Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Bluth, R Langnicke. Effects of haloperidol and low dose clozapine on the acetylcholine turnover rate in rat forebrain structures. Biomedica biochimica acta. vol 44. issue 10. 1986-02-20. PMID:4084256. |
it can be concluded that haloperidol increases the acetylcholine turnover in both striatum and mesolimbic areas by blocking dopamine receptors localized at cholinergic interneurons. |
1986-02-20 |
2023-08-11 |
rat |
V W Hylka, L J Forman, W E Sonntag, J Meite. Effect of CNS-active drugs on TRH-induced prolactin release. Life sciences. vol 38. issue 1. 1986-02-18. PMID:2934599. |
pre-treatment with either the dopamine agonist, piribedil, or the cholinergic agonist, pilocarpine, resulted in significantly reduced trh-induced prl release. |
1986-02-18 |
2023-08-11 |
rat |
M B Anand-Srivastav. Regulation of adenylate cyclase by adenosine and other agonists in rat myocardial sarcolemma. Archives of biochemistry and biophysics. vol 243. issue 2. 1986-01-30. PMID:2417561. |
the myocardial adenylate cyclase was also stimulated by beta-adrenergic agonists, dopamine and glucagon, and inhibited by cholinergic agonists such as carbachol and oxotremorine. |
1986-01-30 |
2023-08-11 |
rat |
L G Hársing, E S Viz. Evidence for multiple dopamine receptors involved in the modulation of acetylcholine release in the striatum. Polish journal of pharmacology and pharmacy. vol 37. issue 3. 1986-01-09. PMID:2866504. |
the involvement of heterogeneous dopamine (da) receptors in the regulation of striatal cholinergic neurotransmission was investigated by measuring the release of acetylcholine (ach) from isolated striatum of the rat. |
1986-01-09 |
2023-08-11 |
rat |
T R Hall, S Harvey, A Chadwic. Effects of putative neurotransmitters on release of prolactin from pituitary glands of the domestic fowl co-incubated with hypothalamic tissue. General pharmacology. vol 16. issue 5. 1985-12-03. PMID:2865191. |
the dopamine antagonist pimozide, but not adrenergic (both alpha and beta), serotoninergic or cholinergic antagonists, prevented the actions of histamine and gaba. |
1985-12-03 |
2023-08-11 |
chicken |
H De Souza, J Palermo-Net. A biochemical study of cholinergic-dopaminergic interactions in the central nervous system. General pharmacology. vol 16. issue 5. 1985-12-03. PMID:4054579. |
the effects of cholinergic (ach) and anti-ach drugs on striatal dopamine (da) levels and turnover were studied. |
1985-12-03 |
2023-08-11 |
Not clear |
A Takashima, T Koik. Relationship between dopamine content and its secretion in PC12 cells as a function of cell growth. Biochimica et biophysica acta. vol 847. issue 1. 1985-12-02. PMID:2864958. |
the pc12 cell line derived from a rat adrenal medullary tumor is known to synthesize dopamine and to release it in response to cholinergic agonists or depolarizing agents. |
1985-12-02 |
2023-08-11 |
rat |
M Marchi, M Raiter. On the presence in the cerebral cortex of muscarinic receptor subtypes which differ in neuronal localization, function and pharmacological properties. The Journal of pharmacology and experimental therapeutics. vol 235. issue 1. 1985-11-08. PMID:3840202. |
the two antagonists did not discriminate between the muscarinic presynaptic receptors sited on cholinergic terminals (muscarinic autoreceptors) and those located on dopamine nerve endings (muscarinic heteroreceptors). |
1985-11-08 |
2023-08-11 |
rat |
R S Flint, J M Murphy, P M Calkins, W J McBrid. Monoamine, amino acid and cholinergic interactions in slices of rat cerebral cortex. Brain research bulletin. vol 15. issue 2. 1985-11-06. PMID:2864115. |
interactions of monoamine, amino acid and cholinergic transmitter systems were studied in slices of rat cerebral cortex using a superfusion procedure and measuring release of endogenous dopamine (da), norepinephrine (ne), serotonin (5-ht), gaba, glutamate (glu) and aspartate (asp). |
1985-11-06 |
2023-08-11 |
rat |
M A Nastuk, A M Graybie. Patterns of muscarinic cholinergic binding in the striatum and their relation to dopamine islands and striosomes. The Journal of comparative neurology. vol 237. issue 2. 1985-10-17. PMID:4031121. |
patterns of muscarinic cholinergic binding in the striatum and their relation to dopamine islands and striosomes. |
1985-10-17 |
2023-08-11 |
human |
M Kusunoki, K Taniyama, C Tanak. Dopamine regulation of [3H]acetylcholine release from guinea-pig stomach. The Journal of pharmacology and experimental therapeutics. vol 234. issue 3. 1985-10-09. PMID:2863371. |
the involvement of dopamine receptors in cholinergic transmission of guinea-pig stomach was investigated by analyzing the effects of dopamine receptor agonists and antagonists on acetylcholine (ach) release from this organ. |
1985-10-09 |
2023-08-11 |
Not clear |
M Kusunoki, K Taniyama, C Tanak. Dopamine regulation of [3H]acetylcholine release from guinea-pig stomach. The Journal of pharmacology and experimental therapeutics. vol 234. issue 3. 1985-10-09. PMID:2863371. |
this effect of dopamine was not altered by 10(-5) m hexamethonium, thereby suggesting that the major dopamine receptors are located on the postganglionic cholinergic neurons. |
1985-10-09 |
2023-08-11 |
Not clear |
M Kusunoki, K Taniyama, C Tanak. Dopamine regulation of [3H]acetylcholine release from guinea-pig stomach. The Journal of pharmacology and experimental therapeutics. vol 234. issue 3. 1985-10-09. PMID:2863371. |
in view of the results, the release of ach from postganglionic cholinergic neurons is probably required through dopamine receptors antagonized by d2 antagonists but not by adrenergic or serotonin receptor antagonists. |
1985-10-09 |
2023-08-11 |
Not clear |
B R Pearce, A M Palmer, D M Bowen, G K Wilcock, M M Esiri, A N Daviso. Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease. Neurochemical pathology. vol 2. issue 4. 1985-10-08. PMID:6085697. |
these are thought to reflect intrinsic cholinergic neurones (choline acetyltransferase activity) and corticostriatal (l-[3h]glutamate binding), nigrostriatal (dopamine and homovanillate concentrations), and ascending brain stem (serotonin, 5-hydroxyindoleacetate, and noradrenaline concentrations) tracts. |
1985-10-08 |
2023-08-12 |
Not clear |
P J Whitehouse, R R Trifiletti, B E Jones, S Folstein, D L Price, S H Snyder, M J Kuha. Neurotransmitter receptor alterations in Huntington's disease: autoradiographic and homogenate studies with special reference to benzodiazepine receptor complexes. Annals of neurology. vol 18. issue 2. 1985-10-07. PMID:2994554. |
in vitro receptor autoradiography was used to construct semiquantitative maps of subtypes of muscarinic cholinergic (labeled with [3h]n-methylscopolamine), benzodiazepine ([3h]flunitrazepam), gamma-aminobutyric acid ([3h]muscimol), dopamine, and serotonin ([3h]spiperone) receptors in frontal cortex, parietal cortex, caudate, putamen, and globus pallidus in tissue sections from 5 patients with clinically well-evaluated huntington's disease and 5 controls matched with respect to age, sex, and postmortem delay. |
1985-10-07 |
2023-08-11 |
Not clear |
J Scheel-Krüger, J Arn. New aspects on the role of dopamine, acetylcholine, and GABA in the development of tardive dyskinesia. Psychopharmacology. Supplementum. vol 2. 1985-07-24. PMID:2987907. |
the results show that the striatum is heterogeneously organized, and the syndromes of biting, gnawing, and licking activities in the rat model involve a complex balance between various dopamine (da), cholinergic, and gabaergic systems within the striatum and the mesolimbic and mesocortical systems. |
1985-07-24 |
2023-08-11 |
rat |
L Baizer, N Weine. Nerve growth factor treatment enhances nicotine-stimulated dopamine release and increases in cyclic adenosine 3':5'-monophosphate levels in PC12 cell cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 5. 1985-06-28. PMID:2987434. |
stimulation of the release of endogenous dopamine by nicotine in these cultures is calcium-dependent and blocked by d-tubocurarine, a specific nicotinic cholinergic antagonist. |
1985-06-28 |
2023-08-11 |
rat |
P Zapata, C Eyzaguirr. Bioelectric potentials in the carotid body. Brain research. vol 331. issue 1. 1985-06-14. PMID:3921196. |
however, cholinergic agents, dopamine and substance p evoked svs which lacked correlation in time-course, amplitude or polarity with changes in sensory frequency. |
1985-06-14 |
2023-08-11 |
cat |
A Ulvestad, T Gerne. Inhibitory effects of dopamine and isoprenaline on antral motor activity stimulated by acetylcholine or physostigmine in vitro. Scandinavian journal of gastroenterology. vol 20. issue 2. 1985-06-05. PMID:3992182. |
this suggests that both dopamine and isoprenaline to some extent act by reducing the spontaneously released acetylcholine, suggesting that both drugs act on intramural cholinergic neural pathways. |
1985-06-05 |
2023-08-11 |
Not clear |
B Costall, R J Naylor, C C Ta. The mechanism of action of dopamine to inhibit field stimulation-induced contractions of guinea pig stomach strips. Naunyn-Schmiedeberg's archives of pharmacology. vol 328. issue 2. 1985-04-19. PMID:6396519. |
that noradrenaline was approximately 10 fold more potent than dopamine, that the dopamine response was not antagonised by the dopamine antagonists haloperidol, domperidone or (-)sulpiride, but was mimicked by the alpha 2-agonist guanfacine and partially antagonised by the alpha 2-adrenoceptor antagonist yohimbine (which could also antagonise the inhibitory actions of guanfacine) would indicate that a component of dopamine's action to reduce cholinergic activity is effected via alpha 2-adrenoceptor mechanisms. |
1985-04-19 |
2023-08-12 |
Not clear |