| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan Wu, Xu Wang, Xiaohan Li, Huidi Teng, Tao Tian, Jing Ba. Spinocerebellar ataxia type 23 (SCA23): a review. Journal of neurology. vol 268. issue 12. 2021-11-04. PMID:33175256. |
spinocerebellar ataxias (scas), formerly known as autosomal dominant cerebellar ataxias (adcas), are a group of hereditary heterogeneous neurodegenerative diseases. |
2021-11-04 |
2023-08-13 |
Not clear |
| Matthew R Burns, Nikolaus R McFarlan. Current Management and Emerging Therapies in Multiple System Atrophy. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 17. issue 4. 2021-10-28. PMID:32767032. |
multiple system atrophy (msa) is a progressive neurodegenerative disease variably associated with motor, nonmotor, and autonomic symptoms, resulting from putaminal and cerebellar degeneration and associated with glial cytoplasmic inclusions enriched with α-synuclein in oligodendrocytes and neurons. |
2021-10-28 |
2023-08-13 |
Not clear |
| Louisa P Selvadurai, Nellie Georgiou-Karistianis, Rosita Shishegar, Cathlin Sheridan, Gary F Egan, Martin B Delatycki, Ian H Harding, Louise A Corbe. Longitudinal structural brain changes in Friedreich ataxia depend on disease severity: the IMAGE-FRDA study. Journal of neurology. vol 268. issue 11. 2021-10-13. PMID:33860369. |
friedreich ataxia is an inherited neurodegenerative disease, with cerebral and cerebellar pathology evident. |
2021-10-13 |
2023-08-13 |
Not clear |
| Anton N Shuvaev, Olga S Belozor, Oleg Mozhei, Dariya A Yakovleva, Ilya V Potapenko, Andrey N Shuvaev, Marina V Smolnikova, Vladimir V Salmin, Alla B Salmina, Hirokazu Hirai, Anja G Teschemacher, Sergey Kasparo. Chronic optogenetic stimulation of Bergman glia leads to dysfunction of EAAT1 and Purkinje cell death, mimicking the events caused by expression of pathogenic ataxin-1. Neurobiology of disease. vol 154. 2021-09-02. PMID:33753288. |
multiple lines of evidence suggest that in cerebellar neurodegenerative diseases reactive bg has a negative impact on neuronal function and survival through compromised eaat activity. |
2021-09-02 |
2023-08-13 |
mouse |
| Sayed Ausim Aziz. Role of the cerebellum in the phenotype of neurodegenerative diseases: Mitigate or exacerbate? Neuroscience letters. vol 760. 2021-08-17. PMID:34246702. |
role of the cerebellum in the phenotype of neurodegenerative diseases: mitigate or exacerbate? |
2021-08-17 |
2023-08-13 |
Not clear |
| Mohamed A Elsaey, Kazuhiko Namikawa, Reinhard W Köste. Genetic Modeling of the Neurodegenerative Disease Spinocerebellar Ataxia Type 1 in Zebrafish. International journal of molecular sciences. vol 22. issue 14. 2021-08-17. PMID:34298970. |
dominant spinocerebellar ataxias (scas) are progredient neurodegenerative diseases commonly affecting the survival of purkinje cells (pcs) in the human cerebellum. |
2021-08-17 |
2023-08-13 |
human |
| Milvia Alata, Arturo González-Vega, Valeria Piazza, Anke Kleinert-Altamirano, Carmen Cortes, Juan C Ahumada-Juárez, Jose R Eguibar, Alejandra López-Juárez, Victor H Hernande. Longitudinal Evaluation of Cerebellar Signs of H-ABC Tubulinopathy in a Patient and in the Frontiers in neurology. vol 12. 2021-08-03. PMID:34335454. |
longitudinal evaluation of cerebellar signs of h-abc tubulinopathy in a patient and in the hypomyelination with atrophy of the basal ganglia and cerebellum (h-abc) is a central neurodegenerative disease due to mutations in the tubulin beta-4a (tubb4a) gene, characterized by motor development delay, abnormal movements, ataxia, spasticity, dysarthria, and cognitive deficits. |
2021-08-03 |
2023-08-13 |
Not clear |
| Alejandra Lopez-Juarez, Arturo Gonzalez-Vega, Anke Kleinert-Altamirano, Valeria Piazza, Angeles Garduno-Robles, Milvia Alata, Carlos Villaseñor-Mora, Jose R Eguibar, Carmen Cortes, Luis Carlos Padierna, Victor H Hernande. Auditory impairment in H-ABC tubulinopathy. The Journal of comparative neurology. vol 529. issue 5. 2021-08-02. PMID:32681585. |
hypomyelination with atrophy of the basal ganglia and cerebellum (h-abc) is a neurodegenerative disease due to mutations in tubb4a. |
2021-08-02 |
2023-08-13 |
rat |
| Philip W Tipton, Dale C Ekbom, Amy L Rutt, Jay A van Gerpe. Vocal Fold "Paralysis": An Early Sign in Multiple System Atrophy. Journal of voice : official journal of the Voice Foundation. vol 34. issue 6. 2021-07-28. PMID:31324432. |
multiple system atrophy (msa) is a neurodegenerative disease characterized by a cerebellar syndrome, autonomic dysfunction, and extrapyramidal signs. |
2021-07-28 |
2023-08-13 |
Not clear |
| Daneck Lang-Ouellette, Kim M Gruver, Amy Smith-Dijak, François G C Blot, Chloe A Stewart, Pauline de Vanssay de Blavous, Connie H Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L Faust, Martijn Schonewille, Alanna J Wat. Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function. Nature communications. vol 12. issue 1. 2021-07-26. PMID:34226561. |
axonal swellings have been found on purkinje cell axons in the cerebellum both in healthy development and in neurodegenerative diseases, and computational models predicts that axonal swellings impair axonal function. |
2021-07-26 |
2023-08-13 |
mouse |
| Samira Ezi, Mahdi Eskandarian Boroujeni, Aysan Khatmi, Kimia Vakili, Mobina Fathi, Mohammad-Amin Abdollahifar, Fakhroddin Aghajanpour, Reza Soltani, Seyed Hamidreza Mirbehbahani, Fariba Khodagholi, Abbas Aliaghaei, Reza Mastery Farahan. Chronic Exposure to Tramadol Induces Neurodegeneration in the Cerebellum of Adult Male Rats. Neurotoxicity research. vol 39. issue 4. 2021-07-13. PMID:33818692. |
we also identified several signaling cascades chiefly related to neurodegenerative disease and energy metabolism that considerably deregulated in the cerebellum of tramadol-treated rats. |
2021-07-13 |
2023-08-13 |
rat |
| Walker S McKinney, James Bartolotti, Pravin Khemani, Jun Yi Wang, Randi J Hagerman, Matthew W Moscon. Cerebellar-cortical function and connectivity during sensorimotor behavior in aging FMR1 gene premutation carriers. NeuroImage. Clinical. vol 27. 2021-06-25. PMID:32711390. |
premutation carriers of the fmr1 gene are at risk of developing fragile x-associated tremor/ataxia syndrome (fxtas), a neurodegenerative disease characterized by motor, cognitive, and psychiatric decline as well as cerebellar and cerebral white matter pathology. |
2021-06-25 |
2023-08-13 |
Not clear |
| Taro Ishiguro, Yoshitaka Nagai, Kinya Ishikaw. Insight Into Spinocerebellar Ataxia Type 31 (SCA31) From Frontiers in neuroscience. vol 15. 2021-06-12. PMID:34113230. |
insight into spinocerebellar ataxia type 31 (sca31) from spinocerebellar ataxia type 31 (sca31) is a progressive neurodegenerative disease characterized by degeneration of purkinje cells in the cerebellum. |
2021-06-12 |
2023-08-13 |
Not clear |
| Bijia Song, Junchao Zh. Cerebellar malfunction and postoperative sleep disturbances after general anesthesia: a narrative review. Sleep & breathing = Schlaf & Atmung. 2021-05-15. PMID:33990908. |
future large-scale multicenter trials are needed to objectively support the present results, identify the initial cerebellar dysfunction to prevent postoperative sleep disturbances, and develop new therapeutic measures targeting sleep disturbances with possible far-reaching implications for neurodegenerative diseases in general. |
2021-05-15 |
2023-08-13 |
Not clear |
| Essa Alharby, Mona Obaid, Mohammed A O Elamin, Makki Almuntashri, Ismail Bakhsh, Manar Samman, Roy W A Peake, Ali Alasmari, Naif A M Almontashir. Progressive Ataxia and Neurologic Regression in Neurology. Genetics. vol 7. issue 3. 2021-04-16. PMID:33855173. |
progressive ataxia and neurologic regression in to identify the genetic cause of a late-onset immunodeficiency and subacute progressive neurodegenerative disease affecting cognition, motor, visual, and cerebellar systems in a patient with a family history of 2 younger siblings with an early-onset immunodeficiency disease. |
2021-04-16 |
2023-08-13 |
Not clear |
| Katharine J Liang, Erik S Carlso. Resistance, vulnerability and resilience: A review of the cognitive cerebellum in aging and neurodegenerative diseases. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30630042. |
resistance, vulnerability and resilience: a review of the cognitive cerebellum in aging and neurodegenerative diseases. |
2021-04-12 |
2023-08-13 |
Not clear |
| Katharine J Liang, Erik S Carlso. Resistance, vulnerability and resilience: A review of the cognitive cerebellum in aging and neurodegenerative diseases. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30630042. |
understanding the role of the cognitive cerebellum in neurodegenerative diseases has the potential to offer insight into origins of cognitive deficits in other neuropsychiatric disorders, which are often underappreciated, poorly understood, and not often treated. |
2021-04-12 |
2023-08-13 |
Not clear |
| Zhuoqing Chang, Ziyu Chen, Christopher D Stephen, Jeremy D Schmahmann, Hau-Tieng Wu, Guillermo Sapiro, Anoopum S Gupt. Accurate detection of cerebellar smooth pursuit eye movement abnormalities via mobile phone video and machine learning. Scientific reports. vol 10. issue 1. 2021-03-29. PMID:33122811. |
eye movements are disrupted in many neurodegenerative diseases and are frequent and early features in conditions affecting the cerebellum. |
2021-03-29 |
2023-08-13 |
human |
| Ivana Jedlickova, Anna Pristoupilova, Helena Hulkova, Alena Vrbacka, Viktor Stranecky, Eva Hruba, Pavel Jesina, Tomas Honzik, Ivan Hrdlicka, Jiri Fremuth, Kristyna Pivovarcikova, Ibrahim Bitar, Radoslav Matej, Stanislav Kmoch, Jakub Sikor. NOTCH2NLC CGG Repeats Are Not Expanded and Skin Biopsy Was Negative in an Infantile Patient With Neuronal Intranuclear Inclusion Disease. Journal of neuropathology and experimental neurology. vol 79. issue 10. 2021-03-01. PMID:32827029. |
we present a 7-year-old male patient with severe progressive neurodegenerative disease that included cerebellar symptoms with cerebellar atrophy on brain mri, psychomotor developmental regression, pseudobulbar syndrome, and polyneuropathy. |
2021-03-01 |
2023-08-13 |
Not clear |
| Michael Weng Lok Phang, Sze Yuen Lew, Ivy Chung, William Kiong-Seng Lim, Lee Wei Lim, Kah Hui Won. Therapeutic roles of natural remedies in combating hereditary ataxia: A systematic review. Chinese medicine. vol 16. issue 1. 2021-01-31. PMID:33509239. |
hereditary ataxia (ha) represents a group of genetically heterogeneous neurodegenerative diseases caused by dysfunction of the cerebellum or disruption of the connection between the cerebellum and other areas of the central nervous system. |
2021-01-31 |
2023-08-13 |
Not clear |