| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Satoru Ota, Kuniaki Tsuchiya, Midori Anno, Kazuhiro Niizato, Haruhiko Akiyam. Distribution of cerebello-olivary degeneration in idiopathic late cortical cerebellar atrophy: clinicopathological study of four autopsy cases. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 28. issue 1. 2008-05-21. PMID:18181834. |
late cortical cerebellar atrophy (lcca) is a neurodegenerative disease which presents with slowly progressive cerebellar ataxia as a prominent symptom and is characterized neuropathologically by a limited main lesion to the cerebellar cortex and inferior olivary nucleus. |
2008-05-21 |
2023-08-12 |
Not clear |
| Naoya Egami, Aki Inoue, Ryuichi Osanai, Nobuo Kitahara, Kimitaka Kag. Vocal cord abductor paralysis in multiple system atrophy: a case report. Acta oto-laryngologica. Supplementum. issue 559. 2008-04-29. PMID:18340590. |
multiple system atrophy (msa) is a progressive neurodegenerative disease that is characterized by varying degrees of parkinsonism and cerebellar, corticospinal, and autonomic dysfunction. |
2008-04-29 |
2023-08-12 |
Not clear |
| A G Papatsoris, S Papapetropoulos, C Singer, C Delivelioti. Urinary and erectile dysfunction in multiple system atrophy (MSA). Neurourology and urodynamics. vol 27. issue 1. 2008-02-28. PMID:17563111. |
multiple system atrophy (msa) is a neurodegenerative disease of undetermined etiology that occurs sporadically and manifests itself as a combination of parkinsonian, autonomic, cerebellar, and pyramidal signs. |
2008-02-28 |
2023-08-12 |
Not clear |
| C Kieling, P R Prestes, M L Saraiva-Pereira, L B Jardi. Survival estimates for patients with Machado-Joseph disease (SCA3). Clinical genetics. vol 72. issue 6. 2008-01-22. PMID:17894834. |
machado-joseph disease (mjd), one of the most prevalent autosomal dominant cerebellar ataxias, is a neurodegenerative disease that starts during adulthood, with patients showing difficulties in gait, later becoming bedridden, and ultimately presenting premature death. |
2008-01-22 |
2023-08-12 |
Not clear |
| Eniko Sáfrány, László Balikó, András Guseo, Bernadett Faragó, Béla Meleg. [The autosomal dominant cerebellar ataxias are hereditary neurodegenerative diseases]. Orvosi hetilap. vol 148. issue 45. 2007-12-27. PMID:17984023. |
[the autosomal dominant cerebellar ataxias are hereditary neurodegenerative diseases]. |
2007-12-27 |
2023-08-12 |
Not clear |
| Wolfgang M Schmidt, Cornelia Kraus, Harald Höger, Sonja Hochmeister, Felicitas Oberndorfer, Manuela Branka, Sonja Bingemann, Hans Lassmann, Markus Müller, Lúcia Inês Macedo-Souza, Mariz Vainzof, Mayana Zatz, André Reis, Reginald E Bittne. Mutation in the Scyl1 gene encoding amino-terminal kinase-like protein causes a recessive form of spinocerebellar neurodegeneration. EMBO reports. vol 8. issue 7. 2007-10-23. PMID:17571074. |
we show that the pathology of mdf comprises cerebellar atrophy, purkinje cell loss and optic nerve atrophy, and therefore defines a new animal model for neurodegenerative diseases with cerebellar involvement in humans. |
2007-10-23 |
2023-08-12 |
mouse |
| M Minnerop, K Specht, J Ruhlmann, N Schimke, M Abele, A Weyer, U Wüllner, T Klockgethe. Voxel-based morphometry and voxel-based relaxometry in multiple system atrophy-a comparison between clinical subtypes and correlations with clinical parameters. NeuroImage. vol 36. issue 4. 2007-10-18. PMID:17512219. |
multiple system atrophy (msa) is a neurodegenerative disease affecting basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord. |
2007-10-18 |
2023-08-12 |
Not clear |
| Elisabeth Olstad, Hong Qu, Ursula Sonnewal. Long-term kainic acid exposure reveals compartmentation of glutamate and glutamine metabolism in cultured cerebellar neurons. Neurochemistry international. vol 50. issue 7-8. 2007-09-18. PMID:17196710. |
glutamate neurotoxicity is implicated in most neurodegenerative diseases, and in the present study the long-term effects of the glutamate agonist kainic acid (ka) on cerebellar neurons are investigated. |
2007-09-18 |
2023-08-12 |
Not clear |
| Ellika Schalling, Britta Hammarberg, Lena Harteliu. Perceptual and acoustic analysis of speech in individuals with spinocerebellar ataxia (SCA). Logopedics, phoniatrics, vocology. vol 32. issue 1. 2007-07-16. PMID:17454658. |
with current progress in genetic research, autosomal, dominant, hereditary, neurodegenerative diseases, affecting the cerebellum and cerebellar connections, are increasingly diagnosed as spinocerebellar ataxias (sca). |
2007-07-16 |
2023-08-12 |
human |
| Naima Bouslam, Ahmed Bouhouche, Ali Benomar, Sylvain Hanein, Stephan Klebe, Hamid Azzedine, Silvia Di Giandomenico, Anne Boland-Augé, Filippo M Santorelli, Alexandra Durr, Alexis Brice, Mohamed Yahyaoui, Giovanni Stevani. A novel locus for autosomal recessive spastic ataxia on chromosome 17p. Human genetics. vol 121. issue 3-4. 2007-07-10. PMID:17273843. |
autosomal recessive spastic ataxias are a heterogeneous group of neurodegenerative diseases usually characterized by the early onset of cerebellar and pyramidal signs. |
2007-07-10 |
2023-08-12 |
Not clear |
| Haiyan Chen, Erika S Piedras-Renterí. Altered frequency-dependent inactivation and steady-state inactivation of polyglutamine-expanded alpha1A in SCA6. American journal of physiology. Cell physiology. vol 292. issue 3. 2007-04-24. PMID:17020933. |
spinocerebellar ataxia type 6 (sca6) is a neurodegenerative disease of the cerebellum and inferior olives characterized by a late-onset cerebellar ataxia and selective loss of purkinje neurons. |
2007-04-24 |
2023-08-12 |
human |
| S Joshua Langmade, Sarah E Gale, Andrey Frolov, Ikuko Mohri, Kinuko Suzuki, Synthia H Mellon, Steven U Walkley, Douglas F Covey, Jean E Schaffer, Daniel S Or. Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 37. 2006-10-30. PMID:16940355. |
niemann-pick type c1 (npc1) disease is a fatal neurodegenerative disease characterized by neuronal lipid storage and progressive purkinje cell loss in the cerebellum. |
2006-10-30 |
2023-08-12 |
mouse |
| C Colosimo, D Tiple, G K Wennin. Management of multiple system atrophy: state of the art. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 12. 2006-10-12. PMID:16284911. |
multiple system atrophy (msa) is a sporadic neurodegenerative disease of undetermined aetiology presenting with parkinsonian, autonomic, cerebellar, and pyramidal signs. |
2006-10-12 |
2023-08-12 |
Not clear |
| Antoni Matilla Dueñas, Robert Goold, Paola Giunt. Molecular pathogenesis of spinocerebellar ataxias. Brain : a journal of neurology. vol 129. issue Pt 6. 2006-06-19. PMID:16613893. |
the autosomal dominant spinocerebellar ataxias (scas) are a group of neurodegenerative diseases, clinically and genetically heterogeneous, characterized by loss of balance and motor coordination due to dysfunction of the cerebellum and its afferent and efferent connections. |
2006-06-19 |
2023-08-12 |
Not clear |
| M Tsirigotis, M Y Tang, M Beyers, M Zhang, J Woulfe, D A Gra. Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin. Neuropathology and applied neurobiology. vol 32. issue 1. 2006-03-14. PMID:16409551. |
spinocerebellar ataxia type 1 (sca1) is an incurable neurodegenerative disease resulting from loss of purkinje neurones within the cerebellum. |
2006-03-14 |
2023-08-12 |
mouse |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. A role for both wild-type and expanded ataxin-7 in transcriptional regulation. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:15936949. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the brainstem, retina and purkinje cells of the cerebellum. |
2006-03-09 |
2023-08-12 |
Not clear |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. Identification and characterization of Spinocerebellar Ataxia Type 7 (SCA7) isoform SCA7b in mice. Biochimica et biophysica acta. vol 1731. issue 3. 2006-02-03. PMID:16297465. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the cerebellum, brainstem and retina. |
2006-02-03 |
2023-08-12 |
mouse |
| F J Fernandez-Gomez, M Gomez-Lazaro, D Pastor, S Calvo, N Aguirre, M F Galindo, J Jordá. Minocycline fails to protect cerebellar granular cell cultures against malonate-induced cell death. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242643. |
these results suggest that the minocycline protection observed in several neurodegenerative disease models is selective, since it is absent from cultured cerebellar granular cells challenged with malonate. |
2006-01-23 |
2023-08-12 |
rat |
| D C Paviour, S L Price, J M Stevens, A J Lees, N C Fo. Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy. Neurology. vol 64. issue 4. 2005-10-18. PMID:15728291. |
postmortem studies have shown atrophy of the superior cerebellar peduncle (scp) to distinguish progressive supranuclear palsy (psp) from other neurodegenerative diseases. |
2005-10-18 |
2023-08-12 |
Not clear |
| Meral Topçu, Omer Faruk Aydin, Cengiz Yalçinkaya, Göknur Haliloğlu, Sabiha Aysun, Banu Anlar, Haluk Topaloğlu, Güzide Turanli, Dilek Yalnizoğlu, Mehmet Kesimer, Turgay Coşku. L-2-hydroxyglutaric aciduria: a report of 29 patients. The Turkish journal of pediatrics. vol 47. issue 1. 2005-06-29. PMID:15884621. |
l-2-hydroxyglutaric aciduria (l2hga) is a chronic slowly progressive neurodegenerative disease characterized mainly by psychomotor developmental delay and cerebellar dysfunction. |
2005-06-29 |
2023-08-12 |
Not clear |