| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S N Habe. Neurotransmitters in the human and nonhuman primate basal ganglia. Human neurobiology. vol 5. issue 3. 1986-12-09. PMID:2876974. |
these include: the well-described terminal fields in the striatum which originate from the brain stem and contain the monoamines, dopamine and serotonin; amino acid containing axons projecting from the cortex and thalamus; striatal cholinergic and peptide-positive interneurons; and amino acid and peptide containing projection neurons to the globus pallidus and substantia nigra. |
1986-12-09 |
2023-08-11 |
human |
| A M Graybiel, R W Baughman, F Eckenstei. Cholinergic neuropil of the striatum observes striosomal boundaries. Nature. vol 323. issue 6089. 1986-11-25. PMID:3773990. |
acetylcholine and dopamine are key neurotransmitters in the extrapyramidal motor system, where they are thought to lie in a 'functional balance' brought about by interactions between the terminals of the dopamine-containing nigrostriatal tract and the cholinergic interneurones of the striatum. |
1986-11-25 |
2023-08-11 |
Not clear |
| E Kelly, S R Nahorsk. Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:2428936. |
specific inhibition of dopamine d-1-mediated cyclic amp formation by dopamine d-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices. |
1986-11-19 |
2023-08-11 |
rat |
| E Kelly, S R Nahorsk. Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:2428936. |
in the presence of 1 mm 3-isobutyl-1-methylxanthine, dopamine d-2, muscarinic cholinergic, and opiate receptor stimulation by ru 24926, carbachol, and morphine (all at 10(-8)-10(-5) m), respectively, inhibited the increase in cyclic amp accumulation in slices of rat striatum due to dopamine d-1 receptor stimulation by 1 microm skf 38393. |
1986-11-19 |
2023-08-11 |
rat |
| E Kelly, S R Nahorsk. Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices. Journal of neurochemistry. vol 47. issue 5. 1986-11-19. PMID:2428936. |
these results suggest that in rat striatum either dopamine d-2, muscarinic cholinergic, and opiate receptors are only functionally linked to dopamine d-1 receptors or that the d-1 and d-2 receptors linked to adenylate cyclase lie on the cells, distinct from other receptors capable of elevating striatal cyclic amp levels. |
1986-11-19 |
2023-08-11 |
rat |
| W H Tsai, D G Pur. Dopamine modulates evoked transmission at cholinergic synapses formed by rat retinal neurons with muscle cells. Brain research. vol 380. issue 2. 1986-11-18. PMID:2875761. |
dopamine modulates evoked transmission at cholinergic synapses formed by rat retinal neurons with muscle cells. |
1986-11-18 |
2023-08-11 |
rat |
| W H Tsai, D G Pur. Dopamine modulates evoked transmission at cholinergic synapses formed by rat retinal neurons with muscle cells. Brain research. vol 380. issue 2. 1986-11-18. PMID:2875761. |
the purpose of this study was to investigate the effect of dopamine on synaptic transmission mediated by cholinergic neurons derived from the rat retina. |
1986-11-18 |
2023-08-11 |
rat |
| L H Tecott, L L Kwong, S Uhr, S J Peroutk. Differential modulation of dopamine D2 receptors by chronic haloperidol, nitrendipine, and pimozide. Biological psychiatry. vol 21. issue 12. 1986-11-14. PMID:2428411. |
no alterations in muscarinic cholinergic sites, dopamine uptake sites, or calcium channel antagonist sites result following chronic drug administration. |
1986-11-14 |
2023-08-11 |
rat |
| M Martín Jiménez, E Diaz-Rubi. Antiemetic combination for cisplatin-induced emesis. Results from a controlled study. Bulletin du cancer. vol 73. issue 3. 1986-11-13. PMID:3756365. |
this combination was designed in an attempt to act simultaneously on gastrointestinal motility and neuroreceptors at central emetic pathways (dopamine d-2, histamine h-1 and muscarinic cholinergic). |
1986-11-13 |
2023-08-11 |
Not clear |
| A Dahlström, P A Larsson, M Goldstein, K Lundmark, A G Dahllöf, S Böö. Immunocytochemical studies on axonal transport in adrenergic and cholinergic nerves using cytofluorimetric scanning. Medical biology. vol 64. issue 2-3. 1986-09-30. PMID:2875231. |
the substances must be made fluorescent, and in this study we have investigated noradrenaline (na), using formaldehyde induced fluorescence, and dopamine beta-hydroxylase (dbh), tyrosine hydroxylase (th), neuropeptide y (npy) and two cholinergic vesicle components (a transmembrane glycoprotein and synapsin i) using indirect immunofluorescence. |
1986-09-30 |
2023-08-11 |
rat |
| C Dwivedi, E C James, S S Parma. Effects of abnormal metabolites of maple syrup urine disease on neurotransmitter receptor binding. Biochemical medicine and metabolic biology. vol 35. issue 3. 1986-08-21. PMID:3013257. |
no significant changes were observed in binding of cholinergic, gaba, and dopamine receptors binding in appropriate rat brain preparations. |
1986-08-21 |
2023-08-11 |
rat |
| M A Zarbin, J K Wamsley, J M Palacios, M J Kuha. Autoradiographic localization of high affinity GABA, benzodiazepine, dopaminergic, adrenergic and muscarinic cholinergic receptors in the rat, monkey and human retina. Brain research. vol 374. issue 1. 1986-07-29. PMID:3013364. |
high affinity gamma-aminobutyric acid, benzodiazepine, strychnine (glycine), dopamine, spirodecanone, alpha 1-adrenergic, alpha 2-adrenergic, beta-adrenergic and muscarinic cholinergic binding sites were localized by semiquantitative autoradiography in rat and, in some instances, in monkey and human retinae using [3h]muscimol, [3h]flunitrazepam, [3h]strychnine, [3h]spiperone, [3h]prazosin, [3h]para-aminoclonidine, [3h]dihydroalprenolol and [3h]quinuclidinyl benzylate, respectively. |
1986-07-29 |
2023-08-11 |
human |
| F Yamagishi, K Haruta, N Homma, K Iwatsuki, S Chib. Metoclopramide enhances bethanechol-induced pancreatic exocrine secretion of the dog. Clinical and experimental pharmacology & physiology. vol 12. issue 6. 1986-07-24. PMID:2871953. |
from these results, it is concluded that metoclopramide enhances secretory responses to cholinergic stimulations by peripherally sensitizing the muscarinic receptor-mediated exocrine process and this drug is a weaker antagonist of the dopamine d2 receptors than sulpiride. |
1986-07-24 |
2023-08-11 |
dog |
| H Somme. [Thoughts on the neurobiological aspects of Parkinson syndrome]. Psychiatrie, Neurologie, und medizinische Psychologie. vol 38. issue 2. 1986-06-17. PMID:3010357. |
the inhibition or the optimal balance of the cholinergic systems is the effect of dopamin and noradrenalin. |
1986-06-17 |
2023-08-11 |
Not clear |
| T S Kilduff, S S Bowersox, K I Kaitin, T L Baker, R D Ciaranello, W C Demen. Muscarinic cholinergic receptors and the canine model of narcolepsy. Sleep. vol 9. issue 1 Pt 2. 1986-06-12. PMID:3704431. |
this up-regulation of brainstem cholinergic receptors suggests a problem with release of acetylcholine, which, together with previous reports of an impairment of dopamine release, may be indicative of a fundamental membrane problem in narcolepsy. |
1986-06-12 |
2023-08-11 |
Not clear |
| L Lima, T L Sourke. Cholinergic and GABAergic regulation of dopamine beta-hydroxylase activity in the adrenal gland of the rat. The Journal of pharmacology and experimental therapeutics. vol 237. issue 1. 1986-05-15. PMID:2937909. |
cholinergic and gabaergic regulation of dopamine beta-hydroxylase activity in the adrenal gland of the rat. |
1986-05-15 |
2023-08-11 |
rat |
| H Simon, K Taghzouti, M Le Moa. Deficits in spatial-memory tasks following lesions of septal dopaminergic terminals in the rat. Behavioural brain research. vol 19. issue 1. 1986-05-13. PMID:3006722. |
the lesions were shown to have selectively depleted dopamine concentrations in the septum without damaging noradrenergic terminals or cholinergic cell bodies. |
1986-05-13 |
2023-08-11 |
rat |
| F H Gage, A Björklun. Intracerebral grafting of neuronal cell suspensions into the adult brain. Central nervous system trauma : journal of the American Paralysis Association. vol 1. issue 1. 1986-04-10. PMID:6400200. |
experiments are described involving fetal dopamine cells transplanted to adult striatum and fetal cholinergic cells transplanted to the hippocampal formation, as primary examples. |
1986-04-10 |
2023-08-12 |
Not clear |
| H N Wagne. Quantitative imaging of neuroreceptors in the living human brain. Seminars in nuclear medicine. vol 16. issue 1. 1986-03-26. PMID:3003920. |
pet scans make it possible to assess the state of neurotransmitter receptors, such as the dopamine, serotonin, muscarinic cholinergic, opiate, and benzodiazepine receptors, in different regions in normal persons and patients with neuropsychiatric diseases. |
1986-03-26 |
2023-08-11 |
human |
| J A Schuurkes, L F Helsen, J M Van Nuete. A comparative study on the effects of domperidone, metoclopramide, clebopride and trimebutine on the gastro-duodenal preparation of the guinea pig. Japanese journal of pharmacology. vol 39. issue 2. 1986-03-21. PMID:4087563. |
domperidone (dopamine antagonist), metoclopramide and clebopride (both dopamine antagonists and stimulators of the intramural cholinergic system), and trimebutine (spasmolytic) are used in the treatment of digestive disorders such as dyspepsia or gastritis. |
1986-03-21 |
2023-08-11 |
Not clear |