Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Maggie Lum, Alisa Turbic, Branka Mitrovic, Ann M Turnle. Fibroblast growth factor-9 inhibits astrocyte differentiation of adult mouse neural progenitor cells. Journal of neuroscience research. vol 87. issue 10. 2009-08-31. PMID:19267409. |
the most marked effect on differentiation was an almost total lack of glial fibrillary acidic protein (gfap)-positive astrocytes up to 7 days following fgf9 addition, indicating that astrocyte differentiation was strongly inhibited. |
2009-08-31 |
2023-08-12 |
mouse |
S Saadoun, M J Tait, A Reza, D Ceri Davies, B A Bell, A S Verkman, M C Papadopoulo. AQP4 gene deletion in mice does not alter blood-brain barrier integrity or brain morphology. Neuroscience. vol 161. issue 3. 2009-08-24. PMID:19345723. |
neurons, astrocytes and oligodendrocytes were assessed using the neuronal nuclear marker neun, the astrocyte marker gfap, and the myelin stain luxol fast blue. |
2009-08-24 |
2023-08-12 |
mouse |
W Xie, J A Strong, J-M Zhan. Early blockade of injured primary sensory afferents reduces glial cell activation in two rat neuropathic pain models. Neuroscience. vol 160. issue 4. 2009-08-14. PMID:19303429. |
local perfusion in the snl model also significantly reduced microglia activation (ox-42 immunoreactivity) on day 3 and astrocyte activation (gfap immunoreactivity) on day 10 in the corresponding dorsal spinal cord. |
2009-08-14 |
2023-08-12 |
rat |
Pamella Huey Mei Wang, Telma T Schwindt, Gabriela Filoso Barnabé, Fabiana L T Motta, Patricia Semedo, Felipe Caetano Beraldo, Marilda Mazzali, Marlene Antonia Dos Reis, Vicente de Paula Antunes Teixeira, Alvaro Pacheco-Silva, Luis Eugênio A de Mello, Niels Olsen Saraiva Câmar. Administration of neural precursor cells ameliorates renal ischemia-reperfusion injury. Nephron. Experimental nephrology. vol 112. issue 1. 2009-08-11. PMID:19342870. |
npc-cfse and glial fibrillary acidic protein (gfap)-positive cells (astrocyte marker) were found exclusively in renal parenchyma, which also presented gfap and sox-2 (an embryonic neural stem cell marker) mrna expression. |
2009-08-11 |
2023-08-12 |
rat |
Giordano G Viola, Letícia Rodrigues, João C Américo, Gisele Hansel, Rafael S Vargas, Regina Biasibetti, Alessandra Swarowsky, Carlos A Gonçalves, Léder L Xavier, Matilde Achaval, Diogo O Souza, Olavo B Amara. Morphological changes in hippocampal astrocytes induced by environmental enrichment in mice. Brain research. vol 1274. 2009-07-29. PMID:19374889. |
after 8 weeks of environmental enrichment starting at weaning, male cf-1 mice presented no significant changes in astrocyte number or in the density of glial fibrillary acidic protein (gfap) immunoreactivity in the stratum radiatum. |
2009-07-29 |
2023-08-12 |
mouse |
Mohammad Shyful Islam, Kouko Tatsumi, Hiroaki Okuda, Sadao Shiosaka, Akio Wanak. Olig2-expressing progenitor cells preferentially differentiate into oligodendrocytes in cuprizone-induced demyelinated lesions. Neurochemistry international. vol 54. issue 3-4. 2009-07-28. PMID:19070638. |
after 6 weeks of cuprizone exposure, gfp-positive (gfp(+)) cells were processed for a second labeling with antibodies to major neural cell markers apc (mature oligodendrocyte marker), gfap (astrocyte marker), neun (neuron marker), iba1 (microglia marker) and ng2 proteoglycan (oligodendrocyte progenitor marker). |
2009-07-28 |
2023-08-12 |
mouse |
Doo-Sik Kim, Katherine W Figueroa, Kang-Wu Li, Amin Boroujerdi, Tim Yolo, Z David Lu. Profiling of dynamically changed gene expression in dorsal root ganglia post peripheral nerve injury and a critical role of injury-induced glial fibrillary acidic protein in maintenance of pain behaviors [corrected]. Pain. vol 143. issue 1-2. 2009-07-20. PMID:19307059. |
together, these findings indicate that injury-induced gfap upregulation not only serves as a marker for astrocyte activation, but it may also play a critical, but yet identified, role in the maintenance of neuropathic pain states. |
2009-07-20 |
2023-08-12 |
mouse |
Steven J Mullett, Ronald L Hamilton, David A Hinkl. DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 29. issue 2. 2009-07-17. PMID:18647263. |
the studies presented here show that dj-1 is abundantly expressed in reactive infarct region astrocytes in both gray and white matter, that subacute and chronic infarct region astrocytes are much more robustly dj-1+ than are acute infarct and non-infarct region astrocytes, and that dj-1 staining intensity in astrocytes generally correlates with that of the reactive astrocyte marker gfap. |
2009-07-17 |
2023-08-12 |
human |
Brian W Leonard, Diego Mastroeni, Andrew Grover, Qiang Liu, Kechun Yang, Ming Gao, Jie Wu, David Pootrakul, Simone A van den Berge, Elly M Hol, Joseph Roger. Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. The Journal of comparative neurology. vol 515. issue 3. 2009-07-13. PMID:19425077. |
histological sections of svz from these cases showed a glial fibrillary acidic protein (gfap)-positive ribbon of astrocytes similar to the astrocyte ribbon in human periventricular white matter biopsies that is reported to be a rich source of neural progenitors. |
2009-07-13 |
2023-08-12 |
mouse |
Janet L Anderl, Stella Redpath, Andrew J Bal. A neuronal and astrocyte co-culture assay for high content analysis of neurotoxicity. Journal of visualized experiments : JoVE. issue 27. 2009-06-30. PMID:19417729. |
astrocytic activation (gliosis) leads to the upregulation of gfap, commonly accompanied by astrocyte proliferation and hypertrophy. |
2009-06-30 |
2023-08-12 |
human |
Janet L Anderl, Stella Redpath, Andrew J Bal. A neuronal and astrocyte co-culture assay for high content analysis of neurotoxicity. Journal of visualized experiments : JoVE. issue 27. 2009-06-30. PMID:19417729. |
we determined that hca could be used to overcome these limitations and to simultaneously measure multiple features associated with gliosis - changes in gfap expression, astrocyte hypertrophy, and astrocyte proliferation - within a single assay. |
2009-06-30 |
2023-08-12 |
human |
Weigang Gu, Thomas Brännström, Roland Rosqvist, Per Weste. Cell division in the cerebral cortex of adult rats after photothrombotic ring stroke. Stem cell research. vol 2. issue 1. 2009-05-27. PMID:19383410. |
cell type was ascertained by double immunolabeling with the neuronal markers map-2ab/beta-tubulin iii and neun/hu or the astrocyte marker gfap. |
2009-05-27 |
2023-08-12 |
rat |
Xu Wang, Terry L LeVatte, Michele L Archibald, Balwantray C Chauha. Increase in endothelin B receptor expression in optic nerve astrocytes in endothelin-1 induced chronic experimental optic neuropathy. Experimental eye research. vol 88. issue 3. 2009-05-26. PMID:18938160. |
etb-positive cells almost completely co-localized with gfap-positive cells in both experimental and untreated control nerves, however, etb expression was stronger in the astrocyte soma and proximal processes, while gfap was expressed more strongly in the distal processes. |
2009-05-26 |
2023-08-12 |
rat |
Lei Qiang, Yong Yang, Yan-Jun Ma, Fei-Hong Chen, Ling-Bo Zhang, Wei Liu, Qi Qi, Na Lu, Lei Tao, Xiao-Tang Wang, Qi-Dong You, Qing-Long Gu. Isolation and characterization of cancer stem like cells in human glioblastoma cell lines. Cancer letters. vol 279. issue 1. 2009-05-14. PMID:19232461. |
they expressed the neural stem cell markers cd133 and nestin, but lacked of neuronal and astrocyte marker map2, beta-iii tubulin and gfap. |
2009-05-14 |
2023-08-12 |
human |
Woosung Cho, Albee Messin. Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice. Experimental cell research. vol 315. issue 7. 2009-05-06. PMID:19146851. |
however, identification of the critical astrocyte functions that are compromised by mis-expression of gfap has not yet been possible. |
2009-05-06 |
2023-08-12 |
mouse |
Woosung Cho, Albee Messin. Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice. Experimental cell research. vol 315. issue 7. 2009-05-06. PMID:19146851. |
to provide new tools for investigating the nature of astrocyte dysfunction in alexander disease, we have established primary astrocyte cultures from two mouse models of alexander disease, a transgenic that over-expresses wild type human gfap, and a knock-in at the endogenous mouse locus that mimics a common alexander disease mutation. |
2009-05-06 |
2023-08-12 |
mouse |
Woosung Cho, Albee Messin. Properties of astrocytes cultured from GFAP over-expressing and GFAP mutant mice. Experimental cell research. vol 315. issue 7. 2009-05-06. PMID:19146851. |
we find that mutant gfap, as well as excess wild type gfap, promotes formation of cytoplasmic inclusions, disrupts the cytoskeleton, decreases cell proliferation, increases cell death, reduces proteasomal function, and compromises astrocyte resistance to stress. |
2009-05-06 |
2023-08-12 |
mouse |
Clorinda Arias, Angélica Zepeda, Karina Hernández-Ortega, Perla Leal-Galicia, Cinthia Lojero, Ignacio Camacho-Arroy. Sex and estrous cycle-dependent differences in glial fibrillary acidic protein immunoreactivity in the adult rat hippocampus. Hormones and behavior. vol 55. issue 1. 2009-03-31. PMID:19056393. |
the marked sex and estrous cycle-dependent differences in gfap immunoreactivity density and in astrocyte number and morphology found in the rat hippocampus, suggest the involvement of sex steroid hormones in the sexually dimorphic functions of the hippocampus, and in the change in its activity during the estrous cycle. |
2009-03-31 |
2023-08-12 |
rat |
Vincenzo Bramanti, Daniela Bronzi, Giuseppina Raciti, Marcello Avitabile, Roberto Avol. Neurosteroid-growth factor cross-talk induces up and down regulation of GFAP and vimentin expression in serum free astrocyte cultures. The Italian journal of biochemistry. vol 56. issue 4. 2009-03-31. PMID:19192631. |
neurosteroid-growth factor cross-talk induces up and down regulation of gfap and vimentin expression in serum free astrocyte cultures. |
2009-03-31 |
2023-08-12 |
Not clear |
Ariane Zamoner, Luana Heimfarth, Regina Pessoa-Pureu. Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. Neurotoxicology. vol 29. issue 6. 2009-03-26. PMID:18845185. |
this treatment induced hyperphosphorylation of neurofilaments, the neuronal intermediate filament (if) proteins, of heavy, medium and low molecular weight (nf-h, nf-m and nf-l, respectively) without altering the phosphorylation level of astrocyte if proteins, glial fibrillary acidic protein (gfap) and vimentin in cerebral cortex of rats. |
2009-03-26 |
2023-08-12 |
rat |