| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Sang Jo, Sheri J Y Mizumor. Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 10. 2018-01-10. PMID:26400913. |
growing evidence indicates that midbrain dopamine (da) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. |
2018-01-10 |
2023-08-13 |
rat |
| Kanwar Virdee, Jiska Kentrop, Bianca Jupp, Bethany Venus, Daniel Hensman, Simon McArthur, James Wilkinson, Trevor W Robbins, Glenda Gillies, Jeffrey W Dalle. Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory. Psychopharmacology. vol 233. issue 21-22. 2017-11-16. PMID:27553822. |
however, the consequences of this expansion in midbrain dopamine (da) neurons for behavioural processes in adulthood are poorly understood, including working memory that depends on da transmission in the prefrontal cortex (pfc). |
2017-11-16 |
2023-08-13 |
rat |
| X Huang, Y-Y Chen, Y Shen, X Cao, A Li, Q Liu, Z Li, L-B Zhang, W Dai, T Tan, O Arias-Carrion, Y-X Xue, H Su, T-F Yua. Methamphetamine abuse impairs motor cortical plasticity and function. Molecular psychiatry. vol 22. issue 9. 2017-11-16. PMID:28831198. |
exposure to addictive drugs triggers synaptic plasticity in reward-related brain regions, such as the midbrain, nucleus accumbens and the prefrontal cortex. |
2017-11-16 |
2023-08-13 |
human |
| Tianqi Wang, Xiaolong Zhang, Ang Li, Meifang Zhu, Shu Liu, Wen Qin, Jin Li, Chunshui Yu, Tianzi Jiang, Bing Li. Polygenic risk for five psychiatric disorders and cross-disorder and disorder-specific neural connectivity in two independent populations. NeuroImage. Clinical. vol 14. 2017-11-03. PMID:28275544. |
consistent altered functional connectivity was found with the bilateral insula: for the left supplementary motor area and the left superior temporal gyrus with the cross-disorder pgrs, for the left insula and right middle and superior temporal lobe associated with the pgrs for autism, for the bilateral midbrain, posterior cingulate, cuneus, and precuneus associated with the pgrs for bd, and for the left angular gyrus and the left dorsolateral prefrontal cortex associated with the pgrs for schizophrenia. |
2017-11-03 |
2023-08-13 |
Not clear |
| Alexandru-Ştefan Niculae, Denis Pavă. From molecules to behavior: An integrative theory of autism spectrum disorder. Medical hypotheses. vol 97. 2017-07-27. PMID:27876135. |
in turn, this molecular syndrome generates an altered brain connectivity between the cerebellum, the midbrain dopaminergic areas, and the prefrontal cortex. |
2017-07-27 |
2023-08-13 |
Not clear |
| Marija Fjodorova, Eduardo M Torres, Stephen B Dunnet. Transplantation site influences the phenotypic differentiation of dopamine neurons in ventral mesencephalic grafts in Parkinsonian rats. Experimental neurology. vol 291. 2017-05-16. PMID:28131726. |
here we used rat foetal midbrain progenitors at two developmental stages corresponding to a peak in either a9 or a10 neurogenesis and examined their commitment to respective dopaminergic phenotypes by grafting cells into different forebrain regions that contain targets of either nigral a9 dopamine innervation (dorsal striatum), ventral tegmental area a10 dopamine innervation (nucleus accumbens and prefrontal cortex), or only sparse dopamine but rich noradrenaline innervation (hippocampus). |
2017-05-16 |
2023-08-13 |
rat |
| Chung-Man Moon, Gwang-Woo Jeon. Abnormalities in gray and white matter volumes associated with explicit memory dysfunction in patients with generalized anxiety disorder. Acta radiologica (Stockholm, Sweden : 1987). vol 58. issue 3. 2017-02-13. PMID:27273376. |
results patients with gad showed significantly reduced gm volumes in the midbrain (mb), thalamus, hippocampus (hip), insula, and superior temporal gyrus (stg); and reduced wm volumes in the mb, anterior limb of the internal capsule (alic), dorsolateral prefrontal cortex (dlpfc), and precentral gyrus (prg). |
2017-02-13 |
2023-08-13 |
human |
| A H Putman, A R Wolen, J L Harenza, R K Yordanova, B T Webb, E J Chesler, M F Mile. Identification of quantitative trait loci and candidate genes for an anxiolytic-like response to ethanol in BXD recombinant inbred strains. Genes, brain, and behavior. vol 15. issue 4. 2017-01-24. PMID:26948279. |
through integration of genome-wide mrna expression profiles of the mesocorticolimbic reward circuit (prefrontal cortex, nucleus accumbens and ventral midbrain) across the bxd ri panel, we identified high priority candidate genes within etanq1, the strongest of which was ninein (nin), a gsk3β-interacting protein that is highly expressed in the brain. |
2017-01-24 |
2023-08-13 |
mouse |
| Francesco Pistillo, Francesca Fasoli, Milena Moretti, Tristan McClure-Begley, Michele Zoli, Michael J Marks, Cecilia Gott. Chronic nicotine and withdrawal affect glutamatergic but not nicotinic receptor expression in the mesocorticolimbic pathway in a region-specific manner. Pharmacological research. vol 103. 2016-12-13. PMID:26631628. |
we analysed the effects of chronic nicotine treatment and withdrawal on the mesocorticolimbic pathway (a brain reward circuit in which addictive drugs induce widespread adaptations) by analysing the expression of nachrs in the midbrain, striatum and prefrontal cortex (pfc) of mice receiving intravenous infusions of nicotine (4mg/kg/h) or saline (control) for 14 days and mice sacrified two hours, and one, four and 14 days after treatment withdrawal. |
2016-12-13 |
2023-08-13 |
mouse |
| Chung-Man Moon, Gwang-Woo Jeon. Brain morphological alterations and cellular metabolic changes in patients with generalized anxiety disorder: A combined DARTEL-based VBM and (1)H-MRS study. Magnetic resonance imaging. vol 34. issue 4. 2016-12-13. PMID:26708039. |
the patients showed significantly reduced white matter (wm) volumes in the midbrain (mb), precentral gyrus (prg), dorsolateral prefrontal cortex (dlpfc) and anterior limb of the internal capsule (alic) compared to the controls. |
2016-12-13 |
2023-08-13 |
Not clear |
| Hyemin Han, Jingyuan Chen, Changwoo Jeong, Gary H Glove. Influence of the cortical midline structures on moral emotion and motivation in moral decision-making. Behavioural brain research. vol 302. 2016-12-13. PMID:26772629. |
we first demonstrate there are significant positive interactions between two central cms seed regions-i.e., the medial prefrontal cortex (mpfc) and posterior cingulate cortex (pcc)-and brain regions associated with moral functioning including the cerebellum, brainstem, midbrain, dorsolateral prefrontal cortex, orbitofrontal cortex and anterior insula (ai); on the other hand, the posterior insula (pi) showed significant negative interaction with the seed regions. |
2016-12-13 |
2023-08-13 |
human |
| Emilie Werlen, Matthew W Jone. Modulating the map: dopaminergic tuning of hippocampal spatial coding and interactions. Progress in brain research. vol 219. 2016-10-31. PMID:26072240. |
here, we review the current state of the circuitry and physiology underlying dopamine's actions, suggesting that--alongside local effects within hippocampus and prefrontal cortex--dopamine released from the midbrain ventral tegmental area is well positioned to dynamically tune interactions between limbic-cortical circuits through modulation of rhythmic network activity. |
2016-10-31 |
2023-08-13 |
Not clear |
| Brice Le François, Jeremy Soo, Anne M Millar, Mireille Daigle, Anne-Marie Le Guisquet, Samuel Leman, Frédéric Minier, Catherine Belzung, Paul R Alber. Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site. Neurobiology of disease. vol 82. 2016-08-24. PMID:26188176. |
in prefrontal cortex (pfc) and midbrain tissue, ucms increased 5-ht1a rna and protein levels, changes that are expected to decrease the brain serotonergic activity. |
2016-08-24 |
2023-08-13 |
mouse |
| Brice Le François, Jeremy Soo, Anne M Millar, Mireille Daigle, Anne-Marie Le Guisquet, Samuel Leman, Frédéric Minier, Catherine Belzung, Paul R Alber. Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site. Neurobiology of disease. vol 82. 2016-08-24. PMID:26188176. |
chronic imipramine treatment fully reversed the ucms-induced increase in methylation of the -681 cpg site in the pfc but not midbrain of stressed animals and also increased 5-ht1a expression in the pfc of control animals. |
2016-08-24 |
2023-08-13 |
mouse |
| Mia Apuschkin, Sara Stilling, Troels Rahbek-Clemmensen, Gunnar Sørensen, Guillaume Fortin, Freja Herborg Hansen, Jacob Eriksen, Louis-Eric Trudeau, Kristoffer Egerod, Ulrik Gether, Mattias Rickha. A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity. The European journal of neuroscience. vol 42. issue 7. 2016-07-20. PMID:26286107. |
midbrain dopaminergic (daergic) neurons are a heterogeneous cell group, composed of functionally distinct cell populations projecting to the basal ganglia, prefrontal cortex and limbic system. |
2016-07-20 |
2023-08-13 |
mouse |
| J L Rodríguez, I Ares, V Castellano, M Martínez, M R Martínez-Larrañaga, A Anadón, M A Martíne. Effects of exposure to pyrethroid cyfluthrin on serotonin and dopamine levels in brain regions of male rats. Environmental research. vol 146. 2016-06-27. PMID:26826775. |
after last dose of cyfluthrin, dopamine (da) and serotonin (5-ht) and its metabolites levels were determined in brain regions hypothalamus, midbrain, hippocampus, striatum and prefrontal cortex by hplc. |
2016-06-27 |
2023-08-13 |
rat |
| J L Rodríguez, I Ares, V Castellano, M Martínez, M R Martínez-Larrañaga, A Anadón, M A Martíne. Effects of exposure to pyrethroid cyfluthrin on serotonin and dopamine levels in brain regions of male rats. Environmental research. vol 146. 2016-06-27. PMID:26826775. |
moreover, cyfluthrin (20mg/kg bw, orally 6 days) evoked a statistically significant increase in 5-ht turnover in striatum and midbrain, and in da turnover in striatum and prefrontal cortex. |
2016-06-27 |
2023-08-13 |
rat |
| Yu-Chen Cha. Neural Correlates of Sex/Gender Differences in Humor Processing for Different Joke Types. Frontiers in psychology. vol 7. 2016-05-20. PMID:27199791. |
women also showed greater activation than men in the frontal-mesolimbic network associated with ejs, including the anterior (frontopolar) prefrontal cortex (apfc, ba 10) for executive control processes, and the amygdala and midbrain for reward anticipation and salience processes. |
2016-05-20 |
2023-08-13 |
Not clear |
| Sylvia Navailles, Karine Guillem, Caroline Vouillac-Mendoza, Serge H Ahme. Coordinated Recruitment of Cortical-Subcortical Circuits and Ascending Dopamine and Serotonin Neurons During Inhibitory Control of Cocaine Seeking in Rats. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 9. 2016-05-10. PMID:24872521. |
overall, we found that effective inhibitory control of cocaine seeking is associated with the coordinated recruitment of different top-down cortical-striatal circuits originating from different pfc territories, and of different bottom-up dopamine (da) and serotonin (5-ht) midbrain subsystems that normally modulate activity in these circuits. |
2016-05-10 |
2023-08-13 |
rat |
| Farooq H Maniyar, Till Sprenger, Teshamae Monteith, Christoph J Schankin, Peter J Goadsb. The premonitory phase of migraine--what can we learn from it? Headache. vol 55. issue 5. 2016-04-01. PMID:25919990. |
only one functional imaging study has been conducted in the premonitory phase that showed activation of posterolateral hypothalamus, midbrain tegmental area and substantia nigra, periaqueductal gray, dorsal pons, and various cortical areas including occipital, temporal, and prefrontal cortex. |
2016-04-01 |
2023-08-13 |
Not clear |