| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Benjamin John Floyd Dean, Sarah J B Snelling, Stephanie Georgina Dakin, Muhammad Kassim Javaid, Andrew Jonathan Car. In vitro effects of glutamate and N-methyl-D-aspartate receptor (NMDAR) antagonism on human tendon derived cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 33. issue 10. 2015-11-25. PMID:26041147. |
we propose that these effects of glutamate on tendon derived cells including reduced cell viability and altered matrix gene expression contribute to the pathogenesis of tendinopathy. |
2015-11-25 |
2023-08-13 |
human |
| Julia Klueva, Eckart D Gundelfinger, R Renato Frischknecht, Martin Hein. Intracellular Ca²⁺ and not the extracellular matrix determines surface dynamics of AMPA-type glutamate receptors on aspiny neurons. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1654. 2015-11-05. PMID:25225098. |
intracellular ca²⁺ and not the extracellular matrix determines surface dynamics of ampa-type glutamate receptors on aspiny neurons. |
2015-11-05 |
2023-08-13 |
Not clear |
| Julia Klueva, Eckart D Gundelfinger, R Renato Frischknecht, Martin Hein. Intracellular Ca²⁺ and not the extracellular matrix determines surface dynamics of AMPA-type glutamate receptors on aspiny neurons. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1654. 2015-11-05. PMID:25225098. |
the perisynaptic extracellular matrix (ecm) contributes to the control of the lateral mobility of ampa-type glutamate receptors (ampars) at spine synapses of principal hippocampal neurons. |
2015-11-05 |
2023-08-13 |
Not clear |
| Anat Elmann, Alona Telerman, Sharon Mordechay, Hilla Erlank, Miriam Rindner, Yoel Kashman, Rivka Ofi. Downregulation of microglial activation by achillolide A. Planta medica. vol 81. issue 3. 2015-11-03. PMID:25654405. |
in primary cultures of lipopolysaccharide-activated microglial cells, achillolide a inhibited the lipopolysaccharide-induced levels of proinflammatory and toxic mediators including glutamate, nitric oxide, matrix metalloproteinase-9, cyclooxygenase-2, induced nitric oxide synthase, interleukin-1β, and tumor necrosis factor-α. |
2015-11-03 |
2023-08-13 |
Not clear |
| R F Kanzafarova, A V Kazantseva, E K Khusnutdinov. [Genetic and environmental aspects of mathematical disabilities]. Genetika. vol 51. issue 3. 2015-06-12. PMID:26027366. |
the results of the second approach demonstrates that the matrix metalloproteinase 7 gene (mmp7), the glutamate receptor ionotropic kainate 1 gene (grik1), and the dynein axonemal heavy chain 5 gene (dna h5) are responsible for developing mathematical disabilities. |
2015-06-12 |
2023-08-13 |
Not clear |
| Yonatan Ganor, Mia Levit. The neurotransmitter glutamate and human T cells: glutamate receptors and glutamate-induced direct and potent effects on normal human T cells, cancerous human leukemia and lymphoma T cells, and autoimmune human T cells. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 8. 2015-05-12. PMID:24584970. |
for example, glutamate at several concentrations induces or enhances significantly very important functions of human t-leukemia and t-lymphoma cells, among them adhesion to the extracellular matrix, migration, in vivo engraftment into solid organs, and the production and secretion of the cancer-associated matrix metalloproteinase mmp-9 and its inducer cd147. |
2015-05-12 |
2023-08-12 |
human |
| Peter R Huypens, Mei Huang, Jamie W Josep. Overcoming the spatial barriers of the stimulus secretion cascade in pancreatic β-cells. Islets. vol 4. issue 1. 2015-01-28. PMID:22143007. |
the exchange of metabolites between cytosol and mitochondrial matrix is mediated via a set of mitochondrial carriers, including the aspartate-glutamate carrier (aralar1), α- ketoglutarate carrier (ogc), atp/adp carrier (aac), glutamate carrier (gc1), dicarboxylate carrier (dic) and citrate/isocitrate carrier (cic). |
2015-01-28 |
2023-08-12 |
Not clear |
| Zsuzsanna Szepesi, Eric Hosy, Blazej Ruszczycki, Monika Bijata, Marta Pyskaty, Arthur Bikbaev, Martin Heine, Daniel Choquet, Leszek Kaczmarek, Jakub Wlodarczy. Synaptically released matrix metalloproteinase activity in control of structural plasticity and the cell surface distribution of GluA1-AMPA receptors. PloS one. vol 9. issue 5. 2015-01-20. PMID:24853857. |
we report that endogenous matrix metalloproteinase (mmp) activity promotes the structural and functional plasticity of local synapses by its effect on glutamate receptor mobility and content. |
2015-01-20 |
2023-08-13 |
Not clear |
| Anja Bienholz, Ahmad Al-Taweel, Nancy F Roeser, Andreas Kribben, Thorsten Feldkamp, Joel M Weinber. Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation. PloS one. vol 9. issue 4. 2015-01-13. PMID:24728405. |
improvements of energization in the presence of fatty acids by glutamate were shown to result predominantly from lowering matrix oxaloacetate rather than from amelioration of transmembrane cycling of fatty acids and uncoupling. |
2015-01-13 |
2023-08-13 |
mouse |
| Asako Gondo, Takanori Shinotsuka, Ayaka Morita, Yoichiro Abe, Masato Yasui, Mutsuo Nuriy. Sustained down-regulation of β-dystroglycan and associated dysfunctions of astrocytic endfeet in epileptic cerebral cortex. The Journal of biological chemistry. vol 289. issue 44. 2014-12-31. PMID:25228692. |
this change is completely abolished by the pharmacological blockade of nmda-type glutamate receptors as well as by matrix metalloproteinase inhibitors. |
2014-12-31 |
2023-08-13 |
mouse |
| Carl G Gahmberg, Lin Ning, Sonja Paeta. ICAM-5: a neuronal dendritic adhesion molecule involved in immune and neuronal functions. Advances in neurobiology. vol 8. 2014-10-23. PMID:25300135. |
icam-5 is cleaved by matrix metalloproteases upon activation of glutamate receptors or degraded through endocytosis resulting in increased spine maturation. |
2014-10-23 |
2023-08-13 |
Not clear |
| C A McPherson, B A Merrick, G J Harr. In vivo molecular markers for pro-inflammatory cytokine M1 stage and resident microglia in trimethyltin-induced hippocampal injury. Neurotoxicity research. vol 25. issue 1. 2014-08-28. PMID:24002884. |
these changes occurred in the absence of changes in matrix metalloproteinase 9 and 12, neural cell adhesion molecule, metabotropic glutamate receptor (grm)3, and ly6/neurotoxin 1 (lynx1), as well as, a decrease in neurotrophin 3, glutamate receptor subunit epsilon (grin)-2b, and neurotrophic tyrosine kinase receptor, type 3. |
2014-08-28 |
2023-08-12 |
mouse |
| Hyejin Lee, Eun-Jae Lee, Yoo Sung Song, Eunjoon Ki. Long-term depression-inducing stimuli promote cleavage of the synaptic adhesion molecule NGL-3 through NMDA receptors, matrix metalloproteinases and presenilin/γ-secretase. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298159. |
ngl-3 cleavage is induced by nmda treatment in cultured neurons and low-frequency stimulation in brain slices and requires the activities of nmda glutamate receptors, matrix metalloproteinases (mmps) and presenilin/γ-secretase. |
2014-08-11 |
2023-08-12 |
Not clear |
| Sang-Sun Yoon, Sangmee Ahn J. Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease. Biomolecules & therapeutics. vol 20. issue 3. 2014-06-24. PMID:24130920. |
multiple aβ-degrading enzymes (ade) implicated in the clearance process have been identified, which include neprilysin, insulin-degrading enzyme, matrix metalloproteinase-9, glutamate carboxypeptidase ii and others. |
2014-06-24 |
2023-08-12 |
Not clear |
| Cláudia Caldeira, Ana F Oliveira, Carolina Cunha, Ana R Vaz, Ana S Falcão, Adelaide Fernandes, Dora Brite. Microglia change from a reactive to an age-like phenotype with the time in culture. Frontiers in cellular neuroscience. vol 8. 2014-06-11. PMID:24917789. |
in contrast, 16 div (aged) microglia evidenced ramified morphology and increased matrix metalloproteinase (mmp)-2 activation, as well as reduced mmp-9, glutamate release and nuclear factor kappa-b activation, in parallel with decreased expression of toll-like receptor (tlr)-2 and tlr-4, capacity to migrate and phagocytose. |
2014-06-11 |
2023-08-13 |
mouse |
| R K Gupta, S Prasa. Early down regulation of the glial Kir4.1 and GLT-1 expression in pericontusional cortex of the old male mice subjected to traumatic brain injury. Biogerontology. vol 14. issue 5. 2014-05-16. PMID:24026668. |
astroglia play multiple roles in brain function by providing matrix to neurons, secreting neurotrophic factors, maintaining k(+) and glutamate homeostasis and thereby controlling synaptic plasticity which undergoes alterations during aging. |
2014-05-16 |
2023-08-12 |
mouse |
| Stéphane Marret, Catherine Vanhulle, Annie Laquerrier. Pathophysiology of cerebral palsy. Handbook of clinical neurology. vol 111. 2014-04-01. PMID:23622161. |
biochemical key factors originating in cell death or cell process loss, observed in hypoxic-ischemic as well as inflammatory conditions, are excessive production of proinflammatory cytokines, oxidative stress, maternal growth factor deprivation, extracellular matrix modifications, and excessive release of glutamate, triggering the excitotoxic cascade. |
2014-04-01 |
2023-08-12 |
Not clear |
| X Chen, P Boesiger, A Hennin. J-refocused 1H PRESS DEPT for localized 13C MR spectroscopy. NMR in biomedicine. vol 26. issue 9. 2014-03-25. PMID:23440698. |
the suppression of j modulation during press and the substantial recovery of signal enhancement by j-refocused press-localized dept were demonstrated theoretically by product operator formalism, numerically by the spin density matrix simulations for different scalar coupling conditions, and experimentally with a glutamate phantom at various tes, as well as a colza oil phantom. |
2014-03-25 |
2023-08-12 |
human |
| R Hampp, A R Wellbur. Changes in the permeability of the inner mitochondrial membrane associated with plastid development. Planta. vol 131. issue 1. 2014-01-16. PMID:24424690. |
oxalo-acetate, succinate and α-keto-glutarate permeate most readily inner membranes of mitochondria isolated from laminae given 2 h illumination whilst glutamate and glycine show later and more general penetration into the matrix spaces of mitochondria from greening tissue. |
2014-01-16 |
2023-08-12 |
Not clear |
| Kampanart Huanbutta, Kamonrak Cheewatanakornkool, Katsuhide Terada, Jurairat Nunthanid, Pornsak Sriamornsa. Impact of salt form and molecular weight of chitosan on swelling and drug release from chitosan matrix tablets. Carbohydrate polymers. vol 97. issue 1. 2014-01-14. PMID:23769512. |
the matrix tablets made of chitosan glycolate (cgy) showed the greatest swelling in both acid and neutral media, compared to chitosan aspartate, chitosan glutamate and chitosan lactate. |
2014-01-14 |
2023-08-12 |
Not clear |