| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G M Anderso. Monoamines in autism: an update of neurochemical research on a pervasive developmental disorder. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:3309489. |
studies on the possible causes of the increased platelet 5ht in autism suggest that an alteration in platelet physiology is the cause of the increase. |
1987-11-19 |
2023-08-11 |
human |
| R B Minderaa, G M Anderson, F R Volkmar, G W Akkerhuis, D J Cohe. Urinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects. Biological psychiatry. vol 22. issue 8. 1987-09-11. PMID:2440483. |
the relevance of these findings to the possibility that increased gut production of 5-ht might cause the elevated whole blood 5-ht levels seen in autism is discussed. |
1987-09-11 |
2023-08-11 |
human |
| S Kuperman, J Beeghly, T Burns, L Tsa. Association of serotonin concentration to behavior and IQ in autistic children. Journal of autism and developmental disorders. vol 17. issue 1. 1987-06-16. PMID:3571137. |
twenty-five boys meeting dsm-iii criteria for infantile autism were evaluated for iq, age, and behavior score on the autism behavior checklist (abc), in order to determine the ability to predic platelet-rich plasma (prp) serotonin concentrations. |
1987-06-16 |
2023-08-11 |
Not clear |
| S Kuperman, J Beeghly, T Burns, L Tsa. Association of serotonin concentration to behavior and IQ in autistic children. Journal of autism and developmental disorders. vol 17. issue 1. 1987-06-16. PMID:3571137. |
individuals with all of these items appear to be more severely affected with the disorder of autism and have a tendency to higher adjusted prp serotonin concentration. |
1987-06-16 |
2023-08-11 |
Not clear |
| Y Hoshino, T Yamamoto, M Kaneko, H Kumashir. Plasma free tryptophan concentration in autistic children. Brain & development. vol 8. issue 4. 1987-02-05. PMID:3799912. |
the plasma free and total tryptophan (trp) and blood serotonin levels in autistic children were examined simultaneously in order to establish a relationship between these parameters and the pathophysiology of infantile autism. |
1987-02-05 |
2023-08-11 |
human |
| R de Villard, E Flachaire, J M Thoulon, J Dalery, J Maillet, C Chauvin, C Quincy, B Renau. [Platelet serotonin concentrations in autistic children and members of their families]. L'Encephale. vol 12. issue 4. 1987-02-02. PMID:3792272. |
children with early infantile autism have often high platelet serotonin (5 ht) levels. |
1987-02-02 |
2023-08-11 |
Not clear |
| T Katsui, M Okuda, S Usuda, T Koizum. Kinetics of 3H-serotonin uptake by platelets in infantile autism and developmental language disorder (including five pairs of twins). Journal of autism and developmental disorders. vol 16. issue 1. 1986-04-30. PMID:3957859. |
the kinetics of 5-ht uptake by platelets was studied in cases of infantile autism and developmental language disorder (dld) and normal subjects. |
1986-04-30 |
2023-08-11 |
human |
| C Dreux, J M Launa. [Blood platelets: neuronal model in psychiatric disorders]. L'Encephale. vol 11. issue 2. 1985-09-06. PMID:2862006. |
for example: serotonin uptake, bioamine storage, enzymatic activities are modified in different types of depression and schizophrenia, infantile autism, neurologic diseases (migraine, chorea, down syndrom). |
1985-09-06 |
2023-08-11 |
Not clear |
| E R Ritvo, B J Freeman, A Yuwiler, E Geller, A Yokota, P Schroth, P Nova. Study of fenfluramine in outpatients with the syndrome of autism. The Journal of pediatrics. vol 105. issue 5. 1984-12-27. PMID:6502317. |
fenfluramine was administered to 14 outpatient children with the syndrome of autism to determine whether previously produced decreases in blood serotonin concentrations and clinical improvements could be reinstituted. |
1984-12-27 |
2023-08-12 |
Not clear |
| R S Root-Bernstein, F C Westal. Fenfluramine binds 5-hydroxytryptophan. Brain research bulletin. vol 12. issue 1. 1984-06-01. PMID:6201240. |
fenfluramine, an anorexigenic drug, lowers serotonin (5-hydroxytryptamine) and 5-hydroxyindoleacetic acid levels in brain, spinal fluid, and blood, and has been used as a treatment for autism. |
1984-06-01 |
2023-08-12 |
Not clear |
| G M Anderson, R B Minderaa, P P van Benthem, F R Volkmar, D J Cohe. Platelet imipramine binding in autistic subjects. Psychiatry research. vol 11. issue 2. 1984-05-24. PMID:6584936. |
previous reports of elevated platelet serotonin (5-ht) concentrations in autistic subjects suggest that platelet 5-ht uptake might be altered in autism. |
1984-05-24 |
2023-08-12 |
human |
| G M Anderson, R B Minderaa, P P van Benthem, F R Volkmar, D J Cohe. Platelet imipramine binding in autistic subjects. Psychiatry research. vol 11. issue 2. 1984-05-24. PMID:6584936. |
the normal number (bmax) and affinity (kd) of the imi binding site in autistic subjects suggest that the regulation of 5-ht uptake is not different in autism. |
1984-05-24 |
2023-08-12 |
human |
| L A Bulakhova, L S Usherenk. [Biogenic amine metabolism in patients with oligophrenia of different origins]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 83. issue 10. 1984-02-14. PMID:6229120. |
the levels of blood serotonin and the urinary concentrations of 5-hiaa, dopa, dopamine, adrenaline as well as the products of their conversion and disintegration were assessed in 104 oligophrenic patients of different age with different genesis (phenylketonurea, down's disease, mental retardation of residual organic origin including the complicated syndrome of early childhood autism). |
1984-02-14 |
2023-08-12 |
Not clear |
| F C Westall, R S Root-Bernstei. Suggested connection between autism, serotonin, and myelin basic protein. The American journal of psychiatry. vol 140. issue 9. 1983-10-08. PMID:6193716. |
suggested connection between autism, serotonin, and myelin basic protein. |
1983-10-08 |
2023-08-12 |
Not clear |
| J G Young, M E Kavanagh, G M Anderson, B A Shaywitz, D J Cohe. Clinical neurochemistry of autism and associated disorders. Journal of autism and developmental disorders. vol 12. issue 2. 1983-02-25. PMID:6184361. |
the fundamental preclinical and clinical studies of serotonin, dopamine, and norepinephrine metabolism related to infantile autism are reviewed, and new studies are suggested as examples of the productive strategies that will illuminate features of the autistic syndrome in the next decade. |
1983-02-25 |
2023-08-12 |
Not clear |
| P Kamoun, O Doua. [Serotonin and autism]. Annales de biologie clinique. vol 38. issue 4. 1981-02-24. PMID:6160783. |
[serotonin and autism]. |
1981-02-24 |
2023-08-12 |
Not clear |
| O Douay, P Debray Ritzen, P Kamou. [Blood serotonin and tryptophan in autism]. Annales de biologie clinique. vol 38. issue 4. 1981-02-24. PMID:7446877. |
[blood serotonin and tryptophan in autism]. |
1981-02-24 |
2023-08-12 |
Not clear |
| Serotonin, platelets, and autism. British medical journal. vol 1. issue 6128. 1978-09-01. PMID:656860. |
serotonin, platelets, and autism. |
1978-09-01 |
2023-08-11 |
Not clear |
| Y Hoshino, H Kumashiro, M Kaneko, Y Takahash. The effects of methylphenidate on early infantile autism and its relation to serum serotonin levels. Folia psychiatrica et neurologica japonica. vol 31. issue 4. 1978-05-08. PMID:608662. |
the effects of methylphenidate on early infantile autism and its relation to serum serotonin levels. |
1978-05-08 |
2023-08-11 |
Not clear |
| D V Siva Sanka. Uptake of 5-hydroxytryptamine by isolated platelets in childhood schizophrenia and autism. Neuropsychobiology. vol 3. issue 4. 1978-02-18. PMID:593539. |
uptake of 5-hydroxytryptamine by isolated platelets in childhood schizophrenia and autism. |
1978-02-18 |
2023-08-11 |
Not clear |