| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan Xie, Li Li, Min Peng, Huan Zhan. Overexpression of miR-199a-5p improves brain injury in newborn rats with intrauterine infection via inhibition of astrocyte activation. Brain research. 2023-08-30. PMID:37648092. |
results from cell models showed that mir-199a-5p overexpression inhibited astrocyte activation, shown by enhanced cell viability, weakened cell apoptosis, and decreased gfap, il-6, and tnf-α. |
2023-08-30 |
2023-09-07 |
rat |
| Guadalupe Herrera, M Jazmín Silvero C, M Cecilia Becerra, Mercedes Lasaga, Teresa Scimonell. Modulatory role of α-MSH in hippocampal-dependent memory impairment, synaptic plasticity changes, oxidative stress, and astrocyte reactivity induced by short-term high-fat diet intake. Neuropharmacology. 2023-08-17. PMID:37591460. |
we observed astrocyte proliferation and a significant increase in the percentage of the area occupied by gfap. |
2023-08-17 |
2023-09-07 |
rat |
| Marc Alain Züst, Christian Mikutta, Ximena Omlin, Tatjana DeStefani, Marina Wunderlin, Céline Jacqueline Zeller, Kristoffer Daniel Fehér, Elisabeth Hertenstein, Carlotta L Schneider, Charlotte Elisabeth Teunissen, Leila Tarokh, Stefan Klöppel, Bernd Feige, Dieter Riemann, Christoph Nisse. The hierarchy of coupled sleep oscillations reverses with aging in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-08-16. PMID:37586871. |
in older adults, deteriorating slow wave-spindle coupling, measured using phase slope index (psi) and number of coupling events, is associated with blood plasma glial fibrillary acidic protein (gfap) levels, a marker for astrocyte activation. |
2023-08-16 |
2023-09-07 |
human |
| Dhanny Primantara Johari Santoso, Annisa Dewi Nugrahani, Amillia Siddiq, Akhmad Yogi Pramatirta, Muhammad Alamsyah Aziz, Setyorini Irianti, Adhi Pribadi, Anita Deborah Anwar, Jusuf Sulaeman Effend. Effect of maternal serum magnesium and calcium levels on umbilical glial fibrillary acidic protein levels in preterm labor. Scientific reports. vol 13. issue 1. 2023-08-16. PMID:37587163. |
magnesium can prevent astrocyte cell death and glial fibrillary acidic protein (gfap) secretion as inflammatory marker in preterm delivery. |
2023-08-16 |
2023-09-07 |
Not clear |
| Diulle Spat Peres, Fernanda Tibolla Viero, Patrícia Rodrigues, Laura de Barros Bernardes, Náthaly Andriguetto Ruviaro da Silva, Igor Ramos Lima, Gabrielli Martins, Paulo Cesar Lock Silveira, Marcella de Amorim Ferreira, Ana Merian Silva, Juliano Ferreira, Gabriela Trevisa. Characterization of Depression- and Anxiety-Like Behaviours in a Mouse Model of Relapsing-Remitting Multiple Sclerosis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2023-08-01. PMID:37526817. |
also, increased levels of tumour necrosis factor alpha (tnf-α), astrocyte marker (gfap), and microglial markers (iba-1) were detected in the prefrontal cortex at 35 p.i. |
2023-08-01 |
2023-08-14 |
mouse |
| Zhi-Ling Zhang, Zhi-Tong Wang, Jing Shi, Xiao-Ping Pu, Suo-Di Zha. Tetrandrine attenuates SNI-induced mechanical allodynia by inhibiting spinal CKLF1. Neuropharmacology. 2023-07-30. PMID:37517461. |
western blotting and immunofluorescence staining showed that tet significantly inhibited spinal protein expression levels of cklf1, p-nf-κb/nf-κb, p-ikk/ikk, pro-inflammatory cytokines il-1β and tnf-α, and increased protein expression levels of the anti-inflammatory cytokine il-10, while inhibiting the expression levels of microglia and astrocyte markers iba-1 and gfap of sni mice. |
2023-07-30 |
2023-08-14 |
mouse |
| Thomas Jacobus Geus, Glenn Franken, Bert Bert Jooste. Conventional, High Frequency and Differential Targeted Multiplexed Spinal Cord Stimulation in experimental Painful Diabetic Peripheral Neuropathy: pain behavior and role of the central inflammatory balance. Molecular pain. 2023-07-25. PMID:37488684. |
the inflammatory balance and glial response were analyzed in the dorsal spinal cord based on rna expression of pro- and anti-inflammatory cytokines (tnf-α, il-1ß, il-4, il-10), a microglia marker (itgam), an astrocyte marker (gfap), a t-cell marker (cd3d), microglia proliferation markers (irf8, adgre1) and p2x4, p13-mapk, bdnf signaling markers (p2x4, mapk14, bdnf). |
2023-07-25 |
2023-08-14 |
Not clear |
| Geiza Fernanda Antunes, Ana Carolina Pinheiro Campos, Daniel de Oliveira Martins, Flavia Venetucci Gouveia, Miguel José Rangel Junior, Rosana Lima Pagano, Raquel Chacon Ruiz Martine. Unravelling the Role of Habenula Subnuclei on Avoidance Response: Focus on Activation and Neuroinflammation. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445871. |
the present study aimed to shed light on the habenula subnuclei signature in avoidance behavior, evaluating the pattern of neuronal activation using fos expression and astrocyte density using gfap immunoreactivity, and comparing control, good and poor performers. |
2023-07-14 |
2023-08-14 |
Not clear |
| Maiko Inoue, Takashi Tanida, Tomohiro Kondo, Shigeo Takenaka, Takayuki Nakajim. Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture. The Journal of veterinary medical science. 2023-07-05. PMID:37407448. |
therefore, applying ogd to ngc cells could serve as a useful in vitro tool to elucidate the molecular mechanisms underlying brain ischemia-induced changes in gfap expression, astrocyte proliferation, and m1 microglia phenotype-related gene expression. |
2023-07-05 |
2023-08-14 |
rat |
| Rita Chaaya, Joel R Steele, Brian G Oliver, Hui Chen, Rita Machaalan. Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus. Journal of chemical neuroanatomy. 2023-06-21. PMID:37343645. |
this study, using a mouse model, investigated the effects of exposure to e-vapour (± nicotine) and hfd (43% fat) consumption, on the expression of nicotinic acetylcholine receptor (nachr) subunits α3, α4, α7 and β2, apoptosis markers caspase-3 and tunel, microglial marker iba-1, and astrocyte marker gfap, in hippocampal subregions of dentate gyrus (dg) and cornu ammonis (ca) 1-3. |
2023-06-21 |
2023-08-14 |
mouse |
| Susan C Schwerin, Nicholas Breehl, Adedunsola Obasa, Yeonho Kim, Joseph McCabe, Daniel P Perl, Thaddeus Haight, Sharon L Julian. Actigraphic evidence of persistent sleep disruption following repetitive mild traumatic brain injury in a gyrencephalic model. Cerebral cortex (New York, N.Y. : 1991). 2023-06-13. PMID:37310176. |
at 4 weeks post injury, the reactive astrocyte (gfap) immunoreactivity was significantly greater in both the injury groups compared to sham, but did not differ at 6 months post injury. |
2023-06-13 |
2023-08-14 |
Not clear |
| Laura Jahnke, Souska Zandi, Ahmed Elhelbawi, Federica Maria Conedera, Volker Enzman. Characterization of Macroglia Response during Tissue Repair in a Laser-Induced Model of Retinal Degeneration. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298126. |
immunofluorescence was performed to evaluate müller cell (gs) and astrocyte (gfap) injury response and to distinguish between both cell types. |
2023-06-11 |
2023-08-14 |
mouse |
| Nundehui Díaz-Lezama, Jacqueline Kajtna, Jiou Wu, Monika Ayten, Susanne F Koc. Microglial and macroglial dynamics in a model of retinitis pigmentosa. Vision research. vol 210. 2023-06-09. PMID:37295269. |
we demonstrated an increased number of activated microglia, retraction of microglial processes, reactive gliosis of müller cells, astrocyte remodelling and an upregulation of glial fibrillary acidic protein (gfap) in response to photoreceptor degeneration. |
2023-06-09 |
2023-08-14 |
mouse |
| Bayan M Saleh, Ayda Pourmostafa, Nashaita Y Patrawalla, Vipuil Kishor. Xeno-Free Biomimetic ECM Model for Investigation of Matrix Composition and Stiffness on Astrocyte Cell Response. Journal of functional biomaterials. vol 14. issue 5. 2023-05-26. PMID:37233366. |
soft hydrogels trigger astrocyte activation indicated by greater cell spreading, high gfap expression and low aldh1l1 expression. |
2023-05-26 |
2023-08-14 |
human |
| Ronald J Ellis, Yan Fan, David Grelotti, Bin Tang, Scott Letendre, Johnny J H. Astrocyte Activation is A Potential Mechanism Underlying Depressed Mood and Apathy in People with HIV. Journal of neurology and psychology. vol 9. issue 1. 2023-05-19. PMID:37205974. |
we tested the hypothesis that depression and apathy in pwh would be associated with higher levels of a biomarker of astrocyte activation, glial fibrillary acidic protein (gfap), in cerebrospinal fluid (csf). |
2023-05-19 |
2023-08-14 |
Not clear |
| Yi-Wen Bai, Qi-Hao Yang, Pei-Jie Chen, Xue-Qiang Wan. Repetitive transcranial magnetic stimulation regulates neuroinflammation in neuropathic pain. Frontiers in immunology. vol 14. 2023-05-14. PMID:37180127. |
in addition, rtms reduces the expression of glutamate receptors (mglur5 and nmdar2b) and microglia and astrocyte markers (iba1 and gfap). |
2023-05-14 |
2023-08-14 |
Not clear |
| Elmira Jalilian, Su Ryon Shi. Novel model of cortical-meningeal organoid co-culture system improves human cortical brain organoid cytoarchitecture. Scientific reports. vol 13. issue 1. 2023-05-14. PMID:37183210. |
finally, meningeal-encapsulated organoids enhanced outer radial glial and astrocyte formation illustrated by stronger expression of hopx and gfap markers, respectively. |
2023-05-14 |
2023-08-14 |
human |
| Fatemeh Abbaszadeh, Masoumeh Jorjani, Mohammad Taghi Joghataei, Samira Raminfard, Soraya Mehrab. Astaxanthin ameliorates spinal cord edema and astrocyte activation via suppression of HMGB1/TLR4/NF-κB signaling pathway in a rat model of spinal cord injury. Naunyn-Schmiedeberg's archives of pharmacology. 2023-05-05. PMID:37145127. |
we showed that ast potentially improved the recovery of motor function and inhibited the spinal cord edema via maintaining the integrity of bscb, reducing the expression of hmgb1, tlr4, and nf-κb, mmp-9 as well as downregulation of astrocyte activation (gfap) and aqp4 expression. |
2023-05-05 |
2023-08-14 |
rat |
| Ana Lucia Tavares-Gomes, Bruna Teixeira-Silva, Beatriz Bastos de Moraes Thomasi, Pablo Trindade, Sheila Espírito-Santo, Adriana da Cunha Faria Melibeu, Claudio Alberto Serfaty, Paula Campello-Cost. Retinotectal plasticity induced by monocular enucleation during the critical period is dependent of A2a adenosine receptor: A possible role of astrocytes. Experimental neurology. 2023-04-28. PMID:37116638. |
glial fibrillary acidic protein (gfap), an astrocyte marker, is up-regulated after central nervous system injury. |
2023-04-28 |
2023-08-14 |
rat |
| Fernando Laso-García, Laura Casado-Fernández, Dolores Piniella, Mari Carmen Gómez-de Frutos, Jone Karmele Arizaga-Echebarria, María Pérez-Mato, Elisa Alonso-López, Laura Otero-Ortega, Susana Belén Bravo, María Del Pilar Chantada-Vázquez, José Avendaño-Ortiz, Eduardo López-Collazo, María Isabel Lumbreras-Herrera, Angelo Gámez-Pozo, Blanca Fuentes, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, María Alonso de Leciñan. Circulating extracellular vesicles promote recovery in a preclinical model of intracerebral hemorrhage. Molecular therapy. Nucleic acids. vol 32. 2023-04-24. PMID:37090418. |
at 28 days, both treatments improved the motor function assessment scales score, showed greater fiber preservation in the perilesional zone (diffusion tensor-fractional anisotropy mri), increased immunofluorescence markers of myelin (mog), and decreased astrocyte markers (gfap) compared with controls. |
2023-04-24 |
2023-08-14 |
rat |