| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Hodge, P Ha. Effect of intermediate-purity factor VIII (FVIII) concentrate on lymphocyte proliferation and apoptosis: transforming growth factor-beta is a significant immunomodulatory component of FVIII. British journal of haematology. vol 115. issue 2. 2001-12-07. PMID:11703339. |
the presence of pdfviii increased the apoptosis of phytohaemagglutinn (pha) -stimulated cd4 and cd8 t-cell subsets as determined by annexin v binding and dna fragmentation. |
2001-12-07 |
2023-08-12 |
Not clear |
| Y C Yang, T Y Hsu, J Y Chen, C S Yang, R H Li. Tumour necrosis factor-alpha-induced apoptosis in cord blood T lymphocytes: involvement of both tumour necrosis factor receptor types 1 and 2. British journal of haematology. vol 115. issue 2. 2001-12-07. PMID:11703347. |
additionally, cd4(+) t cells showed higher sensitivity to tnfr-mediated apoptosis than cd8(+) t cells. |
2001-12-07 |
2023-08-12 |
human |
| P Secchiero, P Mirandola, D Zella, C Celeghini, A Gonelli, M Vitale, S Capitani, G Zaul. Human herpesvirus 7 induces the functional up-regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) coupled to TRAIL-R1 down-modulation in CD4(+) T cells. Blood. vol 98. issue 8. 2001-12-05. PMID:11588045. |
hhv-7 infection induces apoptosis mostly in uninfected bystander cells but not in productively infected cd4(+) t cells. |
2001-12-05 |
2023-08-12 |
human |
| J Wang, T Chun, J C Lo, Q Wu, Y Wang, A Foster, K Roca, M Chen, K Tamada, L Chen, C R Wang, Y X F. The critical role of LIGHT, a TNF family member, in T cell development. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 9. 2001-12-05. PMID:11673520. |
furthermore, the thymi of light transgenic mice show severe atrophy with remarkably reduced cd4(+)cd8(+) double-positive cells caused by increased apoptosis, suggesting that light can delete immature t cells in vivo. |
2001-12-05 |
2023-08-12 |
mouse |
| L I Terrazas, K L Walsh, D Piskorska, E McGuire, D A Har. The schistosome oligosaccharide lacto-N-neotetraose expands Gr1(+) cells that secrete anti-inflammatory cytokines and inhibit proliferation of naive CD4(+) cells: a potential mechanism for immune polarization in helminth infections. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 9. 2001-12-05. PMID:11673545. |
coculture of naive cd4(+)t cells with gr1(+) suppressor cells did not lead to cd4(+) t cell apoptosis, although it did imprint on naive cd4(+) t cells a response characterized by lower levels of ifn-gamma, coincident with increased il-13 production. |
2001-12-05 |
2023-08-12 |
mouse |
| G Rappl, H Abken, D O Hasselmann, W Tilgen, S Ugurel, U Reinhol. The CD7(-) subset of CD4(+) memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15). Cell death and differentiation. vol 8. issue 4. 2001-12-04. PMID:11550091. |
the cd7(-) subset of cd4(+) memory t cells is prone to accelerated apoptosis that is prevented by interleukin-15 (il-15). |
2001-12-04 |
2023-08-12 |
Not clear |
| G Rappl, H Abken, D O Hasselmann, W Tilgen, S Ugurel, U Reinhol. The CD7(-) subset of CD4(+) memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15). Cell death and differentiation. vol 8. issue 4. 2001-12-04. PMID:11550091. |
here we report that cd4(+)cd7(-) t cells are prone to increased spontaneous apoptosis in vitro compared to cd4(+)cd7(+) t cells. |
2001-12-04 |
2023-08-12 |
Not clear |
| G Rappl, H Abken, D O Hasselmann, W Tilgen, S Ugurel, U Reinhol. The CD7(-) subset of CD4(+) memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15). Cell death and differentiation. vol 8. issue 4. 2001-12-04. PMID:11550091. |
tnf-alpha stimulated fibroblasts rescue cd4(+)cd7(-) t cells from apoptosis whereas unstimulated fibroblasts do not. |
2001-12-04 |
2023-08-12 |
Not clear |
| G Rappl, H Abken, D O Hasselmann, W Tilgen, S Ugurel, U Reinhol. The CD7(-) subset of CD4(+) memory T cells is prone to accelerated apoptosis that is prevented by interleukin-15 (IL-15). Cell death and differentiation. vol 8. issue 4. 2001-12-04. PMID:11550091. |
we conclude that membrane il-15 prevents accelerated apoptosis of cd4(+)cd7(-) t cells. |
2001-12-04 |
2023-08-12 |
Not clear |
| E Guillemard, M T Nugeyre, L Chêne, N Schmitt, C Jacquemot, F Barré-Sinoussi, N Israë. Interleukin-7 and infection itself by human immunodeficiency virus 1 favor virus persistence in mature CD4(+)CD8(-)CD3(+) thymocytes through sustained induction of Bcl-2. Blood. vol 98. issue 7. 2001-12-04. PMID:11568004. |
resistance to apoptosis of sp cd4(+) cells is conferred by a high expression of the il-7 receptor (il-7r) associated with the capacity of il-7 to permanently up-regulate bcl-2. |
2001-12-04 |
2023-08-12 |
human |
| E Guillemard, M T Nugeyre, L Chêne, N Schmitt, C Jacquemot, F Barré-Sinoussi, N Israë. Interleukin-7 and infection itself by human immunodeficiency virus 1 favor virus persistence in mature CD4(+)CD8(-)CD3(+) thymocytes through sustained induction of Bcl-2. Blood. vol 98. issue 7. 2001-12-04. PMID:11568004. |
in contrast, intermediate thymocytes, which replicate the virus at a lower level, are more sensitive to apoptosis, and their differentiation into double-positive cd4(+)cd8(+)cd3(-) (dp cd3(-)) cells strongly increases their death rate on infection. |
2001-12-04 |
2023-08-12 |
human |
| M Castedo, K F Ferri, J Blanco, T Roumier, N Larochette, J Barretina, A Amendola, R Nardacci, D Métivier, J A Este, M Piacentini, G Kroeme. Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. The Journal of experimental medicine. vol 194. issue 8. 2001-12-04. PMID:11602639. |
inhibition of mtor/frap by rapamycin reduces apoptosis in several paradigms of syncytium-dependent death, including in primary cd4(+) lymphoblasts infected by hiv-1. |
2001-12-04 |
2023-08-12 |
human |
| J J Lum, A A Pilon, J Sanchez-Dardon, B N Phenix, J E Kim, J Mihowich, K Jamison, N Hawley-Foss, D H Lynch, A D Badle. Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l. Journal of virology. vol 75. issue 22. 2001-12-04. PMID:11602752. |
by contrast, such treatment induces apoptosis of in vitro hiv-infected mdm as well as peripheral blood lymphocytes from hiv-infected patients, including cd4(+) cd45ro(+) hla-dr(-) lymphocytes. |
2001-12-04 |
2023-08-12 |
human |
| S Vallabhapurapu, R P Ryseck, M Malewicz, D S Weih, F Wei. Inhibition of NF-kappaB in T cells blocks lymphoproliferation and partially rescues autoimmune disease in gld/gld mice. European journal of immunology. vol 31. issue 9. 2001-10-25. PMID:11536159. |
transgenic gld/gld mice expressing a non-degradable form of ikappabalpha under the control of t cell-specific regulatory elements show dramatically reduced lymphadenopathy, splenomegaly, and an almost complete elimination of thy-1(+)b220(+)cd4(-)cd8(-) abnormal t cells, correlating with reduced proliferative responses and increased apoptosis of peripheral t cells upon tcr triggering. |
2001-10-25 |
2023-08-12 |
mouse |
| L Caccavelli, A C Field, V Betin, L Dreillard, M F Belair, M F Bloch, P Bruneval, M Kazatchkine, B Bello. Normal IgG protects against acute graft-versus-host disease by targeting CD4(+)CD134(+) donor alloreactive T cells. European journal of immunology. vol 31. issue 9. 2001-10-25. PMID:11536177. |
we further demonstrate that protection was associated with a decrease in cd4(+) t cells bearing the activation marker cd134 in vivo, and with an enhanced apoptosis of activated cd4(+) t cells by ivig, in vitro. |
2001-10-25 |
2023-08-12 |
rat |
| L Caccavelli, A C Field, V Betin, L Dreillard, M F Belair, M F Bloch, P Bruneval, M Kazatchkine, B Bello. Normal IgG protects against acute graft-versus-host disease by targeting CD4(+)CD134(+) donor alloreactive T cells. European journal of immunology. vol 31. issue 9. 2001-10-25. PMID:11536177. |
our observations suggest that the prevention of agvhd by ivig in this model is mediated by the induction of apoptosis of activated alloreactive cd4(+)cd134(+) donor t cells. |
2001-10-25 |
2023-08-12 |
rat |
| D H Dockrel. Apoptotic cell death in the pathogenesis of infectious diseases. The Journal of infection. vol 42. issue 4. 2001-10-25. PMID:11545564. |
infection with hiv results in enhanced levels of cd4 t-lymphocyte apoptosis in both directly infected cells and in uninfected bystander cells. |
2001-10-25 |
2023-08-12 |
human |
| D H Dockrel. Apoptotic cell death in the pathogenesis of infectious diseases. The Journal of infection. vol 42. issue 4. 2001-10-25. PMID:11545564. |
a number of different pathways induce hiv-associated cd4 t-lymphocyte apoptosis and apoptosis of uninfected bystander cells is particularly associated with increased susceptibility to fas. |
2001-10-25 |
2023-08-12 |
human |
| S Bregenholt, T R Petersen, M H Claesso. The majority of lamina propria CD4(+) T-cells from scid mice with colitis undergo Fas-mediated apoptosis in vivo. Immunology letters. vol 78. issue 1. 2001-10-11. PMID:11470145. |
the majority of lamina propria cd4(+) t-cells from scid mice with colitis undergo fas-mediated apoptosis in vivo. |
2001-10-11 |
2023-08-12 |
mouse |
| S Bregenholt, T R Petersen, M H Claesso. The majority of lamina propria CD4(+) T-cells from scid mice with colitis undergo Fas-mediated apoptosis in vivo. Immunology letters. vol 78. issue 1. 2001-10-11. PMID:11470145. |
colitis is accompanied by activation and apoptosis of fas ligand and tnf-alpha expressing cd4(+) t-cells in the diseased colonic lamina propria (eur. |
2001-10-11 |
2023-08-12 |
mouse |