| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Corey M Johnson, Bin Huang, Steven L Roderick, Paul F Coo. Kinetic mechanism of the serine acetyltransferase from Haemophilus influenzae. Archives of biochemistry and biophysics. vol 429. issue 2. 2004-09-23. PMID:15313214. |
glycine is competitive versus l-serine and uncompetitive versus acetyl coa, while smc is competitive against oas and uncompetitive against coash. |
2004-09-23 |
2023-08-12 |
Not clear |
| Dongning He, Stephen Barnes, Charles N Falan. Rat liver bile acid CoA:amino acid N-acyltransferase: expression, characterization, and peroxisomal localization. Journal of lipid research. vol 44. issue 12. 2004-07-01. PMID:12951368. |
bile acid coa:amino acid n-acyltransferase (bat) is responsible for the amidation of bile acids with the amino acids taurine and glycine. |
2004-07-01 |
2023-08-12 |
mouse |
| Anne K Bendt, Andreas Burkovski, Steffen Schaffer, Michael Bott, Mike Farwick, Thomas Herman. Towards a phosphoproteome map of Corynebacterium glutamicum. Proteomics. vol 3. issue 8. 2004-05-17. PMID:12923788. |
by peptide mass fingerprinting, 41 different proteins were identified, namely 5-enolpyruvylshikimate 3-phosphate synthase, aconitase, acyl-coa carboxylase, acyl-coa synthetase, atp (synthase alpha- and beta-chain), carbamoyl-phosphate synthase, citrate synthase, cysteine synthase, dnak, the elongation factors g, p, ts and tu, enolase, fructose bisphosphate aldolase, fumarase, gap dehydrogenase, glutamine synthetase i, glycine hydroxymethyltransferase, groel2, gtpase, heat-inducible transcriptional repressor dnaj2, inorganic pyrophosphatase, isocitrate dehydrogenase, ketol-acid reductoisomerase, lactate dehydrogenase, leucine-trna ligase, lipoamide dehydrogenase, methionine synthase, o-acetylhomoserine sulfhydrylase, pyruvate carboxylase, pyruvate kinase, pyruvate oxidase, ribosomal protein s1, rna polymerase (beta-subunit), succinyl-coa:coa transferase, transketolase and udp-n-acetylmuramoyl-l-alanine ligase, besides a hypothetical 35k protein and a hypothetical glucose kinase. |
2004-05-17 |
2023-08-12 |
Not clear |
| G C Ferreira, J S Zhan. Mechanism of 5-aminolevulinate synthase and the role of the protein environment in controlling the cofactor chemistry. Cellular and molecular biology (Noisy-le-Grand, France). vol 48. issue 8. 2003-09-26. PMID:12699240. |
this reaction entails the condensation of glycine with succinyl-coenzyme a to yield 5-aminolevulinate, carbon dioxide and coa. |
2003-09-26 |
2023-08-12 |
Not clear |
| Nobutoki Takamune, Hirotoshi Hamada, Hideki Sugawara, Shogo Misumi, Shozo Shoj. Development of an enzyme-linked immunosorbent assay for measurement of activity of myristoyl-coenzyme A:protein N-myristoyltransferase. Analytical biochemistry. vol 309. issue 1. 2003-05-01. PMID:12381372. |
myristoyl-coenzyme a (coa):protein n-myristoyltransferase (nmt) catalyzes the covalent attachment of myristate to the n-terminal glycine residue of various proteins. |
2003-05-01 |
2023-08-12 |
Not clear |
| Nafsika H Georgopapadako. Antifungals targeted to protein modification: focus on protein N-myristoyltransferase. Expert opinion on investigational drugs. vol 11. issue 8. 2003-02-13. PMID:12150705. |
protein n-myristoylation, the cotranslational transfer of the 14-carbon saturated fatty acid myristate from coa to the amino-terminal glycine of several fungal proteins such as the adp-ribosylation factor (arf), presents such an attractive new target. |
2003-02-13 |
2023-08-12 |
Not clear |
| Junshun Zhang, Gloria C Ferreir. Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism. The Journal of biological chemistry. vol 277. issue 47. 2003-01-07. PMID:12191993. |
5-aminolevulinate synthase is a dimeric protein having an ordered kinetic mechanism with glycine binding before succinyl-coa and with aminolevulinate release after coa and carbon dioxide. |
2003-01-07 |
2023-08-12 |
Not clear |
| C Canavese, D Gabrielli, C Guida, M D Cappellin. [Nephrologists and porphyrias]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia. vol 19. issue 4. 2002-12-16. PMID:12369042. |
following the "trigger" enzyme delta-aminolevulinic acid (ala) synthase, which is capable of condensing succynil coa and glycine, seven additional enzymes are involved in the process that eventually leads to haeme biosynthesis. |
2002-12-16 |
2023-08-12 |
human |
| Gloria C Ferreira, Anton V Cheltso. Circular permutation of 5-aminolevulinate synthase as a tool to evaluate folding, structure and function. Cellular and molecular biology (Noisy-le-Grand, France). vol 48. issue 1. 2002-12-02. PMID:11929042. |
5-aminolevulinate synthase, a pyridoxal 5'-phosphate-dependent enzyme, catalyzes the condensation of glycine with succinyl-coenzyme a to yield aminolevulinate, carbon dioxide and coa. |
2002-12-02 |
2023-08-12 |
Not clear |
| A Schmidt, J Sivaraman, Y Li, R Larocque, J A Barbosa, C Smith, A Matte, J D Schrag, M Cygle. Three-dimensional structure of 2-amino-3-ketobutyrate CoA ligase from Escherichia coli complexed with a PLP-substrate intermediate: inferred reaction mechanism. Biochemistry. vol 40. issue 17. 2001-07-12. PMID:11318637. |
it acts in concert with threonine dehydrogenase and converts 2-amino-3-ketobutyrate, the product of threonine dehydrogenation by the latter enzyme, with the participation of cofactor coa, to glycine and acetyl-coa. |
2001-07-12 |
2023-08-12 |
human |
| A Paleka. Effect of pantothenic acid on hippurate formation in sodium benzoate-treated HepG2 cells. Pediatric research. vol 48. issue 3. 2001-02-08. PMID:10960503. |
in mammalian liver mitochondria, sb is activated by an atp-dependent reaction to its coa ester, before conjugation with glycine. |
2001-02-08 |
2023-08-12 |
Not clear |
| S Kocabiyik, I Erdura. The effect of valine substitution for glycine in the dimer interface of citrate synthase from Thermoplasma acidophilum on stability and activity. Biochemical and biophysical research communications. vol 275. issue 2. 2000-10-03. PMID:10964687. |
recombinant wild-type and gly 196 mutant tpcs enzymes were largely identical in terms of substrate specificities (k(m) for oxaloacetate and acetyl coa). |
2000-10-03 |
2023-08-12 |
cat |
| S J Steinberg, S J Mihalik, D G Kim, D A Cuebas, P A Watkin. The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase. The Journal of biological chemistry. vol 275. issue 21. 2000-06-30. PMID:10749848. |
unconjugated bile acids must be activated to their coa thioesters before conjugation to taurine or glycine can occur. |
2000-06-30 |
2023-08-12 |
human |
| M M Benning, T Haller, J A Gerlt, H M Holde. New reactions in the crotonase superfamily: structure of methylmalonyl CoA decarboxylase from Escherichia coli. Biochemistry. vol 39. issue 16. 2000-06-01. PMID:10769118. |
the carboxylate group of the thioether analogue of methylmalonyl coa is hydrogen bonded to the peptidic nh group of gly 110 and the imidazole ring of his 66. |
2000-06-01 |
2023-08-12 |
Not clear |
| Z Gregus, E Halászi, C D Klaasse. Effect of chlorophenoxyacetic acid herbicides on glycine conjugation of benzoic acid. Xenobiotica; the fate of foreign compounds in biological systems. vol 29. issue 6. 1999-08-26. PMID:10426554. |
neither 2,4-d nor 2,4,5-t influenced the hepatic concentrations of atp, coenzyme a (coa) or glycine; therefore, it is unlikely that they inhibit glycine conjugation of benzoic acid by diminishing the availability of co-substrates. |
1999-08-26 |
2023-08-12 |
rat |
| S Reverdatto, V Beilinson, N C Nielse. A multisubunit acetyl coenzyme A carboxylase from soybean. Plant physiology. vol 119. issue 3. 1999-05-03. PMID:10069834. |
a multisubunit form of acetyl coenzyme a (coa) carboxylase (accase) from soybean (glycine max) was characterized. |
1999-05-03 |
2023-08-12 |
Not clear |
| G A Hunter, G C Ferreir. Lysine-313 of 5-aminolevulinate synthase acts as a general base during formation of the quinonoid reaction intermediates. Biochemistry. vol 38. issue 12. 1999-04-19. PMID:10090759. |
5-aminolevulinate synthase catalyzes the condensation of glycine and succinyl-coa to form coa, carbon dioxide, and 5-aminolevulinate. |
1999-04-19 |
2023-08-12 |
Not clear |
| Z Gregus, T Fekete, E Halászi, A Gyurasics, C D Klaasse. Effects of fibrates on the glycine conjugation of benzoic acid in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 26. issue 11. 1998-12-03. PMID:9806950. |
benzoyl-coa synthetase and benzoyl-coa/glycine n-acyltransferase, respectively), utilizing atp, coa, and glycine. |
1998-12-03 |
2023-08-12 |
rat |
| Z Gregus, T Fekete, E Halászi, A Gyurasics, C D Klaasse. Effects of fibrates on the glycine conjugation of benzoic acid in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 26. issue 11. 1998-12-03. PMID:9806950. |
large doses of benzoate deplete coa from the liver, suggesting that the supply of coa may limit the capacity for glycine conjugation. |
1998-12-03 |
2023-08-12 |
rat |
| Z Gregus, T Fekete, E Halászi, A Gyurasics, C D Klaasse. Effects of fibrates on the glycine conjugation of benzoic acid in rats. Drug metabolism and disposition: the biological fate of chemicals. vol 26. issue 11. 1998-12-03. PMID:9806950. |
because fibrates are known to increase hepatic coa synthesis, we examined whether treatment with fenofibrate or bezafibrate enhanced the capacity of rats to conjugate benzoic acid with glycine. |
1998-12-03 |
2023-08-12 |
rat |