| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Dahan, H Husum, O Mnie-Filali, J Arnt, P Hertel, N Haddjer. Effects of bifeprunox and aripiprazole on rat serotonin and dopamine neuronal activity and anxiolytic behaviour. Journal of psychopharmacology (Oxford, England). vol 23. issue 2. 2009-07-28. PMID:18515444. |
using in-vivo electrophysiological and behavioural paradigms in the rat, the effects of bifeprunox and aripiprazole were assessed on ventral tegmental area (vta) dopamine and dorsal raphe serotonin (5-ht) cell activity and on foot shock-induced ultrasonic vocalisation (usv). |
2009-07-28 |
2023-08-12 |
rat |
| Ramez Ghanbari, Mostafa El Mansari, Mohammed Shahid, Pierre Blie. Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 19. issue 3. 2009-05-20. PMID:19116183. |
this study electrophysiologically characterized the in vivo effects of asenapine at dorsal raphe nucleus (drn) and hippocampus serotonin-1a (5-ht(1a)), ventral tegmental area d(2), locus coeruleus 5-ht(2a,) and alpha(2)-adrenergic receptors in anesthetized rats. |
2009-05-20 |
2023-08-12 |
rat |
| Polina Petkova-Kirova, Angelina Rakovska, Galina Zaekova, Chiara Ballini, Laura Della Corte, Radomir Radomirov, Anikó Vágvölgy. Stimulation by neurotensin of dopamine and 5-hydroxytryptamine (5-HT) release from rat prefrontal cortex: possible role of NTR1 receptors in neuropsychiatric disorders. Neurochemistry international. vol 53. issue 6-8. 2009-03-09. PMID:18835308. |
these effects are possibly mediated by interactions of neurotensin with neurons releasing da or 5-ht, projecting to the pfc from the ventrotegmental area (vta) and from the dorsal raphe nuclei (drn), respectively. |
2009-03-09 |
2023-08-12 |
rat |
| Samüel Deurveilher, Henry Lo, Jeremy A Murphy, Joan Burns, Kazue Semb. Differential c-Fos immunoreactivity in arousal-promoting cell groups following systemic administration of caffeine in rats. The Journal of comparative neurology. vol 498. issue 5. 2006-10-18. PMID:16917819. |
at any dose used, caffeine induced little or no c-fos expression in cholinergic neurons of the basal forebrain and mesopontine tegmentum; dopaminergic neurons of the ventral tegmental area, central gray, and substantia nigra pars compacta; and serotonergic neurons in the dorsal raphe nucleus. |
2006-10-18 |
2023-08-12 |
rat |
| Juan A Flores, Beatriz Galan-Rodriguez, Susana Ramiro-Fuentes, Emilio Fernandez-Espej. Role for dopamine neurons of the rostral linear nucleus and periaqueductal gray in the rewarding and sensitizing properties of heroin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 7. 2006-09-05. PMID:16292327. |
dopamine neurons of the nearby vta and dorsal raphe were not affected, as revealed by cell counting. |
2006-09-05 |
2023-08-12 |
rat |
| Paul L A Gabbott, Tracy A Warner, Paul R L Jays, Phillip Salway, Sarah J Busb. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. The Journal of comparative neurology. vol 492. issue 2. 2006-01-23. PMID:16196030. |
injections of the retrograde pathway tracer wheat germ agglutinin conjugated with horseradish peroxidase (wga-hrp) were made into dorsal/ventral striatum (ds/vs), basolateral amygdala (bla), mediodorsal thalamus (md), lateral hypothalamus (lh), mediolateral septum, dorsolateral periaqueductal gray, dorsal raphe, ventral tegmental area, parabrachial nucleus, nucleus tractus solitarius, rostral/caudal ventrolateral medulla, or thoracic spinal cord (sc). |
2006-01-23 |
2023-08-12 |
rat |
| Cristine L Czachowsk. Manipulations of serotonin function in the nucleus accumbens core produce differential effects on ethanol and sucrose seeking and intake. Alcoholism, clinical and experimental research. vol 29. issue 7. 2006-01-11. PMID:16046869. |
it is hypothesized that serotonin affects ethanol-directed behaviors by interacting with this system via projections from the dorsal raphe to the nucleus accumbens and vta. |
2006-01-11 |
2023-08-12 |
Not clear |
| J L W Bosboom, D Stoffers, E Ch Wolter. Cognitive dysfunction and dementia in Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 10-11. 2005-01-26. PMID:15480840. |
parkinson's disease (pd) is a slowly progressive neurodegenerative disorder mainly characterized by degeneration of dopaminergic neurons in the substantia nigra and the ventral tegmental area, in combination with a varying loss of central noradrenergic (locus coeruleus), cholinergic (nucleus basalis of meynert) and serotonergic (dorsal raphe nuclei) integrity, leading to a multitude of motor and non-motor behavioral disturbances. |
2005-01-26 |
2023-08-12 |
Not clear |
| G Garcia, P Tagliaferro, A Ferri, A M Evangelista de Duffard, R Duffard, A Brusc. Study of tyrosine hydroxylase immunoreactive neurons in neonate rats lactationally exposed to 2,4-dichlorophenoxyacetic Acid. Neurotoxicology. vol 25. issue 6. 2005-01-14. PMID:15474613. |
dorsal raphe serotonin (5-ht) projections to sn and vta were also studied by 5-ht transporter (5-htt) immunostaining and results were quantified by image analysis. |
2005-01-14 |
2023-08-12 |
rat |
| Gilbert J Kirouac, Sa Li, Gehan Mabrou. GABAergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus. The Journal of comparative neurology. vol 469. issue 2. 2004-03-18. PMID:14694532. |
gabaergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus. |
2004-03-18 |
2023-08-12 |
rat |
| Gilbert J Kirouac, Sa Li, Gehan Mabrou. GABAergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus. The Journal of comparative neurology. vol 469. issue 2. 2004-03-18. PMID:14694532. |
previous studies have shown that neurons in the ventral tegmental area (vta) and substantia nigra (sn) project to the ventrolateral periaqueductal gray (pagvl) and dorsal raphe nucleus (dr). |
2004-03-18 |
2023-08-12 |
rat |
| Olga A Sergeeva, Tatiana M Korotkova, Annette Scherer, Ritchie E Brown, Helmut L Haa. Co-expression of non-selective cation channels of the transient receptor potential canonical family in central aminergic neurones. Journal of neurochemistry. vol 85. issue 6. 2003-07-10. PMID:12787073. |
all serotonergic neurones of the dorsal raphe (dr), the majority of histaminergic (tuberomamillary nucleus; tmn) and dopaminergic cells of the ventral tegmental area (vta), as well as some gabaergic neurones from the vta, expressed at least one variant of trpc channels. |
2003-07-10 |
2023-08-12 |
rat |
| J V Trinh, D L Nehrenberg, J P R Jacobsen, M G Caron, W C Wetse. Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699766. |
in wt mice, methylphenidate induced fos-like immunoreactivity (fos-li) in the mesostriatal and mesolimbocortical da pathways that included the anterior olfactory nucleus, frontal association cortex, orbitofrontal cortex, cingulate cortex, caudate-putamen, globus pallidus, claustrum, lateral septum, nucleus accumbens, basolateral and central nuclei of the amygdala, bed nucleus of stria terminalis, subthalamic nucleus, substantia nigra, ventral tegmental area, and dorsal raphe. |
2003-06-16 |
2023-08-12 |
mouse |
| Karin Schwartz, Gal Yadid, Abraham Weizman, Moshe Rehav. Decreased limbic vesicular monoamine transporter 2 in a genetic rat model of depression. Brain research. vol 965. issue 1-2. 2003-05-01. PMID:12591135. |
the vmat2 mrna level was analyzed by in situ hybridization, in the vta, snc and the dorsal raphe (dr) nucleus. |
2003-05-01 |
2023-08-12 |
rat |
| Yasushi Ishida, Hiroyuki Hashiguchi, Ryuichiro Takeda, Yuta Ishizuka, Yoshio Mitsuyama, Hiroshi Kannan, Toshikazu Nishimori, Daiichiro Nakahar. Conditioned-fear stress increases Fos expression in monoaminergic and GABAergic neurons of the locus coeruleus and dorsal raphe nuclei. Synapse (New York, N.Y.). vol 45. issue 1. 2002-08-06. PMID:12112413. |
we examined the effects of conditioned-fear (cf) stress following mild footshock (fs) as unconditioned stress on fos expression in the monoaminergic and gabaergic neurons of the ventral tegmental area (vta), locus coeruleus (lc), and dorsal raphe nucleus (dr) in rats. |
2002-08-06 |
2023-08-12 |
rat |
| E C Wolter. Intrinsic and extrinsic psychosis in Parkinson's disease. Journal of neurology. vol 248 Suppl 3. 2002-03-27. PMID:11697684. |
these symptoms are caused by a progressive abnormal degeneration of the dopamine (da) producing cells in the substantia nigra (sn) and ventral tegmentum area (vta) in combination with an interindividual fluctuating degree of decay in the noradrenergic (locus coeruleus), cholinergic forebrain (nucleus basalis of meynert) and serotoninergic (dorsal raphe nuclei) systems. |
2002-03-27 |
2023-08-12 |
Not clear |
| S Chatelin, R Wehrlé, P Mercier, D Morello, C Sotelo, M J Webe. Neuronal promoter of human aromatic L-amino acid decarboxylase gene directs transgene expression to the adult floor plate and aminergic nuclei induced by the isthmus. Brain research. Molecular brain research. vol 97. issue 2. 2002-03-21. PMID:11750071. |
a large degree of co-expression was observed with tyrosine-hydroxylase (th) in the sn and vta, and with serotonin (5-ht) in the dorsal raphe nucleus. |
2002-03-21 |
2023-08-12 |
mouse |
| M Shirane, K Nakamur. Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597608. |
local perfusion of mecamylamine, a nicotinic acetylcholine (nach) and n-methyl-d-aspartate (nmda) receptor antagonist, into the ventral tegmental area (vta) and dorsal raphe nucleus (drn) completely blocked da and 5-ht release, respectively, in the pfc elicited by orally administered aniracetam. |
2002-01-14 |
2023-08-12 |
rat |
| Y Ishida, M Nakamura, K Ebihara, K Hoshino, H Hashiguchi, Y Mitsuyama, T Nishimori, D Nakahar. Immunohistochemical characterisation of Fos-positive cells in brainstem monoaminergic nuclei following intracranial self-stimulation of the medial forebrain bundle in the rat. The European journal of neuroscience. vol 13. issue 8. 2001-07-12. PMID:11328353. |
icss induced a significant but different degree of increase in the number of fos-immunopositive (fos+) cells in the six brainstem monoaminergic nuclei examined, which included the ventral tegmental area (vta), substantia nigra pars compacta (snc), dorsal raphe nucleus (dr), median raphe nucleus (mr), locus coeruleus (lc), and a7 noradrenaline cells. |
2001-07-12 |
2023-08-12 |
rat |
| E C Wolter. Psychiatric complications in Parkinson's disease. Journal of neural transmission. Supplementum. issue 60. 2001-04-12. PMID:11205148. |
parkinson's disease (pd) is caused by an abnormal degeneration of the dopamine (da) producing cells in the substantia nigra (sn) and ventral tegmentum area (vta) in combination with a varying decay of the noradrenergic (locus coeruleus), cholinergic forebrain (nucleus basalis of meynert) and serotoninergic (dorsal raphe nuclei) systems, leading to a multitude of motor and non-motor behavioral disturbances, known as parkinsonism. |
2001-04-12 |
2023-08-12 |
Not clear |