| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Regunathan, D L Feinstein, D J Rei. Expression of non-adrenergic imidazoline sites in rat cerebral cortical astrocytes. Journal of neuroscience research. vol 34. issue 6. 1993-07-23. PMID:8315666. |
we conclude that (a) the non-adrenergic imidazoline binding sites are expressed in astrocytes but not in neurons in rat cerebral cortex and (b) these "receptors" may influence astrocyte physiology by regulating the levels of gfap. |
1993-07-23 |
2023-08-12 |
rat |
| J Llorens, K M Crofton, J P O'Callagha. Administration of 3,3'-iminodipropionitrile to the rat results in region-dependent damage to the central nervous system at levels above the brain stem. The Journal of pharmacology and experimental therapeutics. vol 265. issue 3. 1993-07-14. PMID:8510024. |
an immunoassay for the astrocyte intermediate filament protein, glial fibrillary acidic protein (gfap), was used to quantify gliosis. |
1993-07-14 |
2023-08-12 |
rat |
| J Sutin, R Griffit. Beta-adrenergic receptor blockade suppresses glial scar formation. Experimental neurology. vol 120. issue 2. 1993-06-17. PMID:8387932. |
astrocyte hypertrophy was evaluated by optical density measurements of immunolabeled gfap. |
1993-06-17 |
2023-08-12 |
rat |
| J Sutin, R Griffit. Beta-adrenergic receptor blockade suppresses glial scar formation. Experimental neurology. vol 120. issue 2. 1993-06-17. PMID:8387932. |
when l-propranolol is continuously infused from a subcutaneously implanted osmotic pump at a concentration calculated to produce a free plasma level of 4.4 nm, the gfap increase is only 3.2 +/- 3%, reflecting a 73% reduction in astrocyte hypertrophy (p < 0.001). |
1993-06-17 |
2023-08-12 |
rat |
| M Rubio, G Bodega, I Suárez, R M Villalba, B Fernánde. Effects of experimentally induced hyperammonemia on glial fibrillary acidic protein (GFAP) in the rhombencephalon of goldfish (Carassius auratus L.). Neuroscience research. vol 16. issue 1. 1993-06-02. PMID:8387165. |
hyperammonemia mostly affected gfap in the astrocyte processes associated with cholinergic pathways. |
1993-06-02 |
2023-08-12 |
Not clear |
| C R Goodlett, J T Leo, J P O'Callaghan, J C Mahoney, J R Wes. Transient cortical astrogliosis induced by alcohol exposure during the neonatal brain growth spurt in rats. Brain research. Developmental brain research. vol 72. issue 1. 1993-04-19. PMID:8453767. |
the astrocyte response to central nervous system injury induced by neonatal alcohol exposure was evaluated using radioimmunoassay and immunocytochemistry of glial fibrillary acidic protein (gfap). |
1993-04-19 |
2023-08-12 |
rat |
| J M Ordy, T M Wengenack, P Bialobok, P D Coleman, P Rodier, R B Baggs, W P Dunlap, B Kate. Selective vulnerability and early progression of hippocampal CA1 pyramidal cell degeneration and GFAP-positive astrocyte reactivity in the rat four-vessel occlusion model of transient global ischemia. Experimental neurology. vol 119. issue 1. 1993-03-15. PMID:8432346. |
the goals of this study were to: (1) develop specific criteria for 4-vo ischemia to ensure selective, bilaterally symmetrical ca1 pyramidal cell damage, (2) examine the effects of 15 min of ischemia on concomitant ca1 cell necrosis and presence of remaining and/or "viable" neurons postischemia, (3) compare 15 and 30 min of ischemia on differential vulnerability of ca1-ca3 subfields, and (4) evaluate the effects of 15 min of ischemia on ca1 pyramidal cell necrosis and glial fibrillary acidic protein (gfap)-positive astrocyte reactivity in ca1. |
1993-03-15 |
2023-08-12 |
rat |
| M S Bailey, M T Shiple. Astrocyte subtypes in the rat olfactory bulb: morphological heterogeneity and differential laminar distribution. The Journal of comparative neurology. vol 328. issue 4. 1993-03-09. PMID:8429132. |
using a known immunohistochemical marker for astrocytes, glial fibrillary acidic protein (gfap), and the classic gold sublimate method, we identified six astrocyte subtypes based on their morphology and distribution: (1) unipolar, (2) irregular, (3) wedge-shape, (4) circular, (5) semicircular, and (6) elongate. |
1993-03-09 |
2023-08-12 |
rat |
| M S Bailey, M T Shiple. Astrocyte subtypes in the rat olfactory bulb: morphological heterogeneity and differential laminar distribution. The Journal of comparative neurology. vol 328. issue 4. 1993-03-09. PMID:8429132. |
the distribution and patterns of astrocyte processes and the density of gfap immunoreactivity are distinctive for each of the layers of the olfactory bulb. |
1993-03-09 |
2023-08-12 |
rat |
| S Wang, G J Lees, E Bock, A Hamberger, K G Hagli. Biphasic changes in NCAM level after an NMDA lesion to the hippocampal formation: a quantitative dot-immunobinding assay. Journal of neuroscience research. vol 33. issue 4. 1993-02-12. PMID:1484396. |
the time course of changes differed from that of the glial fibrillary acidic protein (gfap), a marker for reactive astroglial cell, but was similar to that for the markers of sprouting neurites, i.e., low (l) and high (h) molecular weight subunits of the neurofilament polypeptides. |
1993-02-12 |
2023-08-11 |
rat |
| K Ohtani, A Suzumura, M Sawada, T Marunouchi, I Nakashima, A Takahash. Establishment of mouse oligodendrocyte/type-2 astrocyte lineage cell line by transfection with origin-defective simian virus 40 DNA. Cell structure and function. vol 17. issue 5. 1993-02-01. PMID:1335367. |
this cell line, designated os3, has morphological similarity to type-2 astrocyte and expresses an astrocyte-specific marker, glial fibrillary acidic protein (gfap), when cultured in the presence of 10% calf serum (cs). |
1993-02-01 |
2023-08-11 |
mouse |
| K Janeczk. A comparison of the proliferative activity of astrocytes and astrocyte-like cells expressing vimentin in the injured mouse cerebral hemisphere. Folia histochemica et cytobiologica. vol 30. issue 1. 1992-12-30. PMID:1446778. |
those facts were considered as an evidence against the hypothesis that a reactive astrocyte division induces a two-stage increase in the cytoskeletal proteins level with the elevated synthesis of vimentin preceding that of gfap. |
1992-12-30 |
2023-08-11 |
mouse |
| T Miyake, M Okada, T Kitamur. Reactive proliferation of astrocytes studied by immunohistochemistry for proliferating cell nuclear antigen. Brain research. vol 590. issue 1-2. 1992-12-15. PMID:1358404. |
astrocyte proliferation in the stab-wounded cerebral cortex of mice was studied using double immunohistochemistry for proliferating cell nuclear antigen (pcna) and glial fibrillary acidic protein (gfap). |
1992-12-15 |
2023-08-11 |
mouse |
| G R Post, G Dawso. Characterization of a cell line derived from a human oligodendroglioma. Molecular and chemical neuropathology. vol 16. issue 3. 1992-12-04. PMID:1329795. |
hog cells did not express the characteristic astrocyte markers glial fibrillary acidic protein (gfap) or significant glutamine synthetase (gs) activity. |
1992-12-04 |
2023-08-11 |
human |
| E J Anderson, D McFarland, H K Kimelber. Serotonin uptake by astrocytes in situ. Glia. vol 6. issue 2. 1992-11-06. PMID:1398897. |
also, as with astrocyte cultures, only some of the gfap(+) astrocytes in situ showed localization of radioactivity, supporting the concept of intraregional heterogeneity of astrocyte functions. |
1992-11-06 |
2023-08-11 |
rat |
| P A Cancilla, J Bready, J Berliner, H Sharifi-Nia, A W Toga, E M Santori, S Scully, J deVelli. Expression of mRNA for glial fibrillary acidic protein after experimental cerebral injury. Journal of neuropathology and experimental neurology. vol 51. issue 5. 1992-10-06. PMID:1381417. |
thus, there is a rapid response of the astrocyte to injury with increased mrna expression that is followed by expression of gfap immunoreactivity. |
1992-10-06 |
2023-08-11 |
mouse |
| R H Amundson, S K Goderie, H K Kimelber. Uptake of [3H]serotonin and [3H]glutamate by primary astrocyte cultures. II. Differences in cultures prepared from different brain regions. Glia. vol 6. issue 1. 1992-09-30. PMID:1355075. |
glial fibrillary acidic protein (gfap) immunocytochemistry was used to confirm the astrocyte composition of the cultures. |
1992-09-30 |
2023-08-11 |
rat |
| B Pfeiffer, R Meyermann, B Hamprech. Immunohistochemical co-localization of glycogen phosphorylase with the astroglial markers glial fibrillary acidic protein and S-100 protein in rat brain sections. Histochemistry. vol 97. issue 5. 1992-09-14. PMID:1500296. |
immunofluorescence double-labelling and immunoenzyme double-staining methods were used to examine the location of glycogen phosphorylase brain isozyme with the astrocyte markers glial fibrillary acidic protein (gfap) and s-100 protein in formaldehyde-fixed, paraffin-embedded slices from adult rat brain. |
1992-09-14 |
2023-08-11 |
rat |
| D L Feinstein, G A Weinmaster, R J Milne. Isolation of cDNA clones encoding rat glial fibrillary acidic protein: expression in astrocytes and in Schwann cells. Journal of neuroscience research. vol 32. issue 1. 1992-08-18. PMID:1629938. |
to examine possible structural differences between cns and pns gfap, we have isolated cdna clones for rat gfap from both cultured astrocyte and schwann cell libraries. |
1992-08-18 |
2023-08-11 |
rat |
| J L Ridet, J Perre, J F Fonci. [The transition zone of the central nervous system-peripheral nervous system of the adult rat; ultrastructural and immunocytochemical studies: a new function of the astroglia?]. Journal fur Hirnforschung. vol 32. issue 6. 1992-08-18. PMID:1726542. |
the cns glial expansion shows an important gfap immunoreactivity with intimate association between astrocyte processes and myelinated axons. |
1992-08-18 |
2023-08-11 |
rat |