Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
L F Lue, D G Walker, L Brachova, T G Beach, J Rogers, A M Schmidt, D M Stern, S D Ya. Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism. Experimental neurology. vol 171. issue 1. 2001-10-11. PMID:11520119. |
using brain tissue from ad and nondemented (nd) individuals, rage expression was shown to be present on microglia and neurons of the hippocampus, entorhinal cortex, and superior frontal gyrus. |
2001-10-11 |
2023-08-12 |
Not clear |
X R Lu, W Y On. Heme oxgenase-1 is expressed in viable astrocytes and microglia but in degenerating pyramidal neurons in the kainate-lesioned rat hippocampus. Experimental brain research. vol 137. issue 3-4. 2001-10-04. PMID:11355387. |
heme oxgenase-1 is expressed in viable astrocytes and microglia but in degenerating pyramidal neurons in the kainate-lesioned rat hippocampus. |
2001-10-04 |
2023-08-12 |
rat |
O M Mitrasinovic, G V Perez, F Zhao, Y L Lee, C Poon, G M Murph. Overexpression of macrophage colony-stimulating factor receptor on microglial cells induces an inflammatory response. The Journal of biological chemistry. vol 276. issue 32. 2001-09-06. PMID:11387343. |
by using a co-culture of c-fms-transfected murine microglia and rat organotypic hippocampal slices and a species-specific real time reverse transcriptase-polymerase chain reaction assay and enzyme-linked immunosorbent assay, we showed that m-csfr overexpression on exogenous microglia induced expression of interleukin-1alpha by the organotypic culture. |
2001-09-06 |
2023-08-12 |
mouse |
Y Taniwak. [The microglial activation and the expression of heat shock protein 27 through the propagation pathway of kainic acid-induced hippocampal seizure in the rat]. Fukuoka igaku zasshi = Hukuoka acta medica. vol 92. issue 2. 2001-07-12. PMID:11280925. |
we studied activation of microglia and expression of the 27 kda heat shock protein (hsp27) in the brain during kainic acid-induced acute hippocampal seizures in rats. |
2001-07-12 |
2023-08-12 |
rat |
J Bu, N Akhtar, A Nishiyam. Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion. Glia. vol 34. issue 4. 2001-07-12. PMID:11360302. |
changes in ng2+ cells were examined in kainic acid-induced excitotoxic lesions of the hippocampus, and the relationship between ng2+ cells and reactive astrocytes and microglia was investigated between 1 and 90 days after lesioning. |
2001-07-12 |
2023-08-12 |
Not clear |
E Aronica, B Yankaya, D Troost, E A van Vliet, F H Lopes da Silva, J A Gorte. Induction of neonatal sodium channel II and III alpha-isoform mRNAs in neurons and microglia after status epilepticus in the rat hippocampus. The European journal of neuroscience. vol 13. issue 6. 2001-06-21. PMID:11285025. |
induction of neonatal sodium channel ii and iii alpha-isoform mrnas in neurons and microglia after status epilepticus in the rat hippocampus. |
2001-06-21 |
2023-08-12 |
rat |
K Palin, F Pousset, D Verrier, R Dantzer, K Kelley, P Parnet, J Lestag. Characterization of interleukin-1 receptor antagonist isoform expression in the brain of lipopolysaccharide-treated rats. Neuroscience. vol 103. issue 1. 2001-05-24. PMID:11311797. |
double immunofluorescence staining revealed interleukin-1 receptor antagonist positive neurons and microglia in hippocampus 24h after lipopolysaccharide stimulation. |
2001-05-24 |
2023-08-12 |
rat |
C K Petito, B Roberts, J D Cantando, A Rabinstein, R Dunca. Hippocampal injury and alterations in neuronal chemokine co-receptor expression in patients with AIDS. Journal of neuropathology and experimental neurology. vol 60. issue 4. 2001-04-19. PMID:11305873. |
hive cases had increased neuronal cxcr4 and decreased neuronal ccr5 expression as well as increased numbers of hippocampal gfap-positive astrocytes and ln3-positive microglia. |
2001-04-19 |
2023-08-12 |
Not clear |
P J Kingham, J M Pococ. Microglial secreted cathepsin B induces neuronal apoptosis. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238732. |
conditioned medium from cga exposed microglia was neurotoxic to the ht22 hippocampal cell line and to primary cultures of cerebellar granule neurones. |
2001-04-05 |
2023-08-12 |
Not clear |
H J Bidmon, B Emde, E Oermann, R Kubitz, O W Witte, K Zille. Heme oxygenase-1 (HSP-32) and heme oxygenase-2 induction in neurons and glial cells of cerebral regions and its relation to iron accumulation after focal cortical photothrombosis. Experimental neurology. vol 168. issue 1. 2001-03-29. PMID:11170717. |
ho-1-positive astrocytes and microglia occurred in ipsilateral cortex, corpus callosum, hippocampus, striatum, and thalamic nuclei. |
2001-03-29 |
2023-08-12 |
rat |
S W Barger, A S Basil. Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function. Journal of neurochemistry. vol 76. issue 3. 2001-03-15. PMID:11158256. |
conditioned medium from primary rat microglia activated by sapp caused a calcium elevation in hippocampal neurons, whereas medium from untreated microglia did not. |
2001-03-15 |
2023-08-12 |
rat |
C Eriksson, L P Zou, S Ahlenius, B Winblad, M Schultzber. Inhibition of kainic acid induced expression of interleukin-1 beta and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146112. |
results in a transient expression of il-1 beta and il-1ra mrna, mainly in microglia, in regions showing neurodegeneration such as the hippocampus, thalamus, amygdala, and certain cortical regions. |
2001-03-08 |
2023-08-12 |
rat |
S E Arnold, L Y Han, C M Clark, M Grossman, J Q Trojanowsk. Quantitative neurohistological features of frontotemporal degeneration. Neurobiology of aging. vol 21. issue 6. 2001-02-15. PMID:11124442. |
we found that ftd frontal and hippocampal regions exhibited marked neuron loss, abundant ubiquitin-immunoreactive (ir) dystrophic neurites, gfap-ir astrocytes, and cd68-ir microglia, while calcarine cortex was spared. |
2001-02-15 |
2023-08-12 |
human |
D Koczyk, B Oderfeld-Nowa. Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 6. 2000-09-28. PMID:10884604. |
long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of ngf and trka immunoreactivities in astroglia but not in microglia. |
2000-09-28 |
2023-08-12 |
rat |
E Aronica, E A van Vliet, O A Mayboroda, D Troost, F H da Silva, J A Gorte. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. The European journal of neuroscience. vol 12. issue 7. 2000-09-19. PMID:10947812. |
se resulted in hypertrophy of astrocytes and microglia activation throughout the hippocampus as revealed by immunolabelling studies. |
2000-09-19 |
2023-08-12 |
rat |
M B Jensen, I V Hegelund, N D Lomholt, B Finsen, T Owen. IFNgamma enhances microglial reactions to hippocampal axonal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 10. 2000-05-25. PMID:10804203. |
we have studied activation of hippocampal microglia to produce tnfalpha in response to transection of perforant path axons in sjl/j mice. |
2000-05-25 |
2023-08-12 |
mouse |
B Hauss-Wegrzyniak, M G Vannucchi, G L Wen. Behavioral and ultrastructural changes induced by chronic neuroinflammation in young rats. Brain research. vol 859. issue 1. 2000-05-09. PMID:10720625. |
immunohistochemical staining found numerous highly activated microglia distributed throughout the cingulate gyrus, entorhinal cortex, hippocampus and dentate gyrus. |
2000-05-09 |
2023-08-12 |
rat |
G G Skibo, I R Nikonenko, V L Savchenko, J A McKann. Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683583. |
microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. |
2000-04-20 |
2023-08-12 |
Not clear |
G G Skibo, I R Nikonenko, V L Savchenko, J A McKann. Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683583. |
lipocortin-1 immunocytochemistry was used to study the various cell forms of microglia that appear during organotypic hippocampal tissue culture, as well as in the in vitro toxic hypoxia model. |
2000-04-20 |
2023-08-12 |
Not clear |
V Zujovic, J Benavides, X Vigé, C Carter, V Taupi. Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation. Glia. vol 29. issue 4. 2000-04-11. PMID:10652441. |
lps-activated microglia were neurotoxic when added to neuronal hippocampal culture, producing 20% neuronal death, as measured by neun-positive cell counting. |
2000-04-11 |
2023-08-12 |
rat |