Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
J P O'Callaghan, D B Miller, J F Reinhar. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced damage of striatal dopaminergic fibers attenuates subsequent astrocyte response to MPTP. Neuroscience letters. vol 117. issue 1-2. 1991-04-01. PMID:1981254. |
the astrocyte (gfap) response declined to baseline three weeks after administration of mptp. |
1991-04-01 |
2023-08-11 |
mouse |
E Bongcam-Rudloff, M Nistér, C Betsholtz, J L Wang, G Stenman, K Huebner, C M Croce, B Westermar. Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes. Cancer research. vol 51. issue 5. 1991-03-29. PMID:1847665. |
glial fibrillary acidic protein (gfap) is a constituent of intermediate filaments of glial cells of the astrocyte lineage. |
1991-03-29 |
2023-08-11 |
human |
C Agresti, F Aloisi, G Lev. Heterotypic and homotypic cellular interactions influencing the growth and differentiation of bipotential oligodendrocyte-type-2 astrocyte progenitors in culture. Developmental biology. vol 144. issue 1. 1991-03-27. PMID:1995394. |
cell populations highly enriched in oligodendrocyte-type-2 astrocyte (o-2a) progenitors (so defined by their ability to bind the monoclonal antibodies lb1 and o4, and by the lack of expression of the differentiated glial markers galactocerebroside and glial fibrillary acidic protein (gfap) were obtained from rat mixed cortical glial cultures. |
1991-03-27 |
2023-08-11 |
rat |
C K Petito, S Morgello, J C Felix, M L Lesse. The two patterns of reactive astrocytosis in postischemic rat brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 10. issue 6. 1990-11-20. PMID:2211878. |
in addition, the results show that astrocyte expression of vimentin is more specific than gfap in identifying regions of permanent ischemic injury during the early postischemic period. |
1990-11-20 |
2023-08-11 |
rat |
J P O'Callaghan, D B Miller, J F Reinhar. Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain research. vol 521. issue 1-2. 1990-11-09. PMID:1976416. |
radioimmunoassay of the astrocyte protein, glial fibrillary acidic protein (gfap), was used to quantify the astrocyte reaction to mptp. |
1990-11-09 |
2023-08-11 |
mouse |
J P O'Callaghan, D B Miller, J F Reinhar. Characterization of the origins of astrocyte response to injury using the dopaminergic neurotoxicant, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Brain research. vol 521. issue 1-2. 1990-11-09. PMID:1976416. |
together, these findings suggest that diffusible factors derived from damaged dopaminergic neurons initiate the astrocyte response to mptp and that large increases in gfap can be induced without the participation of serum-derived growth factor. |
1990-11-09 |
2023-08-11 |
mouse |
M D Norenberg, J T Neary, L O Norenberg, M McCarth. Ammonia induced decrease in glial fibrillary acidic protein in cultured astrocytes. Journal of neuropathology and experimental neurology. vol 49. issue 4. 1990-08-06. PMID:2163437. |
in view of the important role of ammonia in the pathogenesis of he, we carried out immunocytochemical and enzyme-linked immunosorbent assay (elisa) studies on the effect of ammonium chloride (10 mm) on gfap content in primary astrocyte cultures. |
1990-08-06 |
2023-08-11 |
human |
M Brenner, K Lampel, Y Nakatani, J Mill, C Banner, K Mearow, M Dohadwala, R Lipsky, E Frees. Characterization of human cDNA and genomic clones for glial fibrillary acidic protein. Brain research. Molecular brain research. vol 7. issue 4. 1990-07-31. PMID:2163003. |
both a partial cdna clone and a complete genomic clone have been isolated for human gfa, the gene encoding the major component of astrocyte intermediate filaments, glial fibrillary acidic protein (gfap). |
1990-07-31 |
2023-08-11 |
mouse |
P R Laming, S L Cosby, J K O'Neil. Seizures in the Mongolian gerbil are related to a deficiency in cerebral glutamine synthetase. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 94. issue 2. 1990-06-07. PMID:2576778. |
gfap immunohistochemistry was used on forebrain sections to assay astrocyte density. |
1990-06-07 |
2023-08-11 |
Not clear |
R P Skof. Gliogenesis in rat optic nerve: astrocytes are generated in a single wave before oligodendrocytes. Developmental biology. vol 139. issue 1. 1990-05-25. PMID:2328833. |
the question of whether astrocytes in the rat optic nerve arise directly from division of an undifferentiated, common progenitor cell or from a cell committed to the astrocyte lineage was addressed by combining thymidine autoradiography with gfap immunocytochemistry. |
1990-05-25 |
2023-08-11 |
rat |
B L Maria, D Wong, V I Kalnin. Dibutyryl cyclic AMP induces vimentin and GFAP expression in cultured medulloblastoma cells. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 17. issue 1. 1990-04-13. PMID:2155693. |
astrocyte progenitor cells from the mouse neopallium however express another if protein, vimentin, before they acquire gfap in vivo and in vitro. |
1990-04-13 |
2023-08-11 |
mouse |
B L Maria, D Wong, V I Kalnin. Dibutyryl cyclic AMP induces vimentin and GFAP expression in cultured medulloblastoma cells. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 17. issue 1. 1990-04-13. PMID:2155693. |
western immunoblotting showed an increase in vimentin which reached maximal values within 24 h followed by an increase in gfap which reached maximal values at 72 h. the increase in vimentin followed by that of gfap in cultured medulloblastoma cells has not previously been reported and suggests that most astrocyte progenitors which are derived from medulloblastoma and cultured in vitro may be at a developmental stage which corresponds to the proastroblast stage in the developing mouse brain. |
1990-04-13 |
2023-08-11 |
mouse |
S P Cass, H G Goshgaria. Increased glial fibrillary acidic protein immunoreactivity in astrocytes within the lateral vestibular nucleus of the cat following labyrinthectomy and vestibular neurectomy. The Annals of otology, rhinology, and laryngology. vol 99. issue 3 Pt 1. 1990-04-10. PMID:2178543. |
the lateral vestibular nucleus (lvn) and vestibular nerve root entry zone on both sides of the brain stem were examined 24 hours, 3 days, and 8 weeks after operation by use of an immunochemical astrocyte marker, glial fibrillary acidic protein (gfap). |
1990-04-10 |
2023-08-11 |
cat |
D Pekovic, C S Raine, U Traugot. Increase in anti-astrocyte antibodies in the serum of guinea pigs during active stages of experimental autoimmune encephalomyelitis. Journal of neuroimmunology. vol 26. issue 3. 1990-04-05. PMID:1689746. |
by immunoblotting, astrocyte staining was shown to be due to the presence of antiglial fibrillary acidic protein (gfap) antibodies. |
1990-04-05 |
2023-08-11 |
mouse |
M McCarthy, M D Norenberg, L O Norenberg, R D Di. Herpes simplex virus type 1 infection of rat astrocytes in primary culture: effects of dibutyryl cyclic AMP. Journal of neuropathology and experimental neurology. vol 49. issue 1. 1990-02-26. PMID:2153759. |
infection with hsv-1 did not stimulate synthesis of glial fibrillary acidic protein (gfap) or alter the general organization of the intermediate (glial) filaments in astrocyte cultures. |
1990-02-26 |
2023-08-11 |
human |
S S Shehab, C A Stafford, S N Nona, J R Cronly-Dillo. Anti-goldfish glial fibrillary acidic protein (GFAP) recognises astrocytes from rat CNS. Brain research. vol 504. issue 2. 1990-02-06. PMID:2598035. |
a polyclonal antibody to goldfish gfap recognises, immunohistochemically, astrocyte populations in rat brain, spinal cord and optic nerve. |
1990-02-06 |
2023-08-11 |
rat |
A Bettica, A B Johnso. Ultrastructural immunogold labeling of glial filaments in osmicated and unosmicated epoxy-embedded tissue. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 38. issue 1. 1990-02-01. PMID:2152935. |
in this study, glial fibrillary acidic protein (gfap), the major protein of astrocyte intermediate filaments, was localized with a post-embedding immunogold method, using both unosmicated and osmicated material embedded in epoxy resin. |
1990-02-01 |
2023-08-11 |
Not clear |
B L Maria, P A Steck, W K Yung, A Milici, J M Bruner, S Pathak, F F Becke. The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen. Journal of neuro-oncology. vol 7. issue 4. 1990-01-08. PMID:2555453. |
the assessment of astrocytic differentiation in medulloblastoma rests largely on the detection in malignant cells of glial fibrillary acidic protein (gfap), a marker present in the later stages of normal astrocyte differentiation. |
1990-01-08 |
2023-08-11 |
Not clear |
B L Maria, P A Steck, W K Yung, A Milici, J M Bruner, S Pathak, F F Becke. The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen. Journal of neuro-oncology. vol 7. issue 4. 1990-01-08. PMID:2555453. |
it is still not known whether cells that do not contain gfap in medulloblastomas with astrocytic differentiation correspond to highly proliferative astrocyte progenitors in maturation arrest at earlier stages of differentiation. |
1990-01-08 |
2023-08-11 |
Not clear |
B L Maria, P A Steck, W K Yung, A Milici, J M Bruner, S Pathak, F F Becke. The modulation of astrocytic differentiation in cells derived from a medulloblastoma surgical specimen. Journal of neuro-oncology. vol 7. issue 4. 1990-01-08. PMID:2555453. |
cells in culture and in medulloblastoma tumor specimens which do not contain gfap may represent astrocyte progenitors in maturation arrest. |
1990-01-08 |
2023-08-11 |
Not clear |