| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E H Rickards, M Prendergas. Fluoxetine and serotonin in autism. The American journal of psychiatry. vol 149. issue 6. 1992-06-25. PMID:1590516. |
fluoxetine and serotonin in autism. |
1992-06-25 |
2023-08-11 |
Not clear |
| R De Villard, E Flachaire, A Laujin, J Maillet, O Revol, S Charles, J C Mamelle, B Renaud, C Quinc. [Platelet serotonin concentration in children under 5 years of age]. Pediatrie. vol 46. issue 12. 1992-05-21. PMID:1667036. |
high platelet serotonin concentrations have been reported in children with early infantile autism. |
1992-05-21 |
2023-08-11 |
Not clear |
| R De Villard, E Flachaire, A Laujin, J Maillet, O Revol, S Charles, J C Mamelle, B Renaud, C Quinc. [Platelet serotonin concentration in children under 5 years of age]. Pediatrie. vol 46. issue 12. 1992-05-21. PMID:1667036. |
there therefore appears to be a physiological elevation of platelet serotonin concentration in infants and young children, and this has to be taken into consideration in the interpretation of the elevated values found in cases of infantile autism. |
1992-05-21 |
2023-08-11 |
Not clear |
| C T Gordon, J L Rapoport, S D Hamburger, R C State, G B Mannhei. Differential response of seven subjects with autistic disorder to clomipramine and desipramine. The American journal of psychiatry. vol 149. issue 3. 1992-03-24. PMID:1536276. |
clomipramine, a serotonin reuptake blocker that has unique antiobsessional properties, was hypothesized to have a different effect from that of desipramine, a tricyclic antidepressant with selective adrenergic effects, for the stereotyped, repetitive behaviors in autism. |
1992-03-24 |
2023-08-11 |
human |
| V K Singh, R P Warren, E A Sing. Binding of [3H]serotonin to lymphocytes in patients with neuropsychiatric disorders. Molecular and chemical neuropathology. vol 13. issue 3. 1991-08-15. PMID:2099781. |
based on recent studies of neuroimmune networks, the lymphocyte binding of serotonin neurotransmitter was studied in patients with alzheimer's disease, idiopathic mental retardation, and autism. |
1991-08-15 |
2023-08-11 |
Not clear |
| J Piven, G C Tsai, E Nehme, J T Coyle, G A Chase, S E Folstei. Platelet serotonin, a possible marker for familial autism. Journal of autism and developmental disorders. vol 21. issue 1. 1991-07-03. PMID:2037549. |
platelet serotonin, a possible marker for familial autism. |
1991-07-03 |
2023-08-11 |
human |
| J Piven, G C Tsai, E Nehme, J T Coyle, G A Chase, S E Folstei. Platelet serotonin, a possible marker for familial autism. Journal of autism and developmental disorders. vol 21. issue 1. 1991-07-03. PMID:2037549. |
serotonin (5ht) levels in platelet-rich plasma were measured in 5 autistic subjects who had siblings with either autism or pervasive developmental disorder (pdd), 23 autistic subjects without affected siblings, and 10 normal controls. |
1991-07-03 |
2023-08-11 |
human |
| J Piven, G C Tsai, E Nehme, J T Coyle, G A Chase, S E Folstei. Platelet serotonin, a possible marker for familial autism. Journal of autism and developmental disorders. vol 21. issue 1. 1991-07-03. PMID:2037549. |
these results suggest that 5ht level in autistic subjects may be associated with genetic liability to autism. |
1991-07-03 |
2023-08-11 |
human |
| R S Root-Bernstein, F C Westal. Serotonin binding sites. II. Muramyl dipeptide binds to serotonin binding sites on myelin basic protein, LHRH, and MSH-ACTH 4-10. Brain research bulletin. vol 25. issue 6. 1991-04-01. PMID:1705162. |
application of such a mechanism for induction of autoimmunity may be of importance in understanding a number of postinfectious and postvaccinal neuropathies, and suggests a possible etiology for autism, in which many patients have high blood serotonin levels, autoimmune reactions to myelin basic protein, and antibodies to serotonin binding sites. |
1991-04-01 |
2023-08-11 |
Not clear |
| R S Chamberlain, B H Herma. A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. Biological psychiatry. vol 28. issue 9. 1991-01-28. PMID:2175218. |
a novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. |
1991-01-28 |
2023-08-11 |
Not clear |
| R S Chamberlain, B H Herma. A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. Biological psychiatry. vol 28. issue 9. 1991-01-28. PMID:2175218. |
a novel biochemical model for autism is presented, which proposes that a subgroup of autistic individuals may have a hypersecretion of pineal melatonin that produces a cascade of biochemical effects including a corresponding hyposecretion of pituitary proopiomelanocortin (pomc) peptides and a hypersecretion of hypothalamic opioid peptides and serotonin (5-ht). |
1991-01-28 |
2023-08-11 |
Not clear |
| R S Chamberlain, B H Herma. A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. Biological psychiatry. vol 28. issue 9. 1991-01-28. PMID:2175218. |
therefore, autism may reflect a dysfunction in the pineal-hypothalamic-pituitary-adrenal axis which, modulates pomc and 5-ht systems of the brain. |
1991-01-28 |
2023-08-11 |
Not clear |
| R S Chamberlain, B H Herma. A novel biochemical model linking dysfunctions in brain melatonin, proopiomelanocortin peptides, and serotonin in autism. Biological psychiatry. vol 28. issue 9. 1991-01-28. PMID:2175218. |
this model is consistent with numerous clinical investigations implicating hypersecretion of brain 5-ht and opioid peptides in autism. |
1991-01-28 |
2023-08-11 |
Not clear |
| R K Abramson, H H Wright, R Carpenter, W Brennan, O Lumpuy, E Cole, S R Youn. Elevated blood serotonin in autistic probands and their first-degree relatives. Journal of autism and developmental disorders. vol 19. issue 3. 1989-11-01. PMID:2793785. |
whole blood serotonin levels and platelet counts were studied in 14 families, representing 57 family members and 15 probands who met dsm iii criteria for infantile autism. |
1989-11-01 |
2023-08-11 |
Not clear |
| R B Minderaa, G M Anderson, F R Volkmar, D Harcherick, G W Akkerhuis, D J Cohe. Whole blood serotonin and tryptophan in autism: temporal stability and the effects of medication. Journal of autism and developmental disorders. vol 19. issue 1. 1989-06-01. PMID:2708296. |
whole blood serotonin and tryptophan in autism: temporal stability and the effects of medication. |
1989-06-01 |
2023-08-11 |
human |
| D L Ross, W M Klykylo, R Hitzeman. Reduction of elevated CSF beta-endorphin by fenfluramine in infantile autism. Pediatric neurology. vol 3. issue 2. 1989-06-01. PMID:2977280. |
fenfluramine therapy has been reported to improve behavior in infantile autism and has been associated with a decrease in abnormally increased blood serotonin content. |
1989-06-01 |
2023-08-11 |
Not clear |
| J M Launay, P Ferrari, M Haimart, C Bursztejn, F Tabuteau, A Braconnier, D Pasques-Bondoux, C Luong, C Dreu. Serotonin metabolism and other biochemical parameters in infantile autism. A controlled study of 22 autistic children. Neuropsychobiology. vol 20. issue 1. 1989-04-14. PMID:2466221. |
serotonin metabolism and other biochemical parameters in infantile autism. |
1989-04-14 |
2023-08-11 |
Not clear |
| J M Launay, P Ferrari, M Haimart, C Bursztejn, F Tabuteau, A Braconnier, D Pasques-Bondoux, C Luong, C Dreu. Serotonin metabolism and other biochemical parameters in infantile autism. A controlled study of 22 autistic children. Neuropsychobiology. vol 20. issue 1. 1989-04-14. PMID:2466221. |
based on data including urinary serotonin and 5-hydroxyindoleacetic acid, platelet serotonin uptake and efflux, platelet monoamine oxidase and glutathione peroxidase activities, and uric acid and plasma tryptophan, the origin(s) of such hyperserotonemia in autism appear(s) to be of metabolic origin, i.e., a decreased catabolism and/or an increased biosynthesis of serotonin. |
1989-04-14 |
2023-08-11 |
Not clear |
| C Bursztejn, P Ferrari, C Dreux, A Braconnier, S Lancreno. [Metabolism of serotonin in autism in children]. L'Encephale. vol 14. issue 6. 1989-04-11. PMID:3068046. |
[metabolism of serotonin in autism in children]. |
1989-04-11 |
2023-08-11 |
Not clear |
| G M Anderso. Monoamines in autism: an update of neurochemical research on a pervasive developmental disorder. Medical biology. vol 65. issue 2-3. 1987-11-19. PMID:3309489. |
recent neurochemical studies of norepinephrine (ne), dopamine (da), and serotonin (5ht) in autism are reviewed. |
1987-11-19 |
2023-08-11 |
human |