| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huilin Zhu, Jun Li, Yuebo Fan, Xinge Li, Dan Huang, Sailing H. Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD): A functional near-infrared spectroscopy study. Biomedical optics express. vol 6. issue 3. 2015-03-23. PMID:25798296. |
in this study, functional near-infrared spectroscopy (fnirs) was applied to study the differences in activation and functional connectivity in the prefrontal cortex between children with autism spectrum disorder (asd) and typically developing (td) children. |
2015-03-23 |
2023-08-13 |
Not clear |
| Catherine Limperopoulos, Gevorg Chilingaryan, Nancy Sullivan, Nicolas Guizard, Richard L Robertson, Adré J du Plessi. Injury to the premature cerebellum: outcome is related to remote cortical development. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 3. 2014-10-03. PMID:23146968. |
we show highly significant associations between early signs of autism and dorsolateral prefrontal cortex volume (p < 0.001); gross motor scores and sensorimotor cortical volumes (p < 0.001); and cognitive and expressive language scores and premotor and mid-temporal cortical volumes (p < 0.001). |
2014-10-03 |
2023-08-12 |
Not clear |
| Jian-Ming Yang, Jing Zhang, Yan-Qin Yu, Shumin Duan, Xiao-Ming L. Postnatal development of 2 microcircuits involving fast-spiking interneurons in the mouse prefrontal cortex. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 1. 2014-09-25. PMID:23042741. |
disturbed development of the parvalbumin-positive fast-spiking (fs) interneurons in the prefrontal cortex (pfc) is closely associated with many neuropsychiatric disorders such as schizophrenia and autism. |
2014-09-25 |
2023-08-12 |
mouse |
| Xanthippi Konstantoudaki, Athanasia Papoutsi, Kleanthi Chalkiadaki, Panayiota Poirazi, Kyriaki Sidiropoulo. Modulatory effects of inhibition on persistent activity in a cortical microcircuit model. Frontiers in neural circuits. vol 8. 2014-09-24. PMID:24550786. |
imbalance of the excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as schizophrenia, autism and epilepsy, which also present with other cognitive deficits and symptoms associated with prefrontal cortical (pfc) dysfunction. |
2014-09-24 |
2023-08-12 |
Not clear |
| Amanda E Hernan, Abigail Alexander, Kyle R Jenks, Jeremy Barry, Pierre-Pascal Lenck-Santini, Elena Isaeva, Gregory L Holmes, Rod C Scot. Focal epileptiform activity in the prefrontal cortex is associated with long-term attention and sociability deficits. Neurobiology of disease. vol 63. 2014-09-19. PMID:24269731. |
we conclude that gabaergic blockade during early-life and resultant focal iis in the pfc disrupt neural networks and are associated with long-term consequences for behavior at a time when iis are no longer present, and thus may have important implications for adhd and autism spectrum disorder associated with childhood epilepsy. |
2014-09-19 |
2023-08-12 |
rat |
| Evan G Antzoulatos, Earl K Mille. Increases in functional connectivity between prefrontal cortex and striatum during category learning. Neuron. vol 83. issue 1. 2014-09-02. PMID:24930701. |
functional connectivity between the prefrontal cortex (pfc) and striatum (str) is thought critical for cognition and has been linked to conditions like autism and schizophrenia. |
2014-09-02 |
2023-08-13 |
monkey |
| Yu-Zhu Hong, Xue-Jun Zhang, Lin Hong, Qian-Ru Huang, Qiang W. [Influence of acupuncture of "Changqiang" (GV 1) on learning-memory ability and gap junction-related protein expression in the prefrontal cortex in autism rats]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 3. 2014-08-21. PMID:25069191. |
[influence of acupuncture of "changqiang" (gv 1) on learning-memory ability and gap junction-related protein expression in the prefrontal cortex in autism rats]. |
2014-08-21 |
2023-08-13 |
rat |
| Yu-Zhu Hong, Xue-Jun Zhang, Lin Hong, Qian-Ru Huang, Qiang W. [Influence of acupuncture of "Changqiang" (GV 1) on learning-memory ability and gap junction-related protein expression in the prefrontal cortex in autism rats]. Zhen ci yan jiu = Acupuncture research. vol 39. issue 3. 2014-08-21. PMID:25069191. |
to observe the effect of acupuncture stimulation of "changqiang" (gv 1) on learning-memory ability and gap junction-related protein expression in the prefrontal cortex in autism rats. |
2014-08-21 |
2023-08-13 |
rat |
| Jantine Ac Broek, Paul C Guest, Hassan Rahmoune, Sabine Bah. Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins. Molecular autism. vol 5. 2014-08-15. PMID:25126406. |
proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins. |
2014-08-15 |
2023-08-13 |
Not clear |
| Jantine Ac Broek, Paul C Guest, Hassan Rahmoune, Sabine Bah. Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins. Molecular autism. vol 5. 2014-08-15. PMID:25126406. |
the analysis focussed on prefrontal cortex and cerebellum as previous studies have found that these two brain regions are structurally and functionally connected, and they have been implicated in autism. |
2014-08-15 |
2023-08-13 |
Not clear |
| Vanessa M Vogan, Benjamin R Morgan, Wayne Lee, Tamara L Powell, Mary Lou Smith, Margot J Taylo. The neural correlates of visuo-spatial working memory in children with autism spectrum disorder: effects of cognitive load. Journal of neurodevelopmental disorders. vol 6. issue 1. 2014-07-24. PMID:25057329. |
research on the neural bases of cognitive deficits in autism spectrum disorder (asd) has shown that working memory (wm) difficulties are associated with abnormalities in the prefrontal cortex. |
2014-07-24 |
2023-08-13 |
Not clear |
| Alex A Ahmed, Brent C Vander Wy. Neural processing of intentional biological motion in unaffected siblings of children with autism spectrum disorder: an fMRI study. Brain and cognition. vol 83. issue 3. 2014-07-10. PMID:24128657. |
prior studies reported that typically developing children and adults, but not children with autism, show increased activation to incongruent actions (relative to congruent), within the psts and dorsolateral prefrontal cortex. |
2014-07-10 |
2023-08-12 |
Not clear |
| Rich Stoner, Maggie L Chow, Maureen P Boyle, Susan M Sunkin, Peter R Mouton, Subhojit Roy, Anthony Wynshaw-Boris, Sophia A Colamarino, Ed S Lein, Eric Courchesn. Patches of disorganization in the neocortex of children with autism. The New England journal of medicine. vol 370. issue 13. 2014-04-14. PMID:24670167. |
autism involves early brain overgrowth and dysfunction, which is most strongly evident in the prefrontal cortex. |
2014-04-14 |
2023-08-12 |
Not clear |
| Rich Stoner, Maggie L Chow, Maureen P Boyle, Susan M Sunkin, Peter R Mouton, Subhojit Roy, Anthony Wynshaw-Boris, Sophia A Colamarino, Ed S Lein, Eric Courchesn. Patches of disorganization in the neocortex of children with autism. The New England journal of medicine. vol 370. issue 13. 2014-04-14. PMID:24670167. |
as assessed on pathological analysis, an excess of neurons in the prefrontal cortex among children with autism signals a disturbance in prenatal development and may be concomitant with abnormal cell type and laminar development. |
2014-04-14 |
2023-08-12 |
Not clear |
| Basilis Zikopoulos, Helen Barba. Altered neural connectivity in excitatory and inhibitory cortical circuits in autism. Frontiers in human neuroscience. vol 7. 2013-10-07. PMID:24098278. |
we report preliminary findings of changes in autism in the ratio of distinct types of inhibitory neurons in prefrontal cortex, known to shape network dynamics and the balance of excitation and inhibition. |
2013-10-07 |
2023-08-12 |
Not clear |
| Naydu Marmolejo, Jesse Paez, Jonathan B Levitt, Liesl B Jone. Early postnatal lesion of the medial dorsal nucleus leads to loss of dendrites and spines in adult prefrontal cortex. Developmental neuroscience. vol 34. issue 6. 2013-09-19. PMID:23406908. |
our data are thus consistent with the hypothesis that the md plays a role in the development of the pfc and, therefore, may be a good model to begin to examine neurodevelopmental disorders such as autism and schizophrenia. |
2013-09-19 |
2023-08-12 |
rat |
| Tiffany D Rogers, Eric McKimm, Price E Dickson, Dan Goldowitz, Charles D Blaha, Guy Mittlema. Is autism a disease of the cerebellum? An integration of clinical and pre-clinical research. Frontiers in systems neuroscience. vol 7. 2013-05-30. PMID:23717269. |
while the etiology of autism is unknown, current research indicates that abnormalities of the cerebellum, now believed to be involved in cognitive function and the prefrontal cortex (pfc), are associated with autism. |
2013-05-30 |
2023-08-12 |
Not clear |
| Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesn. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS genetics. vol 8. issue 3. 2012-09-04. PMID:22457638. |
we focused on prefrontal cortex tissue where excess neuron numbers and cortical overgrowth are pronounced in the majority of autism cases. |
2012-09-04 |
2023-08-12 |
Not clear |
| Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesn. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS genetics. vol 8. issue 3. 2012-09-04. PMID:22457638. |
genes regulating cell cycle also exhibited autism-specific cnvs in dna derived from prefrontal cortex, and these genes were significantly associated with autism in genome-wide association study datasets. |
2012-09-04 |
2023-08-12 |
Not clear |
| Maggie L Chow, Tiziano Pramparo, Mary E Winn, Cynthia Carter Barnes, Hai-Ri Li, Lauren Weiss, Jian-Bing Fan, Sarah Murray, Craig April, Haim Belinson, Xiang-Dong Fu, Anthony Wynshaw-Boris, Nicholas J Schork, Eric Courchesn. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS genetics. vol 8. issue 3. 2012-09-04. PMID:22457638. |
our results suggest that cnvs and age-dependent gene expression changes in autism may reflect distinct pathological processes in the developing versus the mature autistic prefrontal cortex. |
2012-09-04 |
2023-08-12 |
Not clear |