| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xi Zhao, Jianhua Zou, Huibin Li, Emmanuel Dellandrea, Ioannis A Kakadiaris, Liming Che. Automatic 2.5-D Facial Landmarking and Emotion Annotation for Social Interaction Assistance. IEEE transactions on cybernetics. vol 46. issue 9. 2018-02-07. PMID:26316289. |
people with low vision, alzheimer's disease, and autism spectrum disorder experience difficulties in perceiving or interpreting facial expression of emotion in their social lives. |
2018-02-07 |
2023-08-13 |
Not clear |
| Laura Moody, Hong Chen, Yuan-Xiang Pa. Early-Life Nutritional Programming of Cognition-The Fundamental Role of Epigenetic Mechanisms in Mediating the Relation between Early-Life Environment and Learning and Memory Process. Advances in nutrition (Bethesda, Md.). vol 8. issue 2. 2017-12-21. PMID:28298276. |
diseases characterized by learning and memory impairments, such as autism, schizophrenia, and alzheimer disease, are hypothesized to be attributed in part to environmental factors, and evidence suggests that the etiology of these conditions may date back to very early life. |
2017-12-21 |
2023-08-13 |
Not clear |
| Disha Shah, Ines Blockx, Georgios A Keliris, Firat Kara, Elisabeth Jonckers, Marleen Verhoye, Annemie Van der Linde. Cholinergic and serotonergic modulations differentially affect large-scale functional networks in the mouse brain. Brain structure & function. vol 221. issue 6. 2017-09-28. PMID:26195064. |
the cholinergic system is involved in cognitive functions and is impaired in, e.g., alzheimer's disease, while the serotonergic system is involved in emotional and introspective functions and is impaired in, e.g., alzheimer's disease, depression and autism. |
2017-09-28 |
2023-08-13 |
mouse |
| Keith Fluegg. Does MeCP2 deficiency in autism confer protection against later development of Alzheimer's disease? A reply to Oberman and Pascual-Leone (2014). Medical hypotheses. vol 92. 2017-07-21. PMID:27241247. |
does mecp2 deficiency in autism confer protection against later development of alzheimer's disease? |
2017-07-21 |
2023-08-13 |
Not clear |
| Magdalena Gąssowska, Irena Baranowska-Bosiacka, Joanna Moczydłowska, Maciej Tarnowski, Anna Pilutin, Izabela Gutowska, Lidia Strużyńska, Dariusz Chlubek, Agata Adamczy. Perinatal exposure to lead (Pb) promotes Tau phosphorylation in the rat brain in a GSK-3β and CDK5 dependent manner: Relevance to neurological disorders. Toxicology. vol 347-349. 2016-08-18. PMID:27012722. |
hyperphosphorylation of tau is involved in the pathomechanism of neurological disorders such as alzheimer's, parkinson's diseases as well as autism. |
2016-08-18 |
2023-08-13 |
rat |
| Illana Goze. Activity-dependent neuroprotective protein (ADNP): from autism to Alzheimer's disease. SpringerPlus. vol 4. issue Suppl 1. 2016-07-07. PMID:27386198. |
activity-dependent neuroprotective protein (adnp): from autism to alzheimer's disease. |
2016-07-07 |
2023-08-13 |
Not clear |
| Heeok Hong, Byung Sun Kim, Heh-In I. Pathophysiological Role of Neuroinflammation in Neurodegenerative Diseases and Psychiatric Disorders. International neurourology journal. vol 20. issue Suppl 1. 2016-05-27. PMID:27230456. |
brain diseases and disorders such as alzheimer disease, parkinson disease, depression, schizophrenia, autism, and addiction lead to reduced quality of daily life through abnormal thoughts, perceptions, emotional states, and behavior. |
2016-05-27 |
2023-08-13 |
human |
| Zhihong Chen, Bruce D Trap. Microglia and neuroprotection. Journal of neurochemistry. vol 136 Suppl 1. 2016-05-26. PMID:25693054. |
microglia can also protect the cns by promoting neurogenesis, clearing debris, and suppressing inflammation in diseases such as stroke, autism, and alzheimer's. |
2016-05-26 |
2023-08-13 |
Not clear |
| Madeleine S Goodkind, Virginia E Sturm, Elizabeth A Ascher, Suzanne M Shdo, Bruce L Miller, Katherine P Rankin, Robert W Levenso. Emotion recognition in frontotemporal dementia and Alzheimer's disease: A new film-based assessment. Emotion (Washington, D.C.). vol 15. issue 4. 2016-04-08. PMID:26010574. |
deficits in recognizing others' emotions are reported in many psychiatric and neurological disorders, including autism, schizophrenia, behavioral variant frontotemporal dementia (bvftd) and alzheimer's disease (ad). |
2016-04-08 |
2023-08-13 |
human |
| Deepmala, John Slattery, Nihit Kumar, Leanna Delhey, Michael Berk, Olivia Dean, Charles Spielholz, Richard Fry. Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review. Neuroscience and biobehavioral reviews. vol 55. 2016-04-04. PMID:25957927. |
in this systematic review we find favorable evidence for the use of nac in several psychiatric and neurological disorders, particularly autism, alzheimer's disease, cocaine and cannabis addiction, bipolar disorder, depression, trichotillomania, nail biting, skin picking, obsessive-compulsive disorder, schizophrenia, drug-induced neuropathy and progressive myoclonic epilepsy. |
2016-04-04 |
2023-08-13 |
Not clear |
| Yoshiaki Omura, Dominic Lu, Marilyn K Jones, Ahdallah Nihrane, Harsha Duvvi, Yasuhiro Shimotsuura, Motomu Ohk. Early Detection of Autism (ASD) by a Non-invasive Quick Measurement of Markedly Reduced Acetylcholine & DHEA and Increased β-Amyloid (1-42), Asbestos (Chrysotile), Titanium Dioxide, Al, Hg & often Coexisting Virus Infections (CMV, HPV 16 and 18), Bacterial Infections etc. in the Brain and Corresponding Safe Individualized Effective Treatment. Acupuncture & electro-therapeutics research. vol 40. issue 3. 2016-03-10. PMID:26829843. |
simple non- invasive measurement of various molecules through pupils & head of diagnosed or suspected autism patients indicated that in autism patients following changes were often found: 1) acetylcholine is markedly reduced; 2) alzheimer's disease markers (i.e. |
2016-03-10 |
2023-08-13 |
Not clear |
| Yoshiaki Omura, Dominic Lu, Marilyn K Jones, Ahdallah Nihrane, Harsha Duvvi, Yasuhiro Shimotsuura, Motomu Ohk. Early Detection of Autism (ASD) by a Non-invasive Quick Measurement of Markedly Reduced Acetylcholine & DHEA and Increased β-Amyloid (1-42), Asbestos (Chrysotile), Titanium Dioxide, Al, Hg & often Coexisting Virus Infections (CMV, HPV 16 and 18), Bacterial Infections etc. in the Brain and Corresponding Safe Individualized Effective Treatment. Acupuncture & electro-therapeutics research. vol 40. issue 3. 2016-03-10. PMID:26829843. |
in addition the optimal doses of vitamin d3 and taurine may play an important role in the future treatment of autism, alzheimer's disease and memory disturbances by significantly increasing acetylcholine and dhea levels, enhancing the excretion of toxic substances in the urine, as well as having an anticancer effect. |
2016-03-10 |
2023-08-13 |
Not clear |
| Illana Gozes, Adva Yeheskel, Metsada Pasmanik-Cho. Activity-dependent neuroprotective protein (ADNP): a case study for highly conserved chordata-specific genes shaping the brain and mutated in cancer. Journal of Alzheimer's disease : JAD. vol 45. issue 1. 2016-02-29. PMID:25428252. |
the recent finding of activity-dependent neuroprotective protein (adnp) as a protein decreased in serum of patients with alzheimer's disease (ad) compared to controls, alongside with the discovery of adnp mutations in autism and coupled with the original description of cancer mutations, ignited an interest for a comparative analysis of adnp with other ad/autism/cancer-associated genes. |
2016-02-29 |
2023-08-13 |
Not clear |
| Reshma Alokam, Sarthak Singhal, Geetha Sai Srivathsav, Sowmya Garigipati, Sripriya Puppala, Dharmarajan Sriram, Yogeeswari Peruma. Design of dual inhibitors of ROCK-I and NOX2 as potential leads for the treatment of neuroinflammation associated with various neurological diseases including autism spectrum disorder. Molecular bioSystems. vol 11. issue 2. 2016-02-29. PMID:25465055. |
inhibition of both rho kinase (rock-i) and nadph oxidase (nox2) to treat neuroinflammation could be very effective in the treatment of progressive neurological diseases like alzheimer's disease, autism spectral disorder, and fragile x syndrome. |
2016-02-29 |
2023-08-13 |
human |
| Nathan G Skene, Seth G N Gran. Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment. Frontiers in neuroscience. vol 10. 2016-02-09. PMID:26858593. |
genetic susceptibility primarily affected microglia in alzheimer's and multiple sclerosis; was shared between interneurons and pyramidal neurons in autism and schizophrenia; while intellectual disabilities and epilepsy were attributable to a range of cell-types, with the strongest enrichment in interneurons. |
2016-02-09 |
2023-08-13 |
mouse |
| Xingxiu Pan, Xinxia Chang, Celeste Leung, Zikai Zhou, Feng Cao, Wei Xie, Zhengping Ji. PAK1 regulates cortical development via promoting neuronal migration and progenitor cell proliferation. Molecular brain. vol 8. 2016-01-19. PMID:26043730. |
pak1 is also implicated in a number of neurodevelopmental and neurodegenerative diseases, including autism, intellectual disability and alzheimer's disease. |
2016-01-19 |
2023-08-13 |
Not clear |
| Illana Gozes, Yanina Ivashko-Pachim. ADNP: in search for molecular mechanisms and innovative therapeutic strategies for frontotemporal degeneration. Frontiers in aging neuroscience. vol 7. 2015-11-20. PMID:26578950. |
activity-dependent neuroprotective protein (adnp) is deregulated in alzheimer's disease (ad) and in schizophrenia and mutated in autism. |
2015-11-20 |
2023-08-13 |
mouse |
| Jeffrey N Savas, Luís F Ribeiro, Keimpe D Wierda, Rebecca Wright, Laura A DeNardo-Wilke, Heather C Rice, Ingrid Chamma, Yi-Zhi Wang, Roland Zemla, Mathieu Lavallée-Adam, Kristel M Vennekens, Matthew L O'Sullivan, Joseph K Antonios, Elizabeth A Hall, Olivier Thoumine, Alan D Attie, John R Yates, Anirvan Ghosh, Joris de Wi. The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors. Neuron. vol 87. issue 4. 2015-11-16. PMID:26291160. |
sorcs1 mutations have been associated with autism and alzheimer disease, suggesting that perturbed receptor trafficking contributes to synaptic-composition and -function defects underlying synaptopathies. |
2015-11-16 |
2023-08-13 |
Not clear |
| Clare Paterson, Amanda J La. Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood. PloS one. vol 9. issue 8. 2015-11-09. PMID:25093331. |
neuregulin 3 (nrg3), a specific ligand for erbb4 and a neuronal-enriched neurotrophin is implicated in the genetic predisposition to a broad spectrum of neurodevelopmental, neurocognitive and neuropsychiatric disorders, including alzheimer's disease, autism and schizophrenia. |
2015-11-09 |
2023-08-13 |
mouse |
| Maegan M Weltzin, Marvin K Schult. Desformylflustrabromine Modulates α4β2 Neuronal Nicotinic Acetylcholine Receptor High- and Low-Sensitivity Isoforms at Allosteric Clefts Containing the β2 Subunit. The Journal of pharmacology and experimental therapeutics. vol 354. issue 2. 2015-09-15. PMID:26025967. |
alterations in expression patterns of α4β2 nicotinic acetylcholine receptors have been demonstrated to alter cholinergic neurotransmission and are implicated in neurologic disorders, including autism, nicotine addiction, alzheimer's disease, and parkinson's disease. |
2015-09-15 |
2023-08-13 |
xenopus_laevis |