| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert Ramer, Burkhard Hin. Cyclooxygenase-2 and tissue inhibitor of matrix metalloproteinases-1 confer the antimigratory effect of cannabinoids on human trabecular meshwork cells. Biochemical pharmacology. vol 80. issue 6. 2010-08-12. PMID:20488167. |
cyclooxygenase-2 and tissue inhibitor of matrix metalloproteinases-1 confer the antimigratory effect of cannabinoids on human trabecular meshwork cells. |
2010-08-12 |
2023-08-12 |
human |
| Alexander Korzh, Ora Keren, Mikhal Gafni, Hilla Bar-Josef, Yosef Sarn. Modulation of extracellular signal-regulated kinase (ERK) by opioid and cannabinoid receptors that are expressed in the same cell. Brain research. vol 1189. 2008-06-02. PMID:18068691. |
in n18tg2 neuroblastoma cells, the opioid agonist etorphine and the cannabinoid agonist cp-55940 induced the phosphorylation of erk by a similar mechanism that involved activation of delta-opioid receptors or cb1 cannabinoid receptors coupled to gi/go proteins, matrix metalloproteases, vascular endothelial growth factor (vegf) receptors and mapk/erk kinase (mek). |
2008-06-02 |
2023-08-12 |
Not clear |
| Cristina Blázquez, María Salazar, Arkaitz Carracedo, Mar Lorente, Ainara Egia, Luis González-Feria, Amador Haro, Guillermo Velasco, Manuel Guzmá. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Cancer research. vol 68. issue 6. 2008-04-09. PMID:18339876. |
cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. |
2008-04-09 |
2023-08-12 |
mouse |
| Cristina Blázquez, María Salazar, Arkaitz Carracedo, Mar Lorente, Ainara Egia, Luis González-Feria, Amador Haro, Guillermo Velasco, Manuel Guzmá. Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. Cancer research. vol 68. issue 6. 2008-04-09. PMID:18339876. |
here, we evaluated the effect of cannabinoids on matrix metalloproteinase (mmp) expression and its effect on tumor cell invasion. |
2008-04-09 |
2023-08-12 |
mouse |
| Robert Ramer, Burkhard Hin. Inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. Journal of the National Cancer Institute. vol 100. issue 1. 2008-01-10. PMID:18159069. |
inhibition of cancer cell invasion by cannabinoids via increased expression of tissue inhibitor of matrix metalloproteinases-1. |
2008-01-10 |
2023-08-12 |
Not clear |
| Somnath Mukhopadhyay, David A Tuli. Endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. Cardiovascular & hematological agents in medicinal chemistry. vol 5. issue 4. 2008-01-03. PMID:17979695. |
endocannabinoid regulation of matrix metalloproteinases: implications in ischemic stroke. |
2008-01-03 |
2023-08-12 |
Not clear |
| Andrea Telek, Tamás Bíró, Eniko Bodó, Balázs I Tóth, István Borbíró, George Kunos, Ralf Pau. Inhibition of human hair follicle growth by endo- and exocannabinoids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 13. 2007-12-03. PMID:17567570. |
namely, the endocannabinoid n-arachidonoylethanolamide (anandamide, aea) as well as the exocannabinnoid delta (9) -tetrahydrocannabinol dose-dependently inhibited hair shaft elongation and the proliferation of hair matrix keratinocytes, and induced intraepithelial apoptosis and premature hf regression (catagen). |
2007-12-03 |
2023-08-12 |
human |
| Sharmistha Ghosh, Anju Preet, Jerome E Groopman, Ramesh K Ganj. Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes. Molecular immunology. vol 43. issue 14. 2006-08-10. PMID:16503355. |
cannabinoids were also found to downregulate the pma-enhanced enzyme activity of matrix metalloproteinase-9, which is known to play an important role in transendothelial migration. |
2006-08-10 |
2023-08-12 |
Not clear |
| Estery C Mbvundula, Rowena A D Bunning, K D Rainsfor. Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. The Journal of pharmacy and pharmacology. vol 58. issue 3. 2006-07-07. PMID:16536902. |
arthritis and cannabinoids: hu-210 and win-55,212-2 prevent il-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. |
2006-07-07 |
2023-08-12 |
cattle |
| Estery C Mbvundula, Rowena A D Bunning, K D Rainsfor. Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alpha-induced matrix degradation in bovine articular chondrocytes in-vitro. The Journal of pharmacy and pharmacology. vol 58. issue 3. 2006-07-07. PMID:16536902. |
it is concluded that biologically stable synthetic cannabinoids protect cartilage matrix from degradation induced by cytokines and this effect is possibly cb-receptor mediated and involves effects on prostaglandin and nitric oxide metabolism. |
2006-07-07 |
2023-08-12 |
cattle |
| Michael A Repka, Mahmoud A ElSohly, Manish Munjal, Samir A Ros. Temperature stability and bioadhesive properties of delta9-tetrahydrocannabinol incorporated hydroxypropylcellulose polymer matrix systems. Drug development and industrial pharmacy. vol 32. issue 1. 2006-04-27. PMID:16455601. |
post-production high performance liquid chromotography (hplc) analysis revealed that the processed systems contained at least 94% of thc and the relative percent formation of cbn was 0.5% at 120 degrees c and 0.4% at 160 degrees c compared to 1.6% at 200 degrees c. these findings indicate that the cannabinoid may be a plausible candidate for incorporation into systems utilizing hot-melt extrusion techniques for the development of an effective mucoadhesive transmucosal matrix system for delivery of thc. |
2006-04-27 |
2023-08-12 |
Not clear |
| Susanne Rösch, Robert Ramer, Kay Brune, Burkhard Hin. R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. The Journal of pharmacology and experimental therapeutics. vol 316. issue 3. 2006-04-13. PMID:16330497. |
r(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. |
2006-04-13 |
2023-08-12 |
human |
| Cristina Blázquez, M Llanos Casanova, Anna Planas, Teresa Gómez Del Pulgar, Concepción Villanueva, María J Fernández-Aceñero, Julián Aragonés, John W Huffman, José L Jorcano, Manuel Guzmá. Inhibition of tumor angiogenesis by cannabinoids. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 3. 2003-04-01. PMID:12514108. |
in vitro and in vivo experiments show that at least two mechanisms may be involved in this cannabinoid action: the direct inhibition of vascular endothelial cell migration and survival as well as the decrease of the expression of proangiogenic factors (vascular endothelial growth factor and angiopoietin-2) and matrix metalloproteinase-2 in the tumors. |
2003-04-01 |
2023-08-12 |
mouse |
| I G Sil'ki. [Possible mechanism of cannabinoid-mediated modulation of signal transduction through the basal ganglia]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 88. issue 2. 2002-05-22. PMID:11938644. |
in addition, cannabinoids can attenuate locomotor activity due to a reducing of glutamate/gaba release from axon terminals of subthalamic nucleus/striatonigral cells of matrix and subsequent decrease/increase in the activity of neurons of globus pallidus/substantia nigra pars reticulata. |
2002-05-22 |
2023-08-12 |
Not clear |
| V W Hanson, M H Buonarati, R C Baselt, N A Wade, C Yep, A A Biasotti, V C Reeve, A S Wong, M W Orbanowsk. Comparison of 3H- and 125I-radioimmunoassay and gas chromatography/mass spectrometry for the determination of delta 9-tetrahydrocannabinol and cannabinoids in blood and serum. Journal of analytical toxicology. vol 7. issue 2. 1983-07-29. PMID:6304423. |
it was found that serum was a better matrix than blood for determination of cannabinoids. |
1983-07-29 |
2023-08-12 |
human |