| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Justin K Siemann, Brad A Grueter, Douglas G McMaho. Rhythms, Reward, and Blues: Consequences of Circadian Photoperiod on Affective and Reward Circuit Function. Neuroscience. vol 457. 2021-05-14. PMID:33385488. |
we next highlight how brain regions crucial for the serotoninergic system (i.e., dorsal raphe nucleus; drn), and dopaminergic (i.e., nucleus accumbens; nac and ventral tegmental area; vta) system are intertwined in overlapping circuitry, and play influential roles in the pathology of mood and reward-based disorders. |
2021-05-14 |
2023-08-13 |
human |
| Li Ma, Meng-Xue Tian, Qiao-Yi Sun, Na-Na Liu, Jian-Feng Dong, Ke Feng, Yu-Kang Wu, Yu-Xi Wang, Gui-Ying Wang, Wen Chen, Jia-Jie Xi, Jiu-Hong Kan. Fetal growth restriction mice are more likely to exhibit depression-like behaviors due to stress-induced loss of dopaminergic neurons in the VTA. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 10. 2021-04-30. PMID:32860269. |
moreover, fgr mice had significantly fewer dopaminergic neurons in the ventral tegmental area but no difference in serotoninergic neurons in the dorsal raphe. |
2021-04-30 |
2023-08-13 |
mouse |
| Hicham Chatoui, Abdellatif Abbaoui, Omar El Hiba, Ahmed Draoui, Halima Gamran. Neurobehavioral and neurophysiological effects of prolonged osmotic stress in rats: A focus on anxiety state and pain perception. Journal of chemical neuroanatomy. vol 106. 2021-04-06. PMID:32334030. |
this study examined the effect of prolonged water deprivation, in rat, on 5-ht and th- immuno-expression in dorsal raphe nucleus (drn), substantia nigra pars compacta (snc), ventral tegmental area (vta), and magnus raphe nucleus (mrn). |
2021-04-06 |
2023-08-13 |
rat |
| Marjorie R Levinstein, Kevin R Coffey, Russell G Marx, Atom J Lesiak, John F Neumaie. Stress induces divergent gene expression among lateral habenula efferent pathways. Neurobiology of stress. vol 13. 2020-12-22. PMID:33344721. |
the three major lhb outputs innervate dorsal raphe nucleus (drn), ventral tegmental area (vta), and the rostromedial tegmental nucleus (rmtg). |
2020-12-22 |
2023-08-13 |
rat |
| Tadashi Takada, Naoki Yoneda, Tetsushi Hirano, Kanoko Onaru, Youhei Mantani, Toshifumi Yokoyama, Hiroshi Kitagawa, Yoshiaki Tabuchi, Collins Nimako, Mayumi Ishizuka, Yoshinori Ikenaka, Nobuhiko Hosh. Combined exposure to dinotefuran and chronic mild stress counteracts the change of the emotional and monoaminergic neuronal activity induced by either exposure singly despite corticosterone elevation in mice. The Journal of veterinary medical science. vol 82. issue 3. 2020-11-16. PMID:31983702. |
in addition, serotonin (5-ht) and tryptophan hydroxylase 2 (tph2) of the dorsal raphe nuclei (drn) and median raphe nuclei (mrn) and tyrosine hydroxylase (th) of the ventral tegmental area and substantia nigra (sn) were evaluated immunohistochemically. |
2020-11-16 |
2023-08-13 |
mouse |
| Ozra Dehkordi, Jed E Rose, Martha I Dávila-García, Richard M Millis, Samar Ali Mirzaei, Kebreten F Manaye, Annapurni Jayam-Trout. Neuroanatomical Relationships between Orexin/Hypocretin-Containing Neurons/Nerve Fibers and Nicotine-Induced c-Fos-Activated Cells of the Reward-Addiction Neurocircuitry. Journal of alcoholism and drug dependence. vol 5. issue 4. 2020-10-01. PMID:29038792. |
however, there was infrequent contact between the orexinergic fibers and the th-expressing dopaminergic cells of vta, dorsal raphe nucleus (dr), posterior hypothalamus (da11), arcuate hypothalamic nucleus (da12) and periventricular areas (da14). |
2020-10-01 |
2023-08-13 |
mouse |
| Afra Wohlschläger, Harish Karne, Denis Jordan, Mark J Lowe, Stephen E Jones, Amit Anan. Spectral Dynamics of Resting State fMRI Within the Ventral Tegmental Area and Dorsal Raphe Nuclei in Medication-Free Major Depressive Disorder in Young Adults. Frontiers in psychiatry. vol 9. 2020-10-01. PMID:29867598. |
spectral dynamics of resting state fmri within the ventral tegmental area and dorsal raphe nuclei in medication-free major depressive disorder in young adults. |
2020-10-01 |
2023-08-13 |
Not clear |
| Amit Anand, Stephen E Jones, Mark Lowe, Harish Karne, Parashar Koiral. Resting State Functional Connectivity of Dorsal Raphe Nucleus and Ventral Tegmental Area in Medication-Free Young Adults With Major Depression. Frontiers in psychiatry. vol 9. 2020-10-01. PMID:30761028. |
resting state functional connectivity of dorsal raphe nucleus and ventral tegmental area in medication-free young adults with major depression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rao Fu, Qinghua Mei, Wanhong Zuo, Jing Li, Danielle Gregor, Alex Bekker, Jianghong Y. Low-dose ethanol excites lateral habenula neurons projecting to VTA, RMTg, and raphe. International journal of physiology, pathophysiology and pharmacology. vol 9. issue 6. 2020-09-30. PMID:29348799. |
these lhb neurons projected to the ventral tegmental area (vta), rostromedial tegmental nucleus (rmtg), and dorsal raphe. |
2020-09-30 |
2023-08-13 |
rat |
| Rao Fu, Qinghua Mei, Wanhong Zuo, Jing Li, Danielle Gregor, Alex Bekker, Jianghong Y. Low-dose ethanol excites lateral habenula neurons projecting to VTA, RMTg, and raphe. International journal of physiology, pathophysiology and pharmacology. vol 9. issue 6. 2020-09-30. PMID:29348799. |
these results indicate that the lhb neurons stimulated by a low-dose of ethanol project to the vta, rmtg, and dorsal raphe, and receive excitatory projections from the lateral hypothalamus. |
2020-09-30 |
2023-08-13 |
rat |
| Wen-Jun Zou, Yun-Long Song, Min-Yi Wu, Xiang-Tian Chen, Qiang-Long You, Qian Yang, Zheng-Yi Luo, Lang Huang, Yin Kong, Jing Feng, Dong-Xiang Fang, Xiao-Wen Li, Jian-Ming Yang, Lin Mei, Tian-Ming Ga. A discrete serotonergic circuit regulates vulnerability to social stress. Nature communications. vol 11. issue 1. 2020-09-14. PMID:32839452. |
here, we explored whether a serotonergic input from the dorsal raphe (dr) to ventral tegmental area (vta) influences vulnerability to social stress. |
2020-09-14 |
2023-08-13 |
Not clear |
| Gemma Huguet, Yasin Temel, Elisabet Kádár, Sylvana Pol, Joao Casaca-Carreira, Pilar Segura-Torres, Ali Jahanshah. Altered expression of dopaminergic cell fate regulating genes prior to manifestation of symptoms in a transgenic rat model of Huntington's disease. Brain research. vol 1712. 2020-09-11. PMID:30711400. |
previously, we have shown that the number of dopaminergic cells is increased in the dorsal raphe nucleus (drn) of hd patients and transgenic hd (tghd) rats during the manifestation phase of the disease; as well as in the substantia nigra pars compacta (snc) and ventral tegmental area (vta) of tghd rats. |
2020-09-11 |
2023-08-13 |
rat |
| Jin Zhang, Yong Wang, Yi Na Sun, Li Bo Li, Li Zhang, Yuan Guo, Tao Wang, Lu Yao, Li Chen, Jian Li. Blockade of calcium-permeable AMPA receptors in the lateral habenula produces increased antidepressant-like effects in unilateral 6-hydroxydopamine-lesioned rats compared to sham-lesioned rats. Neuropharmacology. vol 157. 2020-07-21. PMID:31251995. |
intra-lhb injection of naspm inhibited dopaminergic neurons in the anterior ventral tegmental area and serotonergic neurons in the dorsal raphe nucleus and excited dopaminergic neurons in the posterior ventral tegmental area (pvta) and serotonergic neurons in the median raphe nucleus (mrn), and lesioning the gabaergic rostromedial tegmental nucleus (rmtg) decreased the percentages of excited pvta dopaminergic neurons and mrn serotonergic neurons. |
2020-07-21 |
2023-08-13 |
rat |
| Romana Koprdova, Kristina Csatlosova, Barbora Durisova, Eszter Bogi, Magdalena Majekova, Eliyahu Dremencov, Mojmir Mac. Electrophysiology and Behavioral Assessment of the New Molecule SMe1EC2M3 as a Representative of the Future Class of Triple Reuptake Inhibitors. Molecules (Basel, Switzerland). vol 24. issue 23. 2020-04-14. PMID:31757051. |
electrophysiological investigations showed that sme1ec2m3 dose-dependently suppressed the excitability of 5-ht neurons of the dorsal raphe nucleus (drn), norepinephrine neurons of the locus coeruleus (lc), and dopamine neurons of the ventral tegmental area (vta). |
2020-04-14 |
2023-08-13 |
Not clear |
| Hui-Ling Wang, Shiliang Zhang, Jia Qi, Huikun Wang, Roger Cachope, Carlos A Mejias-Aponte, Jorge A Gomez, Gabriel E Mateo-Semidey, Gerard M J Beaudoin, Carlos A Paladini, Joseph F Cheer, Marisela Morale. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell reports. vol 26. issue 5. 2020-03-13. PMID:30699344. |
dorsal raphe dual serotonin-glutamate neurons drive reward by establishing excitatory synapses on vta mesoaccumbens dopamine neurons. |
2020-03-13 |
2023-08-13 |
Not clear |
| Hui-Ling Wang, Shiliang Zhang, Jia Qi, Huikun Wang, Roger Cachope, Carlos A Mejias-Aponte, Jorge A Gomez, Gabriel E Mateo-Semidey, Gerard M J Beaudoin, Carlos A Paladini, Joseph F Cheer, Marisela Morale. Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons. Cell reports. vol 26. issue 5. 2020-03-13. PMID:30699344. |
dorsal raphe (dr) serotonin neurons provide a major input to the ventral tegmental area (vta). |
2020-03-13 |
2023-08-13 |
Not clear |
| Jin Zhang, Shuxuan Lv, Guoyi Tang, Guanyun Bian, Yaxin Yang, Ruotong Li, Jie Yang, Jian Li. Activation of calcium-impermeable GluR2-containing AMPA receptors in the lateral habenula produces antidepressant-like effects in a rodent model of Parkinson's disease. Experimental neurology. vol 322. 2020-02-24. PMID:31499061. |
we further found that intra-lhb injection of (s)-ampa excited dopaminergic neurons in the anterior ventral tegmental area (avta) and serotonergic neurons in the dorsal raphe nucleus (drn), which increased release of da and 5-ht in the medial prefrontal cortex (mpfc), while nbqx induced the opposite effects. |
2020-02-24 |
2023-08-13 |
rat |
| Caleb J Browne, Andrew R Abela, Duong Chu, Zhaoxia Li, Xiaodong Ji, Evelyn K Lambe, Paul J Fletche. Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-11-25. PMID:30420603. |
dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition. |
2019-11-25 |
2023-08-13 |
mouse |
| Yue Li, Chun-Yue Li, Wang Xi, Sen Jin, Zuo-Hang Wu, Ping Jiang, Ping Dong, Xiao-Bin He, Fu-Qiang Xu, Shumin Duan, Yu-Dong Zhou, Xiao-Ming L. Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence. Neuron. vol 101. issue 4. 2019-08-26. PMID:30638902. |
rostral and caudal ventral tegmental area gabaergic inputs to different dorsal raphe neurons participate in opioid dependence. |
2019-08-26 |
2023-08-13 |
Not clear |
| Yue Li, Chun-Yue Li, Wang Xi, Sen Jin, Zuo-Hang Wu, Ping Jiang, Ping Dong, Xiao-Bin He, Fu-Qiang Xu, Shumin Duan, Yu-Dong Zhou, Xiao-Ming L. Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence. Neuron. vol 101. issue 4. 2019-08-26. PMID:30638902. |
both the ventral tegmental area (vta) and dorsal raphe nucleus (drn) are involved in affective control and reward-related behaviors. |
2019-08-26 |
2023-08-13 |
Not clear |