| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clare E Futter, Jonathan G Crowston, Bruce D S Alla. Interaction with collagen IV protects lens epithelial cells from Fas-dependent apoptosis by stimulating the production of soluble survival factors. Investigative ophthalmology & visual science. vol 46. issue 9. 2005-11-02. PMID:16123427. |
to investigate the sensitivity of lens epithelial cells (lecs) to fas-dependent apoptosis and to determine the role of interaction with the extracellular matrix (ecm) in the regulation of fas-dependent apoptosis. |
2005-11-02 |
2023-08-12 |
Not clear |
| Thomas W Johnson, Yin Xiong Wu, Christian Herdeg, Andreas Baumbach, Andrew C Newby, Karl R Karsch, Martin Oberhof. Stent-based delivery of tissue inhibitor of metalloproteinase-3 adenovirus inhibits neointimal formation in porcine coronary arteries. Arteriosclerosis, thrombosis, and vascular biology. vol 25. issue 4. 2005-10-31. PMID:15681295. |
radtimp-3 decreased smooth muscle cell migration, stabilized the extracellular matrix, and uniquely promoted apoptosis. |
2005-10-31 |
2023-08-12 |
Not clear |
| Ana Cristina García-Ulloa, Oscar Arriet. Tubal occlusion causing infertility due to an excessive inflammatory response in patients with predisposition for keloid formation. Medical hypotheses. vol 65. issue 5. 2005-10-27. PMID:16005574. |
this keloid scarring involves an excess in extracellular matrix production and inhibition of apoptosis, for which a several growth factors and interleukins are needed. |
2005-10-27 |
2023-08-12 |
Not clear |
| M Fini, G Giavaresi, A Carpi, A Nicolini, S Setti, R Giardin. Effects of pulsed electromagnetic fields on articular hyaline cartilage: review of experimental and clinical studies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 59. issue 7. 2005-10-27. PMID:16084055. |
controlling chondrocyte death and apoptosis, function, response to anabolic and catabolic stimuli, matrix synthesis or degradation and inflammation is the most important target of potential chondroprotective treatment, aimed to retard or stabilize the progression of oa. |
2005-10-27 |
2023-08-12 |
Not clear |
| M Yu Kapitonova, Othman Manso. Ultrastructural changes of the articular cartilage in some arthropathies with special reference to chondrocyte cell death. The Malaysian journal of pathology. vol 25. issue 1. 2005-10-27. PMID:16196374. |
to determine in situ using tem the balance of apoptosis and necrosis in the articular cartilage of patients with inflammatory (rheumatoid arthritis and seronegative spondyloarthritis) and degenerative (osteoarthritis) joint diseases and to establish possible correlation between the cell death rate and the matrix vesicles formation. |
2005-10-27 |
2023-08-12 |
Not clear |
| Robert Terkeltaub, Kristen Johnson, Anne Murphy, Soumitra Ghos. Invited review: the mitochondrion in osteoarthritis. Mitochondrion. vol 1. issue 4. 2005-10-20. PMID:16120285. |
these include oxidative stress, inadequacy of chondrocyte biosynthetic and growth responses, up-regulated chondrocyte cytokine-induced inflammation and matrix catabolism, increased chondrocyte apoptosis, and pathologic cartilage matrix calcification. |
2005-10-20 |
2023-08-12 |
Not clear |
| Chithan Kandaswami, Chithan Kanadaswami, Lung-Ta Lee, Ping-Ping H Lee, Jiuan-Jiuan Hwang, Ferng-Chun Ke, Ying-Tung Huang, Ming-Ting Le. The antitumor activities of flavonoids. In vivo (Athens, Greece). vol 19. issue 5. 2005-10-18. PMID:16097445. |
in vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. |
2005-10-18 |
2023-08-12 |
human |
| Stephan Kusick, Helga Bertram, Hans Oberleithner, Thomas Ludwi. Nanoscale imaging and quantification of local proteolytic activity. Journal of cellular physiology. vol 204. issue 3. 2005-10-06. PMID:15744770. |
proteolytic cleavage of extracellular matrix (ecm) is a critical feature of tumor cell invasion, and affects cancer cell growth, differentiation, apoptosis, and migration. |
2005-10-06 |
2023-08-12 |
Not clear |
| Irfan Rahma. The role of oxidative stress in the pathogenesis of COPD: implications for therapy. Treatments in respiratory medicine. vol 4. issue 3. 2005-10-06. PMID:15987234. |
these include oxidative inactivation of antiproteases and surfactants, mucus hypersecretion, membrane lipid peroxidation, mitochondrial respiration, alveolar epithelial injury, remodeling of extracellular matrix, and apoptosis. |
2005-10-06 |
2023-08-12 |
Not clear |
| Thomas Effert. Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. vol 8. issue 1-2. 2005-10-05. PMID:15878303. |
these genes are from classes with different biological function; for example, regulation of proliferation (bub3, cyclins, cdc25a), angiogenesis (vascular endothelial growth factor and its receptor, matrix metalloproteinase-9, angiostatin, thrombospondin-1) or apoptosis (bcl-2, bax). |
2005-10-05 |
2023-08-12 |
human |
| R G Humphrey, S D Smith, L Pang, Y Sadovsky, D M Nelso. Fibrin enhances differentiation, but not apoptosis, and limits hypoxic injury of cultured term human trophoblasts. Placenta. vol 26. issue 6. 2005-10-05. PMID:15950063. |
compared to the two controls, fibrin matrix had no effect on trophoblast apoptosis or total cell death in standard conditions. |
2005-10-05 |
2023-08-12 |
human |
| Vaiva Lesauskaite, Laima Ivanoviene, Angelija Valanciūt. [Programmed cellular death and atherogenesis: from molecular mechanisms to clinical aspects]. Medicina (Kaunas, Lithuania). vol 39. issue 6. 2005-09-30. PMID:12829874. |
by contrast, apoptosis of macrophages diminishes the production of matrix methaloproteinases that decompose collagen fibers. |
2005-09-30 |
2023-08-12 |
Not clear |
| V T Solovyan, J Keski-Oj. Apoptosis of human endothelial cells is accompanied by proteolytic processing of latent TGF-beta binding proteins and activation of TGF-beta. Cell death and differentiation. vol 12. issue 7. 2005-09-29. PMID:15818397. |
we report here that apoptosis of human umbilical vein endothelial cells (huvecs) is accompanied by release of truncated large latent tgf-beta complexes from the pericellular matrix followed by activation of tgf-beta. |
2005-09-29 |
2023-08-12 |
human |
| Takahiro Tsuruki, Kyoya Takahata, Masaaki Yoshikaw. Anti-alopecia mechanisms of soymetide-4, an immunostimulating peptide derived from soy beta-conglycinin. Peptides. vol 26. issue 5. 2005-09-27. PMID:15808899. |
these results suggest that pge2, which is produced after activation of cox by soymetide-4, might suppress apoptosis of hair matrix cells and etoposide-induced alopecia by activating nf-kappab. |
2005-09-27 |
2023-08-12 |
rat |
| Albert C M Ong, Peter C Harri. Molecular pathogenesis of ADPKD: the polycystin complex gets complex. Kidney international. vol 67. issue 4. 2005-09-26. PMID:15780076. |
the cystogenic process is highly complex with a cellular phenotype consistent with "dedifferentiation" (i.e., a high proliferative rate, increased apoptosis, altered protein sorting, changed secretory characteristics, and disorganization of the extracellular matrix). |
2005-09-26 |
2023-08-12 |
human |
| Mei-Yu Hsu, Sherry Rovinsky, Sunita Penmatcha, Meenhard Herlyn, Desirae Muirhea. Bone morphogenetic proteins in melanoma: angel or devil? Cancer metastasis reviews. vol 24. issue 2. 2005-09-26. PMID:15986135. |
bone morphogenetic proteins (bmps) are members of the transforming growth factor-beta (tgf-beta) superfamily serving multiple functions in many cell and tissue types including proliferation, apoptosis, differentiation, chemotaxis, angiogenesis, and matrix production during embryogenic development as well as in adult life. |
2005-09-26 |
2023-08-12 |
human |
| Liezhen Fu, Atsuko Ishizuya-Oka, Daniel R Buchholz, Tosikazu Amano, Hiroki Matsuda, Yun-Bo Sh. A causative role of stromelysin-3 in extracellular matrix remodeling and epithelial apoptosis during intestinal metamorphosis in Xenopus laevis. The Journal of biological chemistry. vol 280. issue 30. 2005-09-22. PMID:15929979. |
a causative role of stromelysin-3 in extracellular matrix remodeling and epithelial apoptosis during intestinal metamorphosis in xenopus laevis. |
2005-09-22 |
2023-08-12 |
xenopus_laevis |
| Ana Fortuño, Gorka San José, María U Moreno, Javier Díez, Guillermo Zalb. Oxidative stress and vascular remodelling. Experimental physiology. vol 90. issue 4. 2005-09-21. PMID:15890797. |
reactive oxygen species participate in growth, apoptosis and migration of vascular smooth muscle cells, in the modulation of endothelial function, including endothelium-dependent relaxation and expression of proinflammatory phenotype, and in the modification of the extracellular matrix. |
2005-09-21 |
2023-08-12 |
human |
| S S Prime, M Pring, M Davies, I C Paterso. TGF-beta signal transduction in oro-facial health and non-malignant disease (part I). Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists. vol 15. issue 6. 2005-09-20. PMID:15574677. |
the transforming growth factor-beta (tgf-beta) family of cytokines consists of multi-functional polypeptides that regulate a variety of cell processes, including proliferation, differentiation, apoptosis, extracellular matrix elaboration, angiogenesis, and immune suppression, among others. |
2005-09-20 |
2023-08-12 |
Not clear |
| Richard Seonghun Nho, Hong Xia, Judy Kahm, Jill Kleidon, Deanna Diebold, Craig A Henk. Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a beta1 integrin viability signaling pathway. The Journal of biological chemistry. vol 280. issue 28. 2005-09-12. PMID:15905178. |
here, we show that ilk activity decreased in response to collagen matrix contraction, which correlated with akt dephosphorylation and induction of fibroblast apoptosis. |
2005-09-12 |
2023-08-12 |
Not clear |