| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Artem P Gureev, Nadezda V Andrianova, Irina B Pevzner, Ljubava D Zorova, Ekaterina V Chernyshova, Irina S Sadovnikova, Dmitry V Chistyakov, Vasily A Popkov, Dmitry S Semenovich, Valentina A Babenko, Denis N Silachev, Dmitry B Zorov, Egor Y Plotnikov, Vasily N Popo. Dietary restriction modulates mitochondrial DNA damage and oxylipins profile in aged rats. The FEBS journal. 2022-04-04. PMID:35373508. |
dr promoted an increase in the amount of mtdna in the cerebellum and hippocampus. |
2022-04-04 |
2023-08-13 |
rat |
| Myriam Moreno, Crystal Minjarez, Jose Vigil, James E Orfila, Roxanna Schmidt, Amelia Burch, Danelle J Carter, Molly Kubesh, Joan Yonchek, Robert M Dietz, Nidia Quillina. Differences in hippocampal plasticity and memory outcomes in anterior versus posterior cerebellar stroke. Neurobiology of disease. 2022-03-26. PMID:35337949. |
differences in hippocampal plasticity and memory outcomes in anterior versus posterior cerebellar stroke. |
2022-03-26 |
2023-08-13 |
mouse |
| Myriam Moreno, Crystal Minjarez, Jose Vigil, James E Orfila, Roxanna Schmidt, Amelia Burch, Danelle J Carter, Molly Kubesh, Joan Yonchek, Robert M Dietz, Nidia Quillina. Differences in hippocampal plasticity and memory outcomes in anterior versus posterior cerebellar stroke. Neurobiology of disease. 2022-03-26. PMID:35337949. |
the hippocampus plays a key role in memory acquisition, a cognitive domain that is negatively impacted by posterior cerebellar stroke, and there is increasing evidence that the cerebellum can affect hippocampal function in health and disease. |
2022-03-26 |
2023-08-13 |
mouse |
| Seung Yeon Seo, Soo-Jong Kim, Jungsu S Oh, Jinwha Chung, Seog-Young Kim, Seung Jun Oh, Segyeong Joo, Jae Seung Ki. Unified Deep Learning-Based Mouse Brain MR Segmentation: Template-Based Individual Brain Positron Emission Tomography Volumes-of-Interest Generation Without Spatial Normalization in Mouse Alzheimer Model. Frontiers in aging neuroscience. vol 14. 2022-03-21. PMID:35309883. |
we generated both skull-stripping masks and individual brain-specific volumes-of-interest (vois-cortex, hippocampus, striatum, thalamus, and cerebellum) based on inverse spatial normalization (isn) and deep convolutional neural network (deep cnn) models. |
2022-03-21 |
2023-08-13 |
mouse |
| Yasmin A Ebedy, Eman I Hassanen, Ahmed M Hussien, Marwa A Ibrahim, M O Elshazl. Neurobehavioral Toxicity Induced by Carbendazim in Rats and the Role of iNOS, Cox-2, and NF-κB Signalling Pathway. Neurochemical research. 2022-03-21. PMID:35312909. |
there were extensive neuropathological alterations in the cerebrum, hippocampus, and cerebellum with strong caspase-3, inos, cox-2 protein expressions mainly in rats receiving 600 mg/kg cbz at each time point. |
2022-03-21 |
2023-08-13 |
human |
| Anastasia Rumyantseva, Milica Popovic, Aleksandra Trifunovi. CLPP deficiency ameliorates neurodegeneration caused by impaired mitochondrial protein synthesis. Brain : a journal of neurology. 2022-03-03. PMID:35240691. |
here, we build upon this finding by showing that clpp depletion is indeed beneficial in vivo for various types of neuronal populations, including purkinje cells in the cerebellum and cortical and hippocampal neurons in the forebrain, as it strongly improves distinct phenotypes of mitochondria encephalopathy, driven by the deficiency of the mitochondrial aspartyl trna synthase dars2. |
2022-03-03 |
2023-08-13 |
mouse |
| Karli K Watson, Angela D Bryan, Rachel E Thayer, Jarrod M Ellingson, Carillon J Skrzynski, Kent E Hutchiso. Cannabis Use and Resting State Functional Connectivity in the Aging Brain. Frontiers in aging neuroscience. vol 14. 2022-02-28. PMID:35221994. |
we found stronger connectivity between sources in the hippocampus and parahippocampal cortex, and targets in the anterior lobes of the cerebellum in older adult cannabis users relative to non-users. |
2022-02-28 |
2023-08-13 |
Not clear |
| Laure Rondi-Rei. The cerebellum on the epilepsy frontline. Trends in neurosciences. 2022-02-27. PMID:35219523. |
this study provides insights into how the cerebellum impacts hippocampal activity and opens the way to possible applications for treating temporal lobe epilepsy. |
2022-02-27 |
2023-08-13 |
mouse |
| Yu Liu, Samuel S McAfee, Meike E Van Der Heijden, Mukesh Dhamala, Roy V Sillitoe, Detlef H Hec. Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making. Cerebellum (London, England). 2022-02-26. PMID:35218525. |
with recent evidence that purkinje cells in the cerebellar lobulus simplex (ls) represent information about the phase and phase differences of gamma oscillations in the mpfc and dorsal hippocampus, we hypothesized that ls might be involved in the modulation of mpfc-hippocampal gamma coherence. |
2022-02-26 |
2023-08-13 |
mouse |
| Naoki Yoshida, Yugo Kato, Hirokatsu Takatsu, Koji Fuku. Relationship between Cognitive Dysfunction and Age-Related Variability in Oxidative Markers in Isolated Mitochondria of Alzheimer's Disease Transgenic Mouse Brains. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203488. |
in a western blot analysis using isolated mitochondria from three brain regions (cerebral cortex, cerebellum, and hippocampus), nmnat-3 expression in the hippocampi of aged ad mice was significantly lower than that of young ad mice. |
2022-02-25 |
2023-08-13 |
mouse |
| J N Bissonnette, A M Francis, S MacNeil, C E Crocker, P G Tibbo, D J Fishe. Glutamate and N-Acetylaspartate Alterations Observed in Early Phase Psychosis: A Systematic Review of Proton Magnetic Resonance Spectroscopy Studies. Psychiatry research. Neuroimaging. vol 321. 2022-02-20. PMID:35183897. |
no studies reported glutamate alterations in the hippocampus or cerebellum. |
2022-02-20 |
2023-08-13 |
Not clear |
| Shima Ferdos, Johannes Brockhaus, Markus Missler, Astrid Rohlman. Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons. Frontiers in neuroanatomy. vol 15. 2022-02-17. PMID:35173587. |
in conclusion, based on the validation from the two deletion strategies in conditional and constitutive ko mice, two neuronal populations from the hippocampus and cerebellum, and two experimental protocols in cultured neurons and in the brain tissue, this study presented morphological evidence that the number of dcvs at synapses is altered in the absence of β-nrxns. |
2022-02-17 |
2023-08-13 |
mouse |
| Anca R Rǎdulescu, Gabrielle C Todd, Cassandra L Williams, Benjamin A Bennink, Alex A Lemus, Haley E Chesbro, Justin R Bourgeois, Ashley M Kopec, Damian G Zuloaga, Annalisa Scimem. Estimating the glutamate transporter surface density in distinct sub-cellular compartments of mouse hippocampal astrocytes. PLoS computational biology. vol 18. issue 2. 2022-02-04. PMID:35120128. |
glutamate transporters are abundantly expressed in astrocytes, and previous estimates have been obtained about their surface expression in astrocytes of the rat hippocampus and cerebellum. |
2022-02-04 |
2023-08-13 |
mouse |
| A Torres-Herraez, T C Watson, L Rondi-Rei. Delta oscillations coordinate intra-cerebellar and cerebello-hippocampal network dynamics during sleep. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-29. PMID:35091502. |
during non-rem sleep, prominent delta frequency coherence was observed between lobule vi and hippocampus while non-rem associated hippocampal sharp wave ripple (swr) activity evoked discrete lfp modulation in all recorded cerebellar regions, with the shortest latency effects in lobule vi. |
2022-01-29 |
2023-08-13 |
mouse |
| A Torres-Herraez, T C Watson, L Rondi-Rei. Delta oscillations coordinate intra-cerebellar and cerebello-hippocampal network dynamics during sleep. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-29. PMID:35091502. |
during rem, cerebellar delta phase significantly modulated hippocampal theta frequency, and this effect was greatest when psps were abundant. |
2022-01-29 |
2023-08-13 |
mouse |
| A Torres-Herraez, T C Watson, L Rondi-Rei. Delta oscillations coordinate intra-cerebellar and cerebello-hippocampal network dynamics during sleep. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-29. PMID:35091502. |
psps were phase locked to cerebellar delta oscillation peak and hippocampal theta oscillation trough, respectively. |
2022-01-29 |
2023-08-13 |
mouse |
| Zhenyao Ye, Chen Mo, Hongjie Ke, Qi Yan, Chixiang Chen, Peter Kochunov, L Elliot Hong, Braxton D Mitchell, Shuo Chen, Tianzhou M. Meta-Analysis of Transcriptome-Wide Association Studies across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction. Genes. vol 13. issue 1. 2022-01-21. PMID:35052378. |
we identified three major clusters of genes with different meta-patterns across tissues consistent in both cohorts, including homogenous genes associated with cpd in all brain tissues; partially homogeneous genes associated with cpd in cortex, cerebellum, and hippocampus tissues; and, lastly, the tissue-specific genes associated with cpd in only a few specific brain tissues. |
2022-01-21 |
2023-08-13 |
human |
| Shama Bhatia, Eliyas Arslan, Luis Rodriguez-Hernandez, Robert Bonin, Peter G Well. DNA damage and repair and epigenetic modification in the role of oxoguanine glycosylase 1 (OGG1) in brain development. Toxicological sciences : an official journal of the Society of Toxicology. 2022-01-17. PMID:35038743. |
herein, we show that ogg1 knockout mice at 2-3 months of age exhibit enhanced gene- and sex-dependent dna damage (strand breaks) and decreased epigenetic dna methylation marks (5-methylcytosine, 5-hydroxymethylcytosine), both of which were associated with increased cerebellar calbindin levels, reduced hippocampal postsynaptic function, altered body weight with age and disorders of brain function reflected in behavioural tests for goal-directed repetitive behaviour, anxiety and fear, object recognition and spatial memory, motor coordination and startle response. |
2022-01-17 |
2023-08-13 |
mouse |
| Filip Tichane. Psychiatric-Like Impairments in Mouse Models of Spinocerebellar Ataxias. Cerebellum (London, England). 2022-01-09. PMID:35000108. |
in sca1 mice with complex neuropathology, some of the psychiatric-like impairments are present even before marked cerebellar degeneration and ataxia and correlate with hippocampal atrophy. |
2022-01-09 |
2023-08-13 |
mouse |
| Li-Yun Zhu, Xiao-Li Liu, Qin Zheng, Yong-Jie Kang, Wen-Jing Li, Shuai Xiao, Yan-Fen Xiong, Ke-Zhen Cai, Meng-Qi Wu, Ming Yan. [Prediction of Q-markers of Citri Reticulatae Pericarpium volatile oil and GC-MS based quantitative analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 24. 2022-01-07. PMID:34994132. |
the core targets were mainly distributed in olfactory region, cerebral cortex, cerebellum, basal ganglia, hippocampus, and amygdala to exert the pharmacological effects. |
2022-01-07 |
2023-08-13 |
Not clear |