| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P M Pitychoutis, C Dalla, A C Sideris, P A Tsonis, Z Papadopoulou-Daifot. 5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. Neuroscience. vol 210. 2012-09-21. PMID:22441040. |
cms and clomipramine treatment induced sex-differentiated effects on rats' hedonic status and enhanced 5-ht(1a)r mrna expression in the cornu ammonis 1 (ca1) hippocampal region of male rats. |
2012-09-21 |
2023-08-12 |
rat |
| E Soleimannejad, N Naghdi, Sh Khatami, S Semnanian, Y Fathollah. Formalin pain increases the concentration of serotonin and its 5-hydroxyindoleacetic acid metabolite in the CA1 region of hippocampus. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. vol 18. issue 1. 2012-08-23. PMID:22615590. |
formalin pain increases the concentration of serotonin and its 5-hydroxyindoleacetic acid metabolite in the ca1 region of hippocampus. |
2012-08-23 |
2023-08-12 |
Not clear |
| P Panther, S Nullmeier, H Dobrowolny, H Schwegler, R Wol. CPB-K mice a mouse model of schizophrenia? Differences in dopaminergic, serotonergic and behavioral markers compared to BALB/cJ mice. Behavioural brain research. vol 230. issue 1. 2012-07-23. PMID:22454846. |
our results can be summarized as follows: compared to balb/cj, cpb-k mice showed:(1) significantly reduced traveling distance and number of contacts in social interaction test, (2) differences in the number of serotonin transporter-immunoreactive neurons and volume of raphe nuclei and a lower serotonergic fiber density in the ventral and dorsal hippocampal subfields ca1 and ca3, (3) no alterations of dopaminergic markers like neuron number, neuron density and volume in subregions of substantia nigra and ventral tegmental area, but a significantly higher dopaminergic fiber density in the dorsal hippocampus, the ventral hippocampus of ca1 and gyrus dentatus, (4) no significant differences in serotonergic and dopaminergic fiber densities in the amygdala.based on our results and previous studies, cpb-k mice compared to balb/cj may serve as an important model to understand the interaction of the serotonergic and dopaminergic system and their impact on sensorimotor gating and cognitive function as related to neuropsychiatric disorders like schizophrenia. |
2012-07-23 |
2023-08-12 |
mouse |
| Alexander K Converse, Yves Aubert, Mohammed Farhoud, Jamey P Weichert, Ian J Rowland, Nicole M Ingrisano, Kelly A Allers, Bernd Sommer, David H Abbot. Positron emission tomography assessment of 8-OH-DPAT-mediated changes in an index of cerebral glucose metabolism in female marmosets. NeuroImage. vol 60. issue 1. 2012-07-03. PMID:22233732. |
we hypothesized that chronic treatment with the 5-ht(1a) agonist 8-oh-dpat would alter the glucose metabolism index in dorsal raphe (dr), medial prefrontal cortex (mpfc), medial preoptic area of hypothalamus (mpoa), ventromedial nucleus of hypothalamus (vmh), and field ca1 of hippocampus. |
2012-07-03 |
2023-08-12 |
human |
| K Tokarski, M Kusek, G Hes. 5-HT7 receptors modulate GABAergic transmission in rat hippocampal CA1 area. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 62. issue 5. 2012-06-25. PMID:22204801. |
the effects of the activation of serotonin-7 (5-ht(7)) receptors were investigated in the ca1 area pyramidal cells and stratum radiatum fast spiking gabaergic interneurons of rat hippocampal slices. |
2012-06-25 |
2023-08-12 |
rat |
| K Tokarski, M Kusek, G Hes. 5-HT7 receptors modulate GABAergic transmission in rat hippocampal CA1 area. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 62. issue 5. 2012-06-25. PMID:22204801. |
these data suggest that the activation of 5-ht(7) receptors results in an enhancement of the gabaergic transmission in the hippocampal ca1 area via two mechanisms. |
2012-06-25 |
2023-08-12 |
rat |
| Marisa Soledad Ghersi, Sebastian M Casas, Carla Escudero, Valeria P Carlini, Florencia Buteler, Ricardo J Cabrera, Helgi B Schiöth, Susana R de Bariogli. Ghrelin inhibited serotonin release from hippocampal slices. Peptides. vol 32. issue 11. 2012-04-16. PMID:21820473. |
in another set of experiments, ghr was infused into the ca1 area of hippocampus of the rats immediately after training in the step down test and the 5-ht release from slices was studied 24h after ghr injection showing that in this condition also the 5-ht release was inhibited (h = 11.72, df = 1, p ≤ 0.05). |
2012-04-16 |
2023-08-12 |
rat |
| Enrique Jiménez-Ferrer, Maribel Herrera-Ruiz, Raúl Ramírez-García, Armando Herrera-Arellano, Jaime Tortoriell. Interaction of the natural anxiolytic Galphimine-B with serotonergic drugs on dorsal hippocampus in rats. Journal of ethnopharmacology. vol 137. issue 1. 2011-12-27. PMID:21742023. |
for this reason, the objective of this work was to evaluate the pharmacological interaction between g-b with the 5-hydroxytryptamine 1a (5ht(1a)) and 5-hydroxytryptamine 2a (5ht(2a)) serotonergic receptors on ca1 neurons of hippocampus. |
2011-12-27 |
2023-08-12 |
rat |
| H N Noristani, R S Meadows, M Olabarria, A Verkhratsky, J J Rodrígue. Increased hippocampal CA1 density of serotonergic terminals in a triple transgenic mouse model of Alzheimer's disease: an ultrastructural study. Cell death & disease. vol 2. 2011-11-28. PMID:21918544. |
we recently demonstrated an increase in 5-ht transporter (sert) fibre density in the hippocampal ca1 in an ad triple transgenic mouse model (3xtg-ad). |
2011-11-28 |
2023-08-12 |
mouse |
| Martin Egeland, Jennifer Warner-Schmidt, Paul Greengard, Per Svenningsso. Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum. Neuropharmacology. vol 61. issue 3. 2011-10-14. PMID:21300076. |
in the caudate-putamen, the hippocampal pyramidal cell layer of ca1 and the hippocampal granule cell layer of dentate gyrus, most p11 containing cells co-expressed both 5-ht(1b)r and 5-ht(4)r. in the cingulate cortex, stratum radiatum/oriens of ca1, hilus of the dentate gyrus and cerebellar cortex, many cells co-expressed p11 and 5-ht(1b)r, but not 5-ht(4)r. in the studied brain regions, few cells solely expressed p11 without any significant expression of 5-ht(1b)r or 5-ht(4)r. it can be concluded that p11 is anatomically positioned to modulate serotonin neurotransmission, via 5-ht(1b)r and 5-ht(4)r, in brain regions important for emotionality, cognition and locomotion. |
2011-10-14 |
2023-08-12 |
mouse |
| Jochen Winterer, A Vanessa Stempel, Tamar Dugladze, Csaba Földy, Nino Maziashvili, Aleksandar R Zivkovic, Josef Priller, Ivan Soltesz, Tengis Gloveli, Dietmar Schmit. Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 23. 2011-09-01. PMID:21653851. |
here we show that serotonin via 5-ht(1b) heteroreceptors substantially reduces synaptic excitation of cholecystokinin-expressing interneurons in area ca1 of the rat hippocampus, in contrast to parvalbumin-expressing basket cells. |
2011-09-01 |
2023-08-12 |
rat |
| Emily Freeman-Daniels, Sheryl G Beck, Lynn G Kirb. Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice. Psychopharmacology. vol 213. issue 2-3. 2011-05-24. PMID:20981413. |
tissue-specific "rescue" strategies and electrophysiology have implicated a critical role for postsynaptic 5-ht(1a) receptors, particularly in the ca1 region of the hippocampus. |
2011-05-24 |
2023-08-12 |
mouse |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
hippocampal serotonin depletion facilitates place learning concurrent with an increase in ca1 high frequency theta activity expression in the rat. |
2011-04-18 |
2023-08-12 |
rat |
| Blanca Erika Gutiérrez-Guzmán, J Jesús Hernández-Pérez, Ignacio González-Burgos, Alfredo Feria-Velásco, Rafael Medina, Miguel Ángel Guevara, Miguel Ángel López-Vázquez, María Esther Olvera-Corté. Hippocampal serotonin depletion facilitates place learning concurrent with an increase in CA1 high frequency theta activity expression in the rat. European journal of pharmacology. vol 652. issue 1-3. 2011-04-18. PMID:21118676. |
following 5-ht hippocampal depletion through 5,7-dihydroxytriptamine-induced lesions to the fimbria, fornix and cingulate bundle of adult rats, ca1 hippocampal theta activity was recorded during place learning training. |
2011-04-18 |
2023-08-12 |
rat |
| Hideo Suzuki, S Duke Han, Louis R Luca. Increased 5-HT1B receptor density in the basolateral amygdala of passive observer rats exposed to aggression. Brain research bulletin. vol 83. issue 1-2. 2011-02-14. PMID:20599596. |
it was hypothesized that passive exposure to aggression for 23 consecutive days would result in altered 5-ht(1b) receptor densities in the ventromedial hypothalamus, medial amygdaloid nucleus, ca1 of the hippocampus, globus pallidus, dentate gyrus, and/or basolateral amygdala. |
2011-02-14 |
2023-08-12 |
rat |
| H N Noristani, M Olabarria, A Verkhratsky, J J Rodrígue. Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20576032. |
serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the ca1 area of hippocampus in a triple transgenic mouse model of alzheimer's disease. |
2011-01-13 |
2023-08-12 |
mouse |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
an exacerbated age-related loss of serotonin fiber density specific for the ca1 area was observed in the clh animals, whereas reduced hippocampal bdnf levels were seen in young and old clh when compared with age-matched cnlh controls. |
2010-09-08 |
2023-08-12 |
rat |
| P J West, V R Marcy, M J Marino, H Schaffhause. Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19660530. |
in the present study, selective pharmacological tools were employed to determine the effect of 5-ht(6) receptor activation on long-term potentiation (ltp) in brain slices containing area ca1 of the hippocampus. |
2010-02-12 |
2023-08-12 |
rat |
| P J West, V R Marcy, M J Marino, H Schaffhause. Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19660530. |
taken together, these results suggest that the 5-ht(6) receptor plays a role in the modulation of synaptic plasticity in hippocampal area ca1 and that the regulation of gabaergic interneuron activity may underlie the cognition enhancing effects of 5-ht(6) antagonists. |
2010-02-12 |
2023-08-12 |
rat |
| I G Sil'ki. Characteristics of the functioning of the hippocampal formation in waking and paradoxical sleep. Neuroscience and behavioral physiology. vol 39. issue 6. 2009-08-27. PMID:19513850. |
analysis of published data identifying different neurotransmitter concentrations in the brain in paradoxical sleep and waking and data on the influences of neurotransmitters on the efficiency of the synaptic inputs to hippocampal neurons led to the conclusion that increases in the acetylcholine, cortisol, and dopamine concentrations during paradoxical sleep, with simultaneous reductions in serotonin and noradrenaline levels, may lead synergistically to a significant depression of transmission efficiency in polysynaptic pathways running through the hippocampus (i.e., the perforant path to neurons of the dentate gyrus, the pathway from the dentate gyrus to field ca3, from field ca3 to field ca1, and from field ca1 to the subiculum) but also to potentiation of the efficiency of the perforant path to pyramidal neurons of fields ca1 and ca3 and increases in the efficiency of associative connections between neurons in field ca3. |
2009-08-27 |
2023-08-12 |
Not clear |