| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fumihito Saitow, Toru Takumi, Hidenori Suzuk. Change in serotonergic modulation contributes to the synaptic imbalance of neuronal circuit at the prefrontal cortex in the 15q11-13 duplication mouse model of autism. Neuropharmacology. vol 165. 2021-03-30. PMID:31901366. |
change in serotonergic modulation contributes to the synaptic imbalance of neuronal circuit at the prefrontal cortex in the 15q11-13 duplication mouse model of autism. |
2021-03-30 |
2023-08-13 |
mouse |
| Fumihito Saitow, Toru Takumi, Hidenori Suzuk. Change in serotonergic modulation contributes to the synaptic imbalance of neuronal circuit at the prefrontal cortex in the 15q11-13 duplication mouse model of autism. Neuropharmacology. vol 165. 2021-03-30. PMID:31901366. |
the prefrontal cortex (pfc) has been extensively studied in autism spectrum disorder (asd) in an attempt to understand the deficits in executive and other higher brain functions related to sociability and emotion. |
2021-03-30 |
2023-08-13 |
mouse |
| Rachel E Rodin, Yanmei Dou, Minseok Kwon, Maxwell A Sherman, Alissa M D'Gama, Ryan N Doan, Lariza M Rento, Kelly M Girskis, Craig L Bohrson, Sonia N Kim, Ajay Nadig, Lovelace J Luquette, Doga C Gulhan, Peter J Park, Christopher A Wals. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nature neuroscience. vol 24. issue 2. 2021-03-19. PMID:33432195. |
we characterize the landscape of somatic mutations-mutations occurring after fertilization-in the human brain using ultra-deep (~250×) whole-genome sequencing of prefrontal cortex from 59 donors with autism spectrum disorder (asd) and 15 control donors. |
2021-03-19 |
2023-08-13 |
human |
| Qianhui Yu, Zhisong He, Dmitry Zubkov, Shuyun Huang, Ilia Kurochkin, Xiaode Yang, Tobias Halene, Lothar Willmitzer, Patrick Giavalisco, Schahram Akbarian, Philipp Khaitovic. Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:30089790. |
here we investigated the lipidome composition of prefrontal cortex gray matter in 396 cognitively healthy individuals with ages spanning 100 years, as well as 67 adult individuals diagnosed with autism (asd), schizophrenia (sz), and down syndrome (ds). |
2021-03-15 |
2023-08-13 |
human |
| Karthikeyan Krishnamurthy, Michael K Yeung, Agnes S Chan, Yvonne M Y Ha. Effortful Control and Prefrontal Cortex Functioning in Children with Autism Spectrum Disorder: An fNIRS Study. Brain sciences. vol 10. issue 11. 2021-01-15. PMID:33233632. |
effortful control and prefrontal cortex functioning in children with autism spectrum disorder: an fnirs study. |
2021-01-15 |
2023-08-13 |
Not clear |
| Kate E Nichols, Nathan Fox, Peter Mund. Joint Attention, Self-Recognition, and Neurocognitive Function in Toddlers. Infancy : the official journal of the International Society on Infant Studies. vol 7. issue 1. 2021-01-12. PMID:33430537. |
data from a recent study of young children with autism suggests that performance on a delay nonmatch to sample (dnms) task associated with ventromedial prefrontal functions, but not an a-not-b/delayed response task associated with dorsolateral prefrontal cortex, was related to joint attention skills (dawson et al., 2002). |
2021-01-12 |
2023-08-13 |
Not clear |
| C H Lew, K M Groeniger, K L Hanson, D Cuevas, D M Z Greiner, B Hrvoj-Mihic, U Bellugi, C M Schumann, K Semendefer. Serotonergic innervation of the amygdala is increased in autism spectrum disorder and decreased in Williams syndrome. Molecular autism. vol 11. issue 1. 2020-12-31. PMID:32024554. |
williams syndrome (ws) and autism spectrum disorder (asd) are neurodevelopmental disorders that demonstrate overlapping genetic associations, dichotomous sociobehavioral phenotypes, and dichotomous pathological differences in neuronal distribution in key social brain areas, including the prefrontal cortex and the amygdala. |
2020-12-31 |
2023-08-13 |
Not clear |
| S Hossein Fatemi, Dean F Wong, James R Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D Folsom, Suma Jacob, George M Realmuto, José V Pardo, Susanne Le. Metabotropic glutamate receptor 5 tracer [ Cerebellum & ataxias. vol 5. 2020-10-01. PMID:29449954. |
postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mglur5) in cerebellar vermis and prefrontal cortex of individuals with autism. |
2020-10-01 |
2023-08-13 |
Not clear |
| Mitsuhiro Uratani, Toyosaku Ota, Junzo Iida, Kosuke Okazaki, Kazuhiko Yamamuro, Yoko Nakanishi, Naoko Kishimoto, Toshifumi Kishimot. Reduced prefrontal hemodynamic response in pediatric autism spectrum disorder measured with near-infrared spectroscopy. Child and adolescent psychiatry and mental health. vol 13. 2020-10-01. PMID:31297147. |
functional neuroimaging studies suggest that prefrontal cortex dysfunction is present in people with autism spectrum disorder (asd). |
2020-10-01 |
2023-08-13 |
Not clear |
| Hsing-Chang Ni, June Hung, Chen-Te Wu, Yu-Yu Wu, Chee-Jen Chang, Rou-Shayn Chen, Ying-Zu Huan. The Impact of Single Session Intermittent Theta-Burst Stimulation over the Dorsolateral Prefrontal Cortex and Posterior Superior Temporal Sulcus on Adults with Autism Spectrum Disorder. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28536500. |
the impact of single session intermittent theta-burst stimulation over the dorsolateral prefrontal cortex and posterior superior temporal sulcus on adults with autism spectrum disorder. |
2020-09-30 |
2023-08-13 |
human |
| Hsing-Chang Ni, June Hung, Chen-Te Wu, Yu-Yu Wu, Chee-Jen Chang, Rou-Shayn Chen, Ying-Zu Huan. The Impact of Single Session Intermittent Theta-Burst Stimulation over the Dorsolateral Prefrontal Cortex and Posterior Superior Temporal Sulcus on Adults with Autism Spectrum Disorder. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28536500. |
intermittent theta burst stimulation (itbs), a patterned repetitive transcranial magnetic stimulation, was applied over the posterior superior temporal sulcus (psts) or dorsolateral prefrontal cortex (dlpfc) to explore its impact in adults with autism spectrum disorder (asd). |
2020-09-30 |
2023-08-13 |
human |
| Stephen Grossberg, Devika Kishna. Neural Dynamics of Autistic Repetitive Behaviors and Fragile X Syndrome: Basal Ganglia Movement Gating and mGluR-Modulated Adaptively Timed Learning. Frontiers in psychology. vol 9. 2020-09-30. PMID:29593596. |
this article develops the istart neural model that proposes how specific imbalances in cognitive, emotional, timing, and motor processes that involve brain regions like prefrontal cortex, temporal cortex, amygdala, hypothalamus, hippocampus, and cerebellum may interact together to cause behavioral symptoms of autism. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zhaoqiang Qian, Ruoxin Zhang, Jinlong Zhou, Siqi Sun, Yuanyuan Di, Wei Ren, Yingfang Tia. RNA-Seq data on prefrontal cortex in valproic acid model of autism and control rats. Data in brief. vol 18. 2020-09-30. PMID:29900238. |
rna-seq data on prefrontal cortex in valproic acid model of autism and control rats. |
2020-09-30 |
2023-08-13 |
rat |
| Takahiro Ikeda, Masahiro Hirai, Takeshi Sakurada, Yukifumi Monden, Tatsuya Tokuda, Masako Nagashima, Hideo Shimoizumi, Ippeita Dan, Takanori Yamagat. Atypical neural modulation in the right prefrontal cortex during an inhibitory task with eye gaze in autism spectrum disorder as revealed by functional near-infrared spectroscopy. Neurophotonics. vol 5. issue 3. 2020-09-30. PMID:30211250. |
atypical neural modulation in the right prefrontal cortex during an inhibitory task with eye gaze in autism spectrum disorder as revealed by functional near-infrared spectroscopy. |
2020-09-30 |
2023-08-13 |
Not clear |
| Zdravko Petanjek, Dora Sedmak, Domagoj Džaja, Ana Hladnik, Mladen Roko Rašin, Nataša Jovanov-Milosevi. The Protracted Maturation of Associative Layer IIIC Pyramidal Neurons in the Human Prefrontal Cortex During Childhood: A Major Role in Cognitive Development and Selective Alteration in Autism. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:30923504. |
the protracted maturation of associative layer iiic pyramidal neurons in the human prefrontal cortex during childhood: a major role in cognitive development and selective alteration in autism. |
2020-09-30 |
2023-08-13 |
human |
| Jianling Chen, Wei Wu, Yingmei Fu, Shunying Yu, Donghong Cui, Min Zhao, Yasong Du, Jijun Li, Xiaohong L. Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602061. |
increased expression of fatty acid synthase and acetyl-coa carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism. |
2020-09-29 |
2023-08-13 |
rat |
| Jianling Chen, Wei Wu, Yingmei Fu, Shunying Yu, Donghong Cui, Min Zhao, Yasong Du, Jijun Li, Xiaohong L. Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602061. |
the primary aim of the present study was to investigate alterations in enzymes associated with fatty acid synthesis, namely fatty acid synthase (fasn) and acetyl-coa carboxylase (acc), in the prefrontal cortex and cerebellum of the valproic acid (vpa)-induced animal model of autism. |
2020-09-29 |
2023-08-13 |
rat |
| Jianling Chen, Wei Wu, Yingmei Fu, Shunying Yu, Donghong Cui, Min Zhao, Yasong Du, Jijun Li, Xiaohong L. Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602061. |
the results of western blotting and reverse transcription-quantitative polymerase chain reaction analyses demonstrated that the protein and mrna expression levels of fasn, acc and phospho-acc (pacc) were increased in the prefrontal cortex and cerebellum of the vpa model of autism. |
2020-09-29 |
2023-08-13 |
rat |
| Jianling Chen, Wei Wu, Yingmei Fu, Shunying Yu, Donghong Cui, Min Zhao, Yasong Du, Jijun Li, Xiaohong L. Increased expression of fatty acid synthase and acetyl-CoA carboxylase in the prefrontal cortex and cerebellum in the valproic acid model of autism. Experimental and therapeutic medicine. vol 12. issue 3. 2020-09-29. PMID:27602061. |
furthermore, in the prefrontal cortex and cerebellum of the vpa model of autism, ampk expression is increased, whereas pi3k and akt expression are unchanged. |
2020-09-29 |
2023-08-13 |
rat |
| Branka Hrvoj-Mihic, Kari L Hanson, Caroline H Lew, Lisa Stefanacci, Bob Jacobs, Ursula Bellugi, Katerina Semendefer. Basal Dendritic Morphology of Cortical Pyramidal Neurons in Williams Syndrome: Prefrontal Cortex and Beyond. Frontiers in neuroscience. vol 11. 2020-09-29. PMID:28848376. |
although this study utilized tissue held in formalin for a prolonged period of time and the number of neurons available for analysis was limited, our findings indicate that ws cortex, similar to that in other neurodevelopmental disorders such as down syndrome, rett syndrome, fragile x, and idiopathic autism, has altered morphology of basal dendrites on pyramidal neurons, which appears more prominent in selected areas of the pfc. |
2020-09-29 |
2023-08-13 |
human |