| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiuxiu Fu, Tingyu Zong, Panyu Yang, Lin Li, Shizhong Wang, Zhibin Wang, Min Li, Xiaolu Li, Yulin Zou, Ying Zhang, Lynn Htet Htet Aung, Yanyan Yang, Tao Y. Nicotine: Regulatory roles and mechanisms in atherosclerosis progression. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 151. 2021-09-14. PMID:33774093. |
nicotine, a selective cholinergic agonist, accelerates the formation of atherosclerosis by stimulating nicotinic acetylcholine receptors (nachrs) located in neuronal and non-neuronal tissues. |
2021-09-14 |
2023-08-13 |
Not clear |
| Lisa R Goldberg, Dana Zeid, Munir Gunes Kutlu, Robert D Cole, Valeria Lallai, Aswathy Sebastian, Istvan Albert, Christie D Fowler, Vinay Parikh, Thomas J Goul. Paternal nicotine enhances fear memory, reduces nicotine administration, and alters hippocampal genetic and neural function in offspring. Addiction biology. vol 26. issue 1. 2021-09-09. PMID:31782218. |
we tested the effects of chronic paternal nicotine exposure in c57bl6/j mice on fear conditioning in f1 and f2 offspring, as well as conditioned fear extinction and spontaneous recovery, nicotine self-administration, hippocampal cholinergic functioning, rna expression, and dna methylation in f1 offspring. |
2021-09-09 |
2023-08-13 |
mouse |
| Lisa R Goldberg, Dana Zeid, Munir Gunes Kutlu, Robert D Cole, Valeria Lallai, Aswathy Sebastian, Istvan Albert, Christie D Fowler, Vinay Parikh, Thomas J Goul. Paternal nicotine enhances fear memory, reduces nicotine administration, and alters hippocampal genetic and neural function in offspring. Addiction biology. vol 26. issue 1. 2021-09-09. PMID:31782218. |
these behavioral phenotypes were coupled with altered response to nicotine, upregulated hippocampal nicotinic acetylcholine receptor binding, reduced evoked hippocampal cholinergic currents, and altered methylation and expression of hippocampal genes related to neural development and plasticity. |
2021-09-09 |
2023-08-13 |
mouse |
| Sakura Nakauchi, Hailing Su, Ivan Trang, Katumi Sumikaw. Long-term effects of early postnatal nicotine exposure on cholinergic function in the mouse hippocampal CA1 region. Neurobiology of learning and memory. vol 181. 2021-08-20. PMID:33895349. |
long-term effects of early postnatal nicotine exposure on cholinergic function in the mouse hippocampal ca1 region. |
2021-08-20 |
2023-08-13 |
mouse |
| Sakura Nakauchi, Hailing Su, Ivan Trang, Katumi Sumikaw. Long-term effects of early postnatal nicotine exposure on cholinergic function in the mouse hippocampal CA1 region. Neurobiology of learning and memory. vol 181. 2021-08-20. PMID:33895349. |
given that hippocampal cholinergic systems modulate memory and rapid development of hippocampal cholinergic systems occurs during nicotine exposure, here we investigated its impacts on cholinergic function. |
2021-08-20 |
2023-08-13 |
mouse |
| Yousef Tizabi, Bruk Getachew, Michael Aschne. Novel Pharmacotherapies in Parkinson's Disease. Neurotoxicity research. vol 39. issue 4. 2021-07-13. PMID:34003454. |
specifically, the focus is on nicotine and nicotinic cholinergic system, as well as butyrate, a short chain fatty acid (scfa), and fatty acid receptors. |
2021-07-13 |
2023-08-13 |
Not clear |
| Martin A Fuentes-Cano, Dulce J Bustamante-Valdez, Pilar Durá. Perinatal exposure to nicotine disrupts circadian locomotor and learning efficiency rhythms in juvenile mice. Brain structure & function. vol 225. issue 7. 2021-07-06. PMID:32789697. |
nicotine, as an alkaloid, alters the reward system acting as acetylcholine (ach) agonist on nicotinic cholinergic receptors (nachrs). |
2021-07-06 |
2023-08-13 |
mouse |
| Xiao-Tao Jin, Brenton R Tucker, Ryan M Drena. Nicotine Self-Administration Induces Plastic Changes to Nicotinic Receptors in Medial Habenula. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32675176. |
our study demonstrates nachr functional enhancement by nicotine sa, confirming that volitional nicotine intake sensitizes cholinergic systems in the brain. |
2021-06-18 |
2023-08-13 |
rat |
| Jonna M Leyrer-Jackson, Michael Holter, Paula F Overby, Jason M Newbern, Michael D Scofield, M Foster Olive, Cassandra D Gipso. Accumbens Cholinergic Interneurons Mediate Cue-Induced Nicotine Seeking and Associated Glutamatergic Plasticity. eNeuro. vol 8. issue 1. 2021-06-18. PMID:33239269. |
accumbens cholinergic interneurons mediate cue-induced nicotine seeking and associated glutamatergic plasticity. |
2021-06-18 |
2023-08-13 |
rat |
| Alice Courties, Jeremy Boussier, Jérôme Hadjadj, Nader Yatim, Laura Barnabei, Hélène Péré, David Veyer, Solen Kernéis, Nicolas Carlier, Frédéric Pène, Frédéric Rieux-Laucat, Bruno Charbit, Vincent Bondet, Darragh Duffy, Francis Berenbaum, Benjamin Terrier, Jérémie Sella. Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients. Scientific reports. vol 11. issue 1. 2021-06-18. PMID:34088975. |
expression of this duplicate might be considered before targeting the cholinergic system in covid-19 with nicotine. |
2021-06-18 |
2023-08-13 |
Not clear |
| Stefan Ahrens, Joana Laux, Christina Müller, Christiane M Thie. Increased dopamine availability magnifies nicotine effects on cognitive control: A pilot study. Journal of psychopharmacology (Oxford, England). vol 34. issue 5. 2021-06-17. PMID:32133910. |
we aimed to test the hypothesis that the effect of the cholinergic agonist nicotine on cognitive control depends on baseline dopamine levels. |
2021-06-17 |
2023-08-13 |
Not clear |
| Stefan Ahrens, Christiane M Thie. Effects of Nicotine on Task Switching and Distraction in Non-smokers. An fMRI Study. Neuroscience. vol 444. 2021-05-14. PMID:32717295. |
we aimed to test how the cholinergic agonist nicotine modulates this balance and used an ongoing visual task including switch and distractor trials to gauge cognitive flexibility and stability respectively. |
2021-05-14 |
2023-08-13 |
Not clear |
| Alex G Gauthier, Mosi Lin, Jiaqi Wu, Thomas P Kennedy, Lee-Anne Daley, Charles R Ashby, Lin L Mantel. From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19? Journal of immunotoxicology. vol 18. issue 1. 2021-04-30. PMID:33860730. |
from nicotine to the cholinergic anti-inflammatory reflex - can nicotine alleviate the dysregulated inflammation in covid-19? |
2021-04-30 |
2023-08-13 |
Not clear |
| Alex G Gauthier, Mosi Lin, Jiaqi Wu, Thomas P Kennedy, Lee-Anne Daley, Charles R Ashby, Lin L Mantel. From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19? Journal of immunotoxicology. vol 18. issue 1. 2021-04-30. PMID:33860730. |
nicotine can activate the cholinergic anti-inflammatory reflex, which attenuates the up-regulation and the excessive release of pro-inflammatory cytokines/chemokines. |
2021-04-30 |
2023-08-13 |
Not clear |
| Alex G Gauthier, Mosi Lin, Jiaqi Wu, Thomas P Kennedy, Lee-Anne Daley, Charles R Ashby, Lin L Mantel. From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the dysregulated inflammation in COVID-19? Journal of immunotoxicology. vol 18. issue 1. 2021-04-30. PMID:33860730. |
therefore, we hypothesize that low molecular weight compounds that activate the cholinergic anti-inflammatory reflex, such as nicotine or gts-21, may represent a potential therapeutic approach to attenuate the dysregulated inflammatory responses in patients with severe covid-19. |
2021-04-30 |
2023-08-13 |
Not clear |
| Yanping Zhang, Alec Sevilla, Robert Weller, Shuju Wang, Melvin C Gitlin, Keith A Candiott. The role of α7-nicotinic acetylcholine receptor in a rat model of chronic nicotine-induced mechanical hypersensitivity. Neuroscience letters. vol 743. 2021-04-29. PMID:33352289. |
nicotine is the main component of tobacco and acts as an agonist for nicotinic cholinergic receptors (nachrs) in the nervous system. |
2021-04-29 |
2023-08-13 |
rat |
| Yasmine Sherafat, Malia Bautista, Christie D Fowle. Multidimensional Intersection of Nicotine, Gene Expression, and Behavior. Frontiers in behavioral neuroscience. vol 15. 2021-04-10. PMID:33828466. |
nicotine, the reinforcing component of tobacco and e-cigarettes, directly acts on the cholinergic system by targeting nicotinic acetylcholine receptors (nachrs) in the brain. |
2021-04-10 |
2023-08-13 |
Not clear |
| Tamara Stojanovic, Hannah Benes, Amena Awad, Daniel Bormann, Francisco J Monj. Nicotine abolishes memory-related synaptic strengthening and promotes synaptic depression in the neurogenic dentate gyrus of miR-132/212 knockout mice. Addiction biology. vol 26. issue 2. 2021-03-30. PMID:32293776. |
smoking is a predominant addictive behaviour associated with millions of deaths worldwide, and nicotine is a potent natural psychoactive agonist of cholinergic receptors, highly abundant in cigarettes. |
2021-03-30 |
2023-08-13 |
mouse |
| T Miladinovic, L A Manwell, E Raaphorst, S L Malecki, S A Rana, P E Malle. Effects of chronic nicotine exposure on Δ Pharmacology, biochemistry, and behavior. vol 194. 2021-03-30. PMID:32353393. |
effects of chronic nicotine exposure on Δ high rates of comorbid tobacco and cannabis use in adolescents and young adults may be related to functional interactions between the nicotinic cholinergic and cannabinoid systems in the brain during development. |
2021-03-30 |
2023-08-13 |
Not clear |
| George Lagoumintzis, Christos T Chasapis, Nikolaos Alexandris, Dimitrios Kouretas, Socrates Tzartos, Elias Eliopoulos, Konstantinos Farsalinos, Konstantinos Poula. Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 149. 2021-03-05. PMID:33503469. |
our findings provide further support to the hypothesis about the protective role of nicotine and other cholinergic agonists. |
2021-03-05 |
2023-08-13 |
human |