| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chun-Xia Wang, Yuan Ding, Di Wu, Ji-Jie Xing, Li-Yuan Fen. [Cluster needling of scalp points improves cognitive dysfunction by regulating NF-κB activity in rats with Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 48. issue 6. 2023-06-29. PMID:37385790. |
to observe the effect of cluster needling of scalp points on nuclear transcription factor kappa b p65 (nf-κb p65)，nf-κb inhibitory protein α (ikbα)，β secretase 1 (bace1)，beta-amyloid protein (aβ) and hippocampal morphology in alzheimer's disease (ad) rats，so as to reveal its mechanism underlying improvement of ad. |
2023-06-29 |
2023-08-14 |
rat |
| Lan Xiao, Xuyu Yang, Vinay Kumar Sharma, Daniel Abebe, Y Peng Lo. Hippocampal delivery of neurotrophic factor-α1/carboxypeptidase E gene prevents neurodegeneration, amyloidosis, memory loss in Alzheimer's Disease male mice. Molecular psychiatry. 2023-06-27. PMID:37369719. |
hippocampal delivery of neurotrophic factor-α1/carboxypeptidase e gene prevents neurodegeneration, amyloidosis, memory loss in alzheimer's disease male mice. |
2023-06-27 |
2023-08-14 |
mouse |
| Marcos Fabietti, Mufti Mahmud, Ahmad Lotfi, Alessandro Leparulo, Roberto Fontana, Stefano Vassanelli, Cristina Fasolat. Early Detection of Alzheimer's Disease from Cortical and Hippocampal Local Field Potentials using an Ensembled Machine Learning Model. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2023-06-22. PMID:37347628. |
early detection of alzheimer's disease from cortical and hippocampal local field potentials using an ensembled machine learning model. |
2023-06-22 |
2023-08-14 |
Not clear |
| Wen-Bin Zhang, Yue Huang, Xiao-Rou Guo, Meng-Qi Zhang, Xiang-Shan Yuan, Heng-Bing Z. DHCR24 reverses Alzheimer's disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice. Acta neuropathologica communications. vol 11. issue 1. 2023-06-21. PMID:37344916. |
dhcr24 reverses alzheimer's disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xfad mice. |
2023-06-21 |
2023-08-14 |
mouse |
| Anastasiya Rakovskaya, Margarita Chigriai, Ilya Bezprozvanny, Ekaterina Pchitskay. Expansion Microscopy Application for Calcium Protein Clustering Imaging in Cells and Brain Tissues. Current protocols. vol 3. issue 6. 2023-06-20. PMID:37338219. |
we compare ip3r clustering in the ca1 area of the hippocampus of wild-type and 5xfad alzheimer's disease model mice. |
2023-06-20 |
2023-08-14 |
mouse |
| T L Stephen, L Korobkova, B Breningstall, K Nguyen, S Mehta, M Pachicano, K T Jones, D Hawes, R P Cabeen, M S Bienkowsk. Machine Learning Classification of Alzheimer's Disease Pathology Reveals Diffuse Amyloid as a Major Predictor of Cognitive Impairment in Human Hippocampal Subregions. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333119. |
machine learning classification of alzheimer's disease pathology reveals diffuse amyloid as a major predictor of cognitive impairment in human hippocampal subregions. |
2023-06-19 |
2023-08-14 |
human |
| Sabrina Smith, Sarah C Hop. The 5XFAD mouse model of Alzheimer's disease displays age-dependent deficits in habituation to a novel environment. Aging brain. vol 3. 2023-06-19. PMID:37333676. |
habituation to a novel environment is dependent on hippocampal function, suggesting that habituation behavior may be a relevant readout for hippocampal-dependent memory deficits that are characteristic of alzheimer's disease (ad). |
2023-06-19 |
2023-08-14 |
mouse |
| E K Karsuntseva, A D Voronova, A V Chadin, V V Shishkina, G A Fursa, S S Andretsova, I V Reshetov, O V Stepanova, V P Chekhoni. Application of Behavioral Tests for Evaluation of an Experimental Model of Alzheimer's Disease in Female Rats. Bulletin of experimental biology and medicine. 2023-06-19. PMID:37336813. |
alzheimer's disease was modeled in female wistar rats aged 4 months by stereotaxic bilateral injection of a synthetic peptide β-amyloid (aβ1-42) into the hippocampus. |
2023-06-19 |
2023-08-14 |
rat |
| Billie J Matchett, Sarah J Lincoln, Matt Baker, Nikoleta Tamvaka, Sydney A Labuzan, Tiffany N Hicks Sirmans, Christina M Moloney, Jacqueline Helminger, Kelly M Hinkle, Janisse Cabrera-Rodriguez, Daniel P Wickland, Patrick W Johnson, Michael G Heckman, Joseph S Reddy, Steven G Younkin, Minerva M Carrasquillo, Ranjan Duara, Neill R Graff-Radford, Cyril Pottier, Nilüfer Ertekin-Taner, Owen A Ross, Rosa Rademakers, Dennis W Dickson, Melissa E Murra. The SERPINA5 coding variant E228Q does not contribute to clinicopathologic characteristics in Alzheimer's disease: A cross-sectional study. Medicine. vol 102. issue 24. 2023-06-16. PMID:37327267. |
we previously demonstrated that increased expression of the serpina5 gene is associated with hippocampal vulnerability in alzheimer's disease (ad) brains. |
2023-06-16 |
2023-08-14 |
Not clear |
| Gongpeng Cao, Manli Zhang, Yiping Wang, Jing Zhang, Ying Han, Xin Xu, Jinguo Huang, Guixia Kan. End-to-end automatic pathology localization for Alzheimer's disease diagnosis using structural MRI. Computers in biology and medicine. vol 163. 2023-06-15. PMID:37321102. |
several important brain regions, such as rostral hippocampus and globus pallidus, are identified to be highly associated with alzheimer's disease. |
2023-06-15 |
2023-08-14 |
Not clear |
| Elva Arulchelvan, Sven Vannest. Promising neurostimulation routes for targeting the hippocampus to improve episodic memory: A review. Brain research. 2023-06-14. PMID:37315722. |
importantly, these three functional mechanisms and the hippocampus' structural integrity are negatively impacted throughout the progression of alzheimer's disease, with episodic memory deficits likewise evident in early stages. |
2023-06-14 |
2023-08-14 |
human |
| Li-Zhe Liu, Shu-Juan Fan, Jun-Xia Gao, Wen-Bin Li, Xiao-Hui Xia. Ceftriaxone ameliorates hippocampal synapse loss by inhibiting microglial/macrophages activation in glial glutamate transporter-1 dependent manner in the APP/PS1 mouse model of Alzheimer's disease. Brain research bulletin. 2023-06-10. PMID:37301482. |
ceftriaxone ameliorates hippocampal synapse loss by inhibiting microglial/macrophages activation in glial glutamate transporter-1 dependent manner in the app/ps1 mouse model of alzheimer's disease. |
2023-06-10 |
2023-08-14 |
mouse |
| Anika Wuestefeld, Hannah Baumeister, Jenna N Adams, Robin de Flores, Carl Hodgetts, Negar Mazloum-Farzaghi, Rosanna K Olsen, Vyash Puliyadi, Tammy T Tran, Arnold Bakker, Kelsey L Canada, Marshall A Dalton, Ana M Daugherty, Renaud La Joie, Lei Wang, Madigan Bedard, Esther Buendia, Amanda Denning, David J Irwin, Ranjit Ittyerah, Edward B Lee, Sydney Lim, Maria Mercedes Iñiguez de Onzoño Martin, Monica Munoz Lopez, Theresa Schuck, Winifred Trotman, Alicia Vela, Paul Yushkevich, Katrin Amunts, Jean C Augustinack, Song-Lin Ding, Ricardo Insausti, Olga Kedo, David Berron, Laura E M Wiss. Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292729. |
the medial temporal lobe (mtl) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as alzheimer's disease neurofibrillary tau tangles. |
2023-06-09 |
2023-08-14 |
human |
| Sarah B Scheinman, Kuei Y Tseng, Simon Alford, Leon M Ta. Higher Neuronal Facilitation and Potentiation with APOE4 Suppressed by Angiotensin II. Research square. 2023-06-09. PMID:37292788. |
progressive hippocampal degeneration is a key component of alzheimer's disease (ad) progression. |
2023-06-09 |
2023-08-14 |
Not clear |
| Mohammad Golam Sabbir, Mamiko Swanson, Robert C Speth, Benedict C Albens. Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of respiratory chain-associated proteins, mitochondrial ultrastructure, and respiration: implications in Alzheimer's disease. Frontiers in cell and developmental biology. vol 11. 2023-06-09. PMID:37293125. |
hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of respiratory chain-associated proteins, mitochondrial ultrastructure, and respiration: implications in alzheimer's disease. |
2023-06-09 |
2023-08-14 |
mouse |
| . Erratum: Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens. Frontiers in neuroscience. vol 17. 2023-06-08. PMID:37287798. |
erratum: sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of alzheimer's disease and the potential role of local estrogens. |
2023-06-08 |
2023-08-14 |
mouse |
| Chiara Falcicchia, Francesca Tozzi, Martina Gabrielli, Stefano Amoretti, Greta Masini, Gabriele Nardi, Stefano Guglielmo, Gian Michele Ratto, Ottavio Arancio, Claudia Verderio, Nicola Origli. Microglial extracellular vesicles induce Alzheimer's disease-related cortico-hippocampal network dysfunction. Brain communications. vol 5. issue 3. 2023-06-08. PMID:37288314. |
here, using chronic eeg recordings, we show that a single injection of extracellular vesicles carrying β-amyloid into the mouse entorhinal cortex could trigger alterations in the cortical and hippocampal activity that are reminiscent of those found in alzheimer's disease mouse models and human patients. |
2023-06-08 |
2023-08-14 |
mouse |
| Elham Sajadi, Javad Sajedianfard, Saeid Hosseinzadeh, Mahnaz Taherianfar. Effect of insulin and cinnamon extract on spatial memory and gene expression of GLUT1, 3, and 4 in streptozotocin-induced Alzheimer's model in rats. Iranian journal of basic medical sciences. vol 26. issue 6. 2023-06-06. PMID:37275760. |
since diminished hippocampal insulin signaling leads to memory impairment, insulin resistance and hyperinsulinemia are probably associated with alzheimer's disease (ad). |
2023-06-06 |
2023-08-14 |
rat |
| ZiJie Liu, Qing Xia, Xue Zhao, FeiFei Zheng, JiaYing Xiao, FangLiang Ge, DaYong Wang, Xu Ga. The Landscape of m6A Regulators in Multiple Brain Regions of Alzheimer's Disease. Molecular neurobiology. 2023-06-05. PMID:37273154. |
our work evaluated the alteration profile of m6a regulators and their influences on alzheimer's disease in 4 brain regions: the postcentral gyrus, superior frontal gyrus, hippocampus, and entorhinal cortex. |
2023-06-05 |
2023-08-14 |
Not clear |
| Ruth S Nelson, Erin L Abner, Gregory A Jicha, Frederick A Schmitt, Jing Di, Donna M Wilcock, Justin M Barber, Linda J Van Eldik, Yuriko Katsumata, David W Fardo, Peter T Nelso. Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort. Acta neuropathologica communications. vol 11. issue 1. 2023-06-02. PMID:37269007. |
the npi-q and cdr ratings were correlated with neuropathology findings at autopsy: alzheimer's disease neuropathological changes (adnc), neocortical and amygdala-only lewy bodies (lbs), limbic predominant age-related tdp-43 encephalopathy neuropathologic changes (late-nc), primary age-related tauopathy (part), hippocampal sclerosis, and cerebrovascular pathologies. |
2023-06-02 |
2023-08-14 |
human |