| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S G Beck, S Birnstiel, K C Choi, W A Poulio. Fluoxetine selectively alters 5-hydroxytryptamine1A and gamma-aminobutyric acidB receptor-mediated hyperpolarization in area CA1, but not area CA3, hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 281. issue 1. 1997-05-02. PMID:9103487. |
the hippocampal pyramidal cell characteristics and the 5-ht1a and gaba(b) receptor-mediated hyperpolarization were measured in the ca1 and the ca3 subfields. |
1997-05-02 |
2023-08-12 |
rat |
| S R Sesack, C L Snyder, D A Lewi. Axon terminals immunolabeled for dopamine or tyrosine hydroxylase synapse on GABA-immunoreactive dendrites in rat and monkey cortex. The Journal of comparative neurology. vol 363. issue 2. 1996-07-16. PMID:8642074. |
however, it has not been established whether dopamine also modulates pyramidal cell activity indirectly through synapses on gamma-aminobutyric acid (gaba) interneurons, and whether such inputs differ across cortical regions and species. |
1996-07-16 |
2023-08-12 |
rat |
| R J Siarey, M Andreasen, J D Lamber. Serotoninergic modulation of excitability in area CA1 of the in vitro rat hippocampus. Neuroscience letters. vol 199. issue 3. 1996-03-13. PMID:8577400. |
this, in combination with a 5ht3 receptor-mediated reduction in gamma-aminobutyric acid (gaba)-ergic inhibition, leads to an increase in pyramidal cell excitability evident as epileptic field potentials. |
1996-03-13 |
2023-08-12 |
rat |
| T N Ricciardi, A T Malou. Differential effects of zinc on hyperpolarizing and depolarizing GABAA synaptic potentials in hippocampal slice cultures. Brain research. vol 680. issue 1-2. 1995-10-10. PMID:7663987. |
this inhibition of fast hyperpolarizing potentials suggests that zn2+ may reduce the release of gaba onto pyramidal cell somata. |
1995-10-10 |
2023-08-12 |
Not clear |
| T N Ricciardi, A T Malou. Differential effects of zinc on hyperpolarizing and depolarizing GABAA synaptic potentials in hippocampal slice cultures. Brain research. vol 680. issue 1-2. 1995-10-10. PMID:7663987. |
these observations suggest that zn2+ enhances gaba release from local circuit neurons that synapse onto pyramidal cell dendrites, and inhibits gaba release onto pyramidal cell somata. |
1995-10-10 |
2023-08-12 |
Not clear |
| E Thiels, G Barrionuevo, T W Berge. Excitatory stimulation during postsynaptic inhibition induces long-term depression in hippocampus in vivo. Journal of neurophysiology. vol 72. issue 6. 1995-04-25. PMID:7897506. |
the inhibition of pyramidal cell activity was mediated by input to the pyramidal cells from local gamma-aminobutyric acid (gaba)-releasing interneurons activated by commissural fibers and/or ca1 recurrent collaterals, because the inhibition was eliminated by local administration of the selective gabaa receptor antagonist, bicuculline (50 microm), near the recording site. |
1995-04-25 |
2023-08-12 |
rat |
| F F Johanse. Interneurons in rat hippocampus after cerebral ischemia. Morphometric, functional, and therapeutic investigations. Acta neurologica Scandinavica. Supplementum. vol 150. 1994-04-13. PMID:7907456. |
the object is to verify if the interneurons die or survive after an ischemic insult, and study if ischemia changes gaba inhibition in the period preceding delayed ca1 pyramidal cell death. |
1994-04-13 |
2023-08-12 |
rat |
| F F Johanse. Interneurons in rat hippocampus after cerebral ischemia. Morphometric, functional, and therapeutic investigations. Acta neurologica Scandinavica. Supplementum. vol 150. 1994-04-13. PMID:7907456. |
furthermore, gaba can readily be released upon potassium stimulation in the period preceding ca1 pyramidal cell death. |
1994-04-13 |
2023-08-12 |
rat |
| R Torp, B Arvin, E Le Peillet, A G Chapman, O P Ottersen, B S Meldru. Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87. Experimental brain research. vol 96. issue 3. 1994-03-08. PMID:7905421. |
aspartate-like immunoreactivity was substantially reduced in pyramidal cell somata both immediately and 60 min after ischaemia, while profiles that were immunopositive for gaba in control brains showed increased gaba immunolabelling. |
1994-03-08 |
2023-08-12 |
rat |
| A Dresse, J Scuvée-Moreau, E Mocaaër, J C Poignan. [Contribution of electrophysiology to the study of tianeptine and other antidepressive agents]. Presse medicale (Paris, France : 1983). vol 20. issue 37. 1992-01-30. PMID:1836612. |
iontophoretic application of clomipramine increases pyramidal cell response to serotonin but not to gaba and lengthens the recovery time after serotonin and gaba. |
1992-01-30 |
2023-08-11 |
Not clear |
| F F Johansen, N H Dieme. Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta neurologica Scandinavica. vol 84. issue 1. 1991-11-21. PMID:1656687. |
therefore we investigated the possible neuroprotective effect of the gaba uptake inhibitor, r-(-)-1-(4,4-(3-methyl-2-thienyl)-3-butenyl)-3-piperidine carboxylic acid (no-328), in a rat cerebral ischemia model of delayed ca1 pyramidal cell death. |
1991-11-21 |
2023-08-11 |
rat |
| F F Johansen, T Christensen, M S Jensen, E Valente, C V Jensen, T Nathan, J D Lambert, N H Dieme. Inhibition in postischemic rat hippocampus: GABA receptors, GABA release, and inhibitory postsynaptic potentials. Experimental brain research. vol 84. issue 3. 1991-09-11. PMID:1650706. |
this conclusion taken together with the observation that postischemic 3h-ro-15-1788 binding in hippocampus declined, suggest that benzodiazepines (by increasing the receptor affinity), gaba analogs, and gaba uptake inhibitors may be useful in the treatment of ischemic ca1 pyramidal cell death in the rat. |
1991-09-11 |
2023-08-11 |
rat |
| D V Madison, R A Nicol. Norepinephrine decreases synaptic inhibition in the rat hippocampus. Brain research. vol 442. issue 1. 1988-06-02. PMID:2834010. |
this disinhibitory effect of ne appears to be mediated by an alpha-receptor, and occurs at a site presynaptic to the pyramidal cell, since ne does not change the reversal potential of the ipsp nor does it affect the amplitude or the reversal potential of iontophoretic gaba responses. |
1988-06-02 |
2023-08-11 |
rat |
| R Dingledine, M A Hynes, G L Kin. Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice. The Journal of physiology. vol 380. 1987-09-24. PMID:2886653. |
we propose that, under normal (non-epileptic) physiological conditions, the balance between synaptic inhibition mediated by gaba receptors and synaptic excitation mediated by nmda receptors may modulate the excitability of pyramidal cell dendrites. |
1987-09-24 |
2023-08-11 |
rat |
| J M Shen, A R Kriegstei. Turtle hippocampal cortex contains distinct cell types, burst-firing neurons, and an epileptogenic subfield. Journal of neurophysiology. vol 56. issue 6. 1987-03-23. PMID:2433411. |
experiments using intracellular chloride (cl-) injection or focal bicuculline application suggested that part of the inhibitory component of the pyramidal cell synaptic response was dependent on a gamma-aminobutyric acid (gaba)-mediated increase in cl- conductance. |
1987-03-23 |
2023-08-11 |
Not clear |
| N R Newberry, R A Nicol. Comparison of the action of baclofen with gamma-aminobutyric acid on rat hippocampal pyramidal cells in vitro. The Journal of physiology. vol 360. 1985-06-13. PMID:3989713. |
application of gaba to the pyramidal cell dendrites evoked, in addition to a depolarization, two types of hyperpolarization. |
1985-06-13 |
2023-08-11 |
rat |
| B E Alger, R A Nicol. Feed-forward dendritic inhibition in rat hippocampal pyramidal cells studied in vitro. The Journal of physiology. vol 328. 1982-12-16. PMID:7131309. |
is produced by gaba released from neuronal elements in the dendritic field which acts on pyramidal cell dendrites.6. |
1982-12-16 |
2023-08-12 |
rat |