| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alok Nath Mohapatra, Shlomo Wagne. The role of the prefrontal cortex in social interactions of animal models and the implications for autism spectrum disorder. Frontiers in psychiatry. vol 14. 2023-07-06. PMID:37409155. |
the role of the prefrontal cortex in social interactions of animal models and the implications for autism spectrum disorder. |
2023-07-06 |
2023-08-14 |
Not clear |
| Hsing-Chang Ni, Yi-Lung Chen, Yi-Ping Chao, Chen-Te Wu, Rao-Shayn Chen, Tai-Li Chou, Susan Shur-Fen Gau, Hsiang-Yuan Li. A lack of efficacy of continuous theta burst stimulation over the left dorsolateral prefrontal cortex in autism: A double blind randomized sham-controlled trial. Autism research : official journal of the International Society for Autism Research. 2023-05-23. PMID:37219040. |
a lack of efficacy of continuous theta burst stimulation over the left dorsolateral prefrontal cortex in autism: a double blind randomized sham-controlled trial. |
2023-05-23 |
2023-08-14 |
Not clear |
| Hsing-Chang Ni, Yi-Lung Chen, Yi-Ping Chao, Chen-Te Wu, Rao-Shayn Chen, Tai-Li Chou, Susan Shur-Fen Gau, Hsiang-Yuan Li. A lack of efficacy of continuous theta burst stimulation over the left dorsolateral prefrontal cortex in autism: A double blind randomized sham-controlled trial. Autism research : official journal of the International Society for Autism Research. 2023-05-23. PMID:37219040. |
although previous open-label trials suggest the therapeutic potential of inhibitory repetitive transcranial magnetic stimulation (rtms) over the dorsolateral prefrontal cortex (dlpfc) in autism spectrum disorder (asd), methodological caveats exist. |
2023-05-23 |
2023-08-14 |
Not clear |
| Thanit Saeliw, Songphon Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya, Bumpenporn Sanannam, Chanachai Sae-Lee, Depicha Jindatip, Valerie W Hu, Tewarit Sarachan. Epigenetic Gene-Regulatory Loci in Alu Elements Associated with Autism Susceptibility in the Prefrontal Cortex of ASD. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108679. |
epigenetic gene-regulatory loci in alu elements associated with autism susceptibility in the prefrontal cortex of asd. |
2023-04-28 |
2023-08-14 |
Not clear |
| Tiffany Hong, Erin McBride, Brett D Dufour, Carmen Falcone, Mai Doan, Stephen G Noctor, Verónica Martínez-Cerdeñ. Synaptic boutons are smaller in chandelier cell cartridges in autism. PloS one. vol 18. issue 4. 2023-04-25. PMID:37097993. |
previous studies indicate that the number of ch cells is decreased in autism, and that gaba receptors are decreased in the ch cell synaptic target in the prefrontal cortex. |
2023-04-25 |
2023-08-14 |
human |
| Tiffany Hong, Erin McBride, Brett D Dufour, Carmen Falcone, Mai Doan, Stephen G Noctor, Verónica Martínez-Cerdeñ. Synaptic boutons are smaller in chandelier cell cartridges in autism. PloS one. vol 18. issue 4. 2023-04-25. PMID:37097993. |
to further identify ch cell alterations, we examined whether the length of cartridges, and the number, density, and size of ch cell synaptic boutons, differed in the prefrontal cortex of cases with autism versus control cases. |
2023-04-25 |
2023-08-14 |
human |
| Tiffany Hong, Erin McBride, Brett D Dufour, Carmen Falcone, Mai Doan, Stephen G Noctor, Verónica Martínez-Cerdeñ. Synaptic boutons are smaller in chandelier cell cartridges in autism. PloS one. vol 18. issue 4. 2023-04-25. PMID:37097993. |
we collected samples of postmortem human prefrontal cortex (brodmann area (ba) 9, 46, and 47) from 20 cases with autism and 20 age- and sex-matched control cases. |
2023-04-25 |
2023-08-14 |
human |
| Tiffany Hong, Erin McBride, Brett D Dufour, Carmen Falcone, Mai Doan, Stephen G Noctor, Verónica Martínez-Cerdeñ. Synaptic boutons are smaller in chandelier cell cartridges in autism. PloS one. vol 18. issue 4. 2023-04-25. PMID:37097993. |
the reduced size of ch cell boutons may result in reduced inhibitory signal transmission and impact the balance of excitation to inhibition in the prefrontal cortex in autism. |
2023-04-25 |
2023-08-14 |
human |
| Tanya Gandhi, Chin-Chi Liu, Tolulope T Adeyelu, Cade R Canepa, Charles C Le. Behavioral regulation by perineuronal nets in the prefrontal cortex of the CNTNAP2 mouse model of autism spectrum disorder. Frontiers in behavioral neuroscience. vol 17. 2023-03-31. PMID:36998537. |
behavioral regulation by perineuronal nets in the prefrontal cortex of the cntnap2 mouse model of autism spectrum disorder. |
2023-03-31 |
2023-08-14 |
mouse |
| Tanya Gandhi, Chin-Chi Liu, Tolulope T Adeyelu, Cade R Canepa, Charles C Le. Behavioral regulation by perineuronal nets in the prefrontal cortex of the CNTNAP2 mouse model of autism spectrum disorder. Frontiers in behavioral neuroscience. vol 17. 2023-03-31. PMID:36998537. |
these findings suggest that the neurobiological regulation of pnns and pvs in the pfc contribute to social interaction behaviors in neurological disorders including autism. |
2023-03-31 |
2023-08-14 |
mouse |
| Brett D Dufour, Erin McBride, Trevor Bartley, Pablo Juarez, Verónica Martínez-Cerdeñ. Distinct patterns of GABAergic interneuron pathology in autism are associated with intellectual impairment and stereotypic behaviors. Autism : the international journal of research and practice. 2023-03-20. PMID:36935610. |
we previously found that a specific type of inhibitory interneuron is reduced in number in the autism spectrum disorder prefrontal cortex. |
2023-03-20 |
2023-08-14 |
Not clear |
| Lijuan Luo, Tingyu Li, Qionghui Wu, Binlin Yuan, Chaoqun Hu, Ting Yang, Hua Wei, Jie Che. Retinoic acid administration normalizes aberrant microglial activation via regulating TREM2 transcription in the PFC of valproic acid induced autism rat. Neuroscience letters. 2023-03-16. PMID:36924930. |
retinoic acid administration normalizes aberrant microglial activation via regulating trem2 transcription in the pfc of valproic acid induced autism rat. |
2023-03-16 |
2023-08-14 |
rat |
| Federico Brandalise, Brian E Kalmbach, Erik P Cook, Darrin H Brage. Impaired dendritic spike generation in the Fragile X prefrontal cortex is due to loss of dendritic sodium channels. The Journal of physiology. 2023-01-10. PMID:36625320. |
dendritic spike threshold is depolarized in layer 5 pfc neurons in fx mice simultaneous somatic and dendritic recording with white noise current injections revealed that larger dendritic stimuli were required to elicit dendritic spikes in fx et neurons outside-out patch clamp recording revealed that dendritic sodium conductance density was lower in fx et neurons abstract: patients with fragile x syndrome, the leading monogenetic cause of autism, suffer from impairments related to the prefrontal cortex including working memory and attention. |
2023-01-10 |
2023-08-14 |
mouse |
| Carly M Drzewiecki, Amara S Brinks, Elli P Sellinger, Aditi D Doshi, Jessie Y Koh, Janice M Jurask. Brief postnatal exposure to bisphenol A affects apoptosis and gene expression in the medial prefrontal cortex and social behavior in rats with sex specificity. Neurotoxicology. 2022-11-28. PMID:36442689. |
because an increased number of neurons in the pfc is a characteristic of a subtype of autism spectrum disorder, we tested social preference following brief bpa exposure and also expression of a small group of genes. |
2022-11-28 |
2023-08-14 |
human |
| Bo Zhou, Xuehui Yan, Liu Yang, Xiaoli Zheng, Yunhua Chen, Yibu Liu, Yibing Ren, Jingang Peng, Yi Zhang, Jiayu Huang, Lei Tang, Min We. Effects of arginine vasopressin on the transcriptome of prefrontal cortex in autistic rat model. Journal of cellular and molecular medicine. 2022-10-14. PMID:36239083. |
to further explore the mechanisms of action of avp, we compared the pfc transcriptome changes before and after avp treatment in vpa-induced autism rat model. |
2022-10-14 |
2023-08-14 |
rat |
| Bo Zhou, Xuehui Yan, Liu Yang, Xiaoli Zheng, Yunhua Chen, Yibu Liu, Yibing Ren, Jingang Peng, Yi Zhang, Jiayu Huang, Lei Tang, Min We. Effects of arginine vasopressin on the transcriptome of prefrontal cortex in autistic rat model. Journal of cellular and molecular medicine. 2022-10-14. PMID:36239083. |
our results confirmed that avp could significantly improve synaptic and axon dysplasia and promote oligodendrocyte development in the prefrontal cortex in vpa-induced autism models by regulating multiple signalling pathways. |
2022-10-14 |
2023-08-14 |
rat |
| Abhishek Mishra, Rubal Singla, Rohit Kumar, AmitRaj Sharma, Rupa Joshi, Phulen Sarma, Gurjeet Kaur, Manisha Prajapat, Alka Bhatia, Bikash Medh. Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains. ACS chemical neuroscience. 2022-09-27. PMID:36166499. |
granulocyte colony-stimulating factor improved core symptoms of autism spectrum disorder via modulating glutamatergic receptors in the prefrontal cortex and hippocampus of rat brains. |
2022-09-27 |
2023-08-14 |
rat |
| Mehdi Zemestani, Omid Hoseinpanahi, Mohammad Ali Salehinejad, Michael A Nitsch. The impact of prefrontal transcranial direct current stimulation (tDCS) on theory of mind, emotion regulation and emotional-behavioral functions in children with autism disorder: A randomized, sham-controlled, and parallel-group study. Autism research : official journal of the International Society for Autism Research. 2022-09-07. PMID:36069668. |
this study examined the effects of transcranial direct current stimulation (tdcs) over the dorsolateral prefrontal cortex (dlpfc) on autism symptom severity, theory of mind, emotion regulation strategies, and emotional-behavioral functions in children with asd. |
2022-09-07 |
2023-08-14 |
Not clear |
| Megan Conrow-Graham, Jamal B Williams, Jennifer Martin, Ping Zhong, Qing Cao, Benjamin Rein, Zhen Ya. A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders. Brain : a journal of neurology. 2022-07-01. PMID:35775424. |
using post-mortem tissue from patients with autism spectrum disorder, we found diminished expression of adnp and pogz in the prefrontal cortex, a region highly implicated in neurodevelopmental disorders. |
2022-07-01 |
2023-08-14 |
mouse |
| Megan Conrow-Graham, Jamal B Williams, Jennifer Martin, Ping Zhong, Qing Cao, Benjamin Rein, Zhen Ya. A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders. Brain : a journal of neurology. 2022-07-01. PMID:35775424. |
these findings have uncovered the convergent functions of two top risk factors for autism spectrum disorder and intellectual disability in prefrontal cortex, providing a mechanism linking chromatin, transcriptional and synaptic dysregulation to cognitive deficits associated with neurodevelopmental disorders. |
2022-07-01 |
2023-08-14 |
mouse |