| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie A Kauer, Abigail M Polte. Two-Pronged Control of the Dorsal Raphe by the VTA. Neuron. vol 101. issue 4. 2019-08-15. PMID:30790535. |
(2019) distinguish two separable gabaergic projections from the ventral tegmental area (vta) to the dorsal raphe nucleus (drn), with differential μ-opioid receptor regulation, each targeting different postsynaptic neurons and promoting opposing behavioral states. |
2019-08-15 |
2023-08-13 |
Not clear |
| Sachie K Ogawa, Mitsuko Watabe-Uchid. Organization of dopamine and serotonin system: Anatomical and functional mapping of monosynaptic inputs using rabies virus. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:28476484. |
there is surprising similarity between the input to dopamine neurons in the ventral tegmental area (vta) and the input to serotonin neurons in the dorsal raphe (dr), suggesting functional interactions between these systems. |
2019-06-24 |
2023-08-13 |
Not clear |
| Su-Rong Yang, Zhen-Zhen Hu, Yan-Jia Luo, Ya-Nan Zhao, Huan-Xin Sun, Dou Yin, Chen-Yao Wang, Yu-Dong Yan, Dian-Ru Wang, Xiang-Shan Yuan, Chen-Bo Ye, Wei Guo, Wei-Min Qu, Yoan Cherasse, Michael Lazarus, Yu-Qiang Ding, Zhi-Li Huan. The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep. PLoS biology. vol 16. issue 4. 2019-03-27. PMID:29652889. |
the rostromedial tegmental nucleus (rmtg), also called the gabaergic tail of the ventral tegmental area, projects to the midbrain dopaminergic system, dorsal raphe nucleus, locus coeruleus, and other regions. |
2019-03-27 |
2023-08-13 |
rat |
| Diana Alarcón-Arís, Ariadna Recasens, Mireia Galofré, Iria Carballo-Carbajal, Nicolás Zacchi, Esther Ruiz-Bronchal, Rubén Pavia-Collado, Rosario Chica, Albert Ferrés-Coy, Marina Santos, Raquel Revilla, Andrés Montefeltro, Isabel Fariñas, Francesc Artigas, Miquel Vila, Analia Bortolozz. Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease. Molecular therapy : the journal of the American Society of Gene Therapy. vol 26. issue 2. 2019-02-12. PMID:29273501. |
following internalization of the conjugated oligonucleotides in monoamine neurons, reduced levels of endogenous α-synuclein mrna and protein were found in substantia nigra pars compacta (snc), ventral tegmental area (vta), dorsal raphe nucleus (dr), and locus coeruleus (lc). |
2019-02-12 |
2023-08-13 |
mouse |
| Seungrie Han, Soo Hyun Yang, Jin Yong Kim, Seojung Mo, Esther Yang, Ki Myung Song, Byung-Joo Ham, Naguib Mechawar, Gustavo Turecki, Hyun Woo Lee, Hyun Ki. Down-regulation of cholinergic signaling in the habenula induces anhedonia-like behavior. Scientific reports. vol 7. issue 1. 2018-09-05. PMID:28420875. |
to determine whether habenular cholinergic signaling is associated with regulation of dopamine neurons in the ventral tegmental area (vta) and serotonin neurons in the dorsal raphe nucleus (drn), we used chat::cre transgenic mice expressing the designer receptors exclusively activated by designer drugs (dreadd). |
2018-09-05 |
2023-08-13 |
mouse |
| Antony D Abraham, Harrison M Fontaine, Allisa J Song, Mackenzie M Andrews, Madison A Baird, Brigitte L Kieffer, Benjamin B Land, Charles Chavki. κ-Opioid Receptor Activation in Dopamine Neurons Disrupts Behavioral Inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 2. 2018-07-30. PMID:28649993. |
local inactivation of kor by injection of the long-acting antagonist nor-bni in the ventral tegmental area (vta), but not the infralimbic prefrontal cortex (pfc) or dorsal raphe nucleus (drn), prevented disruption of drl performance caused by systemic kor activation. |
2018-07-30 |
2023-08-13 |
mouse |
| Meghan Flanigan, Hossein Aleyasin, Aki Takahashi, Sam A Golden, Scott J Russ. An emerging role for the lateral habenula in aggressive behavior. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28499809. |
here, we discuss the evidence linking lhb function to aggression and its valence, arguing that strong lhb outputs to the ventral tegmental area (vta) and the dorsal raphe nucleus (drn) are likely to play roles in aggression and its rewarding components. |
2018-06-18 |
2023-08-13 |
Not clear |
| Susana S Correia, Ki A Goosen. Input-specific contributions to valence processing in the amygdala. Learning & memory (Cold Spring Harbor, N.Y.). vol 23. issue 10. 2018-01-16. PMID:27634144. |
here we review three of these areas, the basal forebrain, the dorsal raphe nucleus and the ventral tegmental area, and discuss how these may promote encoding of positive and negative valence within the bla. |
2018-01-16 |
2023-08-13 |
Not clear |
| Weixin Zhong, Yi Li, Qiru Feng, Minmin Lu. Learning and Stress Shape the Reward Response Patterns of Serotonin Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 37. 2017-09-29. PMID:28821671. |
both dopamine neurons in the ventral tegmental area and serotonin neurons in the dorsal raphe nucleus (drn) participate in reward processing. |
2017-09-29 |
2023-08-13 |
Not clear |
| Phillip M Baker, Thomas Jhou, Bo Li, Masayuki Matsumoto, Sheri J Y Mizumori, Marcus Stephenson-Jones, Aleksandra Vicenti. The Lateral Habenula Circuitry: Reward Processing and Cognitive Control. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 45. 2017-07-17. PMID:27911751. |
the lhb gets major inputs from the habenula-projecting globus pallidus and the mpfc, sending its efferents to the dopaminergic vta and snc, serotonergic dorsal raphe nuclei, and the gabaergic rostromedial tegmental nucleus. |
2017-07-17 |
2023-08-13 |
Not clear |
| Abdellatif Abbaoui, Omar E L Hiba, Halima Gamran. The neuronal basis of copper induced modulation of anxiety state in rat. Acta histochemica. vol 119. issue 1. 2017-01-11. PMID:27863709. |
our data report that cu enhanced 5ht innervation in the dorsal raphe nucleus (drn) together with a loss of th expression within the ventral tegmental area (vta), substantia nigra compacta (snc) and their subsequent outputs including the medial forebrain bundle (mfb) and striatum. |
2017-01-11 |
2023-08-13 |
rat |
| Jodi L Lukkes, Kevin J Norman, Shirisha Meda, Susan L Anderse. Sex differences in the ontogeny of CRF receptors during adolescent development in the dorsal raphe nucleus and ventral tegmental area. Synapse (New York, N.Y.). vol 70. issue 3. 2016-10-17. PMID:26696011. |
interactions between corticotropin-releasing factor (crf) and monoaminergic systems originating from the dorsal raphe nucleus (dr) and ventral tegmental area (vta) have been implicated in the etiology and pathophysiology of several stress-related neuropsychiatric disorders such as depression and substance abuse. |
2016-10-17 |
2023-08-13 |
rat |
| Marco Contreras, María E Riveros, Maricel Quispe, Cristián Sánchez, Guayec Perdomo, Fernando Torrealba, José L Valdé. The Histaminergic Tuberomamillary Nucleus Is Involved in Appetite for Sex, Water and Amphetamine. PloS one. vol 11. issue 2. 2016-07-12. PMID:26845170. |
however, during appetitive tests to obtain sex, or drug in amphetamine-conditioned rats, fos expression increased in most other ascending arousal system nuclei, including the orexin neurons in the lateral hypothalamus, dorsal raphe, locus coeruleus and laterodorsal tegmental neurons, but not in the ventral tegmental area, which showed no fos-ir increase in any of the 3 conditions. |
2016-07-12 |
2023-08-13 |
rat |
| Claudia Sagheddu, Sonia Aroni, Marta De Felice, Salvatore Lecca, Antonio Luchicchi, Miriam Melis, Anna Lisa Muntoni, Rosaria Romano, Enza Palazzo, Francesca Guida, Sabatino Maione, Marco Pisti. Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain. Neuropharmacology. vol 97. 2016-05-24. PMID:26113399. |
to assess whether these neurons display early changes in their activity that in the long-term might lead to chronicization, maladaptive plasticity and affective consequences, we carried out in vivo extracellular single unit recordings from serotonin neurons in the dorsal raphe nucleus (drn) and from dopamine neurons in ventral tegmental area (vta) in the spared nerve injury (sni) model of neuropathic pain in rats. |
2016-05-24 |
2023-08-13 |
rat |
| Jia Qi, Shiliang Zhang, Hui-Ling Wang, Huikun Wang, Jose de Jesus Aceves Buendia, Alexander F Hoffman, Carl R Lupica, Rebecca P Seal, Marisela Morale. A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons. Nature communications. vol 5. 2015-12-08. PMID:25388237. |
electrical stimulation of the dorsal raphe (dr) and ventral tegmental area (vta) activates the fibres of the same reward pathway but the phenotype of this pathway and the direction of the reward-relevant fibres have not been determined. |
2015-12-08 |
2023-08-13 |
Not clear |
| Lely A Quina, Lynne Tempest, Lydia Ng, Julie A Harris, Susan Ferguson, Thomas C Jhou, Eric E Turne. Efferent pathways of the mouse lateral habenula. The Journal of comparative neurology. vol 523. issue 1. 2015-07-21. PMID:25099741. |
by using retrograde tract tracing with cholera toxin subunit b, we show that lhb neurons projecting to the hypothalamus, vta, median raphe, caudal dorsal raphe, and pontine central gray reside in characteristic, but sometimes overlapping regions of the lhb. |
2015-07-21 |
2023-08-13 |
mouse |
| Chris A Oosterhof, Mostafa El Mansari, Pierre Blie. Acute effects of brexpiprazole on serotonin, dopamine, and norepinephrine systems: an in vivo electrophysiologic characterization. The Journal of pharmacology and experimental therapeutics. vol 351. issue 3. 2015-02-17. PMID:25225185. |
in addition, the effects on 5-ht1a autoreceptors in the dorsal raphe nucleus (drn) and d2 autoreceptors in the ventral tegmental area (vta) were compared with those of aripiprazole, an agent in wide clinical use. |
2015-02-17 |
2023-08-13 |
Not clear |
| Franck Chenu, Stacey Shim, Mostafa El Mansari, Pierre Blie. Role of melatonin, serotonin 2B, and serotonin 2C receptors in modulating the firing activity of rat dopamine neurons. Journal of psychopharmacology (Oxford, England). vol 28. issue 2. 2014-10-24. PMID:24189440. |
the present study was aimed at investigating the in vivo effects of repeated administration of melatonin (40 mg/kg/day), the 5-ht(2c) receptor antagonist sb 242084 (0.5 mg/kg/day), the selective 5-ht(2b) receptor antagonist ly 266097 (0.6 mg/kg/day) and their combination on ventral tegmental area (vta) dopamine (da), locus coeruleus (lc) norepinephrine (ne), and dorsal raphe nucleus (drn) serotonin (5-ht) firing activity. |
2014-10-24 |
2023-08-12 |
rat |
| Franck Chenu, Mostafa El Mansari, Pierre Blie. Electrophysiological effects of repeated administration of agomelatine on the dopamine, norepinephrine, and serotonin systems in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 2. 2013-10-17. PMID:22871919. |
the effects of 2-day and 14-day administration of agomelatine were investigated on the activity of ventral tegmental area (vta) dopamine (da), locus coeruleus (lc) norepinephrine (ne), and dorsal raphe nucleus (drn) 5-ht neurons using in vivo electrophysiology in rats. |
2013-10-17 |
2023-08-12 |
rat |
| Aron S Buchman, Sukriti Nag, Joshua M Shulman, Andrew S P Lim, Veronique G J M VanderHorst, Sue E Leurgans, Julie A Schneider, David A Bennet. Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 13. 2013-05-13. PMID:23038629. |
we measured neuron density in the substantia nigra, ventral tegmental area, locus coeruleus, and dorsal raphe, along with postmortem indices of lewy body disease, alzheimer's disease and cerebrovascular pathologies. |
2013-05-13 |
2023-08-12 |
Not clear |