| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pierre-Marie Roger, Jean-Philippe Breittmayer, Jacques Durant, Frédéric Sanderson, Carole Ceppi, Christelle Brignone, Eric Cua, Philippe Clevenbergh, Jean-Gabriel Fuzibet, Alain Pesce, Alain Bernard, Pierre Dellamonic. Early CD4(+) T cell recovery in human immunodeficiency virus-infected patients receiving effective therapy is related to a down-regulation of apoptosis and not to proliferation. The Journal of infectious diseases. vol 185. issue 4. 2002-03-15. PMID:11865398. |
early cd4(+) t cell recovery in human immunodeficiency virus-infected patients receiving effective therapy is related to a down-regulation of apoptosis and not to proliferation. |
2002-03-15 |
2023-08-12 |
human |
| Pierre-Marie Roger, Jean-Philippe Breittmayer, Jacques Durant, Frédéric Sanderson, Carole Ceppi, Christelle Brignone, Eric Cua, Philippe Clevenbergh, Jean-Gabriel Fuzibet, Alain Pesce, Alain Bernard, Pierre Dellamonic. Early CD4(+) T cell recovery in human immunodeficiency virus-infected patients receiving effective therapy is related to a down-regulation of apoptosis and not to proliferation. The Journal of infectious diseases. vol 185. issue 4. 2002-03-15. PMID:11865398. |
this prospective study investigated the contributions of apoptosis and proliferation of cd4(+) t cells obtained by the introduction of a new antiretroviral treatment for human immunodeficiency virus infection. |
2002-03-15 |
2023-08-12 |
human |
| Pierre-Marie Roger, Jean-Philippe Breittmayer, Jacques Durant, Frédéric Sanderson, Carole Ceppi, Christelle Brignone, Eric Cua, Philippe Clevenbergh, Jean-Gabriel Fuzibet, Alain Pesce, Alain Bernard, Pierre Dellamonic. Early CD4(+) T cell recovery in human immunodeficiency virus-infected patients receiving effective therapy is related to a down-regulation of apoptosis and not to proliferation. The Journal of infectious diseases. vol 185. issue 4. 2002-03-15. PMID:11865398. |
sixty-nine patients completed the protocol, 22 of whom met our definition of a satisfactory immune reconstitution, showing a significantly more pronounced reduction in spontaneous cd4(+) t cell apoptosis at month 1 as well as month 3, compared with the other patients. |
2002-03-15 |
2023-08-12 |
human |
| Pierre-Marie Roger, Jean-Philippe Breittmayer, Jacques Durant, Frédéric Sanderson, Carole Ceppi, Christelle Brignone, Eric Cua, Philippe Clevenbergh, Jean-Gabriel Fuzibet, Alain Pesce, Alain Bernard, Pierre Dellamonic. Early CD4(+) T cell recovery in human immunodeficiency virus-infected patients receiving effective therapy is related to a down-regulation of apoptosis and not to proliferation. The Journal of infectious diseases. vol 185. issue 4. 2002-03-15. PMID:11865398. |
down-regulation of cd4(+) t cell apoptosis by antiretroviral treatment is the main mechanism associated with early cd4(+) t cell increase. |
2002-03-15 |
2023-08-12 |
human |
| J E Talmadge, R Singh, A Ageitos, S Buyukberbe. Potential for cytokine and product manipulation to improve the results of autologous stem cell transplantation for rheumatoid arthritis. The Journal of rheumatology. Supplement. vol 64. 2002-03-13. PMID:11642502. |
resulting in apoptosis, preferential deletion of cd4+ t cells, an inversion in the cd4:cd8 ratio, and depressed t cell function. |
2002-03-13 |
2023-08-12 |
Not clear |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
fas ligand-expressing b-1a lymphocytes mediate cd4(+)-t-cell apoptosis during schistosomal infection: induction by interleukin 4 (il-4) and il-10. |
2002-02-21 |
2023-08-12 |
mouse |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
a previous study of the murine model of schistosoma mansoni infection has implicated splenic cd19(+) b lymphocytes as fas ligand (fasl)-bearing mediators of cd4(+) t-lymphocyte apoptosis. |
2002-02-21 |
2023-08-12 |
mouse |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
the present study shows that b-cell deficiency leads to decreased cd4(+) t-cell apoptosis during infection and compares fasl expression and killer function of b-1a- and cd5(-) b-lymphocyte subsets. |
2002-02-21 |
2023-08-12 |
mouse |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
purified b-1a cells from uninfected mice were potent effectors of cd4(+) t-cell apoptosis, and the killing effect was enhanced during schistosome infection. |
2002-02-21 |
2023-08-12 |
mouse |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
these results suggest that fasl-expressing, splenic b-1a cells are important mediators of sea-stimulated cd4(+)-t-cell apoptosis and that maximal fasl expression on b-1a cells is dependent on antigenic stimulation and the presence of il-4 and il-10. |
2002-02-21 |
2023-08-12 |
mouse |
| J F Jacysyn, M Conde-Moscatelli, C R C Barrichello, U R Silva, M S Macedo, G P Amarante-Mende. Thymic epithelial cells mediate a Bcl-2-independent protection of single-positive thymocytes from dexamethasone-induced apoptosis. Experimental cell research. vol 272. issue 2. 2002-02-14. PMID:11777336. |
the protection conferred by 2bh4 cells, or by a primary culture of thymic stromal cells, is specific for the cd4(+)cd8(-) and cd4(-)cd8(+) single-positive thymocytes, whereas the broad-spectrum caspase inhibitor z-vad-fmk blocks apoptosis induced by dexamethasone in all thymocyte subpopulations. |
2002-02-14 |
2023-08-12 |
Not clear |
| Liqiang Wang, Patrick A Adegboyeg. Down-regulation of Fas expression in the lymph nodes of patients infected with human immunodeficiency virus. Archives of pathology & laboratory medicine. vol 126. issue 1. 2002-02-12. PMID:11800643. |
the mechanism by which human immunodeficiency virus 1 (hiv-1) infection causes increased rates of apoptosis and gradual chronic depletion of cd4(+) t lymphocytes in patients infected with hiv-1 is not known. |
2002-02-12 |
2023-08-12 |
human |
| R C Wilkins, D Wilkinson, H P Maharaj, P V Bellier, M B Cybulski, J R N McLea. Differential apoptotic response to ionizing radiation in subpopulations of human white blood cells. Mutation research. vol 513. issue 1-2. 2002-02-07. PMID:11719087. |
by generating dose response curves for cd4(+) and cd8(+) t-cells, the sensitivity of the mnca for detecting apoptosis in these two cell types was also examined. |
2002-02-07 |
2023-08-12 |
human |
| E A Dearstyne, N I Kerkvlie. Mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced decrease in anti-CD3-activated CD4(+) T cells: the roles of apoptosis, Fas, and TNF. Toxicology. vol 170. issue 1-2. 2002-01-31. PMID:11750091. |
mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd)-induced decrease in anti-cd3-activated cd4(+) t cells: the roles of apoptosis, fas, and tnf. |
2002-01-31 |
2023-08-12 |
mouse |
| F Petit, J Corbeil, J D Lelièvre, L Moutouh-de Parseval, G Pinon, D R Green, J C Ameisen, J Estaquie. Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells. European journal of immunology. vol 31. issue 12. 2002-01-24. PMID:11745371. |
while stimulation by anti-cd3 antibodies in solution induced cd4 t cell apoptosis both in the absence or presence of anti-cd95 antibodies, stimulation by immobilized anti-cd3 antibodies rendered cd4(+) t cells resistant to cd95-mediated death and led to increased cd4 t cell proliferation in response to cd95 ligation. |
2002-01-24 |
2023-08-12 |
Not clear |
| F Petit, J Corbeil, J D Lelièvre, L Moutouh-de Parseval, G Pinon, D R Green, J C Ameisen, J Estaquie. Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells. European journal of immunology. vol 31. issue 12. 2002-01-24. PMID:11745371. |
our findings suggest a novel mechanism whereby in addition to its role in inducing t cell apoptosis, cd95 signaling during hiv infection may also provide a costimulatory signal leading to an enhancement of cd4 t cell proliferation in response to cd3-tcr complex engagement. |
2002-01-24 |
2023-08-12 |
Not clear |
| H P Carroll, S Ali, J A Kirb. Accelerating the induction of Fas-mediated T cell apoptosis: a strategy for transplant tolerance? Clinical and experimental immunology. vol 126. issue 3. 2002-01-23. PMID:11737081. |
it was found that cd4 cross-linking potently induced apoptosis, even in the absence of fas stimulation. |
2002-01-23 |
2023-08-12 |
Not clear |
| Z Szondy, R Tóth, E Szegezdi, U Reichert, P Ancian, L Fésü. Cell death in HIV pathogenesis and its modulation by retinoids. Annals of the New York Academy of Sciences. vol 946. 2002-01-22. PMID:11762998. |
although cd4 t cell production is impaired in patients infected with hiv, there is now increasing evidence that the primary basis of t cell depletion is accelerated apoptosis of cd4 and cd8 t cells. |
2002-01-22 |
2023-08-12 |
human |
| Z Szondy, R Tóth, E Szegezdi, U Reichert, P Ancian, L Fésü. Cell death in HIV pathogenesis and its modulation by retinoids. Annals of the New York Academy of Sciences. vol 946. 2002-01-22. PMID:11762998. |
in this paper the potential effects of retinoids on cd4 t cell apoptosis is discussed. |
2002-01-22 |
2023-08-12 |
human |
| M M Odinak, G N Bisaga, N M kalinina, S B Akimov, N I Davydov. [Immunogenetic cytokine restriction in multiple sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 101. issue 9. 2002-01-14. PMID:11586702. |
lymphocyte subpopulations were investigated using monoclonal antibodies (moscow) to the following antigens: cd3 (t-lymphocytes), cd4 (t-helpers), cd8 (t-supressors), cd20 (8-lymphocytes), cd25 (il-2 receptor), cd16 (natural killers), cd95 (activated cells ready to apoptosis). |
2002-01-14 |
2023-08-12 |
Not clear |