| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Malishkevich, N Amram, G Hacohen-Kleiman, I Magen, E Giladi, I Goze. Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies. Translational psychiatry. vol 5. 2015-09-09. PMID:25646590. |
activity-dependent neuroprotective protein (adnp) is a most frequent autism spectrum disorder (asd)-associated gene and the only protein significantly decreasing in the serum of alzheimer's disease (ad) patients. |
2015-09-09 |
2023-08-13 |
mouse |
| Szabolcs Kér. Social influence on associative learning: double dissociation in high-functioning autism, early-stage behavioural variant frontotemporal dementia and Alzheimer's disease. Cortex; a journal devoted to the study of the nervous system and behavior. vol 54. 2014-12-15. PMID:24709075. |
social influence on associative learning: double dissociation in high-functioning autism, early-stage behavioural variant frontotemporal dementia and alzheimer's disease. |
2014-12-15 |
2023-08-13 |
Not clear |
| Maud Cochet-Bissuel, Philippe Lory, Arnaud Montei. The sodium leak channel, NALCN, in health and disease. Frontiers in cellular neuroscience. vol 8. 2014-06-24. PMID:24904279. |
in addition, genes encoding nalcn, nlf- 1, unc-79, and unc-80 proteins may be susceptibility loci for several diseases including bipolar disorder, schizophrenia, alzheimer's disease, autism, epilepsy, alcoholism, cardiac diseases and cancer. |
2014-06-24 |
2023-08-13 |
human |
| Hiroshi Marut. Herbal therapeutics that block the oncogenic kinase PAK1: a practical approach towards PAK1-dependent diseases and longevity. Phytotherapy research : PTR. vol 28. issue 5. 2014-06-19. PMID:23943274. |
over 35 years research on paks, rac/cdc42(p21)-activated kinases, comes of age, and in particular pak1 has been well known to be responsible for a variety of diseases such as cancer (mainly solid tumors), alzheimer's disease, acquired immune deficiency syndrome and other viral/bacterial infections, inflammatory diseases (asthma and arthritis), diabetes (type 2), neurofibromatosis, tuberous sclerosis, epilepsy, depression, schizophrenia, learning disability, autism, etc. |
2014-06-19 |
2023-08-12 |
caenorhabditis_elegans |
| C J Westmar. What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders. Molecular psychiatry. vol 18. issue 4. 2014-04-21. PMID:22925831. |
accumulating evidence suggests that dysregulated levels of amyloid β-protein precursor (app) and its catabolites contribute to the impaired synaptic plasticity and seizure incidence observed in several neurological disorders, including alzheimer's disease, fragile x syndrome, down's syndrome, autism, epilepsy and parkinson's disease as well as in brain injury. |
2014-04-21 |
2023-08-12 |
Not clear |
| Joaquín Fernández-Irigoyen, María V Zelaya, Enrique Santamarí. Applying mass spectrometry-based qualitative proteomics to human amygdaloid complex. Frontiers in cellular neuroscience. vol 8. 2014-04-01. PMID:24688456. |
brain diseases including depression, epilepsy, autism, schizophrenia, and alzheimer's disease, have been associated with amygdala dysfunction. |
2014-04-01 |
2023-08-12 |
human |
| Lydia Barth, Rosmarie Sütterlin, Markus Nenniger, Kaspar E Vog. Functional differentiation of stem cell-derived neurons from different murine backgrounds. Frontiers in cellular neuroscience. vol 8. 2014-03-06. PMID:24600351. |
murine stem cell-derived neurons have been used to study a wide variety of neuropsychiatric diseases with a hereditary component, ranging from autism to alzheimer's. |
2014-03-06 |
2023-08-12 |
mouse |
| Michael Berk, Gin S Malhi, Laura J Gray, Olivia M Dea. The promise of N-acetylcysteine in neuropsychiatry. Trends in pharmacological sciences. vol 34. issue 3. 2013-09-20. PMID:23369637. |
this review summarises the areas where the mechanisms of action of nac overlap with known pathophysiological elements, and offers a précis of current literature regarding the use of nac in disorders including cocaine, cannabis, and smoking addictions, alzheimer's and parkinson's diseases, autism, compulsive and grooming disorders, schizophrenia, depression, and bipolar disorder. |
2013-09-20 |
2023-08-12 |
Not clear |
| C J Carte. Toxoplasmosis and Polygenic Disease Susceptibility Genes: Extensive Toxoplasma gondii Host/Pathogen Interactome Enrichment in Nine Psychiatric or Neurological Disorders. Journal of pathogens. vol 2013. 2013-03-28. PMID:23533776. |
susceptibility genes for multiple sclerosis, alzheimer's disease, schizophrenia, bipolar disorder, depression, childhood obesity, parkinson's disease, attention deficit hyperactivity disorder (p from 8.01e - 05 (adhd) to 1.22e - 71) (multiple sclerosis), and autism (p = 0.013), but not anorexia or chronic fatigue are highly enriched in the human arm of this interactome and 18 (adhd) to 33% (ms) of the susceptibility genes relate to it. |
2013-03-28 |
2023-08-12 |
human |
| George Bartzoki. Neuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22306524. |
similarly, psychotropic treatments ranging from lithium and antipsychotics to serotonin reuptake inhibitors (ssris) and acetylcholinesterase inhibitors have been shown to be efficacious in a wide spectrum of psychiatric disorders ranging from autism, schizophrenia (sz), depression, and bipolar disorder (bd) to alzheimer's disease (ad). |
2012-12-20 |
2023-08-12 |
human |
| Patrick F Sullivan, Mark J Daly, Michael O'Donova. Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nature reviews. Genetics. vol 13. issue 8. 2012-09-25. PMID:22777127. |
in this review, we discuss the genetics of nine cardinal psychiatric disorders (namely, alzheimer's disease, attention-deficit hyperactivity disorder, alcohol dependence, anorexia nervosa, autism spectrum disorder, bipolar disorder, major depressive disorder, nicotine dependence and schizophrenia). |
2012-09-25 |
2023-08-12 |
Not clear |
| Eleonora Palma, Luca Conti, Cristina Roseti, Cristina Limatol. Novel approaches to study the involvement of α7-nAChR in human diseases. Current drug targets. vol 13. issue 5. 2012-09-17. PMID:22300023. |
the alpha7 nicotinic acetylcholine receptor (α7 nachr) is widely distributed in the human brain and has been implicated in a number of human central nervous system (cns) diseases, including alzheimer's and parkinson's disease, schizophrenia and autism. |
2012-09-17 |
2023-08-12 |
human |
| Michel Paradi. Principles underlying the Bilingual Aphasia Test (BAT) and its uses. Clinical linguistics & phonetics. vol 25. issue 6-7. 2011-10-20. PMID:21675824. |
it has been used not only with aphasia but also with any condition that results in language impairment (alzheimer's, autism, cerebellar lesions, developmental language disorders, mild cognitive impairment, motor neuron disease, multiple sclerosis, parkinson's, vascular dementia, etc.). |
2011-10-20 |
2023-08-12 |
Not clear |
| M S Nandhu, George Naijil, Soman Smijin, S Jayanarayanan, C S Paulos. Opioid system functional regulation in neurological disease management. Journal of neuroscience research. vol 88. issue 15. 2011-01-25. PMID:20734417. |
there is increasing evidence to suggest a role for the opioid system in the control of pathophysiology of neurological disorders (alzheimer's, parkinson's, and huntington's diseases, spinal cord injury, epilepsy, hypoxia, and autism). |
2011-01-25 |
2023-08-12 |
Not clear |
| Cara J Westmark, Pamela R Westmark, James S Malte. Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures. Journal of Alzheimer's disease : JAD. vol 20. issue 4. 2010-10-12. PMID:20413855. |
amyloid-beta protein precursor (abetapp) is overexpressed in alzheimer's disease (ad), down syndrome (ds), autism, and fragile x syndrome. |
2010-10-12 |
2023-08-12 |
mouse |
| R Tabarés-Seisdedos, J L R Rubenstei. Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer. Molecular psychiatry. vol 14. issue 6. 2009-08-28. PMID:19204725. |
molecular genetics and developmental studies have identified 21 genes in this region (adra1a, arhgef10, chrna2, chrna6, chrnb3, dkk4, dpysl2, egr3, fgf17, fgf20, fgfr1, fzd3, ldl, nat2, nef3, nrg1, pcm1, plat, ppp3cc, sfrp1 and vmat1/slc18a1) that are most likely to contribute to neuropsychiatric disorders (schizophrenia, autism, bipolar disorder and depression), neurodegenerative disorders (parkinson's and alzheimer's disease) and cancer. |
2009-08-28 |
2023-08-12 |
mouse |
| Samuel-Datum Moscavitch, Martine Szyper-Kravitz, Yehuda Shoenfel. Autoimmune pathology accounts for common manifestations in a wide range of neuro-psychiatric disorders: the olfactory and immune system interrelationship. Clinical immunology (Orlando, Fla.). vol 130. issue 3. 2009-03-03. PMID:19097945. |
in this review we discuss a possible inter-relationship between olfactory impairment, autoimmunity and neurological/psychiatric symptoms in several diseases affecting the central nervous system (cns) such as parkinson, alzheimer's disease, autism, schizophrenia, multiple sclerosis and neuropsychiatric lupus erythematosus. |
2009-03-03 |
2023-08-12 |
human |
| Mijail Demian Serruya, Michael J Kahan. Techniques and devices to restore cognition. Behavioural brain research. vol 192. issue 2. 2008-09-30. PMID:18539345. |
executive planning, the ability to direct and sustain attention, language and several types of memory may be compromised by conditions such as stroke, traumatic brain injury, cancer, autism, cerebral palsy and alzheimer's disease. |
2008-09-30 |
2023-08-12 |
Not clear |
| Michiko Fujimoto, Shusaku Uchida, Toshio Watanuki, Yusuke Wakabayashi, Koji Otsuki, Toshio Matsubara, Masatomo Suetsugi, Hiromasa Funato, Yoshifumi Watanab. Reduced expression of glyoxalase-1 mRNA in mood disorder patients. Neuroscience letters. vol 438. issue 2. 2008-09-19. PMID:18455873. |
glo1 has been suggested to be involved in anxiety disorders, autism, and alzheimer's disease. |
2008-09-19 |
2023-08-12 |
human |
| Cherie R Percaccio, Autumn L Pruette, Shilpa T Mistry, Yeting H Chen, Michael P Kilgar. Sensory experience determines enrichment-induced plasticity in rat auditory cortex. Brain research. vol 1174. 2008-03-10. PMID:17854780. |
this conclusion may be beneficial to clinical populations with sensory gating and cholinergic abnormalities, including individuals with autism, schizophrenia, and alzheimer's disease. |
2008-03-10 |
2023-08-12 |
rat |