| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Concetta Miniaci, Elvira De Leonibu. Missing the egocentric spatial reference: a blank on the map. F1000Research. vol 7. 2019-11-20. PMID:29568496. |
deficits in spatial memory come with age-related cognitive decline, are marked in mild cognitive impairment (mci) and alzheimer's disease (ad), and are associated with cognitive deficits in autism. |
2019-11-20 |
2023-08-13 |
Not clear |
| Daniel Linares, Rafael Marin-Campos, Josep Dalmau, Albert Compt. Validation of motion perception of briefly displayed images using a tablet. Scientific reports. vol 8. issue 1. 2019-10-24. PMID:30375459. |
motion perception of briefly displayed images has been reported to be abnormal in clinical populations afflicted with schizophrenia, major depression, autism, alzheimer's disease and epilepsy. |
2019-10-24 |
2023-08-13 |
human |
| Donald R C McLachlan, Catherine Bergeron, Peter N Alexandrov, William J Walsh, Aileen I Pogue, Maire E Percy, Theodore P A Kruck, Zhide Fang, Nathan M Sharfman, Vivian Jaber, Yuhai Zhao, Wenhong Li, Walter J Luki. Aluminum in Neurological and Neurodegenerative Disease. Molecular neurobiology. vol 56. issue 2. 2019-07-11. PMID:30706368. |
neurological diseases examined were alzheimer's disease (ad; n = 186), ataxia friedreich's type (aft; n = 6), amyotrophic lateral sclerosis (als; n = 16), autism spectrum disorder (asd; n = 26), dialysis dementia syndrome (dds; n = 27), down's syndrome (ds; trisomy, 21; n = 24), huntington's chorea (hc; n = 15), multiple infarct dementia (mid; n = 19), multiple sclerosis (ms; n = 23), parkinson's disease (pd; n = 27), and prion disease (prd; n = 11) that included bovine spongiform encephalopathy (bse; "mad cow disease"), creutzfeldt-jakob disease (cjd) and gerstmann-straussler-sheinker syndrome (gss), progressive multifocal leukoencephalopathy (pml; n = 11), progressive supranuclear palsy (psp; n = 24), schizophrenia (scz; n = 21), a young control group (ycg; n = 22; mean age, 10.2 ± 6.1 year), and an aged control group (acg; n = 53; mean age, 71.4 ± 9.3 year). |
2019-07-11 |
2023-08-13 |
human |
| Pavlos Rigas, Leonidas J Leontiadis, Panagiotis Tsakanikas, Irini Skalior. Spontaneous Neuronal Network Persistent Activity in the Neocortex: A(n) (Endo)phenotype of Brain (Patho)physiology. Advances in experimental medicine and biology. vol 988. 2019-05-01. PMID:28971403. |
abnormal synaptic homeostasis in the cerebral cortex represents a risk factor for both psychiatric and neurodegenerative disorders, from autism and schizophrenia to alzheimer's disease. |
2019-05-01 |
2023-08-13 |
Not clear |
| Emma J Bubb, Claudia Metzler-Baddeley, John P Aggleto. The cingulum bundle: Anatomy, function, and dysfunction. Neuroscience and biobehavioral reviews. vol 92. 2019-02-11. PMID:29753752. |
meanwhile, non-invasive imaging implicates the cingulum bundle in executive control, emotion, pain (dorsal cingulum), and episodic memory (parahippocampal cingulum), while clinical studies reveal cingulum abnormalities in numerous conditions, including schizophrenia, depression, post-traumatic stress disorder, obsessive compulsive disorder, autism spectrum disorder, mild cognitive impairment, and alzheimer's disease. |
2019-02-11 |
2023-08-13 |
rat |
| Irene Y Huang, Yu-Luan Hsu, Chien-Chang Chen, Mei-Fang Chen, Zhi-Hong Wen, Hsien-Ting Huang, Ingrid Y Li. Excavatolide-B Enhances Contextual Memory Retrieval via Repressing the Delayed Rectifier Potassium Current in the Hippocampus. Marine drugs. vol 16. issue 11. 2019-01-22. PMID:30366389. |
memory retrieval dysfunction is a symptom of schizophrenia, autism spectrum disorder (asd), and absence epilepsy (ae), as well as an early sign of alzheimer's disease. |
2019-01-22 |
2023-08-13 |
Not clear |
| Julia R Wilkerson, Joseph P Albanesi, Kimberly M Hube. Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease. Seminars in cell & developmental biology. vol 77. 2018-12-11. PMID:28969983. |
we also discuss accumulating evidence linking dysregulation of arc and mglur-ltd in human cognitive disorders such as intellectual disability, autism and alzheimer's disease. |
2018-12-11 |
2023-08-13 |
human |
| Jiani Yin, Wu Chen, Hongxing Yang, Mingshan Xue, Christian P Schaa. Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes. Scientific reports. vol 7. 2018-10-10. PMID:28045139. |
the alpha7 nicotinic acetylcholine receptor, encoded by the chrna7 gene, has been implicated in various psychiatric and behavioral disorders, including schizophrenia, bipolar disorder, epilepsy, autism, alzheimer's disease, and parkinson's disease, and is considered a potential target for therapeutic intervention. |
2018-10-10 |
2023-08-13 |
mouse |
| Nasrin Nikzad, Zahra Karam. Label-free colorimetric sensor for sensitive detection of choline based on DNAzyme-choline oxidase coupling. International journal of biological macromolecules. vol 115. 2018-10-09. PMID:29665395. |
changes in choline levels can be associated with diseases such as alzheimer, parkinson, huntington, fatty liver, interstitial lung abnormalities, autism and so on. |
2018-10-09 |
2023-08-13 |
Not clear |
| Ayşe Demirha. The effect of feature selection on multivariate pattern analysis of structural brain MR images. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). vol 47. 2018-08-27. PMID:29609811. |
in this study, the effectiveness of determining the most relevant features for mvpa of the brain mr images are examined using relieff and minimum redundancy maximum relevance (mrmr) algorithms to predict the alzheimer's disease (ad), schizophrenia, autism, and attention deficit and hyperactivity disorder (adhd). |
2018-08-27 |
2023-08-13 |
human |
| Shlomo Sragovich, Avia Merenlender-Wagner, Illana Goze. ADNP Plays a Key Role in Autophagy: From Autism to Schizophrenia and Alzheimer's Disease. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 39. issue 11. 2018-07-23. PMID:28940660. |
adnp plays a key role in autophagy: from autism to schizophrenia and alzheimer's disease. |
2018-07-23 |
2023-08-13 |
Not clear |
| Shlomo Sragovich, Avia Merenlender-Wagner, Illana Goze. ADNP Plays a Key Role in Autophagy: From Autism to Schizophrenia and Alzheimer's Disease. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 39. issue 11. 2018-07-23. PMID:28940660. |
thus, linking autophagy and adnp is proposed as a major target for intervention in brain diseases from autism to alzheimer's disease (ad) and our findings introduce autophagy as a possible novel target for treating schizophrenia. |
2018-07-23 |
2023-08-13 |
Not clear |
| Dongting Zhangsun, Xiaopeng Zhu, Quentin Kaas, Yong Wu, David J Craik, J Michael McIntosh, Sulan Lu. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype. Neuropharmacology. vol 127. 2018-07-11. PMID:28416445. |
nicotinic acetylcholine receptor (nachr) subtypes exhibit distinct neuropharmacological properties that are involved in a range of neuropathological conditions, including pain, addiction, epilepsy, autism, schizophrenia, tourette's syndrome, alzheimer's and parkinson's diseases, as well as many types of cancer. |
2018-07-11 |
2023-08-13 |
human |
| Stephen Grossber. Acetylcholine Neuromodulation in Normal and Abnormal Learning and Memory: Vigilance Control in Waking, Sleep, Autism, Amnesia and Alzheimer's Disease. Frontiers in neural circuits. vol 11. 2018-07-09. PMID:29163063. |
acetylcholine neuromodulation in normal and abnormal learning and memory: vigilance control in waking, sleep, autism, amnesia and alzheimer's disease. |
2018-07-09 |
2023-08-13 |
Not clear |
| Cheng-Ta Lee, Min-Hua Kao, Wen-Hsien Hou, Yu-Ting Wei, Chin-Lin Chen, Cheng-Chang Lie. Causal Evidence for the Role of Specific GABAergic Interneuron Types in Entorhinal Recruitment of Dentate Granule Cells. Scientific reports. vol 6. 2018-06-26. PMID:27830729. |
abnormalities of gabaergic circuits in the dg are associated with several brain disorders, including epilepsy, autism, schizophrenia, and alzheimer disease. |
2018-06-26 |
2023-08-13 |
Not clear |
| Renata Solimini, Maria Concetta Rotolo, Simona Pichini, Roberta Pacific. Neurological Disorders in Medical Use of Cannabis: An Update. CNS & neurological disorders drug targets. vol 16. issue 5. 2018-05-01. PMID:28412919. |
medical cannabis is increasingly used as a treatment or adjunct treatment with different levels of efficacy in several neurological disorders or related symptoms (such as multiple sclerosis, autism, parkinson and alzheimer disease, tourette's syndrome, huntington's disease, neuropathic pain, epilepsy, headache), as well as in other medical conditions (e.g. |
2018-05-01 |
2023-08-13 |
Not clear |
| Z M Saygin, D Kliemann, J E Iglesias, A J W van der Kouwe, E Boyd, M Reuter, A Stevens, K Van Leemput, A McKee, M P Frosch, B Fischl, J C Augustinac. High-resolution magnetic resonance imaging reveals nuclei of the human amygdala: manual segmentation to automatic atlas. NeuroImage. vol 155. 2018-04-20. PMID:28479476. |
we applied this atlas to two publicly available datasets (adni and abide) with standard resolution t1 data, used individual volumetric data of the amygdala nuclei as the measure and found that our atlas i) discriminates between alzheimer's disease participants and age-matched control participants with 84% accuracy (auc=0.915), and ii) discriminates between individuals with autism and age-, sex- and iq-matched neurotypically developed control participants with 59.5% accuracy (auc=0.59). |
2018-04-20 |
2023-08-13 |
human |
| Nadia Regina Rodrigues, Ana Paula Ferreira de Souz. Occurrence of glyphosate and AMPA residues in soy-based infant formula sold in Brazil. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. vol 35. issue 4. 2018-04-16. PMID:29267136. |
recently, glyphosate and its metabolite aminomethylphosphonic acid (ampa) have been identified as possible contributors to the emergence of various diseases such as autism, parkinson's and alzheimer's diseases, as well as cancer. |
2018-04-16 |
2023-08-13 |
Not clear |
| Richa Hanamsagar, Mark D Alter, Carina S Block, Haley Sullivan, Jessica L Bolton, Staci D Bilb. Generation of a microglial developmental index in mice and in humans reveals a sex difference in maturation and immune reactivity. Glia. vol 65. issue 9. 2018-04-12. PMID:28618077. |
next, a microglial developmental index (mdi) generated from gene expression patterns obtained from purified mouse microglia, was applied to human brain transcriptome datasets to test the hypothesis that variability in microglial development is associated with human diseases such as alzheimer's and autism where microglia have been suggested to play a role. |
2018-04-12 |
2023-08-13 |
mouse |
| Parakalan Rangarajan, Aparna Karthikeyan, S T Dhee. Role of dietary phenols in mitigating microglia-mediated neuroinflammation. Neuromolecular medicine. vol 18. issue 3. 2018-04-03. PMID:27465151. |
studies show that these natural phenols inhibit key signaling pathways in activated microglia such as the nfκb, mapk and jak-stat that trigger microglia-mediated inflammation in various neuropathological conditions such as injury, infection, stroke, autism and neurodegenerative diseases, i.e., alzheimer's disease and parkinson's disease. |
2018-04-03 |
2023-08-13 |
Not clear |