| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anton B Tonchev, Tetsumori Yamashima, Liang Zhao, Hideyuki Okan. Differential proliferative response in the postischemic hippocampus, temporal cortex, and olfactory bulb of young adult macaque monkeys. Glia. vol 42. issue 3. 2003-06-10. PMID:12673828. |
the ischemic insult significantly increased the number of proliferating cells in the hippocampus and temporal neocortex, where the majority brdu-labeled cells expressed markers for microglia (iba1, cd68, and ham56) or astrocytes (s-100beta and glial fibrillary acidic protein [gfap]). |
2003-06-10 |
2023-08-12 |
monkey |
| Ikuko Mohri, Naomi Eguchi, Kinuko Suzuki, Yoshihiro Urade, Masako Taniik. Hematopoietic prostaglandin D synthase is expressed in microglia in the developing postnatal mouse brain. Glia. vol 42. issue 3. 2003-06-10. PMID:12673832. |
spaciotemporal evaluation of microglial development and migration with hpgds immunostaining revealed the following three major possible migration pathways of microglia in the postnatal brain: from the lateral ventricle via subventricular zones to brain parenchyma; from the leptomeninges around the cerebellopontine angle to the cerebellar white matter; and from the overlying leptomeninges to the hippocampus, basal forebrain, and brainstem. |
2003-06-10 |
2023-08-12 |
mouse |
| C K Petito, B Adkins, M McCarthy, B Roberts, I Khami. CD4+ and CD8+ cells accumulate in the brains of acquired immunodeficiency syndrome patients with human immunodeficiency virus encephalitis. Journal of neurovirology. vol 9. issue 1. 2003-05-09. PMID:12587067. |
monocytes, microglia, and multinucleated giant cells were immunoreactive for cd4 in aids cases with hippocampal hive but microglia in remaining aids cases and controls were cd4-. |
2003-05-09 |
2023-08-12 |
human |
| C Ananth, P Gopalakrishnakone, C Kau. Induction of inducible nitric oxide synthase expression in activated microglia following domoic acid (DA)-induced neurotoxicity in the rat hippocampus. Neuroscience letters. vol 338. issue 1. 2003-04-10. PMID:12565138. |
induction of inducible nitric oxide synthase expression in activated microglia following domoic acid (da)-induced neurotoxicity in the rat hippocampus. |
2003-04-10 |
2023-08-12 |
rat |
| C Ananth, P Gopalakrishnakone, C Kau. Induction of inducible nitric oxide synthase expression in activated microglia following domoic acid (DA)-induced neurotoxicity in the rat hippocampus. Neuroscience letters. vol 338. issue 1. 2003-04-10. PMID:12565138. |
neuronal degeneration followed by glial activation (microglia and astrocytes) and nitric oxide synthase (nos) expression in the hippocampus was investigated at 3 months after domoic acid (da) administration and compared with da treated rats at 5 days time interval which was reported earlier. |
2003-04-10 |
2023-08-12 |
rat |
| Lary C Walker, Michael J Callahan, Feng Bian, Robert A Durham, Alex E Roher, William J Lipinsk. Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice. Peptides. vol 23. issue 7. 2003-04-03. PMID:12128081. |
five months following injection of ad-extract, an isolated cluster of abeta-immunoreactive microglia was sometimes evident in the ipsilateral entorhinal cortex; the strong innervation of the hippocampus by entorhinal cortical neurons suggests the possible spread of seeded pathology from the injection site via neuronal transport mechanisms. |
2003-04-03 |
2023-08-12 |
mouse |
| Karin Schüppel, Kurt Brauer, Wolfgang Härtig, Jens Grosche, Bernadette Earley, Brian E Leonard, Gert Brückne. Perineuronal nets of extracellular matrix around hippocampal interneurons resist destruction by activated microglia in trimethyltin-treated rats. Brain research. vol 958. issue 2. 2003-03-27. PMID:12470883. |
perineuronal nets of extracellular matrix around hippocampal interneurons resist destruction by activated microglia in trimethyltin-treated rats. |
2003-03-27 |
2023-08-12 |
rat |
| Asha Naidu, Qiang Xu, Rosanne Catalano, Barbara Cordel. Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468034. |
we determined that protein prenylation is required for apoe release from a continuous microglial cell line, primary mixed glia, and from organotypic hippocampal cultures. |
2003-02-25 |
2023-08-12 |
Not clear |
| Chun Shu Piao, Yongzhe Che, Pyung-Lim Han, Ja-Kyeong Le. Delayed and differential induction of p38 MAPK isoforms in microglia and astrocytes in the brain after transient global ischemia. Brain research. Molecular brain research. vol 107. issue 2. 2003-02-10. PMID:12425942. |
the induced p38alpha was concentrated in microglia in hippocampus as well as in frontal and parietal cortices of the brain, where significant neuronal damage was occurred. |
2003-02-10 |
2023-08-12 |
Not clear |
| A D Rogove, W Lu, Stella E Tsirk. Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration. Cell death and differentiation. vol 9. issue 8. 2003-01-31. PMID:12107823. |
we have reported that microglia can exhibit neurotoxic behaviors after injection of excitotoxins into the hippocampus. |
2003-01-31 |
2023-08-12 |
mouse |
| Sheila M Brooke, Robert M Sapolsk. Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia. Experimental neurology. vol 177. issue 1. 2002-12-09. PMID:12429218. |
there also appeared to be a component of gp120 neurotoxicity in hippocampal cultures that was exacerbated by gcs, independent of the amount of microglia present. |
2002-12-09 |
2023-08-12 |
Not clear |
| S Chirumamilla, D Sun, M R Bullock, R J Colell. Traumatic brain injury induced cell proliferation in the adult mammalian central nervous system. Journal of neurotrauma. vol 19. issue 6. 2002-09-13. PMID:12165131. |
in contrast, there was a significant increase in the number of immature astrocytes and activated microglia, but not neurons, at this early time point in the hippocampus. |
2002-09-13 |
2023-08-12 |
rat |
| O T Wolf, V Dyakin, A Patel, C Vadasz, M J de Leon, B S McEwen, K Bulloc. Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment. Brain research. vol 934. issue 2. 2002-08-07. PMID:11955471. |
the histological observations supported the mri data showing neuronal loss and neuronal degeneration in ca1 and ca3 of the hippocampus, which was accompanied by strong microglia activation. |
2002-08-07 |
2023-08-12 |
rat |
| Valerie A M Vincent, Simon P Selwood, Greer M Murph. Proinflammatory effects of M-CSF and A beta in hippocampal organotypic cultures. Neurobiology of aging. vol 23. issue 3. 2002-06-14. PMID:11959396. |
induction of cytokines and inos was also observed after lipopolysaccharide treatment of organotypic hippocampal cultures, but inos expression was localized mainly to microglia rather than astrocytes. |
2002-06-14 |
2023-08-12 |
Not clear |
| G Jean Harry, Kelly Tyler, Christian Lefebvre d'Hellencourt, Hugh A Tilson, William E Maie. Morphological alterations and elevations in tumor necrosis factor-alpha, interleukin (IL)-1alpha, and IL-6 in mixed glia cultures following exposure to trimethyltin: modulation by proinflammatory cytokine recombinant proteins and neutralizing antibodies. Toxicology and applied pharmacology. vol 180. issue 3. 2002-06-11. PMID:12009860. |
trimethyltin (tmt), is a hippocampal neurotoxicant characterized by neuronal degeneration, astrogliosis, and microglia reactivity with an associated elevation in proinflammatory cytokine mrna levels. |
2002-06-11 |
2023-08-12 |
Not clear |
| Gigliola Grassi Zucconi, Maria Assunta Laurenzi, Massimo Semprevivo, Federica Torni, Jan Ake Lindgren, Eva Marinucc. Microglia activation and cell death in response to diethyl-dithiocarbamate acute administration. The Journal of comparative neurology. vol 446. issue 2. 2002-05-09. PMID:11932932. |
administration of ddtc at two different doses, microglia were already activated in selected areas of the rat brain (hippocampal dentate gyrus, entorhinal-pyriform cortex and hypothalamus) after 1 hour, reaching a peak at 3-6 hours and subsided within 6-48 hours, depending on the brain region. |
2002-05-09 |
2023-08-12 |
rat |
| M J Picklo, S J Olson, J D Hayes, W R Markesbery, T J Montin. Elevation of AKR7A2 (succinic semialdehyde reductase) in neurodegenerative disease. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597610. |
our results show that in the cerebral cortex and hippocampus, akr7a2 is primarily localized to glial cells, astrocytes and microglia. |
2002-01-14 |
2023-08-12 |
Not clear |
| L C Park, H Zhang, G E Gibso. Co-culture with astrocytes or microglia protects metabolically impaired neurons. Mechanisms of ageing and development. vol 123. issue 1. 2002-01-04. PMID:11640948. |
td primary hippocampal neurons were either cultured alone, or co-cultured with primary astrocytes or microglia. |
2002-01-04 |
2023-08-12 |
Not clear |
| M R Dandrea, P A Reiser, N A Gumula, B M Hertzog, P Andrade-Gordo. Application of triple immunohistochemistry to characterize amyloid plaque-associated inflammation in brains with Alzheimer's disease. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 76. issue 2. 2001-12-04. PMID:11440311. |
we used our routine single immunohistochemical (ihc) labeling protocol to label amyloid plaques, an ad neuropathological hallmark, activated microglia, and reactive astrocytes in serial sections of ad hippocampus and entorhinal cortex of brain. |
2001-12-04 |
2023-08-12 |
Not clear |
| M R Dandrea, P A Reiser, N A Gumula, B M Hertzog, P Andrade-Gordo. Application of triple immunohistochemistry to characterize amyloid plaque-associated inflammation in brains with Alzheimer's disease. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 76. issue 2. 2001-12-04. PMID:11440311. |
because serial sectioning limited our ability to confirm these findings, we developed a triple ihc protocol to investigate the association of activated microglia and reactive astrocytes simultaneously with amyloid plaques in sections of ad brain entorhinal cortex and hippocampus. |
2001-12-04 |
2023-08-12 |
Not clear |