| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Yu, Yang Gao, Bengt Winblad, Lars O Tjernberg, Sophia Schedin-Weis. A Super-Resolved View of the Alzheimer's Disease-Related Amyloidogenic Pathway in Hippocampal Neurons. Journal of Alzheimer's disease : JAD. vol 83. issue 2. 2021-11-18. PMID:34366358. |
a super-resolved view of the alzheimer's disease-related amyloidogenic pathway in hippocampal neurons. |
2021-11-18 |
2023-08-13 |
Not clear |
| Nan Li, Na Li, Fenghua Xu, Ming Yu, Zichen Qiao, Yu Zho. Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding. Molecular brain. vol 14. issue 1. 2021-11-18. PMID:34641940. |
studies have demonstrated the critical role of hippocampal ghrelin/ghs-r1a signaling in synaptic physiology, memory and cognitive dysfunction associated with alzheimer's disease (ad). |
2021-11-18 |
2023-08-13 |
Not clear |
| Kewei Chen, Xiaojuan Guo, Rong Pan, Chengjie Xiong, Danielle J Harvey, Yinghua Chen, Li Yao, Yi Su, Eric M Reima. Limitations of clinical trial sample size estimate by subtraction of two measurements. Statistics in medicine. 2021-11-18. PMID:34725853. |
the mri-based hippocampal volume measurements from the alzheimer's disease neuroimaging initiative (adni) and monte carlo simulations (mcs) were used to illustrate the existing bias and variability of estimates. |
2021-11-18 |
2023-08-13 |
human |
| Christine W Fung, Jia Guo, Hongjun Fu, Helen Y Figueroa, Elisa E Konofagou, Karen E Duf. Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy. Science advances. vol 6. issue 42. 2021-11-17. PMID:33067235. |
tau pathology in alzheimer's disease (ad) first develops in the entorhinal cortex (ec), then spreads to the hippocampus, followed by the neocortex. |
2021-11-17 |
2023-08-13 |
mouse |
| Juan Francisco Flores-Vázquez, Gabriel Ramírez-García, Oscar René Marrufo-Meléndez, Ruth Alcalá-Lozano, Morten Peter Lietz, Yaneth Rodríguez-Agudelo, Gilberto Isaac Acosta-Castillo, Remco J Renken, Andre Aleman, Stefanie Enriquez-Geppert, Ana Luisa Sosa-Orti. Anosognosia in Amnestic Mild Cognitive Impairment Is Related to Diminished Hippocampal Volume Comparable to Alzheimer's Disease Dementia: Preliminary MRI Findings. Frontiers in aging neuroscience. vol 13. 2021-11-17. PMID:34776927. |
anosognosia in amnestic mild cognitive impairment is related to diminished hippocampal volume comparable to alzheimer's disease dementia: preliminary mri findings. |
2021-11-17 |
2023-08-13 |
human |
| Yuanyuan Wei, Nianwei Huang, Yong Liu, Xi Zhang, Silun Wang, Xiaoying Tan. Hippocampal and Amygdalar Morphological Abnormalities in Alzheimer's Disease Based on Three Chinese MRI Datasets. Current Alzheimer research. vol 17. issue 13. 2021-11-16. PMID:33602087. |
hippocampal and amygdalar morphological abnormalities in alzheimer's disease based on three chinese mri datasets. |
2021-11-16 |
2023-08-13 |
Not clear |
| Dasfne Lee-Liu, Christian Gonzalez-Billaul. Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on https://doi.org/10.1111/jnc.15323. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:33909918. |
neuron-intrinsic origin of hyperexcitability during early pathogenesis of alzheimer's disease: an editorial highlight for "hippocampal hyperactivity in a rat model of alzheimer's disease" on https://doi.org/10.1111/jnc.15323. |
2021-11-16 |
2023-08-13 |
mouse |
| Dasfne Lee-Liu, Christian Gonzalez-Billaul. Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on https://doi.org/10.1111/jnc.15323. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:33909918. |
in alzheimer's disease (ad), hippocampal hyperactivation is already present at early stages of the disorder, in some cases, even when the individual is still asymptomatic. |
2021-11-16 |
2023-08-13 |
mouse |
| Andrew E Weller, Glenn A Doyle, Benjamin C Reiner, Richard C Crist, Wade H Berrettin. Analysis of differential gene expression and transcript usage in hippocampus of Apoe null mutant mice: Implications for Alzheimer's disease. Neuroscience research. 2021-11-16. PMID:34757086. |
analysis of differential gene expression and transcript usage in hippocampus of apoe null mutant mice: implications for alzheimer's disease. |
2021-11-16 |
2023-08-13 |
mouse |
| Nasrin Hashemi-Firouzi, Siamak Shahidi, Sara Soleimani As. Chronic stimulation of the serotonergic 5-HT4 receptor modulates amyloid-beta-related impairments in synaptic plasticity and memory deficits in male rats. Brain research. vol 1773. 2021-11-12. PMID:34695393. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by memory decline and impaired hippocampal synaptic plasticity. |
2021-11-12 |
2023-08-13 |
rat |
| Emily J Van Etten, Pradyumna K Bharadwaj, Georg A Hishaw, Matthew J Huentelman, Theodore P Trouard, Matthew D Grilli, Gene E Alexande. Influence of regional white matter hyperintensity volume and apolipoprotein E ε4 status on hippocampal volume in healthy older adults. Hippocampus. vol 31. issue 5. 2021-11-11. PMID:33586848. |
our findings indicate that in cognitively healthy older adults, elevated wmh volume regionally localized to the temporal lobes in apoe ε4 carriers is associated with reduced hippocampal volume, suggesting greater vulnerability to brain aging and the risk for alzheimer's disease. |
2021-11-11 |
2023-08-13 |
Not clear |
| Grant C Hayward, Daniela Caceres, Emily N Copeland, Bradley J Baranowski, Ahmad Mohammad, Kennedy C Whitley, Val A Fajardo, Rebecca E K MacPherso. Characterization of Alzheimer's disease-like neuropathology in Duchenne's muscular dystrophy using the DBA/2J mdx mouse model. FEBS open bio. 2021-11-11. PMID:34668666. |
biochemical analyses of the d2 mdx brain revealed higher soluble amyloid precursor protein β (appβ) and app in the prefrontal cortex of mdx mice compared with wt, and lower soluble appα in the hippocampus, suggestive of a shift towards amyloidogenesis and a similar pathogenesis to alzheimer's disease. |
2021-11-11 |
2023-08-13 |
mouse |
| Davis C Woodworth, Hannah L Nguyen, Zainab Khan, Claudia H Kawas, María M Corrada, S Ahmad Sajjad. Utility of MRI in the identification of hippocampal sclerosis of aging. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 5. 2021-11-10. PMID:33615673. |
hippocampal sclerosis of aging (hs) is a common pathology often misdiagnosed as alzheimer's disease. |
2021-11-10 |
2023-08-13 |
human |
| Davis C Woodworth, Hannah L Nguyen, Zainab Khan, Claudia H Kawas, María M Corrada, S Ahmad Sajjad. Utility of MRI in the identification of hippocampal sclerosis of aging. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 5. 2021-11-10. PMID:33615673. |
we tested the hypothesis that participants with hs would have a magnetic resonance imaging (mri)-detectable hippocampal pattern of atrophy distinct from participants without hs, both with and without alzheimer's disease neuropathology (adnp). |
2021-11-10 |
2023-08-13 |
human |
| Nabila E Abdelmeguid, Mahmoud I M Khalil, Rasha Elhabet, Ahmed S Sultan, Sherine Abdel Sala. Combination of docosahexaenoic acid and Ginko biloba extract improves cognitive function and hippocampal tissue damages in a mouse model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 116. 2021-11-10. PMID:34182090. |
combination of docosahexaenoic acid and ginko biloba extract improves cognitive function and hippocampal tissue damages in a mouse model of alzheimer's disease. |
2021-11-10 |
2023-08-13 |
mouse |
| Yingjie Qi, Igor Klyubin, Tomas Ondrejcak, Neng-Wei Hu, Michael J Rowa. Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer's disease amyloidosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 12. 2021-11-10. PMID:34188184. |
because the presence and extent of cortisol excess in prodromal alzheimer's disease predicts the onset of cognitive symptoms we hypothesised that corticosteroids would exacerbate the inhibition of hippocampal synaptic long-term potentiation in a rat model of alzheimer's disease amyloidosis. |
2021-11-10 |
2023-08-13 |
rat |
| Mark R Libowitz, Ke Wei, Thao Tran, Karen Chu, Kristina Moncrieffe, Michael G Harrington, Kevin Kin. Regional brain volumes relate to Alzheimer's disease cerebrospinal fluid biomarkers and neuropsychometry: A cross-sectional, observational study. PloS one. vol 16. issue 7. 2021-11-10. PMID:34292973. |
113 participants ranging from cognitively healthy to alzheimer's disease underwent mri exams to obtain measurements of hippocampus, prefrontal cortex, precuneus, parietal cortex, and occipital lobe volumes. |
2021-11-10 |
2023-08-13 |
human |
| Mark R Libowitz, Ke Wei, Thao Tran, Karen Chu, Kristina Moncrieffe, Michael G Harrington, Kevin Kin. Regional brain volumes relate to Alzheimer's disease cerebrospinal fluid biomarkers and neuropsychometry: A cross-sectional, observational study. PloS one. vol 16. issue 7. 2021-11-10. PMID:34292973. |
lastly, impaired cognitive status (mild cognitive impairment and alzheimer's disease) was optimally predicted in a selective regression model by a worse performance on the stroop interference test (p < 0.001), a worse performance on the boston naming test (p < 0.001), along with lower prefrontal cortex volume (p = 0.002) and lower hippocampus volume (p = 0.007). |
2021-11-10 |
2023-08-13 |
human |
| Ming-Wan Su, Jing-Nian Ni, Tian-Yu Cao, Shuo-Shi Wang, Jing Shi, Jin-Zhou Tia. The Correlation Between Olfactory Test and Hippocampal Volume in Alzheimer's Disease and Mild Cognitive Impairment Patients: A Meta-Analysis. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744696. |
the correlation between olfactory test and hippocampal volume in alzheimer's disease and mild cognitive impairment patients: a meta-analysis. |
2021-11-10 |
2023-08-13 |
Not clear |
| Ryan J Bevan, Tim R Hughes, Pete A Williams, Mark A Good, B Paul Morgan, James E Morga. Retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental Alzheimer's disease. Acta neuropathologica communications. vol 8. issue 1. 2021-11-09. PMID:33287900. |
retinal ganglion cell degeneration correlates with hippocampal spine loss in experimental alzheimer's disease. |
2021-11-09 |
2023-08-13 |
mouse |