| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S L Dunn, J M Wilkinson, A Crawford, C L Le Maitre, R A D Bunnin. Cannabinoid WIN-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes. Osteoarthritis and cartilage. vol 22. issue 1. 2014-09-08. PMID:24211233. |
cannabinoid win-55,212-2 mesylate inhibits interleukin-1β induced matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human chondrocytes. |
2014-09-08 |
2023-08-12 |
human |
| Zili Zhang, Yao Guo, She Zhang, Yan Zhang, Yuqing Wang, Wenxia Ni, Desong Kong, Wenjing Chen, Shizhong Zhen. Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro. European journal of pharmacology. vol 721. issue 1-3. 2014-07-15. PMID:24076327. |
curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro. |
2014-07-15 |
2023-08-12 |
rat |
| Erinn S Raborn, Melissa Jamerson, Francine Marciano-Cabral, Guy A Cabra. Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins. Life sciences. vol 104. issue 1-2. 2014-07-01. PMID:24742657. |
cannabinoid inhibits hiv-1 tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins. |
2014-07-01 |
2023-08-13 |
human |
| Erinn S Raborn, Melissa Jamerson, Francine Marciano-Cabral, Guy A Cabra. Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins. Life sciences. vol 104. issue 1-2. 2014-07-01. PMID:24742657. |
the aim of this study was to assess the effect of select cannabinoids on human immunodeficiency virus type 1 (hiv-1) transactivating (tat) protein-enhanced monocyte-like cell adhesion to proteins of the extracellular matrix (ecm). |
2014-07-01 |
2023-08-13 |
human |
| Nicola Mastroianni, Cristina Postigo, Miren Lopez de Alda, Damia Barcel. Illicit and abused drugs in sewage sludge: method optimization and occurrence. Journal of chromatography. A. vol 1322. 2014-06-26. PMID:24275487. |
to the authors' knowledge, nine out of the 20 selected analytes, namely, cocaethylene, ephedrine, heroin, alprazolam, lysergic acid diethylamide (lsd), its metabolite 2-oxo-3-hydroxy-lsd, and the cannabinoids Δ(9)-tetrahydrocannabinol (thc), cannabinol (cbn) and cannabidiol (cbd), are investigated for the first time in this matrix. |
2014-06-26 |
2023-08-12 |
Not clear |
| Tamara N Dunn, Alison H Keenan, Anthony P Thomas, John W Newman, Sean H Adam. A diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-AG) in diet-induced obese mice. Nutrition & metabolism. vol 11. 2014-06-25. PMID:24963334. |
a diet containing a nonfat dry milk matrix significantly alters systemic oxylipins and the endocannabinoid 2-arachidonoylglycerol (2-ag) in diet-induced obese mice. |
2014-06-25 |
2023-08-13 |
mouse |
| Sebastien Anizan, Garry Milman, Nathalie Desrosiers, Allan J Barnes, David A Gorelick, Marilyn A Huesti. Oral fluid cannabinoid concentrations following controlled smoked cannabis in chronic frequent and occasional smokers. Analytical and bioanalytical chemistry. vol 405. issue 26. 2014-06-12. PMID:23954944. |
oral fluid (of) is an alternative biological matrix for monitoring cannabis intake in drug testing, and drugged driving (duid) programs, but of cannabinoid test interpretation is challenging. |
2014-06-12 |
2023-08-12 |
Not clear |
| Susana Sadler Simões, Antonio Castañera Ajenjo, Mário João Dia. Qualitative and quantitative analysis of THC, 11-hydroxy-THC and 11-nor-9-carboxy-THC in whole blood by ultra-performance liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. vol 25. issue 18. 2013-10-28. PMID:23657954. |
the method was fully validated, including selectivity and capacity of identification, according to the identification criteria (two transitions per substance, signal-to-noise ratio, relative retention time and ion ratio) without the presence of interferences, limit of detection (0.2 µg/l for thc and 0.5 µg/l for 11-oh-thc and thc-cooh), limit of quantitation (0.5 µg/l for all cannabinoids), recovery (53-115%), carryover, matrix effect (34-43%), linearity (0.5-100 µg/l), intra-assay precision (cv < 10% for the relative peak area ratios and <0.1% for the relative retention time), inter-assay accuracy (mean relative error <10%) and precision (cv <11%). |
2013-10-28 |
2023-08-12 |
Not clear |
| Stefan Kneisel, Michael Speck, Bjoern Moosmann, Todd M Corneillie, Nathaniel G Butlin, Volker Auwärte. LC/ESI-MS/MS method for quantification of 28 synthetic cannabinoids in neat oral fluid and its application to preliminary studies on their detection windows. Analytical and bioanalytical chemistry. vol 405. issue 14. 2013-10-17. PMID:23535743. |
the method was applied to authentic samples collected during two preliminary studies in order to obtain insights into the general detectability and detection windows of synthetic cannabinoids in this matrix. |
2013-10-17 |
2023-08-12 |
Not clear |
| Manuel Sergi, Natalia Battista, Camilla Montesano, Roberta Curini, Mauro Maccarrone, Dario Compagnon. Determination of the two major endocannabinoids in human plasma by μ-SPE followed by HPLC-MS/MS. Analytical and bioanalytical chemistry. vol 405. issue 2-3. 2013-07-05. PMID:22847477. |
the whole procedure has been validated following the fda guidelines for bioanalytical methods validation: the satisfactory recovery values, the negligible matrix effect and the good values of accuracy and reproducibility make it a simple and high-throughput analytical tool for clinical and biochemical studies on endocannabinoid signaling in humans. |
2013-07-05 |
2023-08-12 |
human |
| Marie Fabritius, Christian Staub, Patrice Mangin, Christian Girou. Distribution of free and conjugated cannabinoids in human bile samples. Forensic science international. vol 223. issue 1-3. 2013-06-20. PMID:22980143. |
furthermore, we suggest that the bile is the matrix of choice for the screening of phase ii cannabinoid metabolites. |
2013-06-20 |
2023-08-12 |
human |
| Svantje Tauber, Katrin Paulsen, Susanne Wolf, Peggy Synwoldt, Andreas Pahl, Regine Schneider-Stock, Oliver Ullric. Regulation of MMP-9 by a WIN-binding site in the monocyte-macrophage system independent from cannabinoid receptors. PloS one. vol 7. issue 11. 2013-04-23. PMID:23139770. |
we demonstrated that the prototypical cannabinoid agonist r(+)win55,212-2 (win) reduced the secretion of matrix metalloproteinase-9 (mmp-9) in a murine model of cigarette-smoke induced lung inflammation. |
2013-04-23 |
2023-08-12 |
Not clear |
| Sara L Dunn, J Mark Wilkinson, Aileen Crawford, Christine L Le Maitre, Rowena A D Bunnin. Cannabinoids: novel therapies for arthritis? Future medicinal chemistry. vol 4. issue 6. 2012-08-14. PMID:22530636. |
they have also been shown to prevent il-1-induced matrix breakdown of collagen and proteoglycan, indicating that cannabinoids may mediate chondroprotective effects. |
2012-08-14 |
2023-08-12 |
Not clear |
| Robert Ramer, Katharina Bublitz, Nadine Freimuth, Jutta Merkord, Helga Rohde, Maria Haustein, Philipp Borchert, Ellen Schmuhl, Michael Linnebacher, Burkhard Hin. Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 4. 2012-05-31. PMID:22198381. |
cannabinoids inhibit cancer cell invasion via increasing tissue inhibitor of matrix metalloproteinases-1 (timp-1). |
2012-05-31 |
2023-08-12 |
mouse |
| David M Schwope, Erin L Karschner, David A Gorelick, Marilyn A Huesti. Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration. Clinical chemistry. vol 57. issue 10. 2011-12-07. PMID:21836075. |
furthermore, there are no studies directly examining whole-blood cannabinoid pharmacokinetics, although this matrix is often the only available specimen. |
2011-12-07 |
2023-08-12 |
Not clear |
| Garry Milman, Allan J Barnes, David M Schwope, Eugene W Schwilke, Robert S Goodwin, Deana L Kelly, David A Gorelick, Marilyn A Huesti. Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration. Analytical and bioanalytical chemistry. vol 401. issue 2. 2011-11-23. PMID:21637933. |
oral fluid (of) is an increasingly accepted matrix for drug testing programs, but questions remain about its usefulness for monitoring cannabinoids. |
2011-11-23 |
2023-08-12 |
Not clear |
| Garry Milman, Allan J Barnes, David M Schwope, Eugene W Schwilke, Robert S Goodwin, Deana L Kelly, David A Gorelick, Marilyn A Huesti. Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration. Analytical and bioanalytical chemistry. vol 401. issue 2. 2011-11-23. PMID:21637933. |
expectorated of specimens (n = 360) were obtained from 10 adult daily cannabis smokers before, during, and after 37 20-mg oral Δ(9)-tetrahydrocannabinol (thc) doses over 9 days to characterize cannabinoid disposition in this matrix. |
2011-11-23 |
2023-08-12 |
Not clear |
| Dayong Lee, Garry Milman, Allan J Barnes, Robert S Goodwin, Jussi Hirvonen, Marilyn A Huesti. Oral fluid cannabinoids in chronic, daily Cannabis smokers during sustained, monitored abstinence. Clinical chemistry. vol 57. issue 8. 2011-09-26. PMID:21677094. |
oral fluid (of) is an accepted alternative biological matrix for drug treatment, workplace, and duid (driving under the influence of drugs) investigations, but establishing the cannabinoid of detection window and concentration cutoff criteria are important. |
2011-09-26 |
2023-08-12 |
Not clear |
| Martina J Rosenberg, Christina R Wolff, Ahmed El-Emawy, Miranda C Staples, Nora I Perrone-Bizzozero, Daniel D Savag. Effects of moderate drinking during pregnancy on placental gene expression. Alcohol (Fayetteville, N.Y.). vol 44. issue 7-8. 2011-03-11. PMID:20053520. |
to date, quantitative real-time polymerase chain reaction analysis has confirmed significant alterations in gene expression for 22 genes, including genes encoding for three calcium binding proteins, two matrix metalloproteinases, the cannabinoid 1, galanin 2 and toll-like receptor 4, iodothyronine deiodinase 2, 11-β hydroxysteroid dehydrogenase 2, placental growth factor, transforming growth factor alpha, gremlin 1, and epithelial growth factor (egf)-containing extracellular matrix protein. |
2011-03-11 |
2023-08-12 |
rat |
| Robert Ramer, Burkhard Hin. Cyclooxygenase-2 and tissue inhibitor of matrix metalloproteinases-1 confer the antimigratory effect of cannabinoids on human trabecular meshwork cells. Biochemical pharmacology. vol 80. issue 6. 2010-08-12. PMID:20488167. |
this study therefore investigates the impact of two cannabinoids, delta(9)-tetrahydrocannabinol (thc) and r(+)-methanandamide (ma), on the migration of human tm cells and the involvement of the pg-synthesizing enzyme cyclooxygenase-2 (cox-2) and one of its potential downstream targets, the tissue inhibitor of matrix metalloproteinases-1 (timp-1), to this response. |
2010-08-12 |
2023-08-12 |
human |