| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Th Postert, J Eyding, D Berg, H Przuntek, G Becker, M Finger, L Schöl. Transcranial sonography in spinocerebellar ataxia type 3. Journal of neural transmission. Supplementum. issue 68. 2004-10-05. PMID:15354398. |
aim of the present study was to evaluate the diagnostic potential of tcs in spinocerebellar ataxia type 3 (sca3), a neurodegenerative disease affecting the cerebellum, multiple pontine nuclei, substantia nigra, pallidum, putamen, caudate nucleus and long spinal tracts. |
2004-10-05 |
2023-08-12 |
Not clear |
| O Rolón Lacarriere, A Rasmussen Almaraz, H Hernández Cruz, J Carranza del Río, M González Cruz, J Gutiérrez Moctezum. [Spinocerebellar ataxia type 7: clinical and molecular genetic analysis of a Mexican family]. Revista de neurologia. vol 38. issue 8. 2004-07-23. PMID:15122543. |
spinocerebellar ataxias (sca) constitute a group of neurodegenerative diseases characterized by cerebellar disfunction alone or associated with other neurological anomalies. |
2004-07-23 |
2023-08-12 |
Not clear |
| Hélio A Ghizoni Teive, Walter Oleschko Arrud. [The Drew family of Walworth: one century from the first evaluation until the final diagnosis, Machado-Joseph disease]. Arquivos de neuro-psiquiatria. vol 62. issue 1. 2004-07-15. PMID:15122458. |
autosomal dominant spinocerebellar ataxia (sca) is an heterogeneous group of neurodegenerative diseases involving cerebellum and its connections. |
2004-07-15 |
2023-08-12 |
Not clear |
| Alfredo Brusco, Cinzia Gellera, Claudia Cagnoli, Alessandro Saluto, Alessia Castucci, Chiara Michielotto, Vincenza Fetoni, Caterina Mariotti, Nicola Migone, Stefano Di Donato, Franco Taron. Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families. Archives of neurology. vol 61. issue 5. 2004-06-17. PMID:15148151. |
autosomal dominant cerebellar ataxias are a clinical and genetically heterogeneous group of progressive neurodegenerative diseases, at present associated with 22 loci (spinocerebellar ataxia [sca] 1-sca8, sca10-sca19, sca21, sca22, fibroblast growth factor 14 [fgf14]-sca, and dentatorubral-pallidoluysian atrophy [drpla]). |
2004-06-17 |
2023-08-12 |
Not clear |
| K Kirchhof, A N Apostolidis, C J Mathias, C J Fowle. Erectile and urinary dysfunction may be the presenting features in patients with multiple system atrophy: a retrospective study. International journal of impotence research. vol 15. issue 4. 2003-10-23. PMID:12934060. |
multiple system atrophy (msa) is a progressive neurodegenerative disease characterized by parkinsonism and cerebellar, autonomic, urinary, and/or pyramidal dysfunction. |
2003-10-23 |
2023-08-12 |
Not clear |
| R John Maye. From neurodegeneration to neurohomeostasis: the role of ubiquitin. Drug news & perspectives. vol 16. issue 2. 2003-10-14. PMID:12792671. |
several years ago ubiquitin immunocytochemistry first demonstrated that ubiquitin protein conjugates are present in intraneuronal inclusions in all the major human chronic neurodegenerative diseases, as well as in inclusions in cerebellar astrocytomas and in hepatocytes in alcoholic liver disease. |
2003-10-14 |
2023-08-12 |
human |
| Juan Fernandez-Ruiz, Rosalinda Díaz, Cynthia Hall-Haro, Patricia Vergara, Aldo Fiorentini, Lilia Nuñez, René Drucker-Colín, Adriana Ochoa, Petra Yescas, Astrid Rasmussen, Maria-Elisa Alons. Olfactory dysfunction in hereditary ataxia and basal ganglia disorders. Neuroreport. vol 14. issue 10. 2003-09-26. PMID:12876469. |
first, an olfactory dysfunction has been found in different neurodegenerative diseases, and second, human functional imaging has shown cerebellar activation during olfaction. |
2003-09-26 |
2023-08-12 |
human |
| Karsten Schmidt, Stefan Kins, Andreas Schild, Roger M Nitsch, Brian A Hemmings, Jürgen Göt. Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. The European journal of neuroscience. vol 16. issue 11. 2003-03-25. PMID:12473071. |
pr55/balpha and bbeta protein expression varies significantly in areas of the brain affected by neurodegenerative diseases such as the hippocampus or cerebellum. |
2003-03-25 |
2023-08-12 |
human |
| J H Anderson, M C Yavuz, B M Kazar, P Christova, C M Gome. The vestibulo-ocular reflex and velocity storage in spinocerebellar ataxia 8. Archives italiennes de biologie. vol 140. issue 4. 2003-01-22. PMID:12228985. |
the autosomal dominant spinocerebellar ataxias (scas) are a group of neurodegenerative diseases characterized by progressive instability of posture and gait, incoordination, ocular motor dysfunction, and dysarthria due to degeneration of cerebellar and brainstem neurons. |
2003-01-22 |
2023-08-12 |
Not clear |
| Elan D Louis, Dikoma C Shungu, Steven Chan, Xiangling Mao, Eva C Jurewicz, Dryden Watne. Metabolic abnormality in the cerebellum in patients with essential tremor: a proton magnetic resonance spectroscopic imaging study. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401550. |
the reduction in cerebellar cortical naa/tcr indicates that there is neuronal damage or loss in et, suggesting that et may be a neurodegenerative disease. |
2002-12-26 |
2023-08-12 |
Not clear |
| C Colosimo, F R Pezzell. The symptomatic treatment of multiple system atrophy. European journal of neurology. vol 9. issue 3. 2002-07-08. PMID:11985626. |
multiple system atrophy (msa) is a neurodegenerative disease of undetermined aetiology that occurs sporadically and manifests itself as a combination of parkinsonian, autonomic, cerebellar and pyramidal signs. |
2002-07-08 |
2023-08-12 |
Not clear |
| Joanna T Pang, Paola Giunti, Susan Chamberlain, Shu F An, Roberta Vitaliani, Tomaso Scaravilli, Lillian Martinian, Nicholas W Wood, Francesco Scaravilli, Olaf Ansorg. Neuronal intranuclear inclusions in SCA2: a genetic, morphological and immunohistochemical study of two cases. Brain : a journal of neurology. vol 125. issue Pt 3. 2002-05-03. PMID:11872620. |
spinocerebellar ataxia 2 (sca2) belongs to the family of autosomal dominant cerebellar ataxias (adca), a genetically heterogeneous group of neurodegenerative diseases. |
2002-05-03 |
2023-08-12 |
Not clear |
| R Ceravolo, B Fattori, A Nuti, G Dell'Agnello, G Cei, A Casani, A Nacci, L Murri, U Bonuccell. Contribution of cerebellum and brainstem in the control of eye movement: evidence from a functional study in a clinical model. Acta neurologica Scandinavica. vol 105. issue 1. 2002-05-03. PMID:11903106. |
the idiopathic cerebellar ataxias (idca) comprise a wide spectrum of neurodegenerative diseases with heterogeneous neuropathology, characterized by the negativity of search for any known genetic mutation. |
2002-05-03 |
2023-08-12 |
human |
| P M Geomini, P L Dellemijn, G L Breme. Paraneoplastic cerebellar degeneration: neurological symptoms pointing to occult ovarian cancer. Gynecologic and obstetric investigation. vol 52. issue 2. 2001-12-04. PMID:11586046. |
paraneoplastic cerebellar degeneration with anti-yo antibodies is a rare but disabling neurodegenerative disease that may point to an occult ovarian cancer. |
2001-12-04 |
2023-08-12 |
Not clear |
| S S Ingrand, A Wahl, S Favrelière, F Barbot, C Tallinea. Quantification of long-chain aldehydes by gas chromatography coupled to mass spectrometry as a tool for simultaneous measurement of plasmalogens and their aldehydic breakdown products. Analytical biochemistry. vol 280. issue 1. 2000-06-30. PMID:10805522. |
two of these are affected in neurodegenerative diseases (cerebral cortex and hippocampus) and one is rich in white matter (cerebellum). |
2000-06-30 |
2023-08-12 |
rat |
| D W Dickson, W Lin, W K Liu, S H Ye. Multiple system atrophy: a sporadic synucleinopathy. Brain pathology (Zurich, Switzerland). vol 9. issue 4. 1999-11-16. PMID:10517510. |
multiple system atrophy (msa) is a sporadic neurodegenerative disease characterized clinically by varying degrees of parkinsonism, cerebellar ataxia and autonomic dysfunction and pathologically by degeneration in the substantia nigra, putamen, olivary nucleus, pontine nuclei and cerebellum. |
1999-11-16 |
2023-08-12 |
Not clear |
| G Y Ching, C L Chien, R Flores, R K Lie. Overexpression of alpha-internexin causes abnormal neurofilamentous accumulations and motor coordination deficits in transgenic mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 8. 1999-04-27. PMID:10191315. |
these torpedoes are abnormal swellings of purkinje cell axons that are usually seen in neurodegenerative diseases involving the cerebellum. |
1999-04-27 |
2023-08-12 |
mouse |
| J A Heckroth, N J Hobart, D Summer. Transplanted neurons alter the course of neurodegenerative disease in Lurcher mutant mice. Experimental neurology. vol 154. issue 2. 1999-02-04. PMID:9878172. |
the unilateral rescue of lurcher inferior olivary neurons in cerebellar transplant hosts indicates that transplanted neurons may interact with diseased host neural circuits to reduce transneuronal degeneration in the course of a neurodegenerative disease. |
1999-02-04 |
2023-08-12 |
mouse |
| H Hashida, J Goto, N Zhao, N Takahashi, M Hirai, I Kanazawa, Y Sakak. Cloning and mapping of ZNF231, a novel brain-specific gene encoding neuronal double zinc finger protein whose expression is enhanced in a neurodegenerative disorder, multiple system atrophy (MSA). Genomics. vol 54. issue 1. 1999-01-07. PMID:9806829. |
msa is a sporadic progressive neurodegenerative disease characterized clinically by cerebellar symptoms, parkinsonism, autonomic dysfunction, or their various combinations, but its pathogenesis has yet to be clarified. |
1999-01-07 |
2023-08-12 |
Not clear |
| Y Hayashi, A Kakita, M Yamada, S Egawa, S Oyanagi, H Naito, S Tsuji, H Takahash. Hereditary dentatorubral-pallidoluysian atrophy: ubiquitinated filamentous inclusions in the cerebellar dentate nucleus neurons. Acta neuropathologica. vol 95. issue 5. 1998-07-13. PMID:9600594. |
we examined the cerebellar dentate nucleus (cdn) in 16 patients with hereditary dentatorubral-pallidoluysian atrophy (drpla), one of the neurodegenerative diseases caused by expansion of a cag repeat encoding a polyglutamine tract in the disease protein. |
1998-07-13 |
2023-08-12 |
Not clear |