| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L E Krahn, J L Black, M H Silbe. Narcolepsy: new understanding of irresistible sleep. Mayo Clinic proceedings. vol 76. issue 2. 2001-03-15. PMID:11213307. |
the role of hypocretins in narcolepsy is unclear but intriguing because the cell bodies are restricted to the lateral hypothalamus, a brain region long associated with sleep regulation, with neuronal widespread projections to areas including the locus ceruleus, ventral tegmental area, amygdala, and dorsal raphe. |
2001-03-15 |
2023-08-12 |
Not clear |
| T Chiba, T Kayahara, K Nakan. Efferent projections of infralimbic and prelimbic areas of the medial prefrontal cortex in the Japanese monkey, Macaca fuscata. Brain research. vol 888. issue 1. 2001-03-01. PMID:11146055. |
moderately to weakly projected areas were the intermediate and lateral parts of the agranular insular cortex, orbital part of area 12, agranular and dysgranular part of the temporal pole cortex (tpa-g), auditory temporal cortex, lateral and medial (ms) septal nuclei, bed nucleus of the stria terminalis, diagonal band of broca, substantia innominata, and medial preoptic area, dorsomedial, lateral, and posterior hypothalamic nuclei, magnocellular lateral basal and lateral amygdaloid nuclei, paratenial, paraventricular (pv), inter-antero-medial (iam), reticular, central medial (cem), parafascicular (pf) and limitans nuclei of the thalamus, lateral habenular nucleus, pedunculo-pontine nucleus, dorsal part of the lateral lemniscal nucleus, ventral tegmental area (vta), dorsal raphe, superior central nucleus, medial and lateral parabrachial nuclei (pbl) and nucleus locus coeruleus (lc). |
2001-03-01 |
2023-08-12 |
monkey |
| F Lejeune, M J Milla. Pindolol excites dopaminergic and adrenergic neurons, and inhibits serotonergic neurons, by activation of 5-HT1A receptors. The European journal of neuroscience. vol 12. issue 9. 2000-11-07. PMID:10998110. |
herein, we examined its influence upon electrical activity of serotonergic, dopaminergic and adrenergic perikarya in the dorsal raphe nucleus (drn), ventral tegmental area (vta) and locus coeruleus (lc) of anaesthetized rats. |
2000-11-07 |
2023-08-12 |
rat |
| M J Millan, A Gobert, J M Rivet, A Adhumeau-Auclair, D Cussac, A Newman-Tancredi, A Dekeyne, J P Nicolas, F Lejeun. Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram. The European journal of neuroscience. vol 12. issue 3. 2000-05-22. PMID:10762339. |
citalopram inhibited the firing rate of serotonergic neurons in dorsal raphe nucleus, but not of dopaminergic neurons in the ventral tegmental area, nor adrenergic neurons in the locus coeruleus. |
2000-05-22 |
2023-08-12 |
human |
| J Gervais, C Rouillar. Dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra. Synapse (New York, N.Y.). vol 35. issue 4. 2000-03-13. PMID:10657038. |
dorsal raphe stimulation differentially modulates dopaminergic neurons in the ventral tegmental area and substantia nigra. |
2000-03-13 |
2023-08-12 |
rat |
| C P Stephenson, G E Hunt, A N Topple, I S McGrego. The distribution of 3,4-methylenedioxymethamphetamine "Ecstasy"-induced c-fos expression in rat brain. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426541. |
significant c-fos expression was also seen in the ventral tegmental area, amidst the cell bodies of mesolimbic and mesocortical dopamine neurons, and in the median and dorsal raphe, where the serotonergic innervation of the forebrain originates. |
1999-09-09 |
2023-08-12 |
human |
| E M Nikulina, J E Marchand, R M Kream, K A Micze. Behavioral sensitization to cocaine after a brief social stress is accompanied by changes in fos expression in the murine brainstem. Brain research. vol 810. issue 1-2. 1999-01-29. PMID:9813326. |
fos-like immunoreactive (fos-li) cell nuclei were analyzed in the ventral tegmental area (vta), dorsal raphe nucleus (dr), periaqueductal grey area (pag) and locus coeruleus (lc). |
1999-01-29 |
2023-08-12 |
mouse |
| F Lejeune, M J Milla. Induction of burst firing in ventral tegmental area dopaminergic neurons by activation of serotonin (5-HT)1A receptors: WAY 100,635-reversible actions of the highly selective ligands, flesinoxan and S 15535. Synapse (New York, N.Y.). vol 30. issue 2. 1998-11-16. PMID:9723787. |
this study examined the influence of the highly selective 5-ht1a receptor ligands, flesinoxan, s 15535, and way 100,635, upon the electrical activity of dopaminergic neurons in the ventral tegmental area (vta), as compared to serotonergic neurons in the dorsal raphe nucleus (drn) of anesthetized rats. |
1998-11-16 |
2023-08-12 |
rat |
| S A Burchett, M J Banno. Serotonin, dopamine and norepinephrine transporter mRNAs: heterogeneity of distribution and response to 'binge' cocaine administration. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387868. |
sert mrna was quantified within the dorsal raphe (dr) and the median raphe (mr), dat mrna within the ventral tegmental area -substantia nigra (vta-sn) region and net mrna within the locus coeruleus (lc). |
1998-02-11 |
2023-08-12 |
rat |
| P A Broderick, C F Pheli. I. Serotonin (5-HT) within dopamine reward circuits signals open-field behavior. II. Basis for 5-HT--DA interaction in cocaine dysfunctional behavior. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168262. |
dorsal raphe (dr) or the proximal da somatodendrites, vta. |
1997-07-21 |
2023-08-12 |
Not clear |
| J S Lonstein, J M Ster. Role of the midbrain periaqueductal gray in maternal nurturance and aggression: c-fos and electrolytic lesion studies in lactating rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 9. 1997-05-22. PMID:9113892. |
in contrast, this pattern was not evident in the rostral pag, where the highest fos levels occurred in nonsuckled dams, or in five other brainstem sites with either no group differences (peripenduncular, dorsal raphe, and pontine nuclei) or negligible fos (ventral tegmental area, spinal trigeminal nuclei). |
1997-05-22 |
2023-08-12 |
rat |
| F Lejeune, A Newman-Tancredi, V Audinot, M J Milla. Interactions of (+)- and (-)-8- and 7-hydroxy-2-(di-n-propylamino)tetralin at human (h)D3, hD2 and h serotonin1A receptors and their modulation of the activity of serotoninergic and dopaminergic neurones in rats. The Journal of pharmacology and experimental therapeutics. vol 280. issue 3. 1997-04-11. PMID:9067310. |
in our study, we evaluated the influence of their (+)- and (-) isomers on the electrical activity of serotoninergic neurones of the dorsal raphe nucleus (drn), which bear 5-ht1a autoreceptors, and of dopaminergic neurones of the ventral tegmental area (vta), which possess inhibitory d3 and d2 receptors. |
1997-04-11 |
2023-08-12 |
human |
| L A Chahl, J Leah, T Herdegen, L Trueman, A M Lynch-Fram. Distribution of c-Fos in guinea-pig brain following morphine withdrawal. Brain research. vol 717. issue 1-2. 1996-11-13. PMID:8738262. |
in the animals that were treated with morphine and withdrawn with either naloxone or naltrexone, c-fos was expressed in neurons in many brain areas, including the frontal and cingulate cortices, olfactory tubercles, ventral pallidum, nucleus accumbens, habenular, paraventricular thalamic nucleus, septal and arcuate nuclei, lateral and posterior hypothalamic areas, ventral tegmental area, central grey, dorsal raphe nucleus, locus coeruleus, raphe magnus, lateral paragigantocellular nucleus and solitary tract nucleus. |
1996-11-13 |
2023-08-12 |
Not clear |
| B Ford, C J Holmes, L Mainville, B E Jone. GABAergic neurons in the rat pontomesencephalic tegmentum: codistribution with cholinergic and other tegmental neurons projecting to the posterior lateral hypothalamus. The Journal of comparative neurology. vol 363. issue 2. 1996-07-16. PMID:8642069. |
the double-labeled gad+/ct+ cells were commonly found ipsilaterally within 1) the deep mesencephalic reticular field, codistributed with putative glutamatergic projection neurons; 2) the ventral tegmental area, substantia nigra compacta, and retrorubral field, codistributed with dopaminergic projection neurons; 3) dorsal raphe, codistributed with serotonergic projection neurons; and 4) laterodorsal and pedunculopontine tegmental nuclei, codistributed with and in similar proportion to cholinergic projection cells (20-30% in ldtg). |
1996-07-16 |
2023-08-12 |
rat |
| R Lew, K E Sabol, C Chou, G L Vosmer, J Richards, L S Seide. Methylenedioxymethamphetamine-induced serotonin deficits are followed by partial recovery over a 52-week period. Part II: Radioligand binding and autoradiography studies. The Journal of pharmacology and experimental therapeutics. vol 276. issue 2. 1996-07-03. PMID:8632359. |
no effect of mdma was observed over lateral hypothalamus, substantia nigra and ventral tegmental area, or over serotonergic cell bodies such as dorsal raphe and median raphe. |
1996-07-03 |
2023-08-12 |
rat |
| W J McBride, J M Murphy, G J Gatto, A D Levy, K Yoshimoto, L Lumeng, T K L. CNS mechanisms of alcohol self-administration. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1995-06-22. PMID:7748340. |
neurochemical and neuropharmacological studies were undertaken to examine the possible involvement of the ventral tegmental area (vta) dopamine (da) system and the dorsal raphe nucleus (drn) serotonin (5-ht) system in regulating oral alcohol self-administration. |
1995-06-22 |
2023-08-12 |
rat |
| M Fujita, S Shimada, K Fukuchi, M Tohyama, T Nishimur. Distribution of cocaine recognition sites in rat brain: in vitro and ex vivo autoradiography with [125I]RTI-55. Journal of chemical neuroanatomy. vol 7. issue 1-2. 1995-01-31. PMID:7802967. |
further, in the presence of clomipramine, a selective ligand for 5htt, [125i]rti-55 binding was remarkably inhibited in the midline and lateral geniculate nuclei of the thalamus, the hypothalamic nuclei, the superior colliculus, the dorsal raphe nucleus, and the facial nucleus, while [125i]rti-55 binding remained in the olfactory tubercle, the caudate putamen, the accumbens nucleus, the substantia nigra compact part, the subthalamic nucleus, and the ventral tegmental area. |
1995-01-31 |
2023-08-12 |
rat |
| M Gobbi, M C Regondi, M Pompeiano, J M Palacios, T Mennin. Differential effects of 5,7-dihydroxytryptamine-induced serotoninergic degeneration of 5-HT1A receptors and 5-HT uptake sites in the rat brain. Journal of chemical neuroanatomy. vol 7. issue 1-2. 1995-01-31. PMID:7802971. |
in the caudate putamen these binding sites were significantly decreased only 14 days after the lesion, whereas the ventral tegmental area (or the enclosed median forebrain bundle), the dorsal raphe (mainly the ventral portion) and the median raphe maintained their high density of serotonin uptake sites even after 14 days. |
1995-01-31 |
2023-08-12 |
rat |
| D Wirtshafter, T R Stratford, M R Pitze. Studies on the behavioral activation produced by stimulation of GABAB receptors in the median raphe nucleus. Behavioural brain research. vol 59. issue 1-2. 1994-05-19. PMID:8155296. |
hyperactivity was produced by lower doses of baclofen, at shorter latencies, when the drug was injected into the mr than when it applied to the dorsal raphe nucleus (dr) or the ventral tegmental area (vta). |
1994-05-19 |
2023-08-12 |
Not clear |
| M J Eaton, K P Gudehithlu, T Quach, C P Silvia, M Hadjiconstantinou, N H Nef. Distribution of aromatic L-amino acid decarboxylase mRNA in mouse brain by in situ hybridization histology. The Journal of comparative neurology. vol 337. issue 4. 1994-02-24. PMID:7904615. |
after treatment with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), the signal disappeared in the substantia nigra, decreased somewhat in the ventral tegmental area, and remained unchanged in the dorsal raphe nucleus. |
1994-02-24 |
2023-08-12 |
mouse |