| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Damien C Boorman, Kevin A Kea. Sex differences in morphine sensitivity are associated with differential glial expression in the brainstem of rats with neuropathic pain. Journal of neuroscience research. 2022-07-19. PMID:35853016. |
morphine administration had small sex-dependent effects on overall gfap expression, but not on astrocyte morphology, in the rostral ventromedial medulla, the subnucleus reticularis dorsalis, and the area postrema. |
2022-07-19 |
2023-08-14 |
rat |
| Sarah A Abd El-Aal, Mohamed AbdElrahman, Ahmed M Reda, Hassan Afify, Ghada M Ragab, Amira A El-Gazar, Sherihan Salaheldin Abdelhamid Ibrahi. Galangin Mitigates DOX-induced Cognitive Impairment in Rats: Implication of NOX-1/Nrf-2/HMGB1/TLR4 and TNF-α/MAPKs/RIPK/MLKL/BDNF. Neurotoxicology. 2022-07-17. PMID:35843304. |
this inhibitory impact extended to entail astrocyte activation, as evidenced by the diminution of gfap. |
2022-07-17 |
2023-08-14 |
rat |
| Dan Zhu, Tingting Fan, Yaohua Chen, Xingyue Huo, Yuping Li, Danyong Liu, Yin Cai, Chi Wai Cheung, Jing Tang, Jian Cui, Zhengyuan Xi. CXCR4/CX43 Regulate Diabetic Neuropathic Pain via Intercellular Interactions between Activated Neurons and Dysfunctional Astrocytes during Late Phase of Diabetes in Rats and the Effects of Antioxidant N-Acetyl-L-Cysteine. Oxidative medicine and cellular longevity. vol 2022. 2022-07-08. PMID:35799894. |
given that gfap and c-fos are, respectively, makers of astrocyte and neuronal activation, our findings suggest that cxcr4 as an inflammatory stimulation protein and cx43 as an intercellular signal transmission protein both may induce neurons excitability and astrocytes dysfunction in developing dnp. |
2022-07-08 |
2023-08-14 |
human |
| Ying Wei, Li Xiao, Weihao Fan, Jing Zou, Hong Yang, Bo Liu, Yi Ye, Di Wen, Linchuan Lia. Astrocyte Activation, but not Microglia, Is Associated with the Experimental Mouse Model of Schizophrenia Induced by Chronic Ketamine. Journal of molecular neuroscience : MN. 2022-07-08. PMID:35802289. |
meanwhile, immunofluorescence was used to evaluate the expression levels of iba-1 (a microglial marker) and gfap (an astrocyte marker) in the mouse hippocampus for any change. |
2022-07-08 |
2023-08-14 |
mouse |
| W Brad Hubbard, Gopal V Velmurugan, Emily P Brown, Patrick G Sulliva. Resilience of females to acute blood-brain barrier damage and anxiety behavior following mild blast traumatic brain injury. Acta neuropathologica communications. vol 10. issue 1. 2022-06-27. PMID:35761393. |
blast-induced neurovascular damage was explored by measuring expression of tight junction (tj) proteins (zonula occludens-1 (zo-1), occludin and claudin-5), glial fibrillary acidic protein (gfap) and astrocyte end-feet coverage around the blood-brain barrier (bbb). |
2022-06-27 |
2023-08-14 |
rat |
| Alana Gomes de Souza, Iardja Stéfane Lopes, Adriano José Maia Chaves Filho, Talita Matias Barbosa Cavalcante, João Victor Souza Oliveira, Michele Albuquerque Jales de Carvalho, Klistenes Alves de Lima, Paloma Marinho Jucá, Sabrina Silva Mendonça, Melina Mottin, Carolina Horta Andrade, Francisca Cléa Florenço de Sousa, Danielle S Macedo, Marta Maria de França Fontele. Neuroprotective effects of dimethyl fumarate against depression-like behaviors via astrocytes and microglia modulation in mice: possible involvement of the HCAR2/Nrf2 signaling pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2022-06-06. PMID:35665831. |
microglia (iba1) and astrocyte (gfap) marker expressions were evaluated by immunofluorescence analyzes and the cytokines tnf-α and il-iβ by immunoenzymatic assay. |
2022-06-06 |
2023-08-14 |
mouse |
| Xusheng Zhang, Mengting Wang, Bingyan Feng, Qiuyu Zhang, Jia Tong, Mingyong Wang, Chengbiao Lu, Shiyong Pen. Seizures in PPT1 Knock-In Mice Are Associated with Inflammatory Activation of Microglia. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628400. |
the increased expression of gfap were seen at an earlier age of 4 months, and such an increase reached its peak at age of 6 months, indicating that astrocyte activation precedes microglia. |
2022-05-28 |
2023-08-13 |
mouse |
| Katie L Bales, Alicia S Chacko, John M Nickerson, Jeffrey H Boatright, Machelle T Pardu. Treadmill exercise promotes retinal astrocyte plasticity and protects against retinal degeneration in a mouse model of light-induced retinal degeneration. Journal of neuroscience research. 2022-05-18. PMID:35582827. |
treadmill exercise in dim control and lird groups had increased astrocyte density, gfap labeling, branching, dendritic endpoints, and arborization. |
2022-05-18 |
2023-08-13 |
mouse |
| Choong-Hyun Lee, Tae-Kyeong Lee, Dae Won Kim, Soon Sung Lim, Il Jun Kang, Ji Hyeon Ahn, Joon Ha Park, Jae-Chul Lee, Choong-Hyo Kim, Yoonsoo Park, Moo-Ho Won, Soo Young Cho. Relationship between Neuronal Damage/Death and Astrogliosis in the Cerebral Motor Cortex of Gerbil Models of Mild and Severe Ischemia and Reperfusion Injury. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563487. |
the ischemia-induced increase of glial fibrillary acidic protein (gfap; a maker of astrocyte) expression in severe ischemia was significantly higher than that in mild ischemia. |
2022-05-14 |
2023-08-13 |
Not clear |
| Marina Fandaros, Yanzuo Liu, Yueming Hua, Yingtian Pan, David A Rubenstein, Congwu Du, Wei Yi. Cocaine affects astrocyte activation and iNOS expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553228. |
astrocyte activation was assessed by immunofluorescence microscopy for glial fibrillary acidic protein (gfap) expression. |
2022-05-13 |
2023-08-13 |
mouse |
| Marina Fandaros, Yanzuo Liu, Yueming Hua, Yingtian Pan, David A Rubenstein, Congwu Du, Wei Yi. Cocaine affects astrocyte activation and iNOS expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35553228. |
astrocyte activation and number were quantified using immunofluorescence microscopy (of gfap). |
2022-05-13 |
2023-08-13 |
mouse |
| Jessica Zilli, Anne Schänzer, Kathrin Büttner, Monika Kressin, Martin J Schmid. Quantitative and qualitative evaluation of the hippocampal cytoarchitecture in adult cats with regard to the pathological diagnosis of hippocampal sclerosis. PloS one. vol 17. issue 5. 2022-05-13. PMID:35560321. |
histological (hematoxylin and eosin, nissl) and immunohistochemical (neun, gfap) staining was performed to investigate neuron and astroglial cell populations, as well as the layer thickness of the pyramidal cell layer and granule cell layer. |
2022-05-13 |
2023-08-13 |
Not clear |
| Amir Rostami, Fatemeh Taleahmad, Narges Haddadzadeh-Niri, Ensiye Joneidi, Siamak Afshin-Majd, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Sinomenine Attenuates Trimethyltin-Induced Cognitive Decline via Targeting Hippocampal Oxidative Stress and Neuroinflammation. Journal of molecular neuroscience : MN. 2022-05-11. PMID:35543800. |
in addition, lower reactivity (ira) for glial fibrillary acidic protein (gfap) as an index of astrocyte activity was observed and loss of ca1 pyramidal neurons was attenuated following sinomenine treatment. |
2022-05-11 |
2023-08-13 |
Not clear |
| Ai-Wen Yang, Ni-Hsuan Lin, Ting-Hung Yeh, Natasha Snider, Ming-Der Pern. Effects of Alexander disease-associated mutations on the assembly and organization of GFAP intermediate filaments. Molecular biology of the cell. 2022-05-05. PMID:35511821. |
alexander disease is a primary genetic disorder of astrocyte caused by dominant mutations in the gene encoding gfap. |
2022-05-05 |
2023-08-13 |
Not clear |
| Tianfeng Huang, Yinggang Xiao, Yang Zhang, Cunjin Wang, Xiaoping Chen, Yong Li, Yali Ge, Ju Ga. miR-223 ameliorates thalamus hemorrhage-induced central poststroke pain via targeting NLRP3 in a mouse model. Experimental and therapeutic medicine. vol 23. issue 5. 2022-05-02. PMID:35493427. |
the expression level of gfap was detected to determine astrocyte activation. |
2022-05-02 |
2023-08-13 |
mouse |
| Kazuki Hatayama, Sydney Riddick, Fares Awa, Xiaodi Chen, Daniela Virgintino, Barbara S Stonestree. Time Course of Changes in the Neurovascular Unit after Hypoxic-Ischemic Injury in Neonatal Rats. International journal of molecular sciences. vol 23. issue 8. 2022-04-23. PMID:35456999. |
the right hi and left hypoxic alone sides of the brains were examined by quantitative immunohistochemistry for vascular density (laminin), pericyte vascular coverage (pdgfrβ), astrocyte vascular coverage (gfap), and claudin-5 expression in the microvasculature of the cerebral cortex, white matter, and hippocampus. |
2022-04-23 |
2023-08-13 |
rat |
| Chloé Morel, Armelle Christophe, Katy Maguin-Gaté, Justine Paoli, Jonathan David Turner, Henri Schroeder, Nathalie Grov. Head-to-Head Study of Developmental Neurotoxicity and Resultant Phenotype in Rats: α-Hexabromocyclododecane versus Valproic Acid, a Recognized Model of Reference for Autism Spectrum Disorders. Toxics. vol 10. issue 4. 2022-04-21. PMID:35448441. |
at the same age, α-hbcdd pointed out significant overexpression of cortical markers of synaptic plasticity while both treated groups showed a significant under expression of astrocyte proteins (s100-β and gfap). |
2022-04-21 |
2023-08-13 |
rat |
| Yonggang Xie, Zhen Li, Hongyu Xu, Jiahai Ma, Tao Li, Cunxian Shi, Jin Ji. Downregulation of Sp1 Inhibits the Expression of HDAC1/SOX10 to Alleviate Neuropathic Pain-like Behaviors after Spinal Nerve Ligation in Mice. ACS chemical neuroscience. 2022-04-14. PMID:35420781. |
immunofluorescence was performed to determine sp1, hdac1, and sox10 in the spinal dorsal horn neurons as well as the neuronal marker (neun), microglial marker (iba-1), and astrocyte marker (gfap). |
2022-04-14 |
2023-08-13 |
mouse |
| Jae-Won Hyun, Yeseul Kim, Ki Hoon Kim, Su-Hyun Kim, Mads Nikolaj Olesen, Nasrin Asgari, Sasitorn Siritho, Friedemann Paul, Ho Jin Ki. CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage. Journal of neuroinflammation. vol 19. issue 1. 2022-04-13. PMID:35413922. |
csf gfap levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage. |
2022-04-13 |
2023-08-13 |
Not clear |
| Ciro De Luca, Assunta Virtuoso, Sohaib Ali Korai, Raffaella Cirillo, Francesca Gargano, Michele Papa, Giovanni Cirill. Altered Spinal Homeostasis and Maladaptive Plasticity in GFAP Null Mice Following Peripheral Nerve Injury. Cells. vol 11. issue 7. 2022-04-12. PMID:35406788. |
glial acidic fibrillary protein (gfap), a major protein constituent of astrocyte intermediate filaments (ifs), is the hallmark of the reactive astrocytes, has pleiotropic functions and is significantly upregulated in the spinal cord after nerve injury. |
2022-04-12 |
2023-08-13 |
mouse |