Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
John T Morgan, Gursharan Chana, Ian Abramson, Katerina Semendeferi, Eric Courchesne, Ian P Everal. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain research. vol 1456. 2012-08-23. PMID:22516109. |
abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. |
2012-08-23 |
2023-08-12 |
human |
John T Morgan, Gursharan Chana, Ian Abramson, Katerina Semendeferi, Eric Courchesne, Ian P Everal. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain research. vol 1456. 2012-08-23. PMID:22516109. |
to address this question, we examined microglial and neuronal organization in the dorsolateral prefrontal cortex, a region of pronounced early brain overgrowth in autism, via spatial pattern analysis of 13 male postmortem autism subjects and 9 controls. |
2012-08-23 |
2023-08-12 |
human |
John T Morgan, Gursharan Chana, Ian Abramson, Katerina Semendeferi, Eric Courchesne, Ian P Everal. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain research. vol 1456. 2012-08-23. PMID:22516109. |
our findings confirm that at least some microglial activation in the dorsolateral prefrontal cortex in autism is associated with a neuron-specific reaction, and suggest that neuronal organization may degrade later in life in the disorder. |
2012-08-23 |
2023-08-12 |
human |
Li Sui, Meng Che. Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories. Brain research bulletin. vol 87. issue 6. 2012-07-23. PMID:22326482. |
the prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher brain functions related to cognition, language, sociability and emotion. |
2012-07-23 |
2023-08-12 |
rat |
Naomi B Pitskel, Danielle Z Bolling, Caitlin M Hudac, Stephen D Lantz, Nancy J Minshew, Brent C Vander Wyk, Kevin A Pelphre. Brain mechanisms for processing direct and averted gaze in individuals with autism. Journal of autism and developmental disorders. vol 41. issue 12. 2012-07-19. PMID:21484518. |
significant group by condition interactions reflecting differential responses to direct versus averted gaze in people with autism relative to typically developing individuals were identified in the right temporoparietal junction, right anterior insula, left lateral occipital cortex, and left dorsolateral prefrontal cortex. |
2012-07-19 |
2023-08-12 |
human |
Gregory L Wallace, Philip Shaw, Nancy Raitano Lee, Liv S Clasen, Armin Raznahan, Rhoshel K Lenroot, Alex Martin, Jay N Gied. Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 14. 2012-05-29. PMID:22492041. |
using assessments of both subclinical autistic and subclinical antisocial traits within a large longitudinal sample of typically developing youth, we demonstrate dissociable neuroanatomic correlations that parallel those found in the frank clinical disorders of autism (e.g., superior temporal cortex) and antisociality (e.g., anterior prefrontal cortex). |
2012-05-29 |
2023-08-12 |
Not clear |
Kami Koldewyn, David Whitney, Susan M River. Neural correlates of coherent and biological motion perception in autism. Developmental science. vol 14. issue 5. 2012-02-17. PMID:21884323. |
activity in dorsolateral prefrontal cortex (dlpfc) and psts was predictive of biological motion thresholds in control participants but not in those with autism. |
2012-02-17 |
2023-08-12 |
human |
Eric Courchesne, Peter R Mouton, Michael E Calhoun, Katerina Semendeferi, Clelia Ahrens-Barbeau, Melodie J Hallet, Cynthia Carter Barnes, Karen Pierc. Neuron number and size in prefrontal cortex of children with autism. JAMA. vol 306. issue 18. 2011-11-15. PMID:22068992. |
neuron number and size in prefrontal cortex of children with autism. |
2011-11-15 |
2023-08-12 |
Not clear |
Eric Courchesne, Peter R Mouton, Michael E Calhoun, Katerina Semendeferi, Clelia Ahrens-Barbeau, Melodie J Hallet, Cynthia Carter Barnes, Karen Pierc. Neuron number and size in prefrontal cortex of children with autism. JAMA. vol 306. issue 18. 2011-11-15. PMID:22068992. |
autism often involves early brain overgrowth, including the prefrontal cortex (pfc). |
2011-11-15 |
2023-08-12 |
Not clear |
Tania Rinaldi, Catherine Perrodin, Henry Markra. Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism. Frontiers in neural circuits. vol 2. 2011-07-14. PMID:18989389. |
the prefrontal cortex has been extensively implicated in autism to explain deficits in executive and other higher-order functions related to cognition, language, sociability and emotion. |
2011-07-14 |
2023-08-12 |
rat |
Tania Rinaldi, Catherine Perrodin, Henry Markra. Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism. Frontiers in neural circuits. vol 2. 2011-07-14. PMID:18989389. |
we studied microcircuit alterations in the prefrontal cortex in the valproic acid rat model of autism and found that the layer 5 pyramidal neurons are connected to significantly more neighbouring neurons than in controls. |
2011-07-14 |
2023-08-12 |
rat |
Tania Rinaldi, Catherine Perrodin, Henry Markra. Hyper-connectivity and hyper-plasticity in the medial prefrontal cortex in the valproic Acid animal model of autism. Frontiers in neural circuits. vol 2. 2011-07-14. PMID:18989389. |
we propose that a number of deficits in autism such as sociability, attention, multi-tasking and repetitive behaviours, should be re-interpreted in the light of a hyper-functional prefrontal cortex. |
2011-07-14 |
2023-08-12 |
rat |
Hsien-Sung Huang, Iris Cheung, Schahram Akbaria. RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. vol 3. issue 4. 2011-01-14. PMID:20632321. |
rpp25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. |
2011-01-14 |
2023-08-12 |
mouse |
Hsien-Sung Huang, Iris Cheung, Schahram Akbaria. RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. vol 3. issue 4. 2011-01-14. PMID:20632321. |
here, we screened, in prefrontal cortex (pfc) of 15 subjects diagnosed with autism and 15 matched controls the expression of 44 transcripts that are either preferentially expressed in gamma-aminobutyric acidergic interneurons of the mature cortex or important for the development of inhibitory circuitry. |
2011-01-14 |
2023-08-12 |
mouse |
Basilis Zikopoulos, Helen Barba. Changes in prefrontal axons may disrupt the network in autism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 44. 2010-12-08. PMID:21048117. |
we investigated single axons and their ultrastructure in the white matter of postmortem human brain tissue below the anterior cingulate cortex (acc), orbitofrontal cortex (ofc), and lateral prefrontal cortex (lpfc), which are associated with attention, social interactions, and emotions, and have been consistently implicated in the pathology of autism. |
2010-12-08 |
2023-08-12 |
human |
John T Morgan, Gursharan Chana, Carlos A Pardo, Cristian Achim, Katerina Semendeferi, Jody Buckwalter, Eric Courchesne, Ian P Everal. Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism. Biological psychiatry. vol 68. issue 4. 2010-11-22. PMID:20674603. |
microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism. |
2010-11-22 |
2023-08-12 |
Not clear |
Jessica Griebling, Nancy J Minshew, Kimberly Bodner, Robin Libove, Rahul Bansal, Prasad Konasale, Matcheri S Keshavan, Antonio Harda. Dorsolateral prefrontal cortex magnetic resonance imaging measurements and cognitive performance in autism. Journal of child neurology. vol 25. issue 7. 2010-10-25. PMID:20097663. |
dorsolateral prefrontal cortex magnetic resonance imaging measurements and cognitive performance in autism. |
2010-10-25 |
2023-08-12 |
Not clear |
Michael V Lombardo, Bhismadev Chakrabarti, Edward T Bullmore, Susan A Sadek, Greg Pasco, Sally J Wheelwright, John Suckling, Simon Baron-Cohe. Atypical neural self-representation in autism. Brain : a journal of neurology. vol 133. issue Pt 2. 2010-03-16. PMID:20008375. |
in autism, ventromedial prefrontal cortex responded equally to self and other, while middle cingulate cortex responded more to other-mentalizing than self-mentalizing. |
2010-03-16 |
2023-08-12 |
Not clear |
Michael V Lombardo, Bhismadev Chakrabarti, Edward T Bullmore, Susan A Sadek, Greg Pasco, Sally J Wheelwright, John Suckling, Simon Baron-Cohe. Atypical neural self-representation in autism. Brain : a journal of neurology. vol 133. issue Pt 2. 2010-03-16. PMID:20008375. |
in autism, atypical neural self-representation was also apparent via reduced functional connectivity between ventromedial prefrontal cortex and areas associated with lower level embodied representations, such as ventral premotor and somatosensory cortex. |
2010-03-16 |
2023-08-12 |
Not clear |
Michael V Lombardo, Bhismadev Chakrabarti, Edward T Bullmore, Susan A Sadek, Greg Pasco, Sally J Wheelwright, John Suckling, Simon Baron-Cohe. Atypical neural self-representation in autism. Brain : a journal of neurology. vol 133. issue Pt 2. 2010-03-16. PMID:20008375. |
furthermore, the magnitude of neural self-other distinction in ventromedial prefrontal cortex was strongly related to the magnitude of early childhood social impairments in autism. |
2010-03-16 |
2023-08-12 |
Not clear |