| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Dunbar, K Hitchcock, M Latimer, E L Rugg, N Ward, P Win. Excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. II. Examination of eating and drinking, rotation, and reaching and grasping following unilateral ibotenate or quinolinate lesions. Brain research. vol 589. issue 2. 1992-11-25. PMID:1356593. |
the purpose of the present experiment was, first, to make lesions of cholinergic neurons throughout the length of the pptg by infusing toxin at two different sites within it; and second, to examine simple motor activities in rats bearing either quinolinate or ibotenate lesions of the pptg, and contrast these with the deficits seen after 6-hydroxydopamine (6-ohda) induced lesions of mesostriatal dopamine (da)-containing neurons. |
1992-11-25 |
2023-08-11 |
rat |
| R A Lefebvr. The inhibitory effect of dopamine on cat gastric smooth muscle. The Journal of pharmacy and pharmacology. vol 44. issue 4. 1992-10-02. PMID:1355546. |
these results indicate that the inhibitory effect of dopamine in the cat gastric fundus is mainly due to interaction with postjunctional beta 2-adrenoceptors on the smooth muscle cells and with prejunctional alpha 2-adrenoceptors on the intramural cholinergic neurons. |
1992-10-02 |
2023-08-11 |
cat |
| M Mancini, A Ricci, F Ament. Age-related changes in sulfide-silver staining in the rat neostriatum: a quantitative histochemical study. Neurobiology of aging. vol 13. issue 4. 1992-09-21. PMID:1508301. |
the present results indicated that similar to the observations for a variety of neurochemical parameters of rat neostriatum such as local cerebral glucose utilization, cholinergic muscarinic receptors, and dopamine d-1 receptors, zinc-containing striatal terminal were primarily decreased between young and adult subjects but not between adult and aged animals. |
1992-09-21 |
2023-08-11 |
human |
| D L Bergstrom, C Kelle. Narcolepsy: pathogenesis and nursing care. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. vol 24. issue 3. 1992-09-08. PMID:1645038. |
current work implicates decreased production or utilization of norepinephrine, dopamine and serotonin in the brain, and excessively numerous or hypersensitive cholinergic receptors in the brain. |
1992-09-08 |
2023-08-11 |
Not clear |
| E Toth, H Sershen, A Hashim, E S Vizi, A Lajth. Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid. Neurochemical research. vol 17. issue 3. 1992-08-05. PMID:1352387. |
the cholinergic antagonists mecamylamine and atropine, the dopaminergic antagonists haloperidol and sulpiride, and the excitatory amino acid antagonist kynurenic acid all inhibited the nicotine-induced increase of extracellular dopamine in the striatum. |
1992-08-05 |
2023-08-11 |
rat |
| C E Tedford, G Crosby, L C Iorio, R E Chipki. Effect of SCH 39166, a novel dopamine D1 receptor antagonist, on [3H]acetylcholine release in rat striatal slices. European journal of pharmacology. vol 211. issue 2. 1992-07-28. PMID:1535318. |
the current studies investigated the pharmacological effects of sch 39166 on striatal cholinergic function in order to further characterize its dopamine d1 receptor selectivity and to address its eps liability. |
1992-07-28 |
2023-08-11 |
rat |
| C E Tedford, G Crosby, L C Iorio, R E Chipki. Effect of SCH 39166, a novel dopamine D1 receptor antagonist, on [3H]acetylcholine release in rat striatal slices. European journal of pharmacology. vol 211. issue 2. 1992-07-28. PMID:1535318. |
furthermore, selective dopamine d1 receptor antagonists, such as sch 39166, are ineffective in modulating striatal [3h]ach release, suggesting that striatal cholinergic hyperactivity and possibly eps will not be a consequence of dopamine d1 receptor blockade. |
1992-07-28 |
2023-08-11 |
rat |
| J R Bostwick, R Abbe, S H Appe. Phosphoethanolamine enhances high-affinity choline uptake and acetylcholine synthesis in dissociated cell cultures of the rat septal nucleus. Journal of neurochemistry. vol 59. issue 1. 1992-07-24. PMID:1613501. |
the effect of phosphoethanolamine was specific for cholinergic neurons, because treatment with this compound did not alter the kinetic constants for high-affinity neuronal uptake of gamma-aminobutyric acid or dopamine. |
1992-07-24 |
2023-08-11 |
rat |
| K Saka. Physiological properties and afferent connections of the locus coeruleus and adjacent tegmental neurons involved in the generation of paradoxical sleep in the cat. Progress in brain research. vol 88. 1992-06-16. PMID:1687620. |
this study demonstrates substantial and multiple afferent projections to the cat locus coeruleus arising from neurons containing acetylcholine, serotonin, norepinephrine, epinephrine, dopamine, histamine, and neuropeptides such as methionine, enkephaline and substance p. further, our studies reveal notable differences in afferent projection to the noradrenergic and cholinergic regions of the locus coeruleus. |
1992-06-16 |
2023-08-11 |
rat |
| J C Stoof, B Drukarch, P de Boer, B H Westerink, H J Groenewege. Regulation of the activity of striatal cholinergic neurons by dopamine. Neuroscience. vol 47. issue 4. 1992-06-05. PMID:1579210. |
regulation of the activity of striatal cholinergic neurons by dopamine. |
1992-06-05 |
2023-08-11 |
Not clear |
| T Ono, K Nakamura, M Fukuda, T Kobayash. Catecholamine and acetylcholine sensitivity of rat lateral hypothalamic neurons related to learning. Journal of neurophysiology. vol 67. issue 2. 1992-05-27. PMID:1569461. |
roles of the catecholaminergic and cholinergic systems in the lha were investigated by electrophoretic application of dopamine (da), norepinephrine (ne), acetylcholine (ach), and their antagonists [spiperone (spp), phenoxybenzamine (pbz), phentolamine, propranolol, and atropine (atr)]. |
1992-05-27 |
2023-08-11 |
rat |
| P De Boer, G Damsma, Q Schram, J C Stoof, J Zaagsma, B H Westerin. The effect of intrastriatal application of directly and indirectly acting dopamine agonists and antagonists on the in vivo release of acetylcholine measured by brain microdialysis. The importance of the post-surgery interval. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 2. 1992-05-22. PMID:1349159. |
this hyporesponsiveness of the striatal cholinergic interneurons to endogenous dopamine could not be attributed to dopamine d-1 receptor activation, since no effects on striatal acetylcholine release were found by intrastriatal infusions of the selective d-1 agonist cy 208-243 or the selective d-1 antagonist sch 23390. |
1992-05-22 |
2023-08-11 |
Not clear |
| J H Eubanks, M Altherr, C Wagner-McPherson, J D McPherson, J J Wasmuth, G A Evan. Localization of the D5 dopamine receptor gene to human chromosome 4p15.1-p15.3, centromeric to the Huntington's disease locus. Genomics. vol 12. issue 3. 1992-05-14. PMID:1532789. |
genes encoding g-protein-coupled receptors, including dopamine, serotonin, muscarinic cholinergic, and adrenergic receptors, play an important role in neurotransmission and may be involved in the pathophysiology of diseases such as alzheimer's disease, parkinson's disease, or huntington's disease (hd). |
1992-05-14 |
2023-08-11 |
human |
| J J Woodward, J Harm. Potentiation of N-methyl-D-aspartate-stimulated dopamine release from rat brain slices by aluminum fluoride and carbachol. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1532197. |
the mixed cholinergic agonist carbachol and the calcium ionophore a23187 mimicked the alf4- effect although the increase in nmda-stimulated dopamine release produced by these agents was less than that seen with alf4-. |
1992-04-17 |
2023-08-11 |
rat |
| H Hara, H Onodera, H Kato, K Kogur. Effects of aging on signal transmission and transduction systems in the gerbil brain: morphological and autoradiographic study. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1347408. |
autoradiography was used to map muscarinic cholinergic (labeled with [3h]quinuclidinyl benzilate), serotonin2 ([3h]spiperone), dopamine d2 ([3h]spiperone), adenosine a1 ([3h]cyclohexyladenosine), gabaa ([3h]muscimol), naloxone ([3h]naloxone), protein kinase c ([3h]phorbol 12,13-dibutyrate), adenylate cyclase ([3h]forskolin), cyclic amp ([3h]cyclic amp) and l-type ca2+ channels ([3h]pn200-110). |
1992-04-08 |
2023-08-11 |
Not clear |
| H Hara, H Onodera, H Kato, K Kogur. Effects of aging on signal transmission and transduction systems in the gerbil brain: morphological and autoradiographic study. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1347408. |
muscarinic cholinergic, serotonin2 and dopamine d2 receptors and adenylate cyclase were significantly decreased in the striatum. |
1992-04-08 |
2023-08-11 |
Not clear |
| V Dolezal, R Jackisch, G Hertting, C Allgaie. Activation of dopamine D1 receptors does not affect D2 receptor-mediated inhibition of acetylcholine release in rabbit striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 345. issue 1. 1992-04-02. PMID:1347152. |
it is concluded that the inhibition of acetylcholine release by dopamine is mediated exclusively via presynaptic dopamine d2 receptors and that the antagonistic effect of sch 23390 on the inhibition of acetylcholine release by quinpirole is due to its interaction with dopamine d2 rather than d1 receptors located on cholinergic nerve terminals. |
1992-04-02 |
2023-08-11 |
rabbit |
| H J Lee, L M Alcorn, M H Weile. Effects of various experimental manipulations on neostriatal acetylcholine and dopamine release. Neurochemical research. vol 16. issue 8. 1992-03-26. PMID:1787876. |
the dopamine endogenous to the slice preparation appeared to have little effect on the release of endogenous acetylcholine since manipulations that significantly altered dopamine release (depletion with 6-hydroxydopamine or uptake inhibition with nomifensine) had minimal effects on the cholinergic neurons. |
1992-03-26 |
2023-08-11 |
rat |
| H J Lee, L M Alcorn, M H Weile. Effects of various experimental manipulations on neostriatal acetylcholine and dopamine release. Neurochemical research. vol 16. issue 8. 1992-03-26. PMID:1787876. |
these studies indicate that within the neostriatal slices there is minimal influence of the endogenous dopamine on the cholinergic neurons, whereas the extracellular acetylcholine can influence dopamine release when its concentration is increased by inhibition of acetylcholinesterase. |
1992-03-26 |
2023-08-11 |
rat |
| G C Parker, E L Rugg, P Win. Cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones. Experimental brain research. vol 87. issue 3. 1992-03-13. PMID:1723691. |
cholinergic stimulation of substantia nigra: abolition of carbachol-induced eating by unilateral 6-hydroxydopamine lesion of nigrostriatal dopamine neurones. |
1992-03-13 |
2023-08-11 |
rat |