| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Martin-Jimenez, E Diaz-Rubio, B Sangr. Results of two controlled studies on antiemetic combination against vomiting induced by 5-fluorouracil. Tumori. vol 73. issue 5. 1987-12-30. PMID:3318052. |
these authors suggested that cns receptors other than the classical dopamine d-2 (e.g., histamine h-1 and muscarinic cholinergic receptors) were involved in emetic response. |
1987-12-30 |
2023-08-11 |
Not clear |
| E Moyse, W Rostène, M Vial, K Leonard, J Mazella, P Kitabgi, J P Vincent, A Beaude. Distribution of neurotensin binding sites in rat brain: a light microscopic radioautographic study using monoiodo [125I]Tyr3-neurotensin. Neuroscience. vol 22. issue 2. 1987-12-17. PMID:3313097. |
such putative "neurotensinoceptive" projection systems might involve part of the mesostriatal, mesocortical and mesolimbic dopamine systems, as well as the raphe-prosencephalic serotonin system and the habenulo-interpeduncular and basal forebrain-cortical cholinergic systems. |
1987-12-17 |
2023-08-11 |
rat |
| P Jenner, C D Marsde. Chronic pharmacological manipulation of dopamine receptors in brain. Neuropharmacology. vol 26. issue 7B. 1987-10-29. PMID:2889159. |
the functional supersensitivity of dopamine receptors produced by repeated administration of neuroleptic is reflected in changes in cholinergic, gamma-aminobutyric acid (gaba), 5-hydroxytryptamine (5-ht) and peptide neuronal systems. |
1987-10-29 |
2023-08-11 |
rat |
| A Hilditch, G M Dre. Subclassification of peripheral dopamine receptors. Clinical and experimental hypertension. Part A, Theory and practice. vol 9. issue 5-6. 1987-10-13. PMID:3621630. |
the neuronal dopamine receptors on the cholinergic nerve terminals of the rabbit rectococcygeus muscle appear different from other neuronal receptors. |
1987-10-13 |
2023-08-11 |
human |
| S Consolo, C F Wu, R Fus. D-1 receptor-linked mechanism modulates cholinergic neurotransmission in rat striatum. The Journal of pharmacology and experimental therapeutics. vol 242. issue 1. 1987-08-31. PMID:2886638. |
in agreement with these findings, sch 23390 amplified the action of amphetamine, a dopamine releaser, on striatal cholinergic neurons. |
1987-08-31 |
2023-08-11 |
rat |
| G M Gilad, J M Rabey, V H Gila. Presynaptic effects of glucocorticoids on dopaminergic and cholinergic synaptosomes. Implications for rapid endocrine-neural interactions in stress. Life sciences. vol 40. issue 25. 1987-07-10. PMID:3035312. |
we conclude: a) high glucocorticoid concentrations and not adrenocorticotropin can directly enhance acetylcholine release but only from stimulated cholinergic synaptosomes, and b) high glucocorticoids can reduce dopamine uptake by dopaminergic synaptosomes. |
1987-07-10 |
2023-08-11 |
rat |
| S J Peroutk. Chemotherapeutic agents do not interact with neurotransmitter receptors. Cancer chemotherapy and pharmacology. vol 19. issue 2. 1987-06-05. PMID:3568270. |
each drug was inactive at concentrations as high as 10(-4) m in displacing the specific binding of 3h-spiperone to dopamine d2, 3h-pyrilamine to histamine h1, and 3h-quinuclidinyl benzilate to muscarinic cholinergic receptors. |
1987-06-05 |
2023-08-11 |
Not clear |
| M Martin-Jimenez, E Diaz-Rubio, J L Gonzalez Larriba, B Sangr. Antiemetic combination for PAC (cisplatin-adriamycin-cyclophosphamide) chemotherapy-induced emesis in ovarian cancer. European journal of gynaecological oncology. vol 8. issue 2. 1987-05-27. PMID:3552683. |
the antiemetic combination was designed in an attempt to act simultaneously on gastrointestinal motility and neuroreceptors at the central emetic pathways (dopamine d-2, histamine h-1 and muscarinic cholinergic). |
1987-05-27 |
2023-08-11 |
Not clear |
| G Delitala, M Palermo, R Ross, D Coy, M Besser, A Grossma. Dopaminergic and cholinergic influences on the growth hormone response to growth hormone-releasing hormone in man. Neuroendocrinology. vol 45. issue 3. 1987-05-21. PMID:2882435. |
we have, therefore, investigated the effect of a dopamine agonist, bromocriptine, and a dopamine antagonist, domperidone, as well as a muscarinic cholinergic antagonist, pirenzepine, on the gh response to an analogue of gh-releasing hormone (ghrh) in normal male subjects. |
1987-05-21 |
2023-08-11 |
human |
| G Delitala, M Palermo, R Ross, D Coy, M Besser, A Grossma. Dopaminergic and cholinergic influences on the growth hormone response to growth hormone-releasing hormone in man. Neuroendocrinology. vol 45. issue 3. 1987-05-21. PMID:2882435. |
as this dose of ghrh(1-29) nh2 has been shown to be maximally stimulatory to gh release, it is suggested that there are dopamine stimulatory and cholinergic inhibitory receptors to gh release independent of ghrh in man. |
1987-05-21 |
2023-08-11 |
human |
| R Fog, L Regeu. Neuropharmacology of tics. Revue neurologique. vol 142. issue 11. 1987-04-21. PMID:2881341. |
other attempts to change brain dopamine in different ways using cholinergic, gabaergic, and peptidergic drugs have given rather poor clinical results. |
1987-04-21 |
2023-08-11 |
Not clear |
| O Barochovsky, H F Bradfor. Modulation of dopamine release from neuron-enriched tissue cultures by cholinergic agents. Journal of neurochemistry. vol 48. issue 3. 1987-03-19. PMID:3806105. |
modulation of dopamine release from neuron-enriched tissue cultures by cholinergic agents. |
1987-03-19 |
2023-08-11 |
rat |
| O Barochovsky, H F Bradfor. Modulation of dopamine release from neuron-enriched tissue cultures by cholinergic agents. Journal of neurochemistry. vol 48. issue 3. 1987-03-19. PMID:3806105. |
modulation of [3h]dopamine release by cholinergic agents (acetylcholine, atropine, d-tubocurarine, oxotremorine, and nicotine) was studied in primary cell cultures derived from whole brains of foetal rats (17 days of gestation). |
1987-03-19 |
2023-08-11 |
rat |
| O Barochovsky, H F Bradfor. Modulation of dopamine release from neuron-enriched tissue cultures by cholinergic agents. Journal of neurochemistry. vol 48. issue 3. 1987-03-19. PMID:3806105. |
these results show that dopamine release in both types of neuron-enriched cultures can be influenced by cholinergic agents and that both muscarinic and nicotinic receptors are involved in regulation of the amine's outflow. |
1987-03-19 |
2023-08-11 |
rat |
| W T Chiu, L S Lin, C J Shih, M T Li. Bombesin-induced hypothermia: possible involvement of cholinergic and dopaminergic receptors in the rat hypothalamus. Experimental neurology. vol 95. issue 2. 1987-03-17. PMID:2879738. |
the thermal responses of rats which were pretreated with 5,7-dihydroxytryptamine to deplete hypothalamic 5-hydroxytryptamine, 6-hydroxydopamine to deplete hypothalamic catecholamines, phentolamine and propranolol to inhibit adrenergic receptors, haloperidol to inhibit dopamine receptors, or atropine to inhibit cholinergic receptors, to intrahypothalamic administration of bombesin were compared with those of control rats. |
1987-03-17 |
2023-08-11 |
rat |
| G F Weiss, P Papadakos, K Knudson, S F Leibowit. Medial hypothalamic serotonin: effects on deprivation and norepinephrine-induced eating. Pharmacology, biochemistry, and behavior. vol 25. issue 6. 1987-03-17. PMID:3027720. |
while the effect of 5-ht was somewhat attenuated by administration of certain beta-adrenergic and phenothiazine-type dopamine receptor antagonists, 5-ht was totally resistant to the actions of more selective dopamine blockers and of the cholinergic and histaminergic antagonists, atropine and dexbrompheniramine. |
1987-03-17 |
2023-08-11 |
rat |
| M Martin-Jimenez, E Diaz-Rubi. Clinical evaluation of the simultaneous blockade of the dopamine D-2, histamine H-1, and muscarinic cholinergic receptors in cancer chemotherapy-induced emesis: results of a controlled trial. Cancer chemotherapy and pharmacology. vol 18. issue 2. 1987-02-04. PMID:2947734. |
clinical evaluation of the simultaneous blockade of the dopamine d-2, histamine h-1, and muscarinic cholinergic receptors in cancer chemotherapy-induced emesis: results of a controlled trial. |
1987-02-04 |
2023-08-11 |
Not clear |
| M Martin-Jimenez, E Diaz-Rubi. Clinical evaluation of the simultaneous blockade of the dopamine D-2, histamine H-1, and muscarinic cholinergic receptors in cancer chemotherapy-induced emesis: results of a controlled trial. Cancer chemotherapy and pharmacology. vol 18. issue 2. 1987-02-04. PMID:2947734. |
this combination was designed to obtain a simultaneous blockade of the dopamine d-2, histamine h-1, and muscarinic cholinergic receptors of the central structures responsible for emesis (chemoreceptor trigger zone and vomiting center). |
1987-02-04 |
2023-08-11 |
Not clear |
| M C Aguila, S M McCan. Evidence that growth hormone-releasing factor stimulates somatostatin release in vitro via beta-endorphin. Endocrinology. vol 120. issue 1. 1987-01-20. PMID:2877865. |
studies using receptor blockers for dopamine (pimozide), alpha-adrenergic receptors (phentolamine), and muscarinic cholinergic receptors (atropine) revealed that these receptor blockers, at a dose of 10(-6) m, which was capable of blocking the response to the relevant transmitter in previous studies, had no effect on basal release of srif in the static incubation system and failed to modify the response to grf (10(-10) m). |
1987-01-20 |
2023-08-11 |
rabbit |
| Y Shafrir, Y Levy, A Beharab, M Nitzam, R Steinher. Acute dystonic reaction to bethanechol--a direct acetylcholine receptor agonist. Developmental medicine and child neurology. vol 28. issue 5. 1987-01-14. PMID:2877910. |
this first report of acute dystonic reaction to cholinergic agonists in human is in accord with the current theories of the rôle of acetylcholine and dopamine in the pathogenesis of acute dystonic reactions. |
1987-01-14 |
2023-08-11 |
human |