injury-induced motor dysfunction in rats. Biological & pharmaceutical bulletin. vol 32. issue 2. 2009-03-12. PMID:19182380. |
on day 28 after injury, the lesion cavity was markedly reduced, while the expression of myelin basic protein (mbp; myelin), betaiiitubulin (neuron), and glial fibrillary acidic protein (gfap; astrocyte) was increased, in comparison with sci controls. |
2009-03-12 |
2023-08-12 |
rat |
| Ina B Wanner, Andres Deik, Miguel Torres, Andrew Rosendahl, Joseph T Neary, Vance P Lemmon, John L Bixb. A new in vitro model of the glial scar inhibits axon growth. Glia. vol 56. issue 15. 2009-03-05. PMID:18618667. |
our model displayed widespread morphological signs of astrocyte reactivity, increases in expression of glial fibrillary acidic protein (gfap), and accumulation of gfap in astrocytic processes. |
2009-03-05 |
2023-08-12 |
Not clear |
| Mohammed Sabri, Ayako Kawashima, Jinglu Ai, R Loch Macdonal. Neuronal and astrocytic apoptosis after subarachnoid hemorrhage: a possible cause for poor prognosis. Brain research. vol 1238. 2009-02-09. PMID:18786513. |
using antibodies against neuronal marker neuronal nuclear protein (neun) and astrocyte marker glial fibrillary acidic protein (gfap) in conjunction with apoptosis marker (cleaved caspase-3), we quantified neurons and astrocytes to monitor the degree of apoptosis in both groups. |
2009-02-09 |
2023-08-12 |
dog |
| Isabel Lastres-Becker, Antonio Fernández-Pérez, Beatriz Cebolla, Mario Vallej. Pituitary adenylate cyclase-activating polypeptide stimulates glial fibrillary acidic protein gene expression in cortical precursor cells by activating Ras and Rap1. Molecular and cellular neurosciences. vol 39. issue 3. 2009-01-29. PMID:18707003. |
pituitary adenylate cyclase-activating polypeptide (pacap) acts on cortical precursor cells to trigger glial fibrillary acidic protein (gfap) gene expression and astrocyte differentiation by stimulation of intracellular camp production. |
2009-01-29 |
2023-08-12 |
Not clear |
| Nursel Türkmen, Bülent Eren, Recep Fedakar, Semra Akgöz, Nil Comunoğl. Glial fibrillary acidic protein (GFAP) and CD34 expression in the human optic nerve and brain in methanol toxicity. Advances in therapy. vol 25. issue 2. 2009-01-22. PMID:18288452. |
glial fibrillary acidic protein (gfap) immunostaining is the most commonly used method for examining astrocyte proliferation and hypertrophy after various central nervous system injuries. |
2009-01-22 |
2023-08-12 |
human |
| Xueren Zhao, Fredric A Gorin, Robert F Berman, Bruce G Lyet. Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats. Journal of neurotrauma. vol 25. issue 10. 2009-01-16. PMID:18847376. |
stereological analysis of the ca2/3 sub-regions of the hippocampus demonstrated that higher doses of kb-r7943 (2 and 20 nmoles) significantly reduced astrocyte gfap immunoreactivity compared to vehicle-treated animals. |
2009-01-16 |
2023-08-12 |
rat |
| Xueren Zhao, Fredric A Gorin, Robert F Berman, Bruce G Lyet. Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats. Journal of neurotrauma. vol 25. issue 10. 2009-01-16. PMID:18847376. |
eipa (2-200 nmoles) did not alter astrocyte gfap immunoreactivity. |
2009-01-16 |
2023-08-12 |
rat |
| Xueren Zhao, Fredric A Gorin, Robert F Berman, Bruce G Lyet. Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats. Journal of neurotrauma. vol 25. issue 10. 2009-01-16. PMID:18847376. |
amiloride (100 nmoles) significantly attenuated the tbi-induced acute reduction in astrocyte gfap immunoreactivity. |
2009-01-16 |
2023-08-12 |
rat |
| Annadora J Bruce-Keller, Jadwiga Turchan-Cholewo, Eric J Smart, Theresa Geurin, Ashok Chauhan, Rollie Reid, Ruqiang Xu, Avindra Nath, Pamela E Knapp, Kurt F Hause. Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV-1 Tat transgenic mice. Glia. vol 56. issue 13. 2009-01-13. PMID:18551626. |
to better understand how opiates could alter hiv-related brain inflammation, the expression of astrocyte (gfap immunoreactivity) and macrophage/microglial (f4/80 or mac1 immunoreactivity) markers in the striatum, and the percentage of 3-nitrotyrosine (3-nt) positive macrophages/microglia, was determined following a 2-day exposure to morphine (5 mg/kg/day via time-release, subcutaneous implant) and doxycycline in gfap-driven, doxycycline-inducible hiv-1 tat transgenic mice. |
2009-01-13 |
2023-08-12 |
mouse |
| Wei-Lin Liu, Yi-Hsuan Lee, Shih-Ying Tsai, Chung Yi Hsu, Yu-Yo Sun, Liang-Yo Yang, Shing-Han Tsai, Wei-Chung Vivian Yan. Methylprednisolone inhibits the expression of glial fibrillary acidic protein and chondroitin sulfate proteoglycans in reactivated astrocytes. Glia. vol 56. issue 13. 2009-01-13. PMID:18618653. |
the expression of glial fibrillary acidic protein (gfap), a marker of astrocyte reactivation, and cspg neurocan and phosphacan were significantly elevated by ampa treatment. |
2009-01-13 |
2023-08-12 |
rat |
| Chandrakumar Balaratnasingam, William H Morgan, Louise Bass, Linda Ye, Charlotte McKnight, Stephen J Cringle, Dao-Yi Y. Elevated pressure induced astrocyte damage in the optic nerve. Brain research. vol 1244. 2009-01-12. PMID:18848926. |
using glial fibrillary acidic protein (gfap) as a marker of astrocytes we have now studied pressure induced changes in astrocyte structure in the optic nerve head. |
2009-01-12 |
2023-08-12 |
Not clear |
| Manoj Kumar Mishra, Kanhaiya Lal Kumawat, Anirban Bas. Japanese encephalitis virus differentially modulates the induction of multiple pro-inflammatory mediators in human astrocytoma and astroglioma cell-lines. Cell biology international. vol 32. issue 12. 2009-01-09. PMID:18801452. |
the expression of different proteins such as astrocyte-specific glial fibrillary acidic protein (gfap), the glutamate aspartate transporter/essential amino acid transporter-1 (glast/eaat-1), glutamate transporter-1/essential amino acid transporter-2 (glt-1/eaat-2), ceruloplasmin and thioredoxin (trx) expression level also differ in different human astrocyte cell-lines following infection. |
2009-01-09 |
2023-08-12 |
human |
| Izuho Hatada, Masakazu Namihira, Sumiyo Morita, Mika Kimura, Takuro Horii, Kinichi Nakashim. Astrocyte-specific genes are generally demethylated in neural precursor cells prior to astrocytic differentiation. PloS one. vol 3. issue 9. 2008-11-25. PMID:18784832. |
this differentiation-potential switch could be explained by epigenetic changes, since the promoters of astrocyte-specific marker genes, glial fibrillary acidic protein (gfap) and s100beta, have been shown to become demethylated in late-stage npcs prior to the onset of astrocyte differentiation; however, whether demethylation occurs generally in other astrocyctic genes remains unknown. |
2008-11-25 |
2023-08-12 |
mouse |
| Yurii V Lebed, Maxim A Orlovsky, Alexander G Nikonenko, Galina A Ushakova, Galina G Skib. Early reaction of astroglial cells in rat hippocampus to streptozotocin-induced diabetes. Neuroscience letters. vol 444. issue 2. 2008-11-18. PMID:18708122. |
astrocyte count, size and shape as well as levels of glial fibrillary acidic protein (gfap) and s100b protein were assessed 3, 7 and 14 days after the stz injection using immunohistochemistry, immuno-enzyme assay and computer-assisted image analysis. |
2008-11-18 |
2023-08-12 |
rat |
| Jun Mo Kang, Jae-Chul Jung, Heejeong Kim, Heena Lim, Soyong Jang, Seikwan O. Neuroprotective effect of benzylideneacetophenone derivative on the MPTP model of neurodegeneration in mice. Archives of pharmacal research. vol 31. issue 9. 2008-10-28. PMID:18806951. |
immunohistochemistry and western blot were used to determine the expression levels of tyrosine hydroxylase (th), dopamine transporter (dat), ox-42 (a marker of microglial activation), and glial fibrillary acid protein (gfap, a marker of astrocyte activation) in the substantia nigra (sn) and striatum (st). |
2008-10-28 |
2023-08-12 |
mouse |
| Luciana Ferreira Romão, Vivian de Oliveira Sousa, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-beta1 pathways. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18419760. |
we recently demonstrated that cortical neurons activate the gene promoter of the astrocyte maturation marker, gfap (glial fibrillary acidic protein) of cerebral cortex astrocytes by inducing tgf-beta1 (transforming growth factor beta 1) secretion in vitro. |
2008-09-16 |
2023-08-12 |
mouse |
| Luciana Ferreira Romão, Vivian de Oliveira Sousa, Vivaldo Moura Neto, Flávia Carvalho Alcantara Gome. Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-beta1 pathways. Journal of neurochemistry. vol 106. issue 2. 2008-09-16. PMID:18419760. |
together, our results suggest that glial metabotropic glutamate 2/3 receptor activation by neurons induces tgf-beta1 secretion, leading to gfap gene activation and astrocyte differentiation and involves smad and mapk/pi3k pathways. |
2008-09-16 |
2023-08-12 |
mouse |
| R A Barreto, C S Sousa, V D A Silva, A R Silva, E S Veloso, S D Cunha, M F D Costa, R S El-Bachá, S L Cost. Monocrotaline pyrrol is cytotoxic and alters the patterns of GFAP expression on astrocyte primary cultures. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 5. 2008-08-29. PMID:18474415. |
monocrotaline pyrrol is cytotoxic and alters the patterns of gfap expression on astrocyte primary cultures. |
2008-08-29 |
2023-08-12 |
rat |
| E Philip Jesudason, J Gunasingh Masilamoni, Charles E Jebaraj, Solomon F D Paul, R Jayakuma. Efficacy of DL-alpha lipoic acid against systemic inflammation-induced mice: antioxidant defense system. Molecular and cellular biochemistry. vol 313. issue 1-2. 2008-08-18. PMID:18401559. |
in addition, increased immunoreactivity of the astrocyte marker glial fibrillary acidic protein (gfap) was observed in the neocortex region of inflammation-induced mice, whereas nuclear factor kappa b p65 (nfkappab) immunoreactivity was observed in both the neocortex and liver of the same group which were effectively controlled by la therapy suggesting that la can efficiently manage systemic inflammation. |
2008-08-18 |
2023-08-12 |
mouse |
| Michael A Galic, Kiarash Riazi, James G Heida, Abdeslam Mouihate, Neil M Fournier, Sarah J Spencer, Lisa E Kalynchuk, G Campbell Teskey, Quentin J Pittma. Postnatal inflammation increases seizure susceptibility in adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 27. 2008-08-12. PMID:18596165. |
postnatal lps injection did not result in permanent changes in microglial (iba1) activity or hippocampal cytokine [il-1beta (interleukin-1beta) and tnfalpha] levels, but caused a slight increase in astrocyte (gfap) numbers. |
2008-08-12 |
2023-08-12 |
rat |