| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mengmeng Xu, Longxiang Xie, Zhaoxiao Yu, Jianping Xi. Roles of Protein N-Myristoylation and Translational Medicine Applications. Critical reviews in eukaryotic gene expression. vol 25. issue 3. 2016-08-23. PMID:26558949. |
protein n-myristoylation is a ubiquitous cotranslational and posttranslational modification catalyzed by myristoyl coa:protein n-myristoyltransferase (nmt), which attaches myristate, a rare 14-carbon saturated fatty acid, to an n-terminal glycine of some eukaryotic and virus proteins. |
2016-08-23 |
2023-08-13 |
Not clear |
| A Khadem, M Lourenço, E Delezie, L Maertens, A Goderis, R Mombaerts, M Höfte, V Eeckhaut, F Van Immerseel, G P J Janssen. Does release of encapsulated nutrients have an important role in the efficacy of xylanase in broilers? Poultry science. vol 95. issue 5. 2016-06-30. PMID:26908893. |
in addition, xylanase inclusion significantly increased the postprandial plasma glycine and triglycerides concentration, and led to elevated bacterial gene copies of butyryl coa:acetate coa-transferase, suggesting a prebiotic effect of xylanase addition through more than just the cage effect reduction. |
2016-06-30 |
2023-08-13 |
Not clear |
| Eva Nývltová, Courtney W Stairs, Ivan Hrdý, Jakub Rídl, Jan Mach, Jan Pačes, Andrew J Roger, Jan Tachez. Lateral gene transfer and gene duplication played a key role in the evolution of Mastigamoeba balamuthi hydrogenosomes. Molecular biology and evolution. vol 32. issue 4. 2016-05-13. PMID:25573905. |
additionally, we characterized 1) several canonical mitochondrial components including respiratory complex ii and the glycine cleavage system, 2) enzymes associated with anaerobic energy metabolism, including an unusual d-lactate dehydrogenase and acetyl coa synthase, and 3) a sulfate activation pathway. |
2016-05-13 |
2023-08-13 |
Not clear |
| Bosko M Stojanovski, Gloria C Ferreir. Asn-150 of Murine Erythroid 5-Aminolevulinate Synthase Modulates the Catalytic Balance between the Rates of the Reversible Reaction. The Journal of biological chemistry. vol 290. issue 52. 2016-05-10. PMID:26511319. |
5-aminolevulinate synthase (alas) catalyzes the first step in mammalian heme biosynthesis, the pyridoxal 5'-phosphate (plp)-dependent and reversible reaction between glycine and succinyl-coa to generate coa, co2, and 5-aminolevulinate (ala). |
2016-05-10 |
2023-08-13 |
Not clear |
| Bosko M Stojanovski, Gloria C Ferreir. Murine erythroid 5-aminolevulinate synthase: Adenosyl-binding site Lys221 modulates substrate binding and catalysis. FEBS open bio. vol 5. 2015-11-25. PMID:26605136. |
5-aminolevulinate synthase (alas) catalyzes the initial step of mammalian heme biosynthesis, the condensation between glycine and succinyl-coa to produce coa, co2, and 5-aminolevulinate. |
2015-11-25 |
2023-08-13 |
human |
| Huu Tam Nguyen, Hyunwoo Park, Karen L Koster, Rebecca E Cahoon, Hanh T M Nguyen, John Shanklin, Thomas E Clemente, Edgar B Cahoo. Redirection of metabolic flux for high levels of omega-7 monounsaturated fatty acid accumulation in camelina seeds. Plant biotechnology journal. vol 13. issue 1. 2015-09-01. PMID:25065607. |
we demonstrate a strategy for enhanced production of omega-7 monounsaturated fatty acids in camelina (camelina sativa) and soybean (glycine max) that is dependent on redirection of metabolic flux from the typical ∆9 desaturation of stearoyl (18:0)-acyl carrier protein (acp) to ∆9 desaturation of palmitoyl (16:0)-acyl carrier protein (acp) and coenzyme a (coa). |
2015-09-01 |
2023-08-13 |
Not clear |
| Can Zhao, Shutao M. Recent advances in the discovery of N-myristoyltransferase inhibitors. ChemMedChem. vol 9. issue 11. 2015-06-23. PMID:25125080. |
the attachment of a 14-carbon saturated fatty acid, myristate, from myristoyl-coa (14:0 coa) to the n-terminal glycine residue in a specific set of cellular proteins is commonly called protein n-myristoylation. |
2015-06-23 |
2023-08-13 |
Not clear |
| Mary Philip, Scott A Funkhouser, Edison Y Chiu, Susan R Phelps, Jeffrey J Delrow, James Cox, Pamela J Fink, Janis L Abkowit. Heme exporter FLVCR is required for T cell development and peripheral survival. Journal of immunology (Baltimore, Md. : 1950). vol 194. issue 4. 2015-04-22. PMID:25582857. |
all aerobic cells and organisms must synthesize heme from the amino acid glycine and the tricarboxylic acid cycle intermediate succinyl coa for incorporation into hemoproteins, such as the cytochromes needed for oxidative phosphorylation. |
2015-04-22 |
2023-08-13 |
Not clear |
| Elena Volodina, Marc Schürmann, Nicole Lindenkamp, Alexander Steinbüche. Characterization of propionate CoA-transferase from Ralstonia eutropha H16. Applied microbiology and biotechnology. vol 98. issue 8. 2014-11-21. PMID:24057402. |
in contrast, no products were detected with acetyl-coa and formiate, bromopropionate, glycine, pyruvate, 2-hydroxybutyrate, malonate, fumarate, itaconate, β-alanine, γ-aminobutyrate, levulate, glutarate or adipate as potential coa acceptor. |
2014-11-21 |
2023-08-12 |
Not clear |
| Howard Horng, Leslie Z Bene. The nonenzymatic reactivity of the acyl-linked metabolites of mefenamic acid toward amino and thiol functional group bionucleophiles. Drug metabolism and disposition: the biological fate of chemicals. vol 41. issue 11. 2014-05-12. PMID:23975029. |
however, mfa-amp was more reactive toward both gly and tau, 17.5-fold more reactive toward the n-acyl-amidation of taurine than its corresponding coa thioester, while mfa-coa displayed little reactivity toward glycine. |
2014-05-12 |
2023-08-12 |
rat |
| A Hille, C Purwin, J Ebe. Induction of enzymes of phytoalexin synthesis in cultured soybean cells by an elicitor from Phytophthora megasperma f. sp. glycinea. Plant cell reports. vol 1. issue 3. 2013-11-26. PMID:24259025. |
glycinea, induced rapid but transient increases in enzyme activities of general phenylpropanoid metabolism (phenylalanine ammonia-lyase and 4-coumarate: coa ligase) and of the flavonoid pathway (chalcone synthase) in cell suspension cultures of soybean (glycine max). |
2013-11-26 |
2023-08-12 |
Not clear |
| Herbert L Bonkovsky, Jun-Tao Guo, Weihong Hou, Ting Li, Tarun Narang, Manish Thapa. Porphyrin and heme metabolism and the porphyrias. Comprehensive Physiology. vol 3. issue 1. 2013-11-19. PMID:23720291. |
the first and rate-controlling step is the formation of delta-aminolevulinic acid (ala) from glycine plus succinyl coa, catalyzed by ala synthase. |
2013-11-19 |
2023-08-12 |
Not clear |
| Michael Rothmann, MinJin Kang, Reymundo Villa, Ioanna Ntai, James J La Clair, Neil L Kelleher, Eli Chapman, Michael D Burkar. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. vol 135. issue 16. 2013-11-07. PMID:23550886. |
metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme a. pantetheine and its corresponding disulfide pantethine play a key role in metabolism as building blocks of coenzyme a (coa), an essential cofactor utilized in ~4% of primary metabolism and central to fatty acid, polyketide, and nonribosomal peptide synthases. |
2013-11-07 |
2023-08-12 |
Not clear |
| Anna-Lena Kaufholz, Gregory A Hunter, Gloria C Ferreira, Thomas Lendrihas, Vanessa Hering, Gunhild Layer, Martina Jahn, Dieter Jah. Aminolaevulinic acid synthase of Rhodobacter capsulatus: high-resolution kinetic investigation of the structural basis for substrate binding and catalysis. The Biochemical journal. vol 451. issue 2. 2013-05-29. PMID:23363548. |
the first enzyme of haem biosynthesis, alas (5-aminolaevulinic acid synthase), catalyses the pyridoxal 5'-phosphate-dependent condensation of glycine and succinyl-coa to 5-aminolaevulinic acid, co(2) and coa. |
2013-05-29 |
2023-08-12 |
Not clear |
| Francesca Rampoldi, Roger Sandhoff, Robert W Owen, Hermann-Josef Gröne, Stefan Porubsk. A new, robust, and nonradioactive approach for exploring N-myristoylation. Journal of lipid research. vol 53. issue 11. 2013-03-06. PMID:22829651. |
myristoyl-coa (coa):protein n-myristoyltransferase (nmt) catalyzes protein modification through covalent attachment of a c14 fatty acid (myristic acid) to the n-terminal glycine of proteins, thus promoting protein-protein and protein-membrane interactions. |
2013-03-06 |
2023-08-12 |
human |
| Ng Shyh-Chang, Jason W Locasale, Costas A Lyssiotis, Yuxiang Zheng, Ren Yi Teo, Sutheera Ratanasirintrawoot, Jin Zhang, Tamer Onder, Juli J Unternaehrer, Hao Zhu, John M Asara, George Q Daley, Lewis C Cantle. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science (New York, N.Y.). vol 339. issue 6116. 2013-01-24. PMID:23118012. |
isotope labeling of mescs revealed that threonine provides a substantial fraction of both the cellular glycine and the acetyl-coenzyme a (coa) needed for sam synthesis. |
2013-01-24 |
2023-08-12 |
mouse |
| Takaaki Kubota, Yoshikazu Izum. Detection and characterization of a thermophilic biotin biosynthetic enzyme, 7-keto-8-aminopelargonic acid synthase, from various thermophiles. Bioscience, biotechnology, and biochemistry. vol 76. issue 4. 2012-11-19. PMID:22484932. |
substrate specificity experiments revealed that sytbiof was also able to catalyze the reaction of 2-amino-3-ketobutyrate coa ligase, a member of the α-oxoamine synthase family, and that it used acetyl-coa and glycine as substrates, like the ttha1582 protein of thermus thermophilus. |
2012-11-19 |
2023-08-12 |
Not clear |
| Elizabeth M Novak, Bernd O Keller, Sheila M Inni. Metabolic development in the liver and the implications of the n-3 fatty acid supply. American journal of physiology. Gastrointestinal and liver physiology. vol 302. issue 2. 2012-02-16. PMID:22094600. |
feeding rats 1.5% compared with <0.1% energy 18:3n-3 during gestation led to higher 20:5n-3 and 22:6n-3 in 3-day-old offspring liver, higher serine hydroxymethyltransferase, carnitine palmitoyl transferase, and acyl coa oxidase and lower pyruvate kinase and stearoyl coa desaturase gene expression, with higher cholesterol, nadph and glutathione, and lower glycine (p < 0.05). |
2012-02-16 |
2023-08-12 |
rat |
| Shiv Shankhar Kaundu. An aspartate to glycine change in the carboxyl transferase domain of acetyl CoA carboxylase and non-target-site mechanism(s) confer resistance to ACCase inhibitor herbicides in a Lolium multiflorum population. Pest management science. vol 66. issue 11. 2011-02-22. PMID:20648527. |
an aspartate to glycine change in the carboxyl transferase domain of acetyl coa carboxylase and non-target-site mechanism(s) confer resistance to accase inhibitor herbicides in a lolium multiflorum population. |
2011-02-22 |
2023-08-12 |
Not clear |
| K Sugae, E Frees. Requirement for Acetate and Glycine (or Serine) for Sporulation Without Growth of Bacillus subtilis. Journal of bacteriology. vol 104. issue 3. 2010-06-29. PMID:16559079. |
amino acid analysis of nutrient sporulation medium showed that glycine (but not serine) is present at a concentration of 0.3 mm at the beginning of the developmental period, thus allowing, in combination with an acetyl-coenzyme a (coa) precursor, sporulation but not growth. |
2010-06-29 |
2023-08-12 |
Not clear |