| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessia Cavallo, Wolf-Julian Neuman. Dopaminergic reinforcement in the motor system: Implications for Parkinson's disease and deep brain stimulation. The European journal of neuroscience. 2024-01-05. PMID:38178558. |
the canonical circuit architecture of cortico-striatal loops sparks the question, of whether dopamine signals in the basal ganglia serve an overarching computational principle. |
2024-01-05 |
2024-01-07 |
human |
| Oliver D Howes, Bernard R Bukala, Katherine Bec. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nature reviews. Neurology. 2023-12-19. PMID:38110704. |
this evidence demonstrates regionally specific neurotransmitter alterations, including higher glutamate and dopamine measures in the basal ganglia, and lower glutamate, dopamine and γ-aminobutyric acid (gaba) levels in cortical regions, particularly the frontal cortex, relative to healthy individuals. |
2023-12-19 |
2023-12-21 |
Not clear |
| Narmadhaa Sivagurunathan, Mohamudha Parveen Rahamathulla, Hussein Al-Dossary, Latchoumycandane Calivaratha. Emerging Role of Long Noncoding RNAs in Regulating Inflammasome-Mediated Neurodegeneration in Parkinson's Disease. Molecular neurobiology. 2023-12-17. PMID:38105409. |
the underlying pathophysiology involves the progressive loss of dopaminergic neurons within the substantia nigra pars compacta, leading to dopamine depletion in the basal ganglia circuitry. |
2023-12-17 |
2023-12-21 |
Not clear |
| Sandra Romero Pinto, Naoshige Uchid. Tonic dopamine and biases in value learning linked through a biologically inspired reinforcement learning model. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014087. |
our model provides a foundation for understanding the basal ganglia circuit and underscores the significance of tonic dopamine in modulating learning processes. |
2023-11-28 |
2023-11-29 |
mouse |
| Rafael Rivas-Santisteban, Alberto Rico, Ana Muñoz, Ana I Rodriguez, Irene Reyes-Resina, Gemma Navarro, José Luis Labandeira-García, José Luis Lanciego, Rafael Franc. Boolean analysis shows a high proportion of dopamine D Neurobiology of disease. 2023-11-02. PMID:37918757. |
boolean analysis shows a high proportion of dopamine d the antagonistic effect of adenosine on dopaminergic transmission in the basal ganglia indirect motor control pathway is mediated by dopamine d |
2023-11-02 |
2023-11-08 |
Not clear |
| Maxwell J Wagner, Charles P Daniel, Connor J Plaisance, Grant E Borne, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kay. Apomorphine for Parkinson's disease: pharmacologic and clinical considerations. Expert opinion on emerging drugs. 2023-11-01. PMID:37909462. |
in parkinson's disease, dopamine depletion in the basal ganglia leads to symptoms including bradykinesia, gait abnormalities, and cognitive impairment. |
2023-11-01 |
2023-11-08 |
Not clear |
| Saverio La Bella, Giovanna Scorrano, Marta Rinaldi, Armando Di Ludovico, Francesca Mainieri, Marina Attanasi, Alberto Spalice, Francesco Chiarelli, Luciana Bred. Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS): Myth or Reality? The State of the Art on a Controversial Disease. Microorganisms. vol 11. issue 10. 2023-10-30. PMID:37894207. |
recent advances in the comprehension of pandas pathophysiology are largely attributable to animal model studies and the understanding of the roles of ca++/calmodulin-dependent protein kinase (cam kinase) ii, disrupted dopamine release in the basal ganglia, and striatal cholinergic interneurons. |
2023-10-30 |
2023-11-08 |
Not clear |
| Talifu Zikereya, Kaixuan Shi, Wei Che. Goal-directed and habitual control: from circuits and functions to exercise-induced neuroplasticity targets for the treatment of Parkinson's disease. Frontiers in neurology. vol 14. 2023-10-26. PMID:37881310. |
the progressive depletion of dopamine (da) is the pathological basis of dysfunctional goal-directed and habitual control circuits in the basal ganglia. |
2023-10-26 |
2023-11-08 |
Not clear |
| Chang Li, Osama F Elabi, Tim Fieblinger, M Angela Cenc. Structural-functional properties of direct-pathway striatal neurons at early and chronic stages of dopamine denervation. The European journal of neuroscience. 2023-10-25. PMID:37876330. |
the dendritic arbour of striatal projection neurons (spns) is the primary anatomical site where dopamine and glutamate inputs to the basal ganglia functionally interact to control movement. |
2023-10-25 |
2023-11-08 |
mouse |
| Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
while our understanding of dopamine (da)'s role in modulating striatal circuitry has deepened in recent years, it also has become clear that it acts in other regions of the basal ganglia to influence movement. |
2023-10-22 |
2023-11-08 |
mouse |
| Pol Bech, Sylvain Crochet, Robin Dard, Parviz Ghaderi, Yanqi Liu, Meriam Malekzadeh, Carl C H Petersen, Mauro Pulin, Anthony Renard, Christos Sourmpi. Striatal Dopamine Signals and Reward Learning. Function (Oxford, England). vol 4. issue 6. 2023-10-16. PMID:37841525. |
neuronal circuits of the basal ganglia have been strongly implicated in action selection, as well as the learning and execution of goal-directed behaviors, with accumulating evidence supporting the hypothesis that midbrain dopamine neurons might encode a reward signal useful for learning. |
2023-10-16 |
2023-11-08 |
Not clear |
| Kelsey Barcomb, Christopher P For. Alterations in neurotransmitter co-release in Parkinson's disease. Experimental neurology. 2023-10-06. PMID:37802381. |
parkinson's disease is a neurological disorder characterized by degeneration of midbrain dopamine neurons, which results in numerous adaptations in basal ganglia circuits. |
2023-10-06 |
2023-10-15 |
Not clear |
| Dimitri Ryczko, Réjean Dubu. Dopamine control of downstream motor centers. Current opinion in neurobiology. vol 83. 2023-09-29. PMID:37774481. |
the role of dopamine in the control of movement is traditionally associated with ascending projections to the basal ganglia. |
2023-09-29 |
2023-10-07 |
Not clear |
| Victor Pando-Naude, Tomas Edward Matthews, Andreas Højlund, Sebastian Jakobsen, Karen Østergaard, Erik Johnsen, Eduardo A Garza-Villarreal, Maria A G Witek, Virginia Penhune, Peter Vuus. Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms. The European journal of neuroscience. 2023-09-19. PMID:37724707. |
dopamine in motor and limbic networks is implicated in beat-based timing and music-induced pleasure, suggesting a central role of basal ganglia (bg) dopaminergic systems in plumm. |
2023-09-19 |
2023-10-07 |
human |
| Alain Rios, Satoshi Nonomura, Shigeki Kato, Junichi Yoshida, Natsuki Matsushita, Atsushi Nambu, Masahiko Takada, Riichiro Hira, Kazuto Kobayashi, Yutaka Sakai, Minoru Kimura, Yoshikazu Isomur. Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways. Communications biology. vol 6. issue 1. 2023-09-06. PMID:37673949. |
given the classical basal ganglia model wherein dopamine stimulates dspns and suppresses ispns through distinct dopamine receptors, dopamine might not be the primary driver of ispn activity increasing following higher reward expectation. |
2023-09-06 |
2023-10-07 |
rat |
| Oleg Tolstenkov, Yana Mikhaleva, Joel C Glove. A miniaturized nigrostriatal-like circuit regulating locomotor performance in a protochordate. Current biology : CB. 2023-08-29. PMID:37643617. |
the circuit is reminiscent of the nigrostriatopallidal system in the vertebrate basal ganglia, in which disinhibitory circuits release specific movements under the modulatory control of dopamine. |
2023-08-29 |
2023-09-07 |
Not clear |
| Véronique Coizet, Racha Al Tannir, Arnaud Pautrat, Paul G Overto. Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures. Current neuropharmacology. 2023-08-18. PMID:37594168. |
this function relies on afferents targeting the main input structures of the basal ganglia, entering bids for action selection at the level of the striatum or sig- nals for behavioral interruption at the level of the subthalamic nucleus, with behavioral reselection facilitated by dopamine signaling. |
2023-08-18 |
2023-09-07 |
Not clear |
| Emil Wärnberg, Arvind Kuma. Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 32. 2023-08-01. PMID:37527344. |
feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. |
2023-08-01 |
2023-08-14 |
Not clear |
| Rupsha Mondal, Chayan Banerjee, Sumangal Nandy, Moumita Roy, Joy Chakrabort. Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson's disease model. Cell & bioscience. vol 13. issue 1. 2023-08-01. PMID:37528492. |
this leads to depleted dopamine (da) content at striatum, thus affecting the fine tuning of basal ganglia. |
2023-08-01 |
2023-08-14 |
Not clear |
| Michael B Prit. Nuclei and tracts in the epithalamus of crocodiles. The Journal of comparative neurology. 2023-07-29. PMID:37507852. |
the medial component is related to the limbic system and serotonergic raphe, while the lateral nucleus is more interconnected with the basal ganglia and midbrain dopamine systems. |
2023-07-29 |
2023-08-14 |
Not clear |