| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E K Perry, I McKeith, P Thompson, E Marshall, J Kerwin, S Jabeen, J A Edwardson, P Ince, G Blessed, D Irvin. Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease. Annals of the New York Academy of Sciences. vol 640. 1992-02-28. PMID:1723256. |
quantitative data suggest that although extrapyramidal symptoms relate to striatal levels of dopamine, cognitive impairment is most closely associated with cholinergic (but not monoaminergic) deficits in temporal and archicortical areas. |
1992-02-28 |
2023-08-11 |
Not clear |
| E Nio, K Kogure, T Yae, H Onoder. The effects of maternal ethanol exposure on neurotransmission and second messenger systems: a quantitative autoradiographic study in the rat brain. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1662122. |
quantitative autoradiography was used to map muscarinic cholinergic, dopamine d2, adenosine a1, and inositol 1,4,5-trisphosphate binding sites, as well as to localize adenylate cyclase and protein kinase c. we found no difference in the patterns of staining with acetylcholinesterase and timm's stain between control and prenatally ethanol-exposed rats on postnatal day (pn) 30. |
1992-02-12 |
2023-08-11 |
rat |
| E Nio, K Kogure, T Yae, H Onoder. The effects of maternal ethanol exposure on neurotransmission and second messenger systems: a quantitative autoradiographic study in the rat brain. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1662122. |
in the ethanol-exposed rats, [3h]forskolin binding sites were increased during early development in the ca1 subfield of the hippocampus and the occipital cortex; [3h]phorbol ester binding sites were increased in the cortex, striatum, and hippocampus; hippocampal muscarinic cholinergic sites were increased on pn4 and 30; adenosine a1 binding was reduced on pn10 in most regions examined, but was increased in the ca1 subfield on pn30; dopamine d2 receptor levels were significantly reduced on pn30 in the striatum; and ip3 receptors were decreased in most regions studied, but particularly in the cerebellum. |
1992-02-12 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
cholinergic modulation of [3h]dopamine release from dendrosomes of rat substantia nigra. |
1992-01-09 |
2023-08-11 |
rat |
| M Marchi, A Augliera, A Codignola, G Lunardi, E Fedele, G Fontana, M Raiter. Cholinergic modulation of [3H]dopamine release from dendrosomes of rat substantia nigra. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 3. 1992-01-09. PMID:1961254. |
the data suggest the existence, in the substantia nigra of the rat, of two distinct muscarinic receptor subtypes regulating respectively dopamine release from dopamine dendrites and acetylcholine release from cholinergic nerve terminals. |
1992-01-09 |
2023-08-11 |
rat |
| F Guenaneche, J A Schuurkes, R A Lefebvr. Influence of fenoldopam and quinpirole in the guinea-pig stomach. Journal of autonomic pharmacology. vol 11. issue 4. 1991-11-26. PMID:1682324. |
in circular muscle strips of the gastric corpus, the electrically induced cholinergic contractions were inhibited by dopamine but not consistently influenced by quinpirole or fenoldopam. |
1991-11-26 |
2023-08-11 |
Not clear |
| J N Joyc. Differential response of striatal dopamine and muscarinic cholinergic receptor subtypes to the loss of dopamine. I. Effects of intranigral or intracerebroventricular 6-hydroxydopamine lesions of the mesostriatal dopamine system. Experimental neurology. vol 113. issue 3. 1991-11-19. PMID:1833219. |
quantitative autoradiography was utilized to examine the response of the dopamine (da) and muscarinic cholinergic system within the striatum to lesions of the mesostriatal da system following intranigral 6-hydroxydopamine (6-ohda) injections. |
1991-11-19 |
2023-08-11 |
Not clear |
| M A Nastuk, A M Graybie. Pharmacologically defined M1 and M2 muscarinic cholinergic binding sites in the cat's substantia nigra: development and maturity. Brain research. Developmental brain research. vol 61. issue 1. 1991-11-04. PMID:1914150. |
these findings provide further evidence that the substantia nigra is a site of cholinergic transmission and suggest that the functional balance between acetylcholine and dopamine in the basal ganglia acts here as well as in the striatum. |
1991-11-04 |
2023-08-11 |
cat |
| S Y Lu, M T Shipley, A B Norman, P R Sanber. Striatal, ventral mesencephalic and cortical transplants into the intact rat striatum: a neuroanatomical study. Experimental neurology. vol 113. issue 2. 1991-09-13. PMID:1651254. |
autoradiography for dopamine d1 and d2, muscarinic cholinergic, and serotonin 5-ht1 and 5-ht2 receptors at 5-15 months after transplantation was also investigated. |
1991-09-13 |
2023-08-11 |
rat |
| C Gauchy, M Desban, M O Krebs, J Glowinski, M L Keme. Role of dynorphin-containing neurons in the presynaptic inhibitory control of the acetylcholine-evoked release of dopamine in the striosomes and the matrix of the cat caudate nucleus. Neuroscience. vol 41. issue 2-3. 1991-09-13. PMID:1678500. |
however, the presynaptic cholinergic control of dopamine release is much more complex in the matrix than in the striosomal enriched area. |
1991-09-13 |
2023-08-11 |
cat |
| T Takahashi, S Kurosawa, J W Wiley, C Owyan. Mechanism for the gastrokinetic action of domperidone. In vitro studies in guinea pigs. Gastroenterology. vol 101. issue 3. 1991-09-05. PMID:1860634. |
to test the hypothesis that domperidone stimulates gastric muscle contraction by antagonizing the inhibitory effects of dopamine on postsynaptic cholinergic neurons in the myenteric plexus, the effects of dopamine on circular muscle from the body of the guinea pig stomach were examined. |
1991-09-05 |
2023-08-11 |
Not clear |
| T Takahashi, S Kurosawa, J W Wiley, C Owyan. Mechanism for the gastrokinetic action of domperidone. In vitro studies in guinea pigs. Gastroenterology. vol 101. issue 3. 1991-09-05. PMID:1860634. |
these observations indicate that dopamine inhibits gastric muscle contraction evoked by electric field stimulation by inhibiting cholinergic transmission. |
1991-09-05 |
2023-08-11 |
Not clear |
| M Messripour, Z Shahid. Short- and long-term effects of L-dopa administration on striatal acetylcholinesterase activity. Molecular and chemical neuropathology. vol 13. issue 3. 1991-08-15. PMID:2099784. |
exogenously applied dopamine may interfere with cholinergic activity in the brain. |
1991-08-15 |
2023-08-11 |
rat |
| P Collins, C L Broekkamp, P Jenner, C D Marsde. Drugs acting at D-1 and D-2 dopamine receptors induce identical purposeless chewing in rats which can be differentiated by cholinergic manipulation. Psychopharmacology. vol 103. issue 4. 1991-08-07. PMID:1676528. |
drugs acting at d-1 and d-2 dopamine receptors induce identical purposeless chewing in rats which can be differentiated by cholinergic manipulation. |
1991-08-07 |
2023-08-11 |
rat |
| T M Dawson, V L Dawson, F H Gage, L J Fisher, M A Hunt, J K Wamsle. Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants. Brain research. vol 540. issue 1-2. 1991-07-31. PMID:1905173. |
the findings of downregulation of muscarinic receptors following long-term dopamine denervation and the subsequent normalization of muscarinic receptor density after fetal mesencephalic transplantation suggests that transplanted substantia nigra cells are able to restore inhibitory control on striatal cholinergic interneurons. |
1991-07-31 |
2023-08-11 |
rat |
| E J Mylecharan. 5-HT2 receptor antagonists and migraine therapy. Journal of neurology. vol 238 Suppl 1. 1991-07-18. PMID:2045831. |
these agents have additional antagonistic effects at histamine h1, muscarinic cholinergic, alpha 1-adrenergic, alpha 2-adrenergic and dopamine receptors, but drugs which are selective for these non-5-ht receptors appear to be of no benefit in migraine. |
1991-07-18 |
2023-08-11 |
Not clear |
| C Le Moine, F Tison, B Bloc. D2 dopamine receptor gene expression by cholinergic neurons in the rat striatum. Neuroscience letters. vol 117. issue 3. 1991-07-03. PMID:2094817. |
in situ hybridization with d2 receptor probe and immunohistochemistry with choline acetyltransferase (chat) antibody performed on adjacent sections demonstrate dopamine d2 receptor gene expression in cholinergic neurons of the rat caudate-putamen and nucleus accumbens. |
1991-07-03 |
2023-08-11 |
rat |
| G Damsma, P de Boer, B H Westerink, H C Fibige. Dopaminergic regulation of striatal cholinergic interneurons: an in vivo microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 5. 1991-06-03. PMID:1982560. |
in vivo microdialysis was used to study the putative inhibitory effects of dopamine on cholinergic interneurons in the striatum of conscious rats. |
1991-06-03 |
2023-08-11 |
rat |
| G Damsma, P de Boer, B H Westerink, H C Fibige. Dopaminergic regulation of striatal cholinergic interneurons: an in vivo microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 5. 1991-06-03. PMID:1982560. |
the results of this study reemphasize the importance of the calcium concentration in determining the effects of drugs on central neurotransmitter release, and confirm a role of dopamine in the regulation of striatal cholinergic interneurons. |
1991-06-03 |
2023-08-11 |
rat |
| N Maeda, N Matsuoka, I Yamaguch. Septohippocampal cholinergic pathway and penile erections induced by dopaminergic and cholinergic stimulants. Brain research. vol 537. issue 1-2. 1991-05-23. PMID:1982238. |
the similar results with amantadine and apomorphine suggest that the drugs activate postsynaptic dopamine receptors, which indirectly activate the septohippocampal cholinergic pathway to induce penile erections. |
1991-05-23 |
2023-08-11 |
rat |