| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Rylett, M J Ball, E H Colhou. Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6661641. |
evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with alzheimer's disease. |
1984-03-12 |
2023-08-12 |
human |
| R J Rylett, M J Ball, E H Colhou. Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6661641. |
hippocampal and neocortical cholinergic nerve cell endings, prepared as synaptosomes, from brains of patients with alzheimer's disease, also accumulated choline by a high-affinity mechanism; however, the velocity of uptake into both brain areas was decreased in comparison with controls. |
1984-03-12 |
2023-08-12 |
human |
| R J Rylett, M J Ball, E H Colhou. Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6661641. |
choline transport into synaptosomes from alzheimer frontal cortex was reduced approximately 50%, while uptake into alzheimer hippocampal synaptosomes represented only 20% of the control activity. |
1984-03-12 |
2023-08-12 |
human |
| H A Hartmann, S K White, R L Levin. Neuroaxonal dystrophy with neuromelanin deposition, neurofibrillary tangles, and neuronal loss. Light- and electron-microscopic changes in a 45-year-old woman with progressive psychomotor deterioration. Acta neuropathologica. vol 61. issue 3-4. 1984-01-27. PMID:6650130. |
neurofibrillary degeneration, senile plaques, and granulovacuolar degeneration in the hippocampus produced a picture of alzheimer's disease. |
1984-01-27 |
2023-08-12 |
Not clear |
| T D Bird, S Stranahan, S M Sumi, M Raskin. Alzheimer's disease: choline acetyltransferase activity in brain tissue from clinical and pathological subgroups. Annals of neurology. vol 14. issue 3. 1983-12-20. PMID:6227276. |
choline acetyltransferase activity was significantly lower in patients with early-onset alzheimer's disease than in age-matched control subjects in frontal cortex, temporal cortex, hippocampus, and cerebellum. |
1983-12-20 |
2023-08-12 |
human |
| T D Bird, S Stranahan, S M Sumi, M Raskin. Alzheimer's disease: choline acetyltransferase activity in brain tissue from clinical and pathological subgroups. Annals of neurology. vol 14. issue 3. 1983-12-20. PMID:6227276. |
in contrast, choline acetyltransferase activity in patients with late-onset alzheimer's disease was significantly lower than in age-matched control subjects only in hippocampus. |
1983-12-20 |
2023-08-12 |
human |
| G L Mancardi, B H Liwnicz, T I Mandybu. Fibrous astrocytes in Alzheimer's disease and senile dementia of Alzheimer's type. Acta neuropathologica. vol 61. issue 1. 1983-11-23. PMID:6353837. |
in four patients with alzheimer's disease (ad), on patient with senile dementia of alzheimer's type (sdat) and five age-matched controls, occipital cortex, frontal cortex, and hippocampus were evaluated for the distribution of fibrous astrocytes (fa), using peroxidase-anti-peroxidase for glial fibrillary acidic protein (gfap). |
1983-11-23 |
2023-08-12 |
Not clear |
| D M Mann, A M Tinkler, P O Yate. Neurological disease and herpes simplex virus. An immunohistochemical study. Acta neuropathologica. vol 60. issue 1-2. 1983-09-23. PMID:6308942. |
in the patient with alzheimer's disease va was present within nerve and glial cells of the amygdala, within oligodendrocytes of the optic and olfactory tracts and in macrophages within the temporal cortex hippocampus and cerebellum. |
1983-09-23 |
2023-08-12 |
Not clear |
| A Probst, V Basler, B Bron, J Ulric. Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region. Brain research. vol 268. issue 2. 1983-09-20. PMID:6191831. |
neuritic plaques in senile dementia of alzheimer type: a golgi analysis in the hippocampal region. |
1983-09-20 |
2023-08-12 |
Not clear |
| A Probst, V Basler, B Bron, J Ulric. Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region. Brain research. vol 268. issue 2. 1983-09-20. PMID:6191831. |
tissue sections from the hippocampal region of patients with senile dementia of alzheimer type were examined in 75-100 microns thick vibratome sections impregnated by the golgi-cox method and counterstained with cresyl violet. |
1983-09-20 |
2023-08-12 |
Not clear |
| A Nordberg, C Larsson, R Adolfsson, I Alafuzoff, B Winbla. Muscarinic receptor compensation in hippocampus of Alzheimer patients. Journal of neural transmission. vol 56. issue 1. 1983-07-15. PMID:6133910. |
muscarinic receptor compensation in hippocampus of alzheimer patients. |
1983-07-15 |
2023-08-12 |
Not clear |
| A Nordberg, C Larsson, R Adolfsson, I Alafuzoff, B Winbla. Muscarinic receptor compensation in hippocampus of Alzheimer patients. Journal of neural transmission. vol 56. issue 1. 1983-07-15. PMID:6133910. |
the activity of the acetylcholine synthesizing enzyme choline acetyltransferase (chat) (presynaptic marker) and number of muscarine-like receptor binding sites have been measured in the hippocampus from eight individuals with senile dementia of alzheimer type (sdat) and ten controls. |
1983-07-15 |
2023-08-12 |
Not clear |
| G K Wilcock, M M Esir. Plaques, tangles and dementia. A quantitative study. Journal of the neurological sciences. vol 56. issue 2-3. 1983-02-25. PMID:7175555. |
the temporal lobe cortex and hippocampus were the areas most severely affected by the increased neurofibrillary tangle formation in senile dementia due to alzheimer's disease. |
1983-02-25 |
2023-08-12 |
human |
| A Probst, J Ulrich, P U Heit. Senile dementia of Alzheimer type: astroglial reaction to extracellular neurofibrillary tangles in the hippocampus. An immunocytochemical and electron-microscopic study. Acta neuropathologica. vol 57. issue 1. 1982-08-07. PMID:7090745. |
senile dementia of alzheimer type: astroglial reaction to extracellular neurofibrillary tangles in the hippocampus. |
1982-08-07 |
2023-08-12 |
Not clear |
| A Probst, J Ulrich, P U Heit. Senile dementia of Alzheimer type: astroglial reaction to extracellular neurofibrillary tangles in the hippocampus. An immunocytochemical and electron-microscopic study. Acta neuropathologica. vol 57. issue 1. 1982-08-07. PMID:7090745. |
two types of alzheimer neurofibrillary tangles may be found in the hippocampus in senile dementia of the alzheimer type. |
1982-08-07 |
2023-08-12 |
Not clear |
| A Arregui, E K Perry, M Rossor, B E Tomlinso. Angiotensin converting enzyme in Alzheimer's disease increased activity in caudate nucleus and cortical areas. Journal of neurochemistry. vol 38. issue 5. 1982-05-27. PMID:6278093. |
enzyme activity was found to be elevated by 44% and 41% in the medial hippocampus and parahippocampal gyrus, respectively, and by 27% and 29% in the frontal cortex (area 10 of brodman) and caudate nucleus, respectively, in alzheimer's disease patients. |
1982-05-27 |
2023-08-12 |
Not clear |
| D Dahl, D J Selkoe, R T Pero, A Bignam. Immunostaining of neurofibrillary tangles in Alzheimer's senile dementia with a neurofilament antiserum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 1. 1982-03-22. PMID:7033478. |
using anti-chicken brain neurofilament antisera, alzheimer's neurofibrillary tangles from two patients with senile dementia were stained by immunofluorescence and by the peroxidase-antiperoxidase procedure in cryostat sections of hippocampus and frontal cortex. |
1982-03-22 |
2023-08-12 |
cattle |
| S H Appe. A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer disease. Annals of neurology. vol 10. issue 6. 1982-03-13. PMID:6173010. |
in alzheimer disease, the abnormalities would lie in failure of the hippocampus and cortical cells to supply the relevant cholinergic neurotrophic hormone with resulting impairment of medial septal and nucleus basalis neurons. |
1982-03-13 |
2023-08-12 |
Not clear |
| M A Bell, M J Bal. Morphometric comparison of hippocampal microvasculature in ageing and demented people: diameters and densities. Acta neuropathologica. vol 53. issue 4. 1981-06-13. PMID:7223373. |
the diameters and densities of capillaries and arterioles in the hippocampal cortex of normal subjects and patients with alzheimer's dementia were measured in thick celloidin sections stained for alkaline phosphatase. |
1981-06-13 |
2023-08-12 |
human |
| M A Bell, M J Bal. Morphometric comparison of hippocampal microvasculature in ageing and demented people: diameters and densities. Acta neuropathologica. vol 53. issue 4. 1981-06-13. PMID:7223373. |
regional changes may, however, be important: those hippocampal zones showing the greatest severity of or increment in nerve cell lesions do correspond to those having the highest levels of or increase in capillary density and the greatest decrease in diameter, suggesting a direct association between neuronal susceptibility to alzheimer changes and degree of regional blood supply. |
1981-06-13 |
2023-08-12 |
human |