| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sameh M Farouk, Ahmed M Abdellatif, Elsayed Metwall. Outer and inner mitochondrial membrane proteins TOMM40 and TIMM50 are intensively concentrated and localized at Purkinje and pyramidal neurons in the New Zealand white rabbit brain. Anatomical record (Hoboken, N.J. : 2007). vol 305. issue 1. 2021-12-08. PMID:34041863. |
meanwhile, purkinje cells in the cerebellum and pyramidal neurons in the hippocampus displayed higher intensities in their cytoplasm. |
2021-12-08 |
2023-08-13 |
rabbit |
| Laura Tapella, Giulia Dematteis, Federico Alessandro Ruffinatti, Luisa Ponzoni, Fabio Fiordaliso, Alessandro Corbelli, Enrico Albanese, Beatrice Pistolato, Jessica Pagano, Elettra Barberis, Emilio Marengo, Claudia Balducci, Gianluigi Forloni, Chiara Verpelli, Carlo Sala, Carla Distasi, Mariaelvina Sala, Marcello Manfredi, Armando A Genazzani, Dmitry Li. Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures. Cell calcium. vol 100. 2021-12-07. PMID:34607180. |
here we report that in mice with conditional deletion of can in gfap-expressing astrocytes (astroglial calcineurin ko, acn-ko), at 1 month of age, transcription was largely unchanged, while the proteome was deranged in the hippocampus and cerebellum. |
2021-12-07 |
2023-08-13 |
mouse |
| Daniela Silva Santos, Dirson João Stein, Helouise Richardt Medeiros, Fernanda Dos Santos Pereira, Isabel Cristina de Macedo, Felipe Fregni, Wolnei Caumo, Iraci L S Torre. Transcranial direct current stimulation alters anxious-like behavior and neural parameters in rats with chronic pain exposed to alcohol. Journal of psychiatric research. vol 144. 2021-12-07. PMID:34735841. |
rats were killed 24 h after the last behavioral assessment, and brain and spinal cord tissue samples were collected and processed for npy immunohistochemistry, expression of il1a and il1b in the spinal cord, cerebellum, and hippocampus, and levels of il-1α and il-1β in the same brain structures and the striatum. |
2021-12-07 |
2023-08-13 |
rat |
| C-P Chung, W-J Lee, L-N Peng, H Shimada, T-F Tsai, C-P Lin, H Arai, L-K Che. Physio-Cognitive Decline Syndrome as the Phenotype and Treatment Target of Unhealthy Aging. The journal of nutrition, health & aging. vol 25. issue 10. 2021-12-07. PMID:34866145. |
moreover, pcds is associated with characteristic neuroanatomic changes in the cerebellum and hippocampus, and their neurocircuitry, which are distinct from neuroimaging features in normal aging and common dementia syndromes. |
2021-12-07 |
2023-08-13 |
Not clear |
| Lu Wang, Min Zhang, Jing Wen, Yalan Xiang, Xiaoyu Duan, Changwei Yu, Miao Yan, Bikui Zhang, Pingfei Fan. Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats. Frontiers in pharmacology. vol 12. 2021-12-07. PMID:34867385. |
the concentration of monoamines, amino acids, and choline neurotransmitters, the dopamine (da) and 5-hydroxytryptamine (5-ht) metabolic pathway in the hippocampus, cerebellum, striatum, prefrontal cortex, hypothalamus, serum, and plasma were detected by lc-ms/ms. |
2021-12-07 |
2023-08-13 |
rat |
| Anastasiia Bohush, Agnieszka Góral, Małgorzata Sierant, Barbara Nawrot, Wiesława Leśniak, Anna Filipe. Sgt1 Regulates α-Synuclein Subcellular Localization and Expression of Parkinson's Disease Related Genes, Biomolecules. vol 11. issue 11. 2021-11-30. PMID:34827672. |
sgt1 regulates α-synuclein subcellular localization and expression of parkinson's disease related genes, the sgt1 protein is highly expressed in the mammalian brain, particularly in neurons of the hippocampus and cortex, and in purkinje cells of the cerebellum. |
2021-11-30 |
2023-08-13 |
Not clear |
| Ross Minter, Katheleen J Gardine. Trisomy of Human Chromosome 21 Orthologs Mapping to Mouse Chromosome 10 Cause Age and Sex-Specific Learning Differences: Relevance to Down Syndrome. Genes. vol 12. issue 11. 2021-11-29. PMID:34828303. |
here, we have tested separate cohorts of female and male dp10 mice, at 3 and 9 months of age, in an open field elevated zero maze, rotarod, and balance beam, plus the learning and memory tasks, spontaneous alternation, puzzle box, double-h maze, context fear conditioning, and acoustic startle/prepulse inhibition, that depend upon the function of the prefrontal cortex, striatum, hippocampus, and cerebellum. |
2021-11-29 |
2023-08-13 |
mouse |
| Richard Salvi, Kelly Radziwon, Senthilvelan Manohar, Ben Auerbach, Dalian Ding, Xiaopeng Liu, Condon Lau, Yu-Chen Chen, Guang-Di Che. Review: Neural Mechanisms of Tinnitus and Hyperacusis in Acute Drug-Induced Ototoxicity. American journal of audiology. vol 30. issue 3S. 2021-11-24. PMID:33465315. |
functional imaging studies indicated that salicylate increased spontaneous activity and enhanced functional connectivity between structures in the central auditory pathway and regions of the brain associated with arousal (reticular formation), emotion (amygdala), memory/spatial navigation (hippocampus), motor planning (cerebellum), and motor control (caudate/putamen). |
2021-11-24 |
2023-08-13 |
Not clear |
| Bernardo de Moraes Meine, Natália Pontes Bona, Karina Pereira Luduvico, Luiza Spohr, Nathalia Stark Pedra, Roselia Maria Spanevello, Francieli Moro Stefanello, Mayara Sandrielly Pereira Soare. Acute hypermethioninemia impairs redox homeostasis and acetylcholinesterase activity in the hippocampus, striatum, and cerebellum of young rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 3. 2021-11-24. PMID:33606291. |
acute hypermethioninemia impairs redox homeostasis and acetylcholinesterase activity in the hippocampus, striatum, and cerebellum of young rats. |
2021-11-24 |
2023-08-13 |
rat |
| Bernardo de Moraes Meine, Natália Pontes Bona, Karina Pereira Luduvico, Luiza Spohr, Nathalia Stark Pedra, Roselia Maria Spanevello, Francieli Moro Stefanello, Mayara Sandrielly Pereira Soare. Acute hypermethioninemia impairs redox homeostasis and acetylcholinesterase activity in the hippocampus, striatum, and cerebellum of young rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 81. issue 3. 2021-11-24. PMID:33606291. |
the aim of this study was to analyze the redox status and acetylcholinesterase (ache) activity in the hippocampus, striatum, and cerebellum of young wistar rats subjected to an acute hypermethioninemia protocol. |
2021-11-24 |
2023-08-13 |
rat |
| Aruna Sharma, Lianyuan Feng, Dafin F Muresanu, Seaab Sahib, Z Ryan Tian, José Vicente Lafuente, Anca D Buzoianu, Rudy J Castellani, Ala Nozari, Lars Wiklund, Hari Shanker Sharm. Manganese nanoparticles induce blood-brain barrier disruption, cerebral blood flow reduction, edema formation and brain pathology associated with cognitive and motor dysfunctions. Progress in brain research. vol 265. 2021-11-24. PMID:34560926. |
at this time, bbb disruption, reduction in cerebral blood flow (cbf), brain edema formation and brain pathology were most marked in the sensory-motor cortex, hippocampus, caudate putamen, cerebellum and thalamus followed by hypothalamus, pons, medulla and spinal cord. |
2021-11-24 |
2023-08-13 |
rat |
| M A Gruden, T V Davydova, A M Ratmirov, R D E Sewel. Effects of Antibodies to Glutamate on Cerebral Expression of the Tnfrsf1A Gene under Conditions of Spatial Amnesia Induced by Proinflammatory Protein S100A9 Fibrils in Aging Mice. Bulletin of experimental biology and medicine. vol 172. issue 1. 2021-11-23. PMID:34796426. |
we studied the effects of chronic intranasal administration of in vitro prepared s100a9 fibrils alone or in combination with anti-glutamate antibodies on the expression of the tnfrsf1a gene in the hippocampus, prefrontal cortex, and cerebellum of aging c57bl/6 mice under conditions of impaired spatial memory. |
2021-11-23 |
2023-08-13 |
mouse |
| M A Gruden, T V Davydova, A M Ratmirov, R D E Sewel. Effects of Antibodies to Glutamate on Cerebral Expression of the Tnfrsf1A Gene under Conditions of Spatial Amnesia Induced by Proinflammatory Protein S100A9 Fibrils in Aging Mice. Bulletin of experimental biology and medicine. vol 172. issue 1. 2021-11-23. PMID:34796426. |
a differential cerebral pattern of tnfrsf1a gene activity and its modification by s100a9 fibrillar structures were observed: inhibition of tnfrsf1a gene expression in the hippocampus and cerebellum and its activation in the prefrontal cortex. |
2021-11-23 |
2023-08-13 |
mouse |
| Junhua Wang, Ying Wan. Circular RNA cerebellar degeneration-related protein 1 antisense RNA (Circ-CDR1as) downregulation induced by dexmedetomidine treatment protects hippocampal neurons against hypoxia/reoxygenation injury through the microRNA-28-3p (miR-28-3p)/tumor necrosis factor receptor-associated factor-3 (TRAF3) axis. Bioengineered. 2021-11-17. PMID:34787053. |
circular rna cerebellar degeneration-related protein 1 antisense rna (circ-cdr1as) downregulation induced by dexmedetomidine treatment protects hippocampal neurons against hypoxia/reoxygenation injury through the microrna-28-3p (mir-28-3p)/tumor necrosis factor receptor-associated factor-3 (traf3) axis. |
2021-11-17 |
2023-08-13 |
mouse |
| Amin Haghani, Max Thorwald, Todd E Morgan, Caleb E Finc. The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 2. 2021-11-15. PMID:33215813. |
in humans, the ad vulnerable hippocampus and amygdala had stronger age decline in apoe cluster expression than the ad-resistant cerebellum and hypothalamus. |
2021-11-15 |
2023-08-13 |
mouse |
| Fei-Fei Wu, Kun-Long Zhang, Zheng-Mei Wang, Yi Yang, Shao-Hua Li, Jia-Qi Wang, Jin Ma, Yan-Ling Yang, Hai-Feng Zhang, Ya-Yun Wan. Benefit of a single simulated hypobaric hypoxia in healthy mice performance and analysis of mitochondria-related gene changes. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33627689. |
third, the effects of shh on 8 mitochondria-related genes of drp1, mfn1, mfn2, opa1, tfam, sgk1, ucp2 and ucp4, were assessed in cerebellum, hippocampus and gastrocnemius muscles. |
2021-11-15 |
2023-08-13 |
mouse |
| Víctor Costumero, Patricia Rosell Negre, Juan Carlos Bustamante, Paola Fuentes-Claramonte, Jesús Adrián-Ventura, María-Ángeles Palomar-García, Anna Miró-Padilla, Juan José Llopis, Jorge Sepulcre, Alfonso Barrós-Loscertale. Distance disintegration characterizes node-level topological dysfunctions in cocaine addiction. Addiction biology. vol 26. issue 6. 2021-11-10. PMID:34137121. |
cud individuals as compared with healthy controls showed higher optimal connectivity distances in ventral striatum, insula, cerebellum, temporal cortex, lateral orbitofrontal cortex, middle frontal cortex and left hippocampus. |
2021-11-10 |
2023-08-13 |
human |
| Melissa Scholefield, Stephanie J Church, Jingshu Xu, Stefano Patassini, Federico Roncaroli, Nigel M Hooper, Richard D Unwin, Garth J S Coope. Severe and Regionally Widespread Increases in Tissue Urea in the Human Brain Represent a Novel Finding of Pathogenic Potential in Parkinson's Disease Dementia. Frontiers in molecular neuroscience. vol 14. 2021-11-10. PMID:34751215. |
here we report measurements of tissue urea from nine neuropathologically confirmed regions of the brain in pdd and post-mortem delay (pmd)-matched controls, in regions including the cerebellum, motor cortex (mcx), sensory cortex, hippocampus (hp), substantia nigra (sn), middle temporal gyrus (mtg), medulla oblongata (med), cingulate gyrus, and pons, by applying ultra-high-performance liquid chromatography-tandem mass spectrometry (uhplc-ms/ms). |
2021-11-10 |
2023-08-13 |
human |
| Haidong Xu, Xiaolei Liu, Wenming Li, Ye Xi, Peng Su, Bo Meng, Xiaoyun Shao, Beisha Tang, Qian Yang, Zixu Ma. p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease. Aging cell. vol 20. issue 10. 2021-11-09. PMID:34528746. |
interestingly, drosha level was specifically reduced in neurons of the cortex and hippocampus but not in the cerebellum in the ad brain samples. |
2021-11-09 |
2023-08-13 |
human |
| Mizael Machado, Tais M Wilson, Davi E R Sousa, Alexandra A B Gonçalves, Christine S Martins, Marcio B Castr. Uraemic Encephalopathy in a Persian Cat with Chronic Kidney Disease. Journal of comparative pathology. vol 180. 2021-11-08. PMID:33222866. |
there was symmetrical, bilateral spongy vacuolation of the white matter of the basal nuclei and cerebellum and alzheimer type ii astrocytes in the cerebral cortex and hippocampus. |
2021-11-08 |
2023-08-13 |
cat |