| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah Thomas Broome, Alessandro Castorin. The Anxiolytic Drug Buspirone Prevents Rotenone-Induced Toxicity in a Mouse Model of Parkinson's Disease. International journal of molecular sciences. vol 23. issue 3. 2022-02-15. PMID:35163768. |
buspirone attenuated the induction of interleukin-1β and interleukin-6 expression by rotenone, and this was paralleled by the upregulation of arginase-1, brain-derived neurotrophic factor (bdnf), and activity-dependent neuroprotective protein (adnp) in the midbrain, striatum, prefrontal cortex, amygdala, and hippocampus. |
2022-02-15 |
2023-08-13 |
mouse |
| D Halperin, A Stavsky, R Kadir, M Drabkin, O Wormser, Y Yogev, V Dolgin, R Proskorovski-Ohayon, Y Perez, H Nudelman, O Stoler, B Rotblat, T Lifschytz, A Lotan, G Meiri, D Gitler, O S Bir. CDH2 mutation affecting N-cadherin function causes attention-deficit hyperactivity disorder in humans and mice. Nature communications. vol 12. issue 1. 2021-11-30. PMID:34702855. |
specific downstream molecular pathways were affected in both the ventral midbrain and prefrontal cortex, with reduced tyrosine hydroxylase expression and dopamine levels. |
2021-11-30 |
2023-08-13 |
mouse |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
expression of h19, bc1, miat1, and malat1 lncrnas was determined from the midbrain, striatum, hypothalamus, prefrontal cortex (pfc), and hippocampus by real-time pcr on day 8 of the repeated injections. |
2021-11-04 |
2023-08-13 |
rat |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
the bc1 expression significantly altered in the midbrain, hypothalamus, and hippocampus, but not in the striatum and pfc after repeated morphine treatment. |
2021-11-04 |
2023-08-13 |
rat |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
the miat1 and malat1 expression site-specifically altered in the midbrain, hypothalamus, and striatum; however, no significant changes were detected in their expression in the pfc and hippocampus after repeated morphine treatment. |
2021-11-04 |
2023-08-13 |
rat |
| Iulia Zoicas, Sabine E Huber, Liubov S Kalinichenko, Erich Gulbins, Christian P Müller, Johannes Kornhube. Ceramides affect alcohol consumption and depressive-like and anxiety-like behavior in a brain region- and ceramide species-specific way in male mice. Addiction biology. vol 25. issue 6. 2021-09-28. PMID:31828921. |
our results revealed that c16, but not c8 and c20, ceramide altered alcohol drinking and emotional behavior in a brain region-specific way without altering tissue noradrenaline, dopamine, and serotonin levels in the prefrontal cortex, ventral striatum, and dorsal mesencephalon. |
2021-09-28 |
2023-08-13 |
mouse |
| Kiyohito Iigaya, Tobias U Hauser, Zeb Kurth-Nelson, John P O'Doherty, Peter Dayan, Raymond J Dola. The value of what's to come: Neural mechanisms coupling prediction error and the utility of anticipation. Science advances. vol 6. issue 25. 2021-07-05. PMID:32596456. |
specifically, ventromedial prefrontal cortex tracks the value of anticipatory utility, dopaminergic midbrain correlates with information that enhances anticipation, while sustained hippocampal activity mediates a functional coupling between these regions. |
2021-07-05 |
2023-08-13 |
human |
| Rong Li, Chongyu Hu, Liangcheng Wang, Ding Liu, Dingyang Liu, Wei Liao, Bo Xiao, Huafu Chen, Li Fen. Disruption of functional connectivity among subcortical arousal system and cortical networks in temporal lobe epilepsy. Brain imaging and behavior. vol 14. issue 3. 2021-04-27. PMID:30617780. |
gca analysis revealed that the casual effects among these regions in patients were significantly sparser than those in controls (p < 0.05, uncorrected), including decreased excitatory and inhibitory effects among the midbrain, thalamus and pfc, and decreased inhibitory effect from the cerebellum to pfc. |
2021-04-27 |
2023-08-13 |
Not clear |
| Corinde E Wiers, Jizheng Zhao, Peter Manza, Kristina Murani, Veronica Ramirez, Amna Zehra, Clara Freeman, Kai Yuan, Gene-Jack Wang, Sükrü Barış Demiral, Anna Rose Childress, Dardo Tomasi, Nora D Volko. Conscious and unconscious brain responses to food and cocaine cues. Brain imaging and behavior. vol 15. issue 1. 2021-04-27. PMID:32125616. |
fmri showed occipital cortex activation for food>neutral, cocaine>neutral and cocaine>food; dorsolateral prefrontal cortex for cocaine>neutral and cocaine>food, and midbrain for cocaine>food (all p |
2021-04-27 |
2023-08-13 |
human |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Adrien T Stanley, Pellegrino Lippiello, David Sulzer, Maria Concetta Miniac. Roles for the Dorsal Striatum in Aversive Behavior. Frontiers in cellular neuroscience. vol 15. 2021-03-08. PMID:33664651. |
our understanding of how the brain encodes aversive behaviors has been primarily focused on roles for the amygdala, hippocampus (hipp), prefrontal cortex, ventral midbrain, and ventral striatum. |
2021-03-08 |
2023-08-13 |
Not clear |
| Ronghui Li, Xuxia Wang, Fuchun Lin, Tao Song, Xutao Zhu, Hao Le. Mapping accumulative whole-brain activities during environmental enrichment with manganese-enhanced magnetic resonance imaging. NeuroImage. vol 210. 2021-02-19. PMID:32004718. |
relative to the mice residing in a standard environment (se), the mice subjected to ee treatment had significantly enhanced regional memri signal intensities in the prefrontal cortex, somatosensory cortices, basal ganglia, amygdala, motor thalamus, lateral hypothalamus, ventral hippocampus and midbrain dopaminergic areas at the end of the 7-day exposure, likely attributing to enhanced mn |
2021-02-19 |
2023-08-13 |
mouse |
| Andreea Oliviana Diaconescu, Madeline Stecy, Lars Kasper, Christopher J Burke, Zoltan Nagy, Christoph Mathys, Philippe N Toble. Neural arbitration between social and individual learning systems. eLife. vol 9. 2021-02-11. PMID:32779568. |
arbitrating in favor of self-gathered information activated the dorsolateral prefrontal cortex and the midbrain, whereas arbitrating in favor of social information engaged the ventromedial prefrontal cortex and the amygdala. |
2021-02-11 |
2023-08-13 |
human |
| Michael Freedberg, Andrew C Toader, Eric M Wassermann, Joel L Vos. Competitive and cooperative interactions between medial temporal and striatal learning systems. Neuropsychologia. vol 136. 2020-12-11. PMID:31733236. |
the involvement of other regions, such as midbrain dopaminergic nuclei and the prefrontal cortex, may promote and mediate cooperation between the striatum and the mtl during learning. |
2020-12-11 |
2023-08-13 |
Not clear |
| Elizabeth Ruiz-Sánchez, José Pedraza-Chaverri, Omar N Medina-Campos, Perla D Maldonado, Patricia Roja. S-allyl Cysteine, a Garlic Compound, Produces an Antidepressant-Like Effect and Exhibits Antioxidant Properties in Mice. Brain sciences. vol 10. issue 9. 2020-10-27. PMID:32859119. |
oxidative stress markers (reactive oxygen species, superoxide production, lipid peroxidation, and antioxidant enzymes activities) were analyzed in the midbrain, prefrontal cortex, and hippocampus. |
2020-10-27 |
2023-08-13 |
mouse |
| Josette Alsebaaly, Emilie Dugast, Laure Favot, Lydia Rabbaa Khabbaz, Marcello Solinas, Nathalie Thirie. Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30618609. |
in this study, we investigated whether alcohol consumption in a two-bottle choice paradigm followed by 3 weeks of abstinence could alter the expression of genes encoding proteins involved in cholesterol homeostasis in brain regions involved in addiction and relapse, namely the prefrontal cortex (pfc), the nucleus accumbens (nac), the mesencephalon and the amygdala. |
2020-10-01 |
2023-08-13 |
rat |
| Josette Alsebaaly, Emilie Dugast, Laure Favot, Lydia Rabbaa Khabbaz, Marcello Solinas, Nathalie Thirie. Persistent Neuroadaptations in the Expression of Genes Involved in Cholesterol Homeostasis Induced by Chronic, Voluntary Alcohol Intake in Rats. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30618609. |
interestingly, these changes appeared to be region-specific and suggest that previous chronic exposure to alcohol might durably increase cholesterol metabolism in the pfc, the nac and the mesencephalon and decrease cholesterol metabolism in the amygdala. |
2020-10-01 |
2023-08-13 |
rat |
| Mary L Schneider, Colleen F Moore, Elizabeth O Ahlers, Todd E Barnhart, Bradley T Christian, Onofre T DeJesus, Jonathan W Engle, James E Holden, Julie A Larson, Jeffrey M Moirano, Dhanabalan Murali, Robert J Nickles, Leslie M Resch, Alexander K Convers. PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder. Frontiers in integrative neuroscience. vol 13. 2020-10-01. PMID:31379528. |
clinical research indicates that children with spd show greater prevalence of difficulties in complex cognitive behavior including working memory, behavioral flexibility, and regulation of sensory and affective functions, which are related to prefrontal cortex (pfc), striatal, and midbrain regions. |
2020-10-01 |
2023-08-13 |
human |
| Robert Hitzemann, Ovidiu D Iancu, Cheryl Reed, Harue Baba, Denesa R Lockwood, Tamara J Phillip. Regional Analysis of the Brain Transcriptome in Mice Bred for High and Low Methamphetamine Consumption. Brain sciences. vol 9. issue 7. 2020-09-30. PMID:31262025. |
three brain reward circuitry regions were explored, the nucleus accumbens (nac), prefrontal cortex (pfc), and ventral midbrain (vmb). |
2020-09-30 |
2023-08-13 |
mouse |
| Andrea Cari. Mesocorticolimbic Interactions Mediate fMRI-Guided Regulation of Self-Generated Affective States. Brain sciences. vol 10. issue 4. 2020-09-28. PMID:32276411. |
neuroimaging studies grounding on appraisal models of emotion emphasize a major role of prefrontal cortex in modulating emotion-related cortical and subcortical regions but usually neglect the contribution of the midbrain and other brainstem regions. |
2020-09-28 |
2023-08-13 |
Not clear |