| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Guenaneche, R A Lefebvr. Influence of the DA2-receptor agonist quinpirole on the guinea pig ileum. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:1974639. |
in concentrations selective for dopamine receptors (10(-9)-10(-7) m), quinpirole did not influence cholinergic twitch responses induced by transmural stimulation at supramaximal voltage, but it concentration-dependently facilitated them in the concentration range 10(-6) to 10(-4) m; the potency of quinpirole was similar to that of metoclopramide (ed50 values, 6.0 x 10(-6) m and 2.2 x 10(-6) m, respectively). |
1990-09-17 |
2023-08-11 |
Not clear |
| A Dahlström, A Wigander, K Lundmark, C G Gottfries, P M Carvey, A McRa. Investigations on auto-antibodies in Alzheimer's and Parkinson's diseases, using defined neuronal cultures. Journal of neural transmission. Supplementum. vol 29. 1990-08-01. PMID:2358801. |
dopamine containing cell bodies were labelled by parkinsonian csf-igg, while cholinergic neurons, identified with a-ngf-receptor antibodies, were recognized by csf from ad-patients. |
1990-08-01 |
2023-08-11 |
rat |
| K Mueller, P M Kunk. The effects of amphetamine and pilocarpine on the release of ascorbic and uric acid in several rat brain areas. Pharmacology, biochemistry, and behavior. vol 35. issue 4. 1990-07-02. PMID:2345762. |
linear sweep voltammetry was used to investigate the effects of amphetamine (which enhances the release of dopamine) and/or pilocarpine (a cholinergic agonist) on the release of ascorbic acid and uric acid in brain areas differing in dopamine and acetylcholine concentrations. |
1990-07-02 |
2023-08-11 |
rat |
| A D Crocker, R W Russel. Pretreatment with an irreversible muscarinic agonist affects responses to apomorphine. Pharmacology, biochemistry, and behavior. vol 35. issue 3. 1990-06-18. PMID:2339142. |
the main aim of the present study was to investigate if responses to the direct dopamine agonist, apomorphine, could be modified by changes in the activity of cholinergic neurones. |
1990-06-18 |
2023-08-11 |
Not clear |
| S L Górniak, J Palermo-Neto, H de Souza-Spinos. Effects of a Palicourea marcgravii leaf extract on some dopamine-related behaviors of rats. Journal of ethnopharmacology. vol 28. issue 3. 1990-06-14. PMID:2335961. |
these results with the extract can be interpreted to be due to a direct blocking action for the extract on a mesostriatal dopamine receptor or to an indirect effect on dopamine pathways through central cholinergic activation. |
1990-06-14 |
2023-08-11 |
rat |
| J Wicken. Striatal dopamine in motor activation and reward-mediated learning: steps towards a unifying model. Journal of neural transmission. General section. vol 80. issue 1. 1990-04-09. PMID:2407269. |
the existence of separate populations of dopamine receptors, differentially modulating cholinergic and glutamatergic synapses, suggests a possible resolution to this paradox. |
1990-04-09 |
2023-08-11 |
Not clear |
| J Wicken. Striatal dopamine in motor activation and reward-mediated learning: steps towards a unifying model. Journal of neural transmission. General section. vol 80. issue 1. 1990-04-09. PMID:2407269. |
on the other hand, dopamine d2 receptors on cholinergic terminals may mediate indirect, inhibitory effects of dopamine on striatal neurons. |
1990-04-09 |
2023-08-11 |
Not clear |
| S Yamada, S Nishi, H Kojima, H Yokoo, T Tsutsumi, K Inanag. Involvement of the cholinergic system in haloperidol-induced release of dopamine from slices of striatum in the rat. Neuropharmacology. vol 29. issue 1. 1990-03-19. PMID:2304616. |
involvement of the cholinergic system in haloperidol-induced release of dopamine from slices of striatum in the rat. |
1990-03-19 |
2023-08-11 |
rat |
| S Yamada, S Nishi, H Kojima, H Yokoo, T Tsutsumi, K Inanag. Involvement of the cholinergic system in haloperidol-induced release of dopamine from slices of striatum in the rat. Neuropharmacology. vol 29. issue 1. 1990-03-19. PMID:2304616. |
the effects of cholinergic and anticholinergic drugs on spontaneous or haloperidol-induced release of dopamine (da) were studied in vitro. |
1990-03-19 |
2023-08-11 |
rat |
| A Ghahary, J Vriend, K W Chen. Modification of the indolamine content in neuroblastoma x glioma hybrid NG108-15 cells upon induced differentiation. Cellular and molecular neurobiology. vol 9. issue 3. 1990-03-01. PMID:2482134. |
the clonal ng108-15 cell line is also catecholaminergic, in addition to cholinergic and serotonergic; and a shift of neurotransmitter pattern from serotonin to dopamine production occurs during morphological differentiation. |
1990-03-01 |
2023-08-11 |
Not clear |
| F Bordi, E Melle. Enhanced behavioral stereotypies elicited by intrastriatal injection D1 and D2 dopamine agonists in intact rats. Brain research. vol 504. issue 2. 1990-02-06. PMID:2574622. |
five components of behavior elicited by dopamine (da) agonists (locomotor hyperactivity, sniffing, oral activity, grooming and paw nibbling) were evaluated after bilateral infusion of the selective d1 agonist fenoldopam (skf 82526; 2.5-10 micrograms), the selective d2 agonist quinpirole (ly 171555; 5-40 micrograms) and the muscarinic cholinergic antagonist scopolamine (5-20 micrograms) into the ventral striatum of awake, unrestrained rats. |
1990-02-06 |
2023-08-11 |
rat |
| B Amole, N Sharpless, M Wittner, H B Tanowit. Neurochemical measurements in the brains of mice infected with Trypanosoma brucei brucei (TREU 667). Annals of tropical medicine and parasitology. vol 83. issue 3. 1990-01-29. PMID:2481428. |
to study the possible neurochemical basis of these abnormalities, we measured brain acetylcholine receptor numbers, activities of the cholinergic enzymes, choline acetyltransferase (cat), and acetylcholinesterase (ache), and regional concentrations of the monoamines, dopamine (da), serotonin (5-ht), and norepinephrine (ne), and their acid metabolites, homovanillic acid (hva), 3,4-dihydroxyphenylacetic acid (dopac), and 5-hydroxyindoleacetic acid (5-hiaa) in mice infected with t. b. brucei. |
1990-01-29 |
2023-08-11 |
mouse |
| M L Kemel, M Desban, J Glowinski, C Gauch. Distinct presynaptic control of dopamine release in striosomal and matrix areas of the cat caudate nucleus. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 22. 1989-12-21. PMID:2813435. |
by use of a sensitive in vitro microsuperfusion method, the cholinergic prsynaptic control of dopamine release was investigated in a prominent striosome (areas poor in acetylcholinesterase activity) located within the core of cat caudate nucleus and also in adjacent matrix area. |
1989-12-21 |
2023-08-11 |
cat |
| M L Kemel, M Desban, J Glowinski, C Gauch. Distinct presynaptic control of dopamine release in striosomal and matrix areas of the cat caudate nucleus. Proceedings of the National Academy of Sciences of the United States of America. vol 86. issue 22. 1989-12-21. PMID:2813435. |
(ii) although 10(-6) m atropine completely abolished the cholinergic stimulatory effect on [3h]dopamine release in striosomal area, delayed and prolonged stimulation of [3h]dopamine release was seen with atropine in the matrix. |
1989-12-21 |
2023-08-11 |
cat |
| P T Francis, D M Bowe. Tacrine, a drug with therapeutic potential for dementia: post-mortem biochemical evidence. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 16. issue 4 Suppl. 1989-12-20. PMID:2572313. |
there is evidence that clinical and histopathologic hallmarks of the disease relate to cholinergic and serotonergic dysfunction, with less obvious abnormalities in other neurotransmitters (aspartate, dopamine, gamma-aminobutyrate, glutamate, noradrenaline and somatostatin). |
1989-12-20 |
2023-08-11 |
Not clear |
| K Kolasa, E Palazzi, P Salmoiraghi, G Guiso, S Caccia, S Garattini, S Consol. Mode of action of tiaspirone on the central cholinergic system. Naunyn-Schmiedeberg's archives of pharmacology. vol 340. issue 3. 1989-12-12. PMID:2572973. |
tiaspirone antagonized the striatal acetylcholine increasing effect of apomorphine, a selective dopaminergic receptor agonist, supporting the idea that the drug affects the striatal cholinergic system by a primary action on dopamine receptors. |
1989-12-12 |
2023-08-11 |
rat |
| C Owman, K Fuxe, A M Janson, J Kåhrströ. Chronic nicotine treatment eliminates asymmetry in striatal glucose utilization following unilateral transection of the mesostriatal dopamine pathway in rats. Neuroscience letters. vol 102. issue 2-3. 1989-11-27. PMID:2812507. |
the eliminated asymmetry probably reflects an increased survival of the dopamine neurons and/or of striatal nerve cells on the lesioned side due to protective effects of nicotine resulting from desensitization of nicotinic-type cholinergic receptors following continuous administration of the drug. |
1989-11-27 |
2023-08-11 |
rat |
| R Yamamoto, C Nuki, H Komidori, K Takasak. Effect of l-ephedrine on cholinergic neurotransmission in the isolated guinea pig ileum. Japanese journal of pharmacology. vol 50. issue 4. 1989-10-26. PMID:2550690. |
most of this action of ephedrine appeared to be cholinergic prejunctional in nature, but unrelated to activation of prejunctional alpha 2-adrenoceptors and dopamine sensitive receptors on the cholinergic nerves in this preparation. |
1989-10-26 |
2023-08-11 |
Not clear |
| S L Rea. Update on cholinergic enhancement therapy for Alzheimer disease. Bulletin of clinical neurosciences. vol 52. 1989-10-03. PMID:3334548. |
although patients with alzheimer disease have a well-demonstrated deficit in cortical cholinergic markers, treatments designed to enhance cholinergic activity in the central nervous system have not achieved the clinical success of dopamine replacement for parkinson disease. |
1989-10-03 |
2023-08-11 |
Not clear |
| M Shimoyama, S Kit. Effect of cerulein on in vivo release of acetylcholine from the rat striatum. Brain research. vol 492. issue 1-2. 1989-08-31. PMID:2752307. |
these results suggested that peripherally administered cerulein stimulated striatal cholinergic neurons, that its stimulatory effect on striatal ach release was not mediated by striatal dopamine d2 receptors and that the action of cerulein was, in part, mediated via vagal afferent impulses. |
1989-08-31 |
2023-08-11 |
rat |