| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alberto Muñoz, Jon Ignacio Arellano, Javier DeFelip. GABABR1 receptor protein expression in human mesial temporal cortex: changes in temporal lobe epilepsy. The Journal of comparative neurology. vol 449. issue 2. 2002-08-27. PMID:12115687. |
the highest density of gaba(b)r1a-b-ir neurons was localized in the stratum pyramidale, where virtually every pyramidal cell was intensely immunoreactive, including the proximal part of the apical dendrites. |
2002-08-27 |
2023-08-12 |
human |
| Katherine L Perkin. GABA application to hippocampal CA3 or CA1 stratum lacunosum-moleculare excites an interneuron network. Journal of neurophysiology. vol 87. issue 3. 2002-05-20. PMID:11877515. |
these data indicate that the gpsc recorded in pyramidal cells that was triggered by focal gaba application resulted from the synchronous synaptic release of gaba from activated interneurons rather than from the binding of exogenous gaba to receptors on the pyramidal cell. |
2002-05-20 |
2023-08-12 |
Not clear |
| C N Rudick, C S Woolle. Estrogen regulates functional inhibition of hippocampal CA1 pyramidal cells in the adult female rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 17. 2001-09-20. PMID:11517242. |
the concurrent enhancement of gaba(a) and nmda-mediated input to ca1 pyramidal cells restores a balance of excitatory and inhibitory input to these cells and increases the potential dynamic range of ca1 pyramidal cell responses to synaptic input. |
2001-09-20 |
2023-08-12 |
rat |
| A B Ali, J Rossier, J F Staiger, E Audina. Kainate receptors regulate unitary IPSCs elicited in pyramidal cells by fast-spiking interneurons in the neocortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312283. |
fs to pyramidal cell unitary ipscs were depressed by (rs)-s-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl) (atpa), a kainate (ka) receptor agonist, and by the endogenous agonist l-glutamate in the presence of ampa, nmda, mglur, and gaba(b) receptor antagonists. |
2001-06-07 |
2023-08-12 |
Not clear |
| J DeFelipe, J I Arellano, A Gómez, E C Azmitia, A Muño. Pyramidal cell axons show a local specialization for GABA and 5-HT inputs in monkey and human cerebral cortex. The Journal of comparative neurology. vol 433. issue 1. 2001-05-24. PMID:11283956. |
pyramidal cell axons show a local specialization for gaba and 5-ht inputs in monkey and human cerebral cortex. |
2001-05-24 |
2023-08-12 |
human |
| G Nyíri, T F Freund, P Somogy. Input-dependent synaptic targeting of alpha(2)-subunit-containing GABA(A) receptors in synapses of hippocampal pyramidal cells of the rat. The European journal of neuroscience. vol 13. issue 3. 2001-04-26. PMID:11168550. |
because the two basket cell types innervate the same domain of the pyramidal cell, the results indicate that pyramidal cells have mechanisms to target gaba(a) receptors, under presynaptic influence, preferentially to distinct synapses. |
2001-04-26 |
2023-08-12 |
rat |
| V Gundersen, F Fonnum, O P Ottersen, J Storm-Mathise. Redistribution of neuroactive amino acids in hippocampus and striatum during hypoglycemia: a quantitative immunogold study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 21. issue 1. 2001-04-05. PMID:11149667. |
aspartate was enriched along with glutamate in nerve terminals forming asymmetric synapses on spines and with gaba in terminals forming symmetric synapses on granule and pyramidal cell bodies. |
2001-04-05 |
2023-08-12 |
rat |
| K Shimono, F Brucher, R Granger, G Lynch, M Taketan. Origins and distribution of cholinergically induced beta rhythms in hippocampal slices. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 22. 2001-02-22. PMID:11069954. |
it is concluded that cholinergically driven beta rhythms arise independently in hippocampal subfields from oscillatory circuits involving (1) bursts of pyramidal cell discharges, (2) activation of a subset of feedback interneurons that project apically, and (3) production of a gaba(a)-mediated hyperpolarization in the outer portions of the apical dendrites of pyramidal neurons. |
2001-02-22 |
2023-08-12 |
Not clear |
| X J Zeng, E I Tiet. Role of bicarbonate ion in mediating decreased synaptic conductance in benzodiazepine tolerant hippocampal CA1 pyramidal neurons. Brain research. vol 868. issue 2. 2000-08-18. PMID:10854572. |
gaba(a) receptors located on pyramidal cell somata or dendrites were activated monosynaptically by maximal stimulation of gabaergic terminals at the stratum oriens-pyramidale (so-sp) or stratum lacunosum-molecular (s-l-m) border, respectively. |
2000-08-18 |
2023-08-12 |
rat |
| R A Lenz, B E Alge. Calcium dependence of depolarization-induced suppression of inhibition in rat hippocampal CA1 pyramidal neurons. The Journal of physiology. vol 521 Pt 1. 2000-02-14. PMID:10562341. |
dsi is a retrograde signalling process in which voltage-dependent ca2+ influx into a pyramidal cell leads to a transient decrease in the release of gaba from interneurons. |
2000-02-14 |
2023-08-12 |
rat |
| K J Staley, W R Procto. Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport. The Journal of physiology. vol 519 Pt 3. 1999-12-21. PMID:10457084. |
using a standard model of membrane potential, these conditions are demonstrated to be sufficient to produce the experimentally observed, activity-dependent gaba(a) depolarizing response in pyramidal cell dendrites. |
1999-12-21 |
2023-08-12 |
rat |
| M Frerking, C C Petersen, R A Nicol. Mechanisms underlying kainate receptor-mediated disinhibition in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 22. 1999-12-10. PMID:10536023. |
ka caused a decrease in pyramidal cell input resistance, which was reduced by gaba(a) receptor antagonists. |
1999-12-10 |
2023-08-12 |
Not clear |
| L A Martin, B E Alge. Muscarinic facilitation of the occurrence of depolarization-induced suppression of inhibition in rat hippocampus. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392830. |
when recorded under whole-cell voltage clamp, monosynaptic, bicuculline-sensitive, gaba(a)-mediated currents are suppressed for a period lasting up to 1 min in response to a retrograde signal released by the pyramidal cell. |
1999-10-06 |
2023-08-12 |
rat |
| K L Perkin. Cl- accumulation does not account for the depolarizing phase of the synaptic GABA response in hippocampal pyramidal cells. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444675. |
to test whether the sigpsc lacked a gaba(d) component because it was generated predominantly at the soma, where less of an increase in [cl-](i) would occur, picrotoxin was applied to the soma of the pyramidal cell. |
1999-09-23 |
2023-08-12 |
Not clear |
| E I Tietz, X Huang, S Chen, W F Ferenca. Temporal and regional regulation of alpha1, beta2 and beta3, but not alpha2, alpha4, alpha5, alpha6, beta1 or gamma2 GABA(A) receptor subunit messenger RNAs following one-week oral flurazepam administration. Neuroscience. vol 91. issue 1. 1999-08-02. PMID:10336082. |
decreased "alpha1-specific" silver grain density over a subclass of interneurons at the pyramidal cell border suggested concomitant regulation of interneuron gaba(a) receptors. |
1999-08-02 |
2023-08-12 |
rat |
| P M Steele, M D Mau. Inhibitory control of LTP and LTD: stability of synapse strength. Journal of neurophysiology. vol 81. issue 4. 1999-05-13. PMID:10200191. |
because one source of gabaergic input to ca1 pyramidal cells is via recurrent inhibition, we tested the prediction that elevated postsynaptic spike activity would increase feedback gaba inhibition and favor the induction of ltd. by using an induction stimulation of 8 hz, which alone produced no net change in synaptic strength, we found that stimulation presented during antidromic activation of pyramidal cell spikes induced ltd. |
1999-05-13 |
2023-08-12 |
Not clear |
| E D Menschik, L H Finke. Neuromodulatory control of hippocampal function: towards a model of Alzheimer's disease. Artificial intelligence in medicine. vol 13. issue 1-2. 1998-09-24. PMID:9654381. |
the network is based on the 66-compartment hippocampal pyramidal cell model of traub and colleagues and their 51-compartment interneuron interconnected with realistic ampa-, nmda-, and gaba(a)-mediated synapses. |
1998-09-24 |
2023-08-12 |
Not clear |
| J F Flood, K Uezu, J E Morle. The cortical neuropeptide, cortistatin-14, impairs post-training memory processing. Brain research. vol 775. issue 1-2. 1998-03-09. PMID:9439854. |
in the hippocampus, cortistatin-14 inhibits pyramidal cell firing and co-exists with gaba. |
1998-03-09 |
2023-08-12 |
mouse |
| D Ruano, D Perrais, J Rossier, N Roper. Expression of GABA(A) receptor subunit mRNAs by layer V pyramidal cells of the rat primary visual cortex. The European journal of neuroscience. vol 9. issue 4. 1997-07-24. PMID:9153593. |
in layer v pyramidal cells, a total of ten gaba(a) receptor subunit mrnas could be detected, with a mean of seven subunit mrnas per cell, suggesting gaba(a) receptor heterogeneity within a single pyramidal cell. |
1997-07-24 |
2023-08-12 |
rat |
| K K Miller, C R Lupic. Neuropeptide FF inhibition of morphine effects in the rat hippocampus. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098532. |
electrophysiologically, this pyramidal cell excitation is mainfest as an increase in extracellularly recorded population spikes, while the reduction in synaptic gaba release is manifest as a decrease in the amplitude of intracellularly recorded inhibitory postsynaptic potentials (ipsps). |
1997-06-17 |
2023-08-12 |
rat |